In this now-classic study, Michael Bliss unearths a wealth of material, ranging from scientists& unpublished memoirs to the confidential appraisals of insulin by members of the Nobel Committee. He also resolves a longstanding controversy dating to the awarding of the Nobel to F. G. Banting and J. J. R. Macleod for their work on insulin: because each insisted on sharing the credit with an additional associate, medical opinion was intensely divided over the allotment of credit for the discovery. Bliss also offers a wealth of new detail on such subjects as the treatment of diabetes before insulin and the life-and-death struggle to manufacture it.Bliss;s excellent account of the insulin story is a rare dissection of the anatomy of scientific discovery, and serves as a model of how rigorous historical method can correct the myths and legends sometimes perpetrated in the scientific literature.

    With its earliest invention, the mirror allowed us to gaze upon ourselves, bestowing a power both fascinating and terrifying.

    That does not mean that his head was in the clouds, or that the particular sciences lacked interest for him. Not at all--he felt a lively concern for theological debate, he was a mathematician of the first rank, he made original contributions to physics, he gave a realistic attention to moral psychology. But he was incapable of looking at the objects of any special enquiry without seeing them as aspects or parts of one intelligible universe. He strove constantly after system, and the instrument on which his effort relied was the speculative reason. He embodied in an extreme form the spirit of his age. Nothing could be less like the spirit of ours. To many people now alive metaphysics means a body of wild and meaningless assertions resting on spurious argument. A professor of metaphysics may nowadays be held to deal handsomely with theduties of his chair if he is prepared to handle metaphysical statements at all, though it be only for the purpose of getting rid of them, by showing them up as confused forms of something else. A chair in metaphysical philosophy becomes analogous to a chair in tropical diseases: what is taught from it is not the propagation but the cure.Confidence in metaphysical construction has ebbed and flowed through philosophical history; periods of speculation have been followed by periods of criticism. The tide will flow again, but it has not turned yet, and [8] such metaphysicians as survive scarcely venture further than to argue a case for the possibility of their art. It would be an embarrassing task to open an approach to Leibnitian metaphysics from the present metaphysical position, if there is a present position. If we want an agreed starting-point, it will have to be historical.The historical importance of Leibniz's ideas is anyhow unmistakable. If metaphysical thinking is nonsensical, its empire over the human imagination must still be confessed; if it is as chimerical a science as alchemy, it is no less fertile in by-products of importance. And if we are to consider Leibniz historically, we cannot do better than take up his _Theodicy_, fortwo reasons. It was the only one of his main philosophical works to be published in his lifetime, so that it was a principal means of his direct influence; the Leibniz his own age knew was the Leibniz of the _Theodicy_. Then in the second place, the _Theodicy_ itself is peculiarly rich in historical material. It reflects the world of men and books which Leibnizknew; it expresses the theological setting of metaphysical speculation which still predominated in the first years of the eighteenth century........

    In his first novel in ten years, Dennis Cooper writes about George Miles, love, loss, addiction, suicide, and how fiction can capture these things, and how it fails to capture them. Candid and powerful, I Wished is a radical work of shifting forms. It includes appearances by Santa Claus, land artist James Turrell, sentient prairie dogs, John Wayne Gacy, Nick Drake, and George, the muse for Cooper’s acclaimed novels Closer, Frisk, Try, Guide, and Period, collectively known as “The George Miles Cycle.” In revisiting the inspiration for the Cycle, Dennis has written a masterwork: the most raw, personal, and haunted book of his career.

    But as the couple pored over the Unabomber's seventy-eight page manifesto, David couldn't rule out the possibility. It slowly became clear to them that Ted was likely responsible for mailing the seventeen bombs that killed three people, and injured many more. Wanting to prevent further violence, David made the agonizing decision to turn his brother in to the FBI.Every Last Tie is David's highly personal, and powerful, memoir of his family, as well as a meditation on the possibilities for reconciliation and maintaining family bonds. Seen through David's eyes, Ted was a brilliant, yet troubled, young mathematician, and a loving older brother. Their parents were supportive, and emphasized to their sons the importance of education and empathy. But as Ted grew older he became more and more withdrawn, his behavior became increasingly erratic, and he often sent angry letters to his family from his isolated cabin in rural Montana.During Ted's trial David worked hard to save Ted from the death penalty, and since then he has been a leading activist in the anti–death penalty movement. The book concludes with an afterword by psychiatry professor, and forensic psychiatrist, James L. Knoll IV, who discusses the current challenges facing the mental health system in the United States, as well as the link between mental illness and violence.

    This book offers a selection of seven of Foucault's most important published essays, translated from the French, with an introductory essay and notes by Donald F. Bouchard. Also included are a summary of a course given by Foucault at Collège de France, the transcript of a conversation between Foucault and Gilles Deleuze, and an interview with Foucault that appeared in the journal Actuel.

