The case would become one of the most famous in modern medicine—and a total failure. As Nature Made Him tells the extraordinary story of David Reimer, who, when finally informed of his medical history, made the decision to live as a male. A macabre tale of medical arrogance, it is first and foremost a human drama of one man's—and one family's—amazing survival in the face of terrible odds.

    After acquiring Brenin as a cub, it quickly became apparent that Brenin was never to be left alone, as the consequences to Mark’s house and its contents were dire. As a result, Brenin and Mark went everywhere together—from classroom lecture to Ireland, England, and France. More than just an exotic pet, Brenin exerted an immense influence on Rowlands as both a person, and, strangely enough, as a philosopher, leading him to re-evaluate his attitude to love, happiness, nature and death. By turns funny (what do you do when your wolf eats your air-conditioning unit?) and poignant, this life-affirming book will make you reappraise what it means to be human.

    Her deep empathy and understanding, her years of observing Kenya’s rich variety of wildlife, and her pioneering work in perfecting the right husbandry and milk formula have saved countless elephants, rhinos, and other baby animals from certain death. In this heartwarming and poignant memoir, Daphne shares her amazing relationships with a host of orphans, including her first love, Bushy, a liquid-eyed antelope; Rickey-Tickey-Tavey, the little dwarf mongoose; Gregory Peck, the busy buffalo weaver bird; Huppety, the mischievous zebra; and the majestic elephant Eleanor, with whom Daphne has shared more than forty years of great friendship.  But this is also a magical and heartbreaking human love story between Daphne and David Sheldrick, the famous Tsavo Park warden. It was their deep and passionate love, David’s extraordinary insight into all aspects of nature, and the tragedy of his early death that inspired Daphne’s vast array of achievements, most notably the founding of the world-renowned David Sheldrick Wildlife Trust and the Orphans’ Nursery in Nairobi National Park, where Daphne continues to live and work to this day.  Encompassing not only David and Daphne’s tireless campaign for an end to poaching and for conserving Kenya’s wildlife, but also their ability to engage with the human side of animals and their rearing of the orphans expressly so they can return to the wild, Love, Life, and Elephants is alive with compassion and humor, providing a rare insight into the life of one of the world’s most remarkable women.

    Lisa Sanders, author of the monthly New York Times Magazine column "Diagnosis," the inspiration for the hit Fox TV series House, M.D.The experience of being ill can be like waking up in a foreign country. Life, as you formerly knew it, is on hold while you travel through this other world as unknown as it is unexpected. When I see patients in the hospital or in my office who are suddenly, surprisingly ill, what they really want to know is, ‘What is wrong with me?’ They want a road map that will help them manage their new surroundings. The ability to give this unnerving and unfamiliar place a name, to know it–on some level–restores a measure of control, independent of whether or not that diagnosis comes attached to a cure. Because, even today, a diagnosis is frequently all a good doctor has to offer.A healthy young man suddenly loses his memory–making him unable to remember the events of each passing hour. Two patients diagnosed with Lyme disease improve after antibiotic treatment–only to have their symptoms mysteriously return. A young woman lies dying in the ICU–bleeding, jaundiced, incoherent–and none of her doctors know what is killing her. In Every Patient Tells a Story, Dr. Lisa Sanders takes us bedside to witness the process of solving these and other diagnostic dilemmas, providing a firsthand account of the expertise and intuition that lead a doctor to make the right diagnosis.Never in human history have doctors had the knowledge, the tools, and the skills that they have today to diagnose illness and disease. And yet mistakes are made, diagnoses missed, symptoms or tests misunderstood. In this high-tech world of modern medicine, Sanders shows us that knowledge, while essential, is not sufficient to unravel the complexities of illness. She presents an unflinching look inside the detective story that marks nearly every illness–the diagnosis–revealing the combination of uncertainty and intrigue that doctors face when confronting patients who are sick or dying. Through dramatic stories of patients with baffling symptoms, Sanders portrays the absolute necessity and surprising difficulties of getting the patient’s story, the challenges of the physical exam, the pitfalls of doctor-to-doctor communication, the vagaries of tests, and the near calamity of diagnostic errors. In Every Patient Tells a Story, Dr. Sanders chronicles the real-life drama of doctors solving these difficult medical mysteries that not only illustrate the art and science of diagnosis, but often save the patients’ lives.

    With a career that began in the late 1950s, Joan kept mementos over the course of her entire working life, and Joan Rivers Confidential is a compilation of never-before-seen personal archives. Assembled by her daughter Melissa with Scott Currie, the book contains scripts and monologues, letters from famous friends, exchanges with fans, rare photographs, as well as classic and never-before-heard jokes—many simply scribbled on everything from hotel stationery to airplane boarding passes. Touching on subjects from her 50 years in show business (The Tonight Show, Las Vegas, Elizabeth Taylor, Heidi Abromowitz, the red carpet, and Fashion Police), this is a revelatory and humor-filled insider look at the popular, multitalented comedian.

    But when a new admission to the critical care unit almost died his first night on call, he found himself scrambling. Visions of mastery quickly gave way to hopes of simply surviving hospital life, where confidence was hard to come by and no amount of med school training could dispel the terror of facing actual patients.This funny, candid memoir of McCarthy’s intern year at a New York hospital provides a scorchingly frank look at how doctors are made, taking readers into patients’ rooms and doctors’ conferences to witness a physician's journey from ineptitude to competence. McCarthy's one stroke of luck paired him with a brilliant second-year adviser he called “Baio” (owing to his resemblance to the Charles in Charge star), who proved to be a remarkable teacher with a wicked sense of humor. McCarthy would learn even more from the people he cared for, including a man named Benny, who was living in the hospital for months at a time awaiting a heart transplant. But no teacher could help McCarthy when an accident put his own health at risk, and showed him all too painfully the thin line between doctor and patient.The Real Doctor Will See You Shortly offers a window on to hospital life that dispenses with sanctimony and self-seriousness while emphasizing the black-comic paradox of becoming a doctor: How do you learn to save lives in a job where there is no practice?

    When a small vial arrives in her mailbox from "Lewis Carroll," Ayelet Waldman is at a low point. Her mood storms have become intolerably severe; she has tried nearly every medication possible; her husband and children are suffering with her. So she opens the vial, places two drops on her tongue, and joins the ranks of an underground but increasingly vocal group of scientists and civilians successfully using therapeutic microdoses of LSD. As Waldman charts her experience over the course of a month--bursts of productivity, sleepless nights, a newfound sense of equanimity--she also explores the history and mythology of LSD, the cutting-edge research into the drug, and the byzantine policies that control it. Drawing on her experience as a federal public defender, and as the mother of teenagers, and her research into the therapeutic value of psychedelics, Waldman has produced a book that is eye-opening, often hilarious, and utterly enthralling.

    After World War II, Don's work with the Air Force brought them to Colorado, where their twelve children perfectly spanned the baby boom: the oldest born in 1945, the youngest in 1965. In those years, there was an established script for a family like the Galvins—aspiration, hard work, upward mobility, domestic harmony—and they worked hard to play their parts. But behind the scenes was a different story: psychological breakdown, sudden shocking violence, hidden abuse. By the mid-1970s, six of the ten Galvin boys, one after another, were diagnosed as schizophrenic. How could all this happen to one family?What took place inside the house on Hidden Valley Road was so extraordinary that the Galvins became one of the first families to be studied by the National Institute of Mental Health. Their story offers a shadow history of the science of schizophrenia, from the era of institutionalization, lobotomy, and the schizophrenogenic mother to the search for genetic markers for the disease, always amid profound disagreements about the nature of the illness itself. And unbeknownst to the Galvins, samples of their DNA informed decades of genetic research that continues today, offering paths to treatment, prediction, and even eradication of the disease for future generations.With clarity and compassion, bestselling and award-winning author Robert Kolker uncovers one family's unforgettable legacy of suffering, love, and hope.

    Filled with adventures of heroic dogs, lovable and lazy dogs, malodorous dogs, phlegmatic and incontinent dogs, What the Dog Did delivers some of the most outlandish and certainly the funniest dog stories on record.

    Spirited and determined, Anna quickly finds her feet and falls in love with rural life, including Ebbourne’s eccentric characters and their animals. Disasters, dramas, farmers and friendship – and not to mention a whirlwind romance with a local Wildlife Trust worker – this warm and witty memoir offers a window into what working with animals and country life is really all about.

