Dr. Jeremy Brown, currently Director of Emergency Care Research at the National Institutes of Health, expounds on the flu's deadly past to solve the mysteries that could protect us from the next outbreak. In Influenza, he talks with leading epidemiologists, policy makers, and the researcher who first sequenced the genetic building blocks of the original 1918 virus to offer both a comprehensive history and a roadmap for understanding what’s to come.Dr. Brown digs into the discovery and resurrection of the flu virus in the frozen victims of the 1918 epidemic, as well as the bizarre remedies that once treated the disease, such as whiskey and blood-letting. Influenza also breaks down the current dialogue surrounding the disease, explaining the controversy over vaccinations, antiviral drugs like Tamiflu, and the federal government’s role in preparing for pandemic outbreaks. Though 100 years of advancement in medical research and technology have passed since the 1918 disaster, Dr. Brown warns that many of the most vital questions about the flu virus continue to confound even the leading experts.Influenza is an enlightening and unnerving look at a shapeshifting deadly virus that has been around long before people—and warns us that it may be many more years before we are able to conquer it for good.

    The media seized hold of the story and, in the process, helped to launch one of the most devastating health scares ever. In the years to come Wakefield would be revealed as a profiteer in league with class-action lawyers, and he would eventually lose his medical license. Meanwhile, one study after another failed to find any link between childhood vaccines and autism. Yet the myth that vaccines somehow cause developmental disorders lives on. Despite the lack of corroborating evidence, it has been popularized by media personalities such as Oprah Winfrey and Jenny McCarthy and legitimized by journalists who claim that they are just being fair to “both sides” of an issue about which there is little debate. Meanwhile, millions of dollars have been diverted from potential breakthroughs in autism research; families have spent their savings on ineffective “miracle cures"; and declining vaccination rates have led to outbreaks of deadly illnesses like Hib, measles, and whooping cough. Most tragic of all is the increasing number of children dying from vaccine-preventable diseases. In The Panic Virus Seth Mnookin draws on interviews with parents, public-health advocates, scientists, and anti-vaccine activists to tackle a fundamental question: How do we decide what the truth is? The fascinating answer helps explain everything from the persistence of conspiracy theories about 9/11 to the appeal of talk-show hosts who demand that President Obama “prove” he was born in America. The Panic Virus is the ultimate cautionary tale for our time.

    The disaster not only changed the world’s perception of nuclear power and the science that spawned it, but also our understanding of the planet’s delicate ecology. With the images of the abandoned homes and playgrounds beyond the barbed wire of the 30-kilometer Exclusion Zone, the rusting graveyards of contaminated trucks and helicopters, the farmland lashed with black rain, the event fixed for all time the notion of radiation as an invisible killer.Chernobyl was also a key event in the destruction of the Soviet Union, and, with it, the United States’ victory in the Cold War. For Moscow, it was a political and financial catastrophe as much as an environmental and scientific one. With a total cost of 18 billion rubles—at the time equivalent to $18 billion—Chernobyl bankrupted an already teetering economy and revealed to its population a state built upon a pillar of lies. The full story of the events that started that night in the control room of Reactor No.4 of the V.I. Lenin Nuclear Power Plant has never been told—until now. Through two decades of reporting, new archival information, and firsthand interviews with witnesses, journalist Adam Higginbotham tells the full dramatic story, including Alexander Akimov and Anatoli Dyatlov, who represented the best and worst of Soviet life; denizens of a vanished world of secret policemen, internal passports, food lines, and heroic self-sacrifice for the Motherland. Midnight in Chernobyl, award-worthy nonfiction that reads like sci-fi, shows not only the final epic struggle of a dying empire but also the story of individual heroism and desperate, ingenious technical improvisation joining forces against a new kind of enemy.