    Trump as darkly symptomatic of a deeper societal distress. Equally challenging and profound, Twlilight of American Sanity makes sense of our time and charts the way forward.It is comforting to see President Donald Trump as a crazy man, a one-off, an exception—not a reflection on us or our democracy. But in ways I never anticipated, his rise was absolutely predictable and a mirror on our soul. … What does it say about us, that we elected someone so manifestly unfit and unprepared to determine mankind’s future? Trump is a symptom of a world in distress, not its sole cause. Blaming him for all our troubles misses the deeper, underlying societal sickness that made possible his unlikely ascent. Calling Trump crazy allows us to avoid confronting the craziness in our society—if we want to get sane, we must first gain insight about ourselves. Simply put: Trump isn’t crazy, but our society is. – from TWILIGHT OF AMERICAN SANITYMore than three years in the making: the world's leading expert on psychiatric diagnosis, past leader of the American Psychiatric Association’s DSM (“the bible of psychology”), and author of the influential international bestseller on the medicalization of ordinary life, Saving Normal, draws upon his vast experience to deliver a powerful critique of modern American society’s collective slide away from sanity and offers an urgently needed prescription for reclaiming our bearings. Widely cited in recent months as the man who quite literally wrote the diagnostic criteria for narcissism, Allen Frances, M.D., has been at the center of the debate surrounding President Trump’s mental state—quoted in Evan Osnos’s May 2017 New Yorker article (“How Trump Could Get Fired”) and publishing a much-shared opinion letter in the New York Times (“An Eminent Psychiatrist Demurs on Trump’s Mental State”). Frances argues that Trump is "bad, not mad"--and that the real question to wrestle with is how we as a country could have chosen him as our leader. Twilight of American Sanity is an essential work for understanding our national crisis.

    She was arrested on the charge of witchcraft in June of 1663. She was found guilty and was executed on December 30th that same year. Her trial was long and involved, with many witnesses from several towns and villages.Consisting of direct translations of the trial testimony, The Trial of Tempel Anneke portrays a large and varied cast of characters including trades people, farmers, local nobility, village drunkards, and Tempel Anneke herself. Tempel Anneke was in several ways typical of those accused of witchcraft, yet from the testimony she emerges as a complex and controversial figure. She was literate and owned a few books and herbals; she prided herself on her medical and pharmaceutical knowledge and until the final stages of the trial when her confession was extracted under torture, she was sharp, assertive, and even witty in her responses to questioning. This English translation offers direct archival insight into the workings of 17th century law, contemporary understandings of justice, perceptions of natural and magical causes, and above all, the social history of the period.While other witchcraft materials exist, this is the only text available in English that allows students to follow a witchcraft trial from beginning to end. Highly readable, this astonishing narrative is perfectly suited to being read as a complete document. The useful additions of introduction, appendices, glossary, and index provide readers with important background information so that they can engage directly with the material.

    After decorating the walls with art by Picasso and other avant-garde artists, they embarked on a series of extravagant performances. Three readers simultaneously recited a poem in three languages; a monocle-wearing teenager performed a spell from New Zealand; another young man sneered at the audience, snapping a whip as he intoned his “Fantastic Prayers.” One of the artists called these sessions “both buffoonery and a requiem mass.” Soon they would have a more evocative name: Dada. In Destruction Was My Beatrice, modernist scholar Jed Rasula presents the first narrative history of Dada, showing how this little-understood artistic phenomenon laid the foundation for culture as we know it today. Although the venue where Dada was born closed after only four months and its acolytes scattered, the idea of Dada quickly spread to New York, where it influenced artists like Marcel Duchamp and Man Ray; to Berlin, where it inspired painters George Grosz and Hannah Höch; and to Paris, where it dethroned previous avant-garde movements like Fauvism and Cubism while inspiring early Surrealists like André Breton, Louis Aragon, and Paul éluard. The long tail of Dadaism, Rasula shows, can be traced even further, to artists as diverse as William S. Burroughs, Robert Rauschenberg, Marshall McLuhan, the Beatles, Monty Python, David Byrne, and Jean-Michel Basquiat, all of whom—along with untold others—owe a debt to the bizarre wartime escapades of the Dada vanguard. A globe-spanning narrative that resurrects some of the 20th century’s most influential artistic figures, Destruction Was My Beatrice describes how Dada burst upon the world in the midst of total war—and how the effects of this explosion are still reverberating today.

