The latest studies are revealing exciting new discoveries, such as how the DNA and related chemical compounds in our cells work together to direct the processes of life. Scientists are not only unraveling how life evolved in the ancient past, but are also finding the keys to creating a healthier future.  How does the minuscule chemical cluster in each of our 100 trillion cells accomplish the amazing feat of creating and maintaining our bodies? Frank Ryan, a physician and an evolutionary biologist, describes the complex ways in which the genome operates as a holistic system and not solely through genes coding for proteins—the building blocks of life. Also involved are elaborate switching mechanisms that regulate and control portions of our DNA, as well as the interplay of retroviruses and bacteria.This groundbreaking book explains that we are on the cusp of an amazing era of disease treatment and eradication.

    And yet, until very recently, scientists believed our brains were fully developed from childhood on. Now, thanks to imaging technology that enables us to look inside the living human brain at all ages, we know that this isn't so. Professor Sarah-Jayne Blakemore, one of the world's leading researchers into adolescent neurology, explains precisely what is going on in the complex and fascinating brains of teenagers--namely that the brain goes on developing and changing right through adolescence--with profound implications for the adults these young people will become.Drawing from cutting-edge research, including her own, Blakemore shows:How an adolescent brain differs from those of children and adultsWhy problem-free kids can turn into challenging teensWhat drives the excessive risk-taking and all-consuming relationships common among teenagersAnd why many mental illnesses--depression, addiction, schizophrenia--present during these formative yearsBlakemore's discoveries have transformed our understanding of the teenage mind, with consequences for law, education policy and practice, and, most of all, parents.

    In all the current highly publicized debates about creationism and its descendant "intelligent design," there is an element of the controversy that is rarely mentioned—the "evidence," the empirical truth of evolution by natural selection. Even Richard Dawkins and Stephen Jay Gould, while extolling the beauty of evolution and examining case studies, have not focused on the evidence itself. Yet the proof is vast, varied, and magnificent, drawn from many different fields of science. Scientists are observing species splitting into two and are finding more and more fossils capturing change in the past—dinosaurs that have sprouted feathers, fish that have grown limbs. Why Evolution Is True weaves together the many threads of modern work in genetics, paleontology, geology, molecular biology, and anatomy that demonstrate the "indelible stamp" of the processes first proposed by Darwin. In crisp, lucid prose accessible to a wide audience, Why Evolution Is True dispels common misunderstandings and fears about evolution and clearly confirms that this amazing process of change has been firmly established as a scientific truth.

    What is going on? Anatomy of an Epidemic challenges readers to think through that question themselves. First, Whitaker investigates what is known today about the biological causes of mental disorders. Do psychiatric medications fix “chemical imbalances” in the brain, or do they, in fact, create them? Researchers spent decades studying that question, and by the late 1980s, they had their answer. Readers will be startled—and dismayed—to discover what was reported in the scientific journals. Then comes the scientific query at the heart of this book: During the past fifty years, when investigators looked at how psychiatric drugs affected long-term outcomes, what did they find? Did they discover that the drugs help people stay well? Function better? Enjoy good physical health? Or did they find that these medications, for some paradoxical reason, increase the likelihood that people will become chronically ill, less able to function well, more prone to physical illness?  This is the first book to look at the merits of psychiatric medications through the prism of long-term results. Are long-term recovery rates higher for medicated or unmedicated schizophrenia patients? Does taking an antidepressant decrease or increase the risk that a depressed person will become disabled by the disorder? Do bipolar patients fare better today than they did forty years ago, or much worse? When the National Institute of Mental Health (NIMH) studied the long-term outcomes of children with ADHD, did they determine that stimulants provide any benefit?  By the end of this review of the outcomes literature, readers are certain to have a haunting question of their own: Why have the results from these long-term studies—all of which point to the same startling conclusion—been kept from the public?  In this compelling history, Whitaker also tells the personal stories of children and adults swept up in this epidemic. Finally, he reports on innovative programs of psychiatric care in Europe and the United States that are producing good long-term outcomes. Our nation has been hit by an epidemic of disabling mental illness, and yet, as Anatomy of an Epidemic reveals, the medical blueprints for curbing that epidemic have already been drawn up.

    It’s everywhere we look, but seldom seen—until now. Found in Translation reveals the surprising and complex ways that translation shapes the world. Covering everything from holy books to hurricane warnings and poetry to peace treaties, Nataly Kelly and Jost Zetzsche offer language lovers and pop culture fans alike an insider’s view of the ways in which translation spreads culture, fuels the global economy, prevents wars, and stops the outbreak of disease. Examples include how translation plays a key role at Google, Facebook, NASA, the United Nations, the Olympics, and more.

