In brief, it is concerned with the scientific and technological aspects of the design and manufacture of dosage forms for medicines. An understanding of pharmaceutics is therefore vital to all pharmacists and pharmaceutical scientists who are involved in converting a drug or a potential drug into a medicine that can be delivered safely, efficiently and conveniently to the patient.Professor Aulton's Pharmaceutics has become established as the clearest, most comprehensive textbook on this subject. The book provides pharmacy and pharmaceutical science students with the latest information on all aspects of pharmaceutics.provides a logical, comprehensive account of drug design and manufactureincludes the science of formulation and drug deliverydesigned and written for newcomers to the design of dosage formstwo new chapters on the principles and practice of sterilizationdosage-form design and delivery material thoroughly updatedproduct stability and stability testing of medicinal products section totally rewritten and expanded to include more of the relevant chemistryreflects current and future use of biotechnology products throughoutchanges in our understanding of biopharmaceutics, certain areas of drug delivery and the significance of the solid state all reflectednew page size and designnew photographs of equipment and apparatus

    But where should you start? Americans are slowly becoming ill from impaired glucose metabolism that manifests itself as a debilitating illness or chronic condition. You may try to manage one problem after another– diuretics to treat blood pressure, statins to lower cholesterol, metformin and insulin to treat diabetes--without fully realizing that the root of these issues is insulin resistance which revs up inflammation, damages the immune system, and disrupts the whole hormonal/chemical system in the body.It's time to feel better and get healthy by following a simple step-by-step plan to a healthy lifestyle. Rob Thompson, MD and Dana Carpender create the ultimate dream team in your journey to wellness.The Insulin Resistance Solution offers a step-by-step plan and 75 recipes for reversing even the most stubborn insulin resistance.The Program:- Reduce Your Body's Demand for Insulin: This is the stumbling block of many other plans/doctor recommendations. Even "healthy" and "moderate" carb intake can continue to fuel insulin resistance.- Fat is Not the Enemy: Stop Worrying about Fat, Cholesterol, and Salt- Exercise--the RIGHT way:- Use Carb Blockers: Eat and Supplement to Slow Glucose Digestion and Lower Insulin Levels- Safe, Effective Medication

    This is type of problems asked at the JEE (IIT). The purpose of this book is to show students how to handle such problems and give them sufficient practice in solving problems of this type, thus building their confidence. The main features of this book are:Each chapter begins with a summary of facts, formulate and working techniques. Trick, tips and techniques have been clearly marked with the icon.A large number of problems have been solved and explained in each chapter.The exercises contain short-answer, long-answer and objective type questions.Multiple-choice questions in which more than one option may be correct have also been given.Time-bound tests at the end of each chapter will help students practise answering questions in a given time.The book also includes integrated tests, bases on all the chapters.A chapter containing miscellaneous problems has been given at the end of the book. This will help students gain confidence in solving problems without prior knowledge of the chapter(s) to which the problems belong.Table of ContentsAlgebraProgressions, Related Inequalities and SeriesDeterminants and Cramer's RuleEquations, Inequations and ExpressionsComplex NumbersPermutation and CombinationBinomial Theorem for Positive Integral IndexPrinciple of Mathematical Induction (PMI)Infinite SeriesMatricesTrigonometryCircular Functions, IdentitiesSolution of EquationsInverse Circular FunctionsTrigonometrical Inequalities and InequationsLogarithmProperties of TriangleHeights and DistancesCoordinate GeometryCoordinates and Straight LinesPairs of Straight Lines and Transformation of AxesCirclesParabolaEllipse and HyperbolaCalculusFunctionDifferentiationLimit, Indeterminate FormContinuity, Differentiability and Graph of FunctionApplication of dy/dxMaxima and MinimaMonotonic Function and Lagrange's TheoremIndefinite In