    Judy Melinek began her training as a New York City forensic pathologist. With her husband T.J. and their toddler Daniel holding down the home front, Judy threw herself into the fascinating world of death investigation, performing autopsies, investigating death scenes, counseling grieving relatives. Working Stiff chronicles Judy's two years of training, taking readers behind the police tape of some of the most harrowing deaths in the Big Apple, including a firsthand account of the events of September 11, the subsequent anthrax bio-terrorism attack, and the disastrous crash of American Airlines flight 587.Lively, action-packed, and loaded with mordant wit, Working Stiff offers a firsthand account of daily life in one of America's most arduous professions, and the unexpected challenges of shuttling between the domains of the living and the dead. The body never lies, and through the murders, accidents, and suicides that land on her table, Dr. Melinek lays bare the truth behind the glamorized depictions of autopsy work on shows like CSI and Law and Order to reveal the secret story of the real morgue.

    A prize-winning, successful novelist in her 30s, McCracken was happy to be an itinerant writer and self-proclaimed spinster. But suddenly she fell in love, got married, and two years ago was living in a remote part of France, working on her novel, and waiting for the birth of her first child.This book is about what happened next. In her ninth month of pregnancy, she learned that her baby boy had died. How do you deal with and recover from this kind of loss? Of course you don't--but you go on. And if you have ever experienced loss or love someone who has, the company of this remarkable book will help you go on.

    Only a few weeks old, on the coldest night of the year, he was stuffed into the returned book slot at the Spencer Public Library. He was found the next working by library director Vicki Myron, a single mother who had survived the loss of her family farm, a breast cancer scare, and an alcoholic husband. Dewey won her heart, and the hearts of the staff, by pulling himself up and hobbling on frostbitten feet to nudge each of hem in a gesture of thanks and love. For the next nineteen years, he never stopped charming the people of Spencer with this enthusiasm, warmth, humility (for a cat), and, above all, his sixth sense about who needed him most.As his fame grew from town to town, then state to state, and finally, amazingly, worldwide, Dewey became more than just a friend; he became a source of pride for an extraordinary Heartland farming town pulling its way slowly back from the greatest crisis in its long history.

    Though the world at first recoiled at the notion of a woman studying medicine, her intelligence and intensity ultimately won her the acceptance of the male medical establishment. In 1849, she became the first woman in America to receive an M.D. She was soon joined in her iconic achievement by her younger sister, Emily, who was actually the more brilliant physician.Exploring the sisters’ allies, enemies, and enduring partnership, Janice P. Nimura presents a story of trial and triumph. Together, the Blackwells founded the New York Infirmary for Indigent Women and Children, the first hospital staffed entirely by women. Both sisters were tenacious and visionary, but their convictions did not always align with the emergence of women’s rights—or with each other. From Bristol, Paris, and Edinburgh to the rising cities of antebellum America, this richly researched new biography celebrates two complicated pioneers who exploded the limits of possibility for women in medicine. As Elizabeth herself predicted, "a hundred years hence, women will not be what they are now."

    Today, it is the most common form of officially classified mental illness. Scott Stossel gracefully guides us across the terrain of an affliction that is pervasive yet too often misunderstood. Drawing on his own long-standing battle with anxiety, Stossel presents an astonishing history, at once intimate and authoritative, of the efforts to understand the condition from medical, cultural, philosophical, and experiential perspectives. He ranges from the earliest medical reports of Galen and Hippocrates, through later observations by Robert Burton and Søren Kierkegaard, to the investigations by great nineteenth-century scientists, such as Charles Darwin, William James, and Sigmund Freud, as they began to explore its sources and causes, to the latest research by neuroscientists and geneticists. Stossel reports on famous individuals who struggled with anxiety, as well as on the afflicted generations of his own family. His portrait of anxiety reveals not only the emotion’s myriad manifestations and the anguish anxiety produces but also the countless psychotherapies, medications, and other (often outlandish) treatments that have been developed to counteract it. Stossel vividly depicts anxiety’s human toll—its crippling impact, its devastating power to paralyze—while at the same time exploring how those who suffer from it find ways to manage and control it. My Age of Anxiety is learned and empathetic, humorous and inspirational, offering the reader great insight into the biological, cultural, and environmental factors that contribute to the affliction.