Reginald Bray (1879-1939) was one of an ordinary middle-class Englishman quietly living out his time as an accountant in the leafy suburb of Forest Hill, London. A glimpse behind his study door, however, revealed his extraordinary passion for sending unusual items through the mail. In 1898, Bray purchased a copy of the Post Office Guide, and began to study the regulations published quarterly by the British postal authorities. He discovered that the smallest item one could post was a bee, and the largest, an elephant. Intrigued,he decided to experiment with sending ordinary and strange objects through the post unwrapped, including a turnip, abowler hat, a bicycle pump, shirt cuffs, seaweed, a clothes brush, even a rabbit's skull. He eventually posted his Irish terrier and himself (not together), earning him the name "The Human Letter." He also mailed cards to challenging addressessome in the form of picture puzzles, others sent to ambiguous recipients at hard to reach destinationsall in the name of testing the deductive powers of the beleaguered postman. Over time hispassion changed from sending curios to amassing the world's largest collection of autographs, also via the post. Starting with key British military officers involved in the Second Boer War, he acquired thousands of autographs during the first four decades of the twentieth centuryof politicians, military men, performing artists, aviators, sporting stars, and many others. By the time he died in 1939, Bray had sent out more than thirty-two thousand postal curios and autograph requests. The Englishman Who Posted Himself and Other Curious Objects tells W. Reginald Bray's remarkable tale for the first time and includes delightful illustrations of some of his most amazing postal creations. Readers will never look at the objects they post the same way again.

    Days later, the madman was dead and Denis was framed for murder. A riveting exposé of the fierce debates, deadly politics, and cutthroat rivalries behind the first transfusion experiments, Blood Work takes us from dissection rooms in palaces to the streets of Paris, providing an unforgettable portrait of an era that wrestled with the same questions about morality and experimentation that haunt medical science today.

    Lewellyn Powys called it "the greatest work of prose of the greatest period of English prose-writing," while the celebrated surgeon William Osler declared it the greatest of medical treatises. And Dr. Johnson, Boswell reports, said it was the only book that he rose early in the morning to read with pleasure. In this surprisingly compact and elegant new edition, Burton's spectacular verbal labyrinth is sure to delight, instruct, and divert today's readers as much as it has those of the past four centuries.

    Physician, researcher, and award-winning science writer, Siddhartha Mukherjee examines cancer with a cellular biologist’s precision, a historian’s perspective, and a biographer’s passion. The result is an astonishingly lucid and eloquent chronicle of a disease humans have lived with - and perished from - for more than five thousand years. The story of cancer is a story of human ingenuity, resilience, and perseverance, but also of hubris, paternalism, and misperception. Mukherjee recounts centuries of discoveries, setbacks, victories, and deaths, told through the eyes of his predecessors and peers, training their wits against an infinitely resourceful adversary that, just three decades ago, was thought to be easily vanquished in an all-out “war against cancer.” The book reads like a literary thriller with cancer as the protagonist. From the Persian Queen Atossa, whose Greek slave cut off her malignant breast, to the nineteenth-century recipients of primitive radiation and chemotherapy to Mukherjee’s own leukemia patient, Carla, The Emperor of All Maladies is about the people who have soldiered through fiercely demanding regimens in order to survive—and to increase our understanding of this iconic disease. Riveting, urgent, and surprising, The Emperor of All Maladies provides a fascinating glimpse into the future of cancer treatments. It is an illuminating book that provides hope and clarity to those seeking to demystify cancer.

    For centuries, royal families have feared the gut-roiling, vomit-inducing agony of a little something added to their food or wine by an enemy. To avoid poison, they depended on tasters, unicorn horns, and antidotes tested on condemned prisoners. Servants licked the royal family’s spoons, tried on their underpants and tested their chamber pots.Ironically, royals terrified of poison were unknowingly poisoning themselves daily with their cosmetics, medications, and filthy living conditions. Women wore makeup made with mercury and lead. Men rubbed turds on their bald spots. Physicians prescribed mercury enemas, arsenic skin cream, drinks of lead filings, and potions of human fat and skull, fresh from the executioner. The most gorgeous palaces were little better than filthy latrines. Gazing at gorgeous portraits of centuries past, we don’t see what lies beneath the royal robes and the stench of unwashed bodies; the lice feasting on private parts; and worms nesting in the intestines.In The Royal Art of Poison, Eleanor Herman combines her unique access to royal archives with cutting-edge forensic discoveries to tell the true story of Europe’s glittering palaces: one of medical bafflement, poisonous cosmetics, ever-present excrement, festering natural illness, and, sometimes, murder.

