Virolution


Frank Ryan - 2009
    His explanation of the role of natural selection in driving the evolution of life on earth depended on steady variation of living things over time – but he was unable to explain how this variation occurred. In the 150 years since publication of the Origin of Species, we have discovered three main sources for this variation – mutation, hybridisation and epigenetics. Then on Sunday, 12th February, 2001 the evidence for perhaps the most extraordinary cause of variation was simultaneously released by two organisations – the code for the entire human genome. Not only was the human genome unbelievably simple (it is only ten times more complicated than a bacteria), but embedded in the code were large fragments that were derived from viruses – fragments that were vital to evolution of all organisms and the evidence for a fourth and vital source of variation – viruses.Virolution was the subject of a feature article in New Scientist. Translated into Russian, French, German and Japanese, this book has become a hot topic for discussion among scientists and thinkers in recent years. It offers a very new interpretation of our human evolution - and extrapolates to new avenues of approach to fight important diseases, such as cancer and MS.In early 2014 Dr Ryan has co-authored a relevant new paper with Swedish and Chinese scientists working on the Human Proteome project. More details about this paper and other developments will follow in his articles and blogs. So popular is the topic he has been commissioned to give a plenary lecture followed by planning and research advice to PhD students in biology and evolutionary biology at the annual European Society for Evolutionary Biology annual meeting for PhD students in Belgium in September 2014.More anon...

Why Darwin Matters: The Case Against Intelligent Design


Michael Shermer - 2006
    Half of Americans reject the theory of evolution and "Intelligent Design" campaigns are gaining ground. Classroom by classroom, creationism is overthrowing biology.In Why Darwin Matters, bestselling author Michael Shermer explains how the newest brand of creationism appeals to our predisposition to look for a designer behind life's complexity. Shermer decodes the scientific evidence to show that evolution is not "just a theory" and illustrates how it achieves the design of life through the bottom-up process of natural selection. Shermer, once an evangelical Christian and a creationist, argues that Intelligent Design proponents are invoking a combination of bad science, political antipathy, and flawed theology. He refutes their pseudoscientific arguments and then demonstrates why conservatives and people of faith can and should embrace evolution. He then appraises the evolutionary questions that truly need to be settled, building a powerful argument for science itself.Cutting the politics away from the facts, Why Darwin Matters is an incisive examination of what is at stake in the debate over evolution.

Gaia: A New Look at Life on Earth


James E. Lovelock - 1979
    Written for the non-scientist, Gaia is a journey through time and space in search of evidence with which to support a new and radically different model of our planet. In contrast to conventional belief that living matter is passive in the face of threats to its existence, the book explores the hypothesis that the earth's living matter-air, ocean, and land surfaces-forms a complex system that has the capacity to keep the Earth a fit place for life. Since Gaia was first published, many of Jim Lovelock's predictions have come true, and his theory has become a hotly argued topic in scientific circles. Here, in a new Preface, Lovelock outlines his present state of the debate.

The Antidote: A Small Competitor Challenges the Drug Giants: Conquests in New Pharma


Barry Werth - 2014
    

Rosalind Franklin: The Dark Lady of DNA


Brenda Maddox - 2002
    Brenda Maddox tells a powerful story of a remarkably single-minded, forthright, and tempestuous young woman who, at the age of fifteen, decided she was going to be a scientist, but who was airbrushed out of the greatest scientific discovery of the twentieth century.

Evolution for Everyone: How Darwin's Theory Can Change the Way We Think About Our Lives


David Sloan Wilson - 2007
    With stories that entertain as much as they inform, Wilson outlines the basic principles of evolution and shows how, properly understood, they can illuminate the length and breadth of creation, from the origin of life to the nature of religion. Now everyone can move beyond the sterile debates about creationism and intelligent design to share Darwin’s panoramic view of animal and human life, seamlessly connected to each other.Evolution, as Wilson explains, is not just about dinosaurs and human origins, but about why all species behave as they do—from beetles that devour their own young, to bees that function as a collective brain, to dogs that are smarter in some respects than our closest ape relatives. And basic evolutionary principles are also the foundation for humanity’s capacity for symbolic thought, culture, and morality.In example after example, Wilson sheds new light on Darwin’s grand theory and how it can be applied to daily life. By turns thoughtful, provocative, and daringly funny, Evolution for Everyone addresses some of the deepest philosophical and social issues of this or any age. In helping us come to a deeper understanding of human beings and our place in the world, it might also help us to improve that world.