    WHO WAS THOMAS PAINE?Thomas Paine is known as one of the Fathers of the American Revolution. His landmark work, ‘Common Sense’, is known as the major inspiration for the ‘Declaration of Independence’, and his ‘Crisis’ pamphlet series was a favourite of George Washington to read out loud to inspire his troops at Valley Forge.Paine’s work is passionate, radical, yet accessible; covering his strong beliefs in Independence, Personal Liberty, Politics, Religion and Government. Hugely successful and inspiring strong polarisation in their times, they are still must-reads today, still highly debated and revered.THE 'MUST-HAVE' COMPLETE COLLECTIONIn this irresistible collection you get a full set of this amazing work.YOU GET:*COMMON SENSE - the famous work that inspired the American colonists with a demand and call for freedom from British rule. Also notable, that when adjusted for the population size of 1776, ‘Common Sense’ has the largest sales and circulation of any book in American history.*THE AMERICAN CRISIS - a series of pamphlets published from 1776 to 1783 written to motivate the Troops during the revolution, to spur them to victory. The language is powerful and emotional, and reflects Paine's liberal philosophies. The first lines are the famous: “These are times that try men’s souls.”*THE RIGHTS OF MAN (PART I and PART II) – a radical set of books that argues that political revolution is required when a government does not safeguard its people.*THE AGE OF REASON (PART I and PART II) - a deistic work, about institutionalized religion, and Paine’s strong views concerning it.*LETTERS and MISCELLANEOUS WRITINGS – A FULL SET of Paine’s must-read letters and assorted short works from Paine, Including his famous ‘LETTER TO GEORGE WASHINGTON’ and his last work ‘AGRAGIAN JUSTICE’YOUR FREE BONUSESIn addition, you get Free Special Bonuses:*THOMAS PAINE, BIOGRAPHY – A fascinating 10 page biography, detailing Paine’s unbelievable, often sad, and often controversial life. *Works presented as far as possible in original publication date order so you can follow Paine’s growth as a writer and philosopher*Easy TABLE OF CONTENTS so you can easily jump to any book, chapter or letter in the collection.YOUR NEW WINDOW INTO THOMAS PAINEImagine the wonder of having this fantastic, enviable collection, that rivals many libraries, right at your fingertips. Imagine the pleasure of discovering more about Paine’s one of a kind works.DON’T MISS OUT!As you read this, you understand why you want this edition, because it is the best, most complete Thomas Paine collection you can get. You want the most complete collection so don’t deny yourself! And don't accept other collections that are lacking. And available on the Kindle, this big collection is yours for next to nothing.

    A single father with a secret of his own, will do anything to give his daughter a better life, but the sacrifice may be greater than anything he could have ever imagined. Five years after the Chinese Axis detonated an unknown weapon of mass destruction off the southern coast of the United States, Special Ops Sergeant John Crider and the members of Shadow Company have finally captured what they all hope will lead to the end of the war. Unfortunately, the population within the United States is no longer sustainable. In an effort to stabilize the economy, the government enacts the Cryonics Act. One hundred years in suspended animation, all debt forgiven, and a chance at a less crowded future are too good to pass up for John and his young daughter. Except not everything always goes as planned as Sergeant John Crider finds himself pitted against a land of prehistoric monsters genetically resurrected from the fossil record, murderous inhabitants, and a future he never wanted.

    Part 1 focused on the ways governments count and report Covid-19 deaths. Part 2 covered the history of lockdowns and the evidence that they work - or don't. And Part 3 gave the same treatment to masks and mask mandates.All three booklets draw on primary sources like Centers for Disease Control reports, news articles, and scientific papers - and all three offer direct links to the material so that you the reader can judge it for yourself.With a quarter-million copies sold, Unreported Truths has become an independent journalism phenomenon. And as the fight over our response to Covid drags on, knowing the facts is more important than ever! Now, for the first time, all three booklets are available in a single package. Whether you are wondering about the series, have read one booklet but are interested in the others, or simply want them together for convenience, the Combined Edition offers fresh flexibility.With a new introduction!

