But if we are supposedly evolution’s greatest creation, why do we have such bad knees? Why do we catch head colds so often—two hundred times more often than a dog does? How come our wrists have so many useless bones? Why is the vast majority of our genetic code pointless? And are we really supposed to swallow and breathe through the same narrow tube? Surely there’s been some kind of mistake. As professor of biology Nathan H. Lents explains in Human Errors, our evolutionary history is nothing if not a litany of mistakes, each more entertaining and enlightening than the last. The human body is one big pile of compromises. But that is also a testament to our greatness: as Lents shows, humans have so many design flaws precisely because we are very, very good at getting around them.   A rollicking, deeply informative tour of humans’ four billion year long evolutionary saga, Human Errors both celebrates our imperfections and offers an unconventional accounting of the cost of our success.

    If we started off with rudimentary utterances on the level of "man throw spear," how did we end up with sophisticated grammars, enormous vocabularies, and intricately nuanced degrees of meaning?Drawing on recent groundbreaking discoveries in modern linguistics, Deutscher exposes the elusive forces of creation at work in human communication, giving us fresh insight into how language emerges, evolves, and decays. He traces the evolution of linguistic complexity from an early "Me Tarzan" stage to such elaborate single-word constructions as the Turkish sehirlilestiremediklerimizdensiniz ("you are one of those whom we couldn't turn into a town dweller"). Arguing that destruction and creation in language are intimately entwined, Deutscher shows how these processes are continuously in operation, generating new words, new structures, and new meanings.

    With a muckraker's passion, Whitaker argues that modern treatments for the severely mentally ill are just old medicine in new bottles, and that we as a society are deeply deluded about their efficacy. Tracing over three centuries of "cures" for madness, Whitaker shows how medical therapies have been used to silence patients and dull their minds. He tells of the eighteenth- and nineteenth-century practices of "spinning" the insane, extracting their teeth, ovaries, and intestines, and submerging patients in freezing water. The "cures" in the 1920s and 1930s were no less barbaric as eugenic attitudes toward the mentally ill led to brain-damaging lobotomies and electroshock therapy. Perhaps Whitaker's most damning revelation, however, is his report of how drug companies in the 1980s and 1990s skewed their studies in an effort to prove the effectiveness of their products. Based on exhaustive research culled from old patient medical records, historical accounts, numerous interviews, and hundreds of government documents, Mad in America raises important questions about our obligations to the mad, what it means to be "insane," and what we value most about the human mind.

    In 1789 Ben Franklin wrote, "In this world nothing is certain but death and taxes." Death remains a certainty. But how do we die? It's the enormous variety of how that enlivens final exits.According to death certificates, in 1700 there were less than 100 causes of death. Today there are 3,000. With each advance of technology, people find new ways to become deceased, often causing trends that peak in the first year. People are now killed by everything, from cell phones, washing machines, lawn mowers and toothpicks, to the boundless catalog of man—made medicines. In Final Exits the causes of death—bizarre or common—are alphabetically arranged and include actual accounts of people, both famous and ordinary, who unfortunately died that way. (Ants, bad words, Bingo, bean bag chairs, flying cows, frozen toilets, hiccups, lipstick, moray eels, road kill, starfish, and toupees are only some of the more unusual causes.)

    Intriguingly fascinating and entertaining reading for anyone who is interested in how society copes with catastrophe and pain. Relevant today in face of the worldwide medical calamity of AIDS. Continuously in print since its first publication in 1934, with over 75 printings.

    From Mary Lamb, sister of Charles, who in the throes of a nervous breakdown turned on her mother with a kitchen knife, to Freud, Jung, and Lacan, who developed the new women-centered therapies, Lisa Appignanesi’s research traces how more and more of the inner lives and emotions of women have become a matter for medics and therapists. Here too is the story of how over the years symptoms and diagnoses have developed together to create fashions in illness and how treatments have succeeded or sometimes failed. Mad, Bad, and Sad takes us on a fascinating journey through the fragile, extraordinary human mind.

    It recounts the life histories of those who had been victims of the 1920s encephalitis lethargica epidemic. Sacks chronicles his efforts in the late 1960s to help these patients at the Beth Abraham Hospital in the Bronx, New York.

    Beginning with his family’s odyssey, In a Different Key tells the extraordinary story of this often misunderstood condition, and of the civil rights battles waged by the families of those who have it. Unfolding over decades, it is a beautifully rendered history of ordinary people determined to secure a place in the world for those with autism—by liberating children from dank institutions, campaigning for their right to go to school, challenging expert opinion on what it means to have autism, and persuading society to accept those who are different.  It is the story of women like Ruth Sullivan, who rebelled against a medical establishment that blamed cold and rejecting “refrigerator mothers” for causing autism; and of fathers who pushed scientists to dig harder for treatments. Many others played starring roles too: doctors like Leo Kanner, who pioneered our understanding of autism; lawyers like Tom Gilhool, who took the families’ battle for education to the courtroom; scientists who sparred over how to treat autism; and those with autism, like Temple Grandin, Alex Plank, and Ari Ne’eman, who explained their inner worlds and championed the philosophy of neurodiversity. This is also a story of fierce controversies—from the question of whether there is truly an autism “epidemic,” and whether vaccines played a part in it; to scandals involving “facilitated communication,” one of many treatments that have proved to be blind alleys; to stark disagreements about whether scientists should pursue a cure for autism. There are dark turns too: we learn about experimenters feeding LSD to children with autism, or shocking them with electricity to change their behavior; and the authors reveal compelling evidence that Hans Asperger, discoverer of the syndrome named after him, participated in the Nazi program that consigned disabled children to death.<