    With more than one in every five people over the age of fourteen addicted, drug abuse has been called the most formidable health problem worldwide. If we are not victims ourselves, we all know someone struggling with the merciless compulsion to alter their experience by changing how their brain functions.Drawing on years of research--as well as personal experience as a recovered addict--researcher and professor Judy Grisel has reached a fundamental conclusion: for the addict, there will never be enough drugs. The brain's capacity to learn and adapt is seemingly infinite, allowing it to counteract any regular disruption, including that caused by drugs. What begins as a normal state punctuated by periods of being high transforms over time into a state of desperate craving that is only temporarily subdued by a fix, explaining why addicts are unable to live either with or without their drug. One by one, Grisel shows how different drugs act on the brain, the kind of experiential effects they generate, and the specific reasons why each is so hard to kick.Grisel's insights lead to a better understanding of the brain's critical contributions to addictive behavior, and will help inform a more rational, coherent, and compassionate response to the epidemic in our homes and communities.

    When death is sudden or unexplained, it falls to Shepherd to establish the cause. Each post-mortem is a detective story in its own right - and Shepherd has performed over 23,000 of them. Through his skill, dedication and insight, Dr Shepherd solves the puzzle to answer our most pressing question: how did this person die?From serial killer to natural disaster, 'perfect murder' to freak accident, Shepherd takes nothing for granted in pursuit of truth. And while he's been involved in some of the most high-profile cases of recent times, it's often the less well known encounters that prove the most perplexing, intriguing and even bizarre. In or out of the public eye, his evidence has put killers behind bars, freed the innocent and turned open-and-shut cases on their heads.But a life in death, bearing witness to some of humanity's darkest corners, exacts a price and Shepherd doesn't flinch from counting the cost to him and his family.

    In this groundbreaking book, Goodavage brings us behind the scenes of cutting-edge science at top research centers, and into the lives of people whose well-being depends on their devoted, highly skilled personal MDs (medical dogs). With her signature wit and passion, Goodavage explores how doctor dogs are becoming our happy allies in the fight against dozens of physical and mental conditions.We meet dogs who detect cancer and Parkinson's disease, and dogs who alert people to seizures and diabetic lows or highs and other life-threatening physical ailments. Goodavage reveals the revolutionary ways dogs are helping those with autism, anxiety, depression, schizophrenia, and post-traumatic stress disorder. And she introduces us to intrepid canines who are protecting us from antibiotic-resistant bugs, and to dogs who may one day help keep us safe from epidemic catastrophe. Their paycheck for their lifesaving work? Heartfelt praise and a tasty treat or favorite toy.The emotional element in Doctor Dogs delivers as powerfully as the science. You don't have to be a dog lover to care deeply about what these dogs are doing and what we are learning from them--although if you're not a dog lover, you probably will be by the end of the book.

     In her newest collection, Moore selects essays that celebrate the music of the natural world as a reminder of what can be taken from us—the yowl of wolves, tick of barnacles, laughter of children, shriek of falling mountains. Alongside these selections are brand new essays born from the sorrow and iniquity of this new age of extinction, all bearing witness to the glories of this world and the sins against it. Each group of essays moves, as Moore herself has been moved, from celebration to lamentation to bewilderment to the determination to act.In Earth's Wild Music, Moore reminds us that whatever is left of the planet after its pillaging is the world in which those who remain must live. Whatever genetic song-lines, whatever fragments of whale-squeal and shattered harmonies are left, that's what evolution will have to work with. Music is the shivering urgency and exuberance of life on-going. In a time of terrible silencing, Moore asks, who will forgive us if we do not save the songs?

    In fact, a plethora of parasites affect our behavior in ways we have barely begun to understand.  In this mind-bending book, McAuliffe reveals the eons-old war between parasites and other creatures that is playing out in our very own bodies. And more surprising still, she uncovers the decisive role that parasites may have played in the rise and demise of entire civilizations. Our obsession with cleanliness and our experience of disgust are both evolutionary tools for avoiding infection, but they evolved differently for different populations. Political, social, and religious differences among societies may be caused, in part, by the different parasites that prey on us. In the tradition of Jared Diamond’s Guns, Germs, and Steel and Neil Shubin’s Your Inner Fish, This Is Your Brain on Parasites is both a journey into cutting-edge science and a revelatory examination of what it means to be human.