Germs, Genes, & Civilization: How Epidemics Shaped Who We Are Today


David P. Clark - 2004
    No one can stop him--but he walks away. A miracle? No...dysentery. Microbes saved the Roman Empire. Nearly a millennium later, the microbes of the Black Death ended the Middle Ages, making possible the Renaissance, western democracy, and the scientific revolution. Soon after, microbes ravaged the Americas, paving the way for their European conquest. Again and again, microbes have shaped our health, our genetics, our history, our culture, our politics, even our religion and ethics. This book reveals much that scientists and cultural historians have learned about the pervasive interconnections between infectious microbes and humans. It also considers what our ongoing fundamental relationship with infectious microbes might mean for the future of the human species. The "good side" of history's worst epidemics The surprising debt we owe to killer diseases Where diseases came from... ...and where they may be going Children of pestilence: disease and civilization From Egypt to Mexico, the Romans to Attila the Hun STDs, sexual behavior, and culture How microbes may shape cultural cycles of puritanism and promiscuity

The Idea of the Brain: The Past and Future of Neuroscience


Matthew Cobb - 2020
    Yet, despite the astonishing discoveries of science, we still have only the vaguest idea of how the brain works. In The Idea of the Brain, scientist and historian Matthew Cobb traces how our conception of the brain has evolved over the centuries. Although it might seem to be a story of ever-increasing knowledge of biology, Cobb shows how our ideas about the brain have been shaped by each era's most significant technologies. Today we might think the brain is like a supercomputer. In the past, it has been compared to a telegraph, a telephone exchange, or some kind of hydraulic system. What will we think the brain is like tomorrow, when new technology arises? The result is an essential read for anyone interested in the complex processes that drive science and the forces that have shaped our marvelous brains.

Structures: Or Why Things Don't Fall Down


J.E. Gordon - 1978
    Gordon strips engineering of its confusing technical terms, communicating its founding principles in accessible, witty prose.For anyone who has ever wondered why suspension bridges don't collapse under eight lanes of traffic, how dams hold back--or give way under--thousands of gallons of water, or what principles guide the design of a skyscraper, a bias-cut dress, or a kangaroo, this book will ease your anxiety and answer your questions.Structures: Or Why Things Don't Fall Down is an informal explanation of the basic forces that hold together the ordinary and essential things of this world--from buildings and bodies to flying aircraft and eggshells. In a style that combines wit, a masterful command of his subject, and an encyclopedic range of reference, Gordon includes such chapters as "How to Design a Worm" and "The Advantage of Being a Beam," offering humorous insights in human and natural creation.Architects and engineers will appreciate the clear and cogent explanations of the concepts of stress, shear, torsion, fracture, and compression. If you're building a house, a sailboat, or a catapult, here is a handy tool for understanding the mechanics of joinery, floors, ceilings, hulls, masts--or flying buttresses.Without jargon or oversimplification, Structures opens up the marvels of technology to anyone interested in the foundations of our everyday lives.

Editing Humanity: The CRISPR Revolution and the New Era of Genome Editing


Kevin Davies - 2020
    For decades, these questions have lived exclusively in the realm of science fiction, but as Kevin Davies powerfully reveals in his new book, this is all about to change.Engrossing and page-turning, Editing Humanity takes readers inside the fascinating world of a new gene editing technology called CRISPR, a high-powered genetic toolkit that enables scientists to not only engineer but to edit the DNA of any organism down to the individual building blocks of the genetic code.Davies introduces readers to arguably the most profound scientific breakthrough of our time. He tracks the scientists on the front lines of its research to the patients whose powerful stories bring the narrative movingly to human scale.Though the birth of the “CRISPR babies” in China made international news, there is much more to the story of CRISPR than headlines seemingly ripped from science fiction. In Editing Humanity, Davies sheds light on the implications that this new technology can have on our everyday lives and in the lives of generations to come.