    We like to imagine that it’s based on evidence and the results of fair tests. In reality, those tests are often profoundly flawed. We like to imagine that doctors are familiar with the research literature surrounding a drug, when in reality much of the research is hidden from them by drug companies. We like to imagine that doctors are impartially educated, when in reality much of their education is funded by industry. We like to imagine that regulators let only effective drugs onto the market, when in reality they approve hopeless drugs, with data on side effects casually withheld from doctors and patients.All these problems have been protected from public scrutiny because they’re too complex to capture in a sound bite. But Dr. Ben Goldacre shows that the true scale of this murderous disaster fully reveals itself only when the details are untangled. He believes we should all be able to understand precisely how data manipulation works and how research misconduct on a global scale affects us. In his own words, “the tricks and distortions documented in these pages are beautiful, intricate, and fascinating in their details.” With Goldacre’s characteristic flair and a forensic attention to detail, Bad Pharma reveals a shockingly broken system and calls for something to be done. This is the pharmaceutical industry as it has never been seen before.

    As well as recording public and historical events, Pepys paints a vivid picture of his personal life, from his socializing and amorous entanglements, to his theatre-going and his work at the Navy Board. Unequaled for its frankness, high spirits and sharp observations, the diary is both a literary masterpiece and a marvelous portrait of seventeenth-century life.Previously published as The Shorter Pepys, this edition is edited and abridged by Robert Latham, Fellow and Pepys Librarian at Magdalene College, Cambridge.

    Such vivid and exciting personal accounts add greatly to the unique qualities of this work.The translation and notes by A.E. Waite are immaculate. Waite was a noted occult scholar of his day, teaching in both the Hermetic and Rosicrucian orders. Due to the high calibre of both author and editor, this book maintains its pre-eminent position in the literature of the magic arts.

    At his death last spring, Roueche left behind seven new narratives that have never been published in book form. This book collects these works along with one earlier classic--all relating true tales of strange illnesses, rare diseases, and the brilliant minds who race to understand and conquer them.

    Acclaimed historian G. J. Meyer reveals the flesh-and-bone reality in all its wild excess.In 1485, young Henry Tudor, whose claim to the throne was so weak as to be almost laughable, crossed the English Channel from France at the head of a ragtag little army and took the crown from the family that had ruled England for almost four hundred years. Half a century later his son, Henry VIII, desperate to rid himself of his first wife in order to marry a second, launched a reign of terror aimed at taking powers no previous monarch had even dreamed of possessing. In the process he plunged his kingdom into generations of division and disorder, creating a legacy of blood and betrayal that would blight the lives of his children and the destiny of his country.The boy king Edward VI, a fervent believer in reforming the English church, died before bringing to fruition his dream of a second English Reformation. Mary I, the disgraced daughter of Catherine of Aragon, tried and failed to reestablish the Catholic Church and produce an heir. And finally came Elizabeth I, who devoted her life to creating an image of herself as Gloriana the Virgin Queen but, behind that mask, sacrificed all chance of personal happiness in order to survive.  The Tudors weaves together all the sinners and saints, the tragedies and triumphs, the high dreams and dark crimes, that reveal the Tudor era to be, in its enthralling, notorious truth, as momentous and as fascinating as the fictions audiences have come to love.

    A meld of history and science, this book is a group portrait of some of the greatest minds who ever lived as they wrestled with nature’s most sweeping mysteries. The answers they uncovered still hold the key to how we understand the world.At the end of the seventeenth century—an age of religious wars, plague, and the Great Fire of London—when most people saw the world as falling apart, these earliest scientists saw a world of perfect order. They declared that, chaotic as it looked, the universe was in fact as intricate and perfectly regulated as a clock. This was the tail end of Shakespeare’s century, when the natural land the supernatural still twined around each other. Disease was a punishment ordained by God, astronomy had not yet broken free from astrology, and the sky was filled with omens. It was a time when little was known and everything was new. These brilliant, ambitious, curious men believed in angels, alchemy, and the devil, and they also believed that the universe followed precise, mathematical laws—-a contradiction that tormented them and changed the course of history.The Clockwork Universe is the fascinating and compelling story of the bewildered geniuses of the Royal Society, the men who made the modern world.