    But the deeper history of Amsterdam, what makes it one of the most fascinating places on earth, is bound up in its unique geography-the constant battle of its citizens to keep the sea at bay and the democratic philosophy that this enduring struggle fostered. Amsterdam is the font of liberalism, in both its senses. Tolerance for free thinking and free love make it a place where, in the words of one of its mayors, "craziness is a value." But the city also fostered the deeper meaning of liberalism, one that profoundly influenced America: political and economic freedom. Amsterdam was home not only to religious dissidents and radical thinkers but to the world's first great global corporation. In this effortlessly erudite account, Russell Shorto traces the idiosyncratic evolution of Amsterdam, showing how such disparate elements as herring anatomy, naked Anabaptists parading through the streets, and an intimate gathering in a sixteenth-century wine-tasting room had a profound effect on Dutch-and world-history. Weaving in his own experiences of his adopted home, Shorto provides an ever-surprising, intellectually engaging story of Amsterdam from the building of its first canals in the 1300s, through its brutal struggle for independence, its golden age as a vast empire, to its complex present in which its cherished ideals of liberalism are under siege.

    However, four royal women, related in family and in court ties—Joan of Navarre, Eleanor Cobham, Jacquetta of Luxembourg and Elizabeth Woodville—were accused of practicing witchcraft in order to kill or influence the king.Some of these women may have turned to the “dark arts” in order to divine the future or obtain healing potions, but the purpose of the accusations was purely political. Despite their status, these women were vulnerable because of their gender, as the men around them moved them like pawns for political gains.In Royal Witches, Gemma Hollman explores the lives and the cases of these so-called witches, placing them in the historical context of fifteenth-century England, a setting rife with political upheaval and war. In a time when the line between science and magic was blurred, these trials offer a tantalizing insight into how malicious magic would be used and would later cause such mass hysteria in centuries to come.

    The citadel of power, privilege and breeding in which the titled, land-owning governing class had barricaded itself for so long was breached. The incomers were a group of young women who, fifty years earlier, would have been looked on as the alien denizens of another world - the New World, to be precise. From 1874 - the year that Jennie Jerome, the first known 'Dollar Princess', married Randolph Churchill - to 1905, dozens of young American heiresses married into the British peerage, bringing with them all the fabulous wealth, glamour and sophistication of the Gilded Age.Anne de Courcy sets the stories of these young women and their families in the context of their times. Based on extensive first-hand research, drawing on diaries, memoirs and letters, this richly entertaining group biography reveals what they thought of their new lives in England - and what England thought of them.

    Operation Fortitude, which protected and enabled the invasion, and the Double Cross system, which specialized in turning German spies into double agents, deceived the Nazis into believing that the Allies would attack at Calais and Norway rather than Normandy. It was the most sophisticated and successful deception operation ever carried out, ensuring that Hitler kept an entire army awaiting a fake invasion, saving thousands of lives, and securing an Allied victory at the most critical juncture in the war.   The story of D-Day has been told from the point of view of the soldiers who fought in it, the tacticians who planned it, and the generals who led it. But this epic event in world history has never before been told from the perspectives of the key individuals in the Double Cross System. These include its director (a brilliant, urbane intelligence officer), a colorful assortment of MI5 handlers (as well as their counterparts in Nazi intelligence), and the five spies who formed Double Cross’s nucleus: a dashing  Serbian playboy, a Polish fighter-pilot, a bisexual Peruvian party girl, a deeply eccentric Spaniard with a diploma in chicken farming and a volatile Frenchwoman, whose obsessive love for her pet dog very nearly wrecked the entire plan. The D-Day spies were, without question, one of the oddest military units ever assembled, and their success depended on the delicate, dubious relationship between spy and spymaster, both German and British. Their enterprise was saved from catastrophe by a shadowy sixth spy whose heroic sacrifice is revealed here for the first time.   With the same depth of research, eye for the absurd and masterful storytelling that have made Ben Macintyre an international bestseller,  Double Cross is a captivating narrative of the spies who wove a web so intricate it ensnared Hitler’s army and carried thousands of D-Day troops across the Channel in safety.