    G. Jung laid the groundwork for a psychology of the spirit. The excerpts here illuminate the concept of the unconscious, the central pillar of his work, and display ample evidence of the spontaneous spiritual and religious activities of the human mind. This compact volume will serve as an ideal introduction to Jung's basic concepts.Part I of this book, "On the Nature and Functioning of the Psyche, " contains material from four works: "Symbols of Transformation, " "On the Nature of the Psyche, " "The Relations between the Ego and the Unconscious, " and "Psychological Types." Also included in Part I are "Archetypes of the Collective Unconscious" and "Psychological Aspects of the Mother Archetype." Part II, "On Pathology and Therapy, " includes "On the Nature of Dreams, " "On the Pathogenesis of Schizophrenia, " selections from "Psychology of the Transference." In Part III appear "Introduction to the Religious and Psychological Problems of Alchemy" and two sections of "Psychology and Religion." Part IV, called "On Human Development, " consists of the essay "Marriage as a Psychological Relationship."

    Mettler argues that this difficulty is not merely a failure of communication; rather it is endemic to the formidable presence of the “submerged state.” In recent decades, federal policymakers have increasingly shunned the outright disbursing of benefits to individuals and families and favored instead less visible and more indirect incentives and subsidies, from tax breaks to payments for services to private companies. These submerged policies, Mettler shows, obscure the role of government and exaggerate that of the market. As a result, citizens are unaware not only of the benefits they receive, but of the massive advantages given to powerful interests, such as insurance companies and the financial industry. Neither do they realize that the policies of the submerged state shower their largest benefits on the most affluent Americans, exacerbating inequality. Mettler analyzes three Obama reforms—student aid, tax relief, and health care—to reveal the submerged state and its consequences, demonstrating how structurally difficult it is to enact policy reforms and even to obtain public recognition for achieving them. She concludes with recommendations for reform to help make hidden policies more visible and governance more comprehensible to all Americans. The sad truth is that many American citizens do not know how major social programs work—or even whether they benefit from them. Suzanne Mettler’s important new book will bring government policies back to the surface and encourage citizens to reclaim their voice in the political process.

    When those feelings have been stirred, and they act in their due degree, there ensues what may be called the state of Harmony. This Equilibrium is the great root from which grow all the human actings in the world, and this Harmony is the universal path which they all should pursue.

    But the same things that have made it so have also made a good marriage more fulfilling than ever before. In this enlightening and hugely entertaining book, historian and marriage expert Stephanie Coontz takes readers from the marital intrigues of ancient Babylon to the sexual torments of Victorian couples to demonstrate how recent the idea of marrying for love is-and how absurd it would have seemed to most of our ancestors. It was only 200 years ago that marriage began to be about love and emotional commitment, and since then the very things that have strengthened marriage as a personal relationship have steadily weakened it as a social institution. Marriage, A History brings intelligence, wit, and some badly needed perspective to today's marital debates and dilemmas.

    Two leading psychologists explain what causes boredom and how to listen to what it is telling you, so you can live a more engaged life.We avoid boredom at all costs. It makes us feel restless and agitated. Desperate for something to do, we play games on our phones, retie our shoes, or even count ceiling tiles. And if we escape it this time, eventually it will strike again. But what if we listened to boredom instead of banishing it?Psychologists James Danckert and John Eastwood contend that boredom isn't bad for us. It's just that we do a bad job of heeding its guidance. When we're bored, our minds are telling us that whatever we are doing isn't working--we're failing to satisfy our basic psychological need to be engaged and effective. Too many of us respond poorly. We become prone to accidents, risky activities, loneliness, and ennui, and we waste ever more time on technological distractions. But, Danckert and Eastwood argue, we can let boredom have the opposite effect, motivating the change we need. The latest research suggests that an adaptive approach to boredom will help us avoid its troubling effects and, through its reminder to become aware and involved, might lead us to live fuller lives.Out of My Skull combines scientific findings with everyday observations to explain an experience we'd like to ignore, but from which we have a lot to learn. Boredom evolved to help us. It's time we gave it a chance.

    Here and there, we can supplement these meager scraps by the use of biochemical markers or geochemical signatures that add useful information, but, even with such additional help, our reconstructions and our models of descent are often tentative. For the fossil record is, as we have seen, as biased as it is incomplete. But fragmentary, selective, and biased though it is, the fossil record, with all its imperfections, is still a treasure. Though whole chapters are missing, many pages lost, and the earliest pages so damaged as to be, as yet, virtually unreadable, this--the greatest biography of all--is one in whose closing pages we find ourselves.--from OriginsIn Origins, Frank H. T. Rhodes explores the origin and evolution of living things, the changing environments in which they have developed, and the challenges we now face on an increasingly crowded and polluted planet. Rhodes argues that the future well-being of our burgeoning population depends in no small part on our understanding of life's past, its long and slow development, and its intricate interdependencies.Rhodes's accessible and extensively illustrated treatment of the origins narrative describes the nature of the search for prehistoric life, the significance of geologic time, the origin of life, the emergence and spread of flora and fauna, the evolution of primates, and the emergence of modern humans.