    Like magic, her terminal cancer just melted away. In this truly ground-breaking book, Jane takes us through her remarkable, heart-breaking journey, and the medical discoveries she made on the way. Using herself as a human guinea pig, she worked out the best drugs and supplements to starve her own cancer in an easy-to-follow ‘Metro Map’. She has expanded this route map to show which fuel pipelines you need to block for every type of cancer, so you too can create your own cancer-starving cocktail. Tragically many simple old drugs have been overlooked in the race for the latest patentable 'game changers’. Is the answer already out there? Jane believes it is. Bit by bit she has pieced the puzzle together, demystified its complexity, and produced a simple protocol. This book will answer all the burning questions you face when you begin to explore complementary cancer care. Which ‘off-label’ drugs and supplements should you take? Should you try the ketogenic diet? Should you fast? Is fat safe? How much and when should you exercise? Jane explains why each patient needs a personalised approach and, importantly, how to work this out. This book, part Erin Brockovich, part Dallas Buyers Club, is a compelling story of resilience and determination in the face of impossible odds. If you or a loved one has cancer, you absolutely must read this book. Even if you have been told that nothing more can be done, Jane will show you this is almost certainly not true. “So powerful and relatable. Often in medical books the science overwhelms and dilutes the narrative arc but because of Jane's compelling and dramatic personal story the book promises to hold the reader. Beyond the personal narrative, the strategy Jane used to get well is at the very forefront in the war against cancer. The use of re-purposed drugs in oncology is gaining traction worldwide. Additionally, and perhaps most importantly, is Jane herself. We were both speakers at a recent charity event in London. Jane spoke last, and when she finished, I'm not sure there was a dry eye in the room. She received the only standing ovation at the event. Her story is so powerful; tragic yet triumphant, and relatable to anyone who has had a foot in the realm of the sick. Jane is a fantastic speaker. She has the rare gift of being entirely genuine. Her story: of a terminal diagnosis in the prime of her life, self-discovery, and path to wellness driven by her own conviction and research has the ability to inspire hope and wake the medical community up to a powerful new tool; the use of combinations of repurposed drugs.” Travis Christofferson, author Tripping Over the Truth “All patients and their relatives need to read this book.” Professor Justin Stebbing, Professor of Cancer Medicine and Oncology at Imperial College "Jane’s clinical reasoning is impressive, her experience is compelling and in the combination of these two elements she has crafted a narrative that, like the anti-cancer metabolic cocktail she champions, is destined to positively enhance countless lives.” Dr Ndaba Mazibuko, Clinical Research Fellow, King's College London Care Oncology Clinic “Jane’s story will inspire anyone reeling from the shock of a cancer diagnosis to take control of their own destiny.” Lois Rogers, freelance health journalist, Sunday Times

    Night Falls Fast is tragically timely: suicide has become one of the most common killers of Americans between the ages of fifteen and forty-five.An internationally acknowledged authority on depressive illnesses, Dr. Jamison has also known suicide firsthand: after years of struggling with manic-depression, she tried at age twenty-eight to kill herself. Weaving together a historical and scientific exploration of the subject with personal essays on individual suicides, she brings not only her remarkable compassion and literary skill but also all of her knowledge and research to bear on this devastating problem. This is a book that helps us to understand the suicidal mind, to recognize and come to the aid of those at risk, and to comprehend the profound effects on those left behind. It is critical reading for parents, educators, and anyone wanting to understand this tragic epidemic.

    From its origins in 1738 as an almshouse and pesthouse, Bellevue today is a revered public hospital bringing first-class care to anyone in need. With its diverse, ailing, and unprotesting patient population, the hospital was a natural laboratory for the nation's first clinical research. It treated tens of thousands of Civil War soldiers, launched the first civilian ambulance corps and the first nursing school for women, pioneered medical photography and psychiatric treatment, and spurred New York City to establish the country's first official Board of Health. As medical technology advanced, "voluntary" hospitals began to seek out patients willing to pay for their care. For charity cases, it was left to Bellevue to fill the void. The latter decades of the twentieth century brought rampant crime, drug addiction, and homelessness to the nation's struggling cities problems that called a public hospital's very survival into question. It took the AIDS crisis to cement Bellevue's enduring place as New York's ultimate safety net, the iconic hospital of last resort.

    From the woman suffering from "painful foot and moving toe syndrome" to the Indiana farmer who contacted a variant of mad cow disease from his herds of livestock, Klawans deduced a great deal from his patients, not only about the immediate causes of their ailments, but about the evolutionary underpinnings of their behavior.