    One morning he misses his bus when he stops to put a strange caterpillar in a matchbox. As the bus passes he’s shocked to spot himself inside. Like Schrödinger’s Cat in the famous quantum thought experiment, the caterpillar's spawned parallel possibilities. This comic novel explores Graham’s search for a better life among the various overlapping alternatives.Another clone, Grim Dupeint, is a loathsome international arms dealer. Graham infiltrates Grim’s corporation, then embezzles cash for charity. When a furious Grim realises, Graham must act fast. And right now he's acting like fish food.Graham launches upon a new lifestyle (and sex life) as he dons the designer suits of power. But sinister figures soon see through Graham’s clothing. Now Graham’s under attack from the corporation, the police, his ex-wife’s private detective, and an infuriatingly pompous water-colourist who Graham might have been if he’d gone to art college rather than business school. To survive (and steal the artist’s wonderful woman) Graham needs to find hidden resources. By definition Dopplegraham’s equally resourceful. Bugger...Schrödinger's Caterpillar - a stupid book for brainy people!

    It expands on the foundation acquired in chemistry courses and enables students to understand the mechanisms as they come across them in your classroom or laboratory.Organic Reaction Mechanisms provides extensive coverage of various organic reaction and rearrangements with emphasis on their applications in syntheses. The authors discuss reaction pathways, such as substitutions, additions, eliminations, oxidations, reductions, aromatic substitutions, aliphatic nucleophilic substitution, and electrophilic substitutions with numerous reaction equations to show the mechanism. The text also details the various reaction intermediates, including carbocations, carbanions, free radicals, carbenes, nitrines, benzynes, arynes, ylides, and enamines.Furthermore, the reagents are surveyed throughout the text, and correlation tables are provided to aid in identifying which oxidation/reduction agents to use for oxidizing/reducing various types of compounds. The applications of organic reagents are illustrated with examples and problems at the end of each chapter, which also serve to review the mechanisms learned and topics discussed. A comprehensive discussion on organic reactions, Organic Reaction Mechanisms will benefit advanced undergraduate and graduate chemistry students in their understanding and application of organic syntheses.

    Chemistry professor and syndicated Washington Post food columnist Robert L. Wolke provides over 100 reliable and witty explanations, while debunking misconceptions and helping you to see through confusing advertising and labeling.

    Yet today, science and its practitioners have come under political attack. In this fascinating history spanning continents and centuries, historian David Wootton offers a lively defense of science, revealing why the Scientific Revolution was truly the greatest event in our history.The Invention of Science goes back five hundred years in time to chronicle this crucial transformation, exploring the factors that led to its birth and the people who made it happen. Wootton argues that the Scientific Revolution was actually five separate yet concurrent events that developed independently, but came to intersect and create a new worldview. Here are the brilliant iconoclasts—Galileo, Copernicus, Brahe, Newton, and many more curious minds from across Europe—whose studies of the natural world challenged centuries of religious orthodoxy and ingrained superstition.From gunpowder technology, the discovery of the new world, movable type printing, perspective painting, and the telescope to the practice of conducting experiments, the laws of nature, and the concept of the fact, Wotton shows how these discoveries codified into a social construct and a system of knowledge. Ultimately, he makes clear the link between scientific discovery and the rise of industrialization—and the birth of the modern world we know.

    Starting once again with fossils, he turns his gaze skyward, showing us how the entirety of the universe’s fourteen-billion-year history can be seen in our bodies. As he moves from our very molecular composition (a result of stellar events at the origin of our solar system) through the workings of our eyes, Shubin makes clear how the evolution of the cosmos has profoundly marked our own bodies. Fully illustrated with black and white drawings.

    A twenty-eight year old — and not widely famous — Christopher Wren was giving a lecture on astronomy. As his audience listened to him speak, they decided that it would be a good idea to create a Society to promote the accumulation of useful knowledge.With that, the Royal Society was born. Since its birth, the Royal Society has pioneered scientific exploration and discovery. Isaac Newton, Charles Darwin, Albert Einstein, Robert Hooke, Robert Boyle, Joseph Banks, Humphry Davy, Isambard Kingdom Brunel, John Locke, Alexander Fleming — all were fellows.Bill Bryson’s favourite fellow was Reverend Thomas Bayes, a brilliant mathematician who devised Bayes’ theorem. Its complexity meant that it had little practical use in Bayes’ own lifetime, but today his theorem is used for weather forecasting, astrophysics and stock market analysis. A milestone in mathematical history, it only exists because the Royal Society decided to preserve it — just in case. The Royal Society continues to do today what it set out to do all those years ago. Its members have split the atom, discovered the double helix, the electron, the computer and the World Wide Web. Truly international in its outlook, it has created modern science.Seeing Further celebrates its momentous history and achievements, bringing together the very best of science writing. Filled with illustrations of treasures from the Society’s archives, this is a unique, ground-breaking and beautiful volume, and a suitable reflection of the immense achievements of science.