    Based on selective breeding of human beings, eugenics began in laboratories on Long Island but ended in the concentration camps of Nazi Germany. Cruel and racist laws were enacted in 27 U.S. states, while the supporters of eugenics included progressive thinkers like Woodrow Wilson, Margaret Sanger and Oliver Wendell Holmes. Ultimately, over 60,000 "unfit" Americans were coercively sterilized, a third of them after Nuremberg had declared such practices crimes against humanity. This is a timely and shocking chronicle of bad science at its worst—with many important lessons for the genetic age in which an interest in eugenics has been dangerously revived.

    Lieberman illuminates how these ongoing changes have brought many benefits, but also have created novel conditions to which our bodies are not entirely adapted, resulting in a growing incidence of obesity and new but avoidable diseases, including type-2 diabetes. He proposes that many of these chronic illnesses persist and in some cases are intensifying because of "dysevolution," a pernicious dynamic whereby only the symptoms rather than the causes of these maladies are treated. And finally—provocatively—he advocates the use of evolutionary information to help nudge, push, and sometimes oblige us to create a more salubrious environment.(With charts and line drawings throughout.)From the Hardcover edition.

    In Under the Knife, surgeon Arnold Van de Laar uses his own experience and expertise to tell the witty history of the past, present and future of surgery.From the story of the desperate man from seventeenth-century Amsterdam who grimly cut a stone out of his own bladder to Bob Marley's deadly toe, Under the Knife offers all kinds of fascinating and unforgettable insights into medicine and history via the operating theatre.What happens during an operation? How does the human body respond to being attacked by a knife, a bacterium, a cancer cell or a bullet? And, as medical advances continuously push the boundaries of what medicine can cure, what are the limits of surgery?From the dark centuries of bloodletting and of amputations without anaesthetic to today's sterile, high-tech operating theatres, Under the Knife is both a rich cultural history, and a modern anatomy class for us all.

    In the midst of all this death, a bizarre disease appeared in Europe. Eventually known as encephalitis lethargica, or sleeping sickness, it would spread across the world, leaving millions dead or locked in institutions. Then, in 1927, it would disappear as suddenly as it had arrived-or so the doctors at first thought. Asleep, set in 1920s and '30s New York, follows a group of neurologists through hospitals and insane asylums as they try to solve this worldwide epidemic. The symptoms could include not only unending sleep but dangerous insomnia, facial tics, catatonia, Parkinson's, and even violent insanity. Molly Caldwell Crosby, acclaimed author of The American Plague, explores the frightening history of this forgotten disease- and details the frantic effort to conquer it before it strikes again.

    Linda Stratmann’s dark and splendid social history reveals the nineteenth century as a gruesome battleground where poisoners went head-to-head with authorities who strove to detect poisons, control their availability, and bring the guilty to justice. She corrects many misconceptions about particular poisons and documents how the evolution of issues such as marital rights and the legal protection of children impacted poisonings. Combining archival research with a novelist’s eye, Stratmann charts the era’s inexorable rise of poison cases both shocking and sad.

    It is too bad, write scientist-historian couple Robert and Michèle Root-Bernstein, who deplore the loss of proven methods developed without the blessing of the academy, noting that "formal academic systems are only one of many ways in which knowledge is discovered, accumulated, and transmitted." Many scientists are now coming to agree with this view, they write in this fascinating collection of case studies. Researchers have showed that black tea, for instance, has powerful antibiotic properties and that maggots do an extraordinary job of cleaning wounds--as traditional healers have known all along.

    We ignore this reality most of the time, but when a new threat (Ebola, SARS, Zika) seems imminent, we send our best and bravest doctors to contain it--people like Dr. Ali S. Khan.In his long career as a public health first responder—protected by a thin mask from infected patients, napping under nets to keep out scorpions, making life-and-death decisions on limited, suspect information—Khan has found that rogue microbes will always be a problem, but outbreaks are often caused by people. We make mistakes, politicize emergencies, and, too often, fail to imagine the consequences of our actions.The Next Pandemic is a firsthand account of disasters like anthrax, bird flu, and others and how we could do more to prevent their return. It's both a gripping story of our brushes with fate and an urgent lesson on how we can keep ourselves safe from the inevitable next pandemic.