    But sometimes, when obsession gets the better of scientists, they twist a noble pursuit into something sinister. Under this spell, knowledge isn’t everything, it’s the only thing—no matter the cost. Bestselling author Sam Kean tells the true story of what happens when unfettered ambition pushes otherwise rational men and women to cross the line in the name of science, trampling ethical boundaries and often committing crimes in the process.The Icepick Surgeon masterfully guides the reader across two thousand years of history, beginning with Cleopatra’s dark deeds in ancient Egypt. The book reveals the origins of much of modern science in the transatlantic slave trade of the 1700s, as well as Thomas Edison’s mercenary support of the electric chair and the warped logic of the spies who infiltrated the Manhattan Project. But the sins of science aren’t all safely buried in the past. Many of them, Kean reminds us, still affect us today. We can draw direct lines from the medical abuses of Tuskegee and Nazi Germany to current vaccine hesitancy, and connect icepick lobotomies from the 1950s to the contemporary failings of mental-health care. Kean even takes us into the future, when advanced computers and genetic engineering could unleash whole new ways to do one another wrong.Unflinching, and exhilarating to the last page, The Icepick Surgeon fuses the drama of scientific discovery with the illicit thrill of a true-crime tale. With his trademark wit and precision, Kean shows that, while science has done more good than harm in the world, rogue scientists do exist, and when we sacrifice morals for progress, we often end up with neither.

    Bell ruling made government sterilization of "undesirable" citizens the law of the land. New York Times bestselling author Adam Cohen tells the story in Imbeciles of one of the darkest moments in the American legal tradition: the Supreme Court's decision to champion eugenic sterilization for the greater good of the country. In 1927, when the nation was caught up in eugenic fervor, the justices allowed Virginia to sterilize Carrie Buck, a perfectly normal young woman, for being an "imbecile." It is a story with many villains, from the superintendent of the Dickensian Virginia Colony for Epileptics and Feebleminded who chose Carrie for sterilization to the former Missouri agriculture professor and Nazi sympathizer who was the nation's leading advocate for eugenic sterilization. But the most troubling actors of all were the eight Supreme Court justices who were in the majority--including William Howard Taft, the former president; Louis Brandeis, the legendary progressive; and Oliver Wendell Holmes, Jr., America's most esteemed justice, who wrote the decision urging the nation to embark on a program of mass eugenic sterilization

    Drawing on sources as diverse as monastic manuscripts and dendrochronological studies (which measure growth rings in trees), historian Robert S. Gottfried demonstrates how a bacillus transmitted by rat fleas brought on an ecological reign of terror—killing one European in three, wiping out entire villages and towns, and rocking the foundation of medieval society and civilization.

    Most biographies focus on the years of her reign, during which she proved herself as adept a ruler -- and as shrewd an operator -- as England had ever seen. But while the history of her rule is fascinating, the story of how her remarkable character was forged seems vital to a full understanding of the woman who led England into a new age of prosperity, power, and artistic achievement. David Starkey's Elizabeth: The Struggle for the Throne explores the terra incognita of Elizabeth's early years, and the result is nothing short of captivating.Starkey finds that Elizabeth's early years ran the gamut from days of snug security as the daughter of Henry VIII and Anne Boleyn, and Henry's heir apparent, to the years of uncertainty after her mother's execution whenElizabeth was separated from court and virtually forgotten. She received a first-rate academic education, excelling in languages and rhetoric and exhibiting a strong interest in the Protestant religion her father had established in England. But the education she received from life itself would prove far more valuable for the monarch-to-be. After the death of Henry VIII and Edward VI (Elizabeth's half brother), Elizabeth's status as sister and would-be successor to the Catholic queen Mary put her in a dangerous position.It also put her in prison at Mary's command -- and perilously close to execution -- after plots to place Elizabeth on the throne were revealed. Starkey makes it clear that while others may have actually done the dirty work, Elizabeth was usually in the thick of these efforts. Her imprisonment taught her to cover her tracks, but it did not stop her maneuverings. While fervently professing her Catholic faith, she surrounded herself with Protestant advisers and attendants, and bided her time. She evaded another snare of her sister's when Mary attempted to neutralize Elizabeth by marrying her off to a Catholic Spaniard in exchange for naming Elizabeth her successor. Perhaps Elizabeth had learned early on from the plight of her mother that marriage had its drawbacks. Starkey, however, suggests that Elizabeth, in a moment of true regality, would not accept the crown if it came through bullying and capitulation. Again, Elizabeth bided her time.Her seeming patience -- for Starkey reveals that Elizabeth continued to plot -- paid off when Mary, never robust, entered her final illness. Elizabeth managed to convince the now irrational queen that she was, indeed, a staunch Catholic and vowed to preserve England as a Catholic realm. Upon Mary's death, Elizabeth ascended to the throne with no meaningful opposition, thereby beginning what would be a golden age, one of the most legendary reigns in history. Starkey lets us understand, for the first time, the forces that made her into the formidable woman -- and brilliant ruler -- that she would soon prove to be.