    Soon enough, she is happily ensconced in the daily workings of his family. And not only that: Stella is treated like a family member—in ways that dogs of his youth were not. Spending humanlike sums on vet bills, questioning her diet and exercise regimens, contemplating her happiness—how had this all come to pass, when the dogs from Homans’s childhood seemed quite content living mostly out in the yard?In What’s a Dog For?, Homans explores the dog’s complex and prominent place in our world and how it came to be. Evolving from wild animals to working animals to nearly human members of our social fabric, dogs are now the subject of serious scientific studies concerning pet ownership, evolutionary theory, and even cognitive science. From new insights into what makes dogs so appealing to humans to the health benefits associated with owning a dog, Homans investigates why the human-canine relationship has evolved so rapidly—how dogs moved into our families, our homes, and sometimes even our beds in the span of a generation, becoming a $53 billion industry in the United States in the process.As dogs take their place as coddled family members and their numbers balloon to more than seventy-seven million in the United States alone, it’s no surprise that canine culture at large is also undergoing a massive transformation. They are now subject to many of the same questions of rights and ethics as people, and the politics of dogs are more tumultuous and public than ever— with fierce moral battles raging over kill shelters, puppy mills, and breed standards. Incorporating interviews and research from scientists, activists, breeders, and trainers, What’s a Dog For? investigates how dogs have reached this exalted status and why they hold such fascination for us. With one paw in the animal world and one paw in the human world, it turns out they have much to teach us about love, death, and morality—and ultimately, in their closeness and difference, about what it means to be human.

    But we long to know more: how did these animals actually behave? We are fascinated by the daily lives of our fellow creatures--how they reproduce and raise their young, how they hunt their prey or elude their predators, and more. What would it be like to see prehistoric animals as they lived and breathed?From dinosaurs fighting to their deaths to elephant-sized burrowing ground sloths, this book takes readers on a global journey deep into the earth's past. Locked in Time showcases fifty of the most astonishing fossils ever found, brought together in five fascinating chapters that offer an unprecedented glimpse at the real-life behaviors of prehistoric animals. Dean R. Lomax examines the extraordinary direct evidence of fossils captured in the midst of everyday action, such as dinosaurs sitting on their eggs like birds, Jurassic flies preserved while mating, a T. rex infected by parasites. Each fossil, he reveals, tells a unique story about prehistoric life. Many recall behaviors typical of animals familiar to us today, evoking the chain of evolution that links all living things to their distant ancestors. Locked in Time allows us to see that fossils are not just inanimate objects: they can record the life stories of creatures as fully alive as any today. Striking and scientifically rigorous illustrations by renowned paleoartist Bob Nicholls bring these breathtaking moments to life.

    They force us to confront a fundamental biological problem: how can something as large and complex as a human body organize itself from the simplicity of a fertilized egg? A convergence of ideas from embryology, genetics, physics, networks, and control theory has begun to provide real answers. Based on the central principle of 'adaptive self-organization, ' it explains how the interactions of many cells, and of the tiny molecular machines that run them, can organize tissue structures vastly larger than themselves, correcting errors as they go along and creating new layers of complexity where there were none before.Life Unfolding tells the story of human development from egg to adult, from this perspective, showing how our whole understanding of how we come to be has been transformed in recent years. Highlighting how embryological knowledge is being used to understand why bodies age and fail, Jamie A. Daviesexplores the profound and fascinating impacts of our newfound knowledge.

    Tameness is the key trait in the domestication of cats, dogs, horses, cows, and other mammals, from rats to reindeer. Surprisingly, with selection for tameness comes a suite of seemingly unrelated alterations, including floppy ears, skeletal and coloration changes, and sex differences. It’s a package deal known as the domestication syndrome, elements of which are also found in humans. Our highly social nature—one of the keys to our evolutionary success—is due to our own tameness. In Domesticated, Richard C. Francis weaves history and anthropology with cutting-edge ideas in genomics and evo devo to tell the story of how we domesticated the world, and ourselves in the process.

    Drawing upon new research into cat genetics, brain chemistry, evolution, social behavior, and interaction with humans and fellow felines, acclaimed author and scientist Stephen Budiansky explores the mysteries of these amazing creatures. Wide-ranging, lively, and engaging, The Character of Cats also covers the full spectrum of feline fact and lore, from history, superstition, and religious imagery to hunting patterns, sexual behavior, and preferred colors. This smart, wonderfully readable book finally gives cats their due.