Good Germs, Bad Germs: Health and Survival in a Bacterial World


Jessica Snyder Sachs - 2007
    As a result, antibiotic resistance now ranks among the gravest medical problems of modern times. Good Germs, Bad Germs addresses not only this issue but also what has become known as the "hygiene hypothesis"-- an argument that links the over-sanitation of modern life to now-epidemic increases in immune and other disorders. In telling the story of what went terribly wrong in our war on germs, Jessica Snyder Sachs explores our emerging understanding of the symbiotic relationship between the human body and its resident microbes--which outnumber its human cells by a factor of nine to one! The book also offers a hopeful look into a future in which antibiotics will be designed and used more wisely, and beyond that, to a day when we may replace antibacterial drugs and cleansers with bacterial ones--each custom-designed for maximum health benefits.

Rare Earth: Why Complex Life Is Uncommon in the Universe


Peter D. Ward - 2000
    In doing so, the authors synthesize information from astronomy, biology, and paleontology, and apply it to what we know about the rise of life on Earth and to what could possibly happen elsewhere in the universe. Everyone who has been thrilled by the recent discoveries of extrasolar planets and the indications of life on Mars and the Jovian moon Europa will be fascinated by Rare Earth, and its implications for those who look to the heavens for companionship.

Idiot Brain: What Your Head Is Really Up To


Dean Burnett - 2016
    But it’s also messy, fallible, and about 50,000 years out of date. We cling to superstitions, remember faces but not names, miss things sitting right in front of us, and lie awake at night while our brains endlessly replay our greatest fears. Idiot Brain is for anyone who has ever wondered why their brain appears to be sabotaging their life—and what on earth it is really up to.A Library Journal Science Bestseller and a Finalist for the Goodreads Choice Award in Science Technology.

The Water Will Come: Rising Seas, Sinking Cities, and the Remaking of the Civilized World


Jeff Goodell - 2017
    With each crack in the great ice sheets of the Arctic and Antarctica, and each tick upwards of Earth's thermometer, we are moving closer to the brink of broad disaster.By century's end, hundreds of millions of people will be retreating from the world's shores as our coasts become inundated and our landscapes transformed. From island nations to the world's major cities, coastal regions will disappear. Engineering projects to hold back the water are bold and may buy some time. Yet despite international efforts and tireless research, there is no permanent solution--no barriers to erect or walls to build--that will protect us in the end from the drowning of the world as we know it.The Water Will Come is the definitive account of the coming water, why and how this will happen, and what it will all mean. As he travels across twelve countries and reports from the front lines, acclaimed journalist Jeff Goodell employs fact, science, and first-person, on-the-ground journalism to show vivid scenes from what already is becoming a water world.

The Telomere Effect: A Revolutionary Approach to Living Younger, Healthier, Longer


Elizabeth Blackburn - 2017
    Elizabeth Blackburn discovered a biological indicator called telomerase, the enzyme that replenishes telomeres, which protect our genetic heritage. Dr. Blackburn and Dr. Elissa Epel's research shows that the length and health of one's telomeres are a biological underpinning of the long-hypothesized mind-body connection. They and other scientists have found that changes we can make to our daily habits can protect our telomeres and increase our health spans (the number of years we remain healthy, active, and disease-free).THE TELOMERE EFFECT reveals how Blackburn and Epel's findings, together with research from colleagues around the world, cumulatively show that sleep quality, exercise, aspects of diet, and even certain chemicals profoundly affect our telomeres, and that chronic stress, negative thoughts, strained relationships, and even the wrong neighborhoods can eat away at them. Drawing from this scientific body of knowledge, they share lists of foods and suggest amounts and types of exercise that are healthy for our telomeres, mind tricks you can use to protect yourself from stress, and information about how to protect your children against developing shorter telomeres, from pregnancy through adolescence. And they describe how we can improve our health spans at the community level, with neighborhoods characterized by trust, green spaces, and safe streets. THE TELOMERE EFFECT will make you reassess how you live your life on a day-to-day basis. It is the first book to explain how we age at a cellular level and how we can make simple changes to keep our chromosomes and cells healthy, allowing us to stay disease-free longer and live more vital and meaningful lives.