    Vaccines and antibiotics, the mainstays of modern medicine, have not been able to conquer infectious microbes because of their amazing ability to adapt, evolve, and spread to new places. Terrorism aside, one of the greatest dangers from infectious disease we face today is from a massive outbreak of drug-resistant microbes.Deadly Outbreaks recounts the scientific adventures of a special group of intrepid individuals who investigate these outbreaks around the world and figure out how to stop them. Part homicide detective, part physician, these medical investigators must view the problem from every angle, exhausting every possible source of contamination. Any data gathered in the field must be stripped of human sorrows and carefully analyzed into hard statistics.Author Dr. Alexandra Levitt is an expert on emerging diseases and other public health threats. Here she shares insider accounts she’s collected that go behind the alarming headlines we’ve seen in the media: mysterious food poisonings, unexplained deaths at a children’s hospital, a strange neurologic disease afflicting slaughterhouse workers, flocks of birds dropping dead out of the sky, and drug-resistant malaria running rampant in a refugee camp. Meet the resourceful investigators—doctors, veterinarians, and research scientists—and discover the truth behind these cases and more.

    It is a fiery history of Queens, the perils of power and of how the Wars of the Roses were ended – not by knights in battle, but the sinewy political skills of women.The events of the Wars of the Roses are usually described in terms of the men involved; Richard, Duke of York, Henry VI, Edward IV and Henry VII. The reality though, argues Sarah Gristwood, was quite different. These years were also packed with women's drama and – in the tales of conflicted maternity and monstrous births – alive with female energy.In this completely original book, acclaimed author Sarah Gristwood sheds light on a neglected dimension of English history: the impact of Tudor women on the Wars of the Roses. She examines Cecily Neville, the wife of Richard Duke of York, who was deprived of being queen when her husband died at the Battle of Wakefield; Elizabeth Woodville, a widow with several children who married Edward IV in secret and was crowned queen consort; Margaret Beaufort, mother of Henry VII, whose ambitions centred on her son and whose persuasions are likely to have lead her husband Lord Stanley, previously allied with the Yorkists, to play his part in Henry's victory.Until now, the lives of these women have remained little known to the general public. Sarah Gristwood tells their stories in detail for the first time. Captivating and original, this is historical writing of the most important kind.

    There have been other books on Dr Morell's cocktail of treatments for Hitler and Goering's reliance on drugs, but Ohler's book is the first to show how the entire Nazi regime was permeated with drugs - cocaine, heroin, morphine and methamphetamines, the last of these crucial to troops' resilience and partly explaining German victory in 1940. Ohler is explicit that drugs cannot explain Third Reich ideology, but their promiscuous use impaired and confused decision-making, with drastic effects on Hitler and his entourage, who, as the war turned against Germany, took refuge in ever more poorly understood cocktails of stimulants. This chemical euphoria changes how we should think about the Nazi high command and its ability to understand the situation it found itself in by 1944-45. As such Blitzed will force a wider reinterpretation of several key events during the Second World War.

    It accommodates four of our five senses, encases the brain, and boasts the most expressive set of muscles in the body. It is our most distinctive attribute and connects our inner selves to the outer world. Yet there is a dark side to the head’s preeminence, one that has, in the course of human history, manifested itself in everything from decapitation to headhunting. So explains anthropologist Frances Larson in this fascinating history of decapitated human heads. From the Western collectors whose demand for shrunken heads spurred massacres to Second World War soldiers who sent the remains of the Japanese home to their girlfriends, from Madame Tussaud modeling the guillotined head of Robespierre to Damien Hirst photographing decapitated heads in city morgues,from grave-robbing phrenologists to skull-obsessed scientists, Larson explores our macabre fixation with severed heads.