    Scientists are confident that there is alien life across the universe yet we have not moved beyond our perception of 'aliens' as Hollywood stereotypes. The time has come to abandon our fixation on alien monsters and place our expectations on solid scientific footing.Using his own expert understanding of life on Earth and Darwin's theory of evolution - which applies throughout the universe - Cambridge zoologist Dr Arik Kershenbaum explains what alien life must be like: how these creatures will move, socialise and communicate.For example, by observing fishes whose electrical pulses indicate social status, we can see that other planets might allow for communication by electricity. As there was evolutionary pressure to wriggle along a sea floor, Earthling animals tend to have left/right symmetry; on planets where creatures evolved mid-air or in soupy tar they might be lacking any symmetry at all.Might there be an alien planet with supersonic animals? Will they scream with fear, act honestly, or have technology? Is the universe swarming with robots? Dr Kershenbaum uses cutting-edge science to paint an entertaining and compelling picture of extra-terrestrial life.The Zoologist's Guide to the Galaxy is the story of how life really works, on Earth and in space.***'If you don't want to be surprised by extraterrestrial life, look no further than this lively overview of the laws of evolution that have produced life on earth' - Frans de Waal, author of Mama's Last Hug - Animal Emotions and What They Tell Us about Ourselves'A fun, and thoroughly biological, exploration of possible and impossible alien beings. If you'd love to know what real aliens from other planets might really be like, this is the book for you' - Susan Blackmore, author of Seeing Myself'Surveying the deep-time of evolution on Earth and his own cutting-edge research into animal communication, Kershenbaum provides a fascinating insight into the deepest of questions: what might an alien actually look like'- Lewis Dartnell, author of Origins'Arik Kershenbaum takes us on a joyous voyage of animal diversity and illustrates the singular importance of natural selection in explaining life - here on Earth - and what will likely be discovered throughout the galaxy. A stimulating read!' - Daniel T. Blumstein, Professor of Ecology and Evolutionary Biology, University of California Los Angeles

    Poe, The Other Einstein offers us a window into a brilliant, fascinating woman whose light was lost in Einstein's enormous shadow. It is the story of Einstein's wife, a brilliant physicist in her own right, whose contribution to the special theory of relativity is hotly debated and may have been inspired by her own profound and very personal insight.Mitza Maric has always been a little different from other girls. Most twenty-year-olds are wives by now, not studying physics at an elite Zurich university with only male students trying to outdo her clever calculations. But Mitza is smart enough to know that, for her, math is an easier path than marriage. And then fellow student Albert Einstein takes an interest in her, and the world turns sideways. Theirs becomes a partnership of the mind and of the heart, but there might not be room for more than one genius in a marriage.

    Feynman's contributions to twentieth-century physics, but few realize how engaged he was with the world around him -- how deeply and thoughtfully he considered the religious, political, and social issues of his day. Now, a wonderful book -- based on a previously unpublished, three-part public lecture he gave at the University of Washington in 1963 -- shows us this other side of Feynman, as he expounds on the inherent conflict between science and religion, people's distrust of politicians, and our universal fascination with flying saucers, faith healing, and mental telepathy. Here we see Feynman in top form: nearly bursting into a Navajo war chant, then pressing for an overhaul of the English language (if you want to know why Johnny can't read, just look at the spelling of "friend"); and, finally, ruminating on the death of his first wife from tuberculosis. This is quintessential Feynman -- reflective, amusing, and ever enlightening.