Beginning with the study of DNA in Egyptian mummies in the early 1980s and culminating in the sequencing of the Neanderthal genome in 2010, Neanderthal Man describes the events, intrigues, failures, and triumphs of these scientifically rich years through the lens of the pioneer and inventor of the field of ancient DNA.We learn that Neanderthal genes offer a unique window into the lives of our hominin relatives and may hold the key to unlocking the mystery of why humans survived while Neanderthals went extinct. Drawing on genetic and fossil clues, Pääbo explores what is known about the origin of modern humans and their relationship to the Neanderthals and describes the fierce debate surrounding the nature of the two species’ interactions. His findings have not only redrawn our family tree, but recast the fundamentals of human history—the biological beginnings of fully modern Homo sapiens, the direct ancestors of all people alive today.A riveting story about a visionary researcher and the nature of scientific inquiry, Neanderthal Man offers rich insight into the fundamental question of who we are.

    Into this crisis stepped Walter Freeman, M.D., who saw a solution in lobotomy, a brain operation intended to reduce the severity of psychotic symptoms. Drawing on Freeman’s documents and interviews with Freeman's family, Jack El-Hai takes a penetrating look at the life and work of this complex scientific genius.The Lobotomist explores one of the darkest chapters of American medicine: the desperate attempt to treat the hundreds of thousands of psychiatric patients in need of help during the middle decades of the twentieth century. Into this crisis stepped Walter Freeman, M.D., who saw a solution in lobotomy, a brain operation intended to reduce the severity of psychotic symptoms. Although many patients did not benefit from the thousands of lobotomies Freeman performed, others believed their lobotomies changed them for the better. Drawing on a rich collection of documents Freeman left behind and interviews with Freeman's family, Jack El-Hai takes a penetrating look into the life of this complex scientific genius and traces the physician's fascinating life and work.

    The outcome was unexpected—when Henry awoke, he could no longer form new memories, and for the rest of his life would be trapped in the moment. But Henry’s tragedy would prove a gift to humanity. As renowned neuroscientist Suzanne Corkin explains in Permanent Present Tense, she and her colleagues brought to light the sharp contrast between Henry’s crippling memory impairment and his preserved intellect. This new insight that the capacity for remembering is housed in a specific brain area revolutionized the science of memory. The case of Henry—known only by his initials H. M. until his death in 2008—stands as one of the most consequential and widely referenced in the spiraling field of neuroscience. Corkin and her collaborators worked closely with Henry for nearly fifty years, and in Permanent Present Tense she tells the incredible story of the life and legacy of this intelligent, quiet, and remarkably good-humored man. Henry never remembered Corkin from one meeting to the next and had only a dim conception of the importance of the work they were doing together, yet he was consistently happy to see her and always willing to participate in her research. His case afforded untold advances in the study of memory, including the discovery that even profound amnesia spares some kinds of learning, and that different memory processes are localized to separate circuits in the human brain. Henry taught us that learning can occur without conscious awareness, that short-term and long-term memory are distinct capacities, and that the effects of aging-related disease are detectable in an already damaged brain.Undergirded by rich details about the functions of the human brain, Permanent Present Tense pulls back the curtain on the man whose misfortune propelled a half-century of exciting research. With great clarity, sensitivity, and grace, Corkin brings readers to the cutting edge of neuroscience in this deeply felt elegy for her patient and friend.

    Several biographies have chronicled her stardom, but none has covered her intense experiences through five years of Nazi occupation in the Netherlands. According to her son, Luca Dotti, “The war made my mother who she was.” Audrey Hepburn’s war included participation in the Dutch Resistance, working as a doctor’s assistant during the “Bridge Too Far” battle of Arnhem, the brutal execution of her uncle, and the ordeal of the Hunger Winter of 1944. She also had to contend with the fact that her father was a Nazi agent and her mother was pro-Nazi for the first two years of the occupation. But the war years also brought triumphs as Audrey became Arnhem’s most famous young ballerina. Audrey’s own reminiscences, new interviews with people who knew her in the war, wartime diaries, and research in classified Dutch archives shed light on the riveting, untold story of Audrey Hepburn under fire in World War II.

    As one of the launch titles in Atlantic Monthly Press’ “Books That Changed the World” series, Browne’s history takes readers inside The Origin of the Species and shows why it can fairly claim to be the greatest science book ever published.

    This elegant, humane, and engaging book "captures what we know of the development of what makes us human" (Nature).Visit Armand Marie Leroi on the web: http: //armandleroi.com/index.htmlStepping effortlessly from myth to cutting-edge science,

    She explores the culture of genealogy buffs, the science of DNA, and the business of companies like Ancestry and 23andMe, all while tracing the story of one woman, her unusual results, and a relentless methodical drive for answers that becomes a thoroughly modern genetic detective story.

    His breaking of the German U-boat Enigma cipher in World War II ensured Allied-American control of the Atlantic. But Turing's vision went far beyond the desperate wartime struggle. Already in the 1930s he had defined the concept of the universal machine, which underpins the computer revolution. In 1945 he was a pioneer of electronic computer design. But Turing's true goal was the scientific understanding of the mind, brought out in the drama and wit of the famous "Turing test" for machine intelligence and in his prophecy for the twenty-first century.Drawn in to the cockpit of world events and the forefront of technological innovation, Alan Turing was also an innocent and unpretentious gay man trying to live in a society that criminalized him. In 1952 he revealed his homosexuality and was forced to participate in a humiliating treatment program, and was ever after regarded as a security risk. His suicide in 1954 remains one of the many enigmas in an astonishing life story.

    Robert Oppenheimer, "father of the atomic bomb," the brilliant, charismatic physicist who led the effort to capture the awesome fire of the sun for his country in time of war. Immediately after Hiroshima, he became the most famous scientist of his generation-one of the iconic figures of the twentieth century, the embodiment of modern man confronting the consequences of scientific progress. He was the author of a radical proposal to place international controls over atomic materials-an idea that is still relevant today. He opposed the development of the hydrogen bomb and criticized the Air Force's plans to fight an infinitely dangerous nuclear war. In the now almost-forgotten hysteria of the early 1950s, his ideas were anathema to powerful advocates of a massive nuclear buildup, and, in response, Atomic Energy Commission chairman Lewis Strauss, Superbomb advocate Edward Teller and FBI director J. Edgar Hoover worked behind the scenes to have a hearing board find that Oppenheimer could not be trusted with America's nuclear secrets. American Prometheus sets forth Oppenheimer's life and times in revealing and unprecedented detail. Exhaustively researched, it is based on thousands of records and letters gathered from archives in America and abroad, on massive FBI files and on close to a hundred interviews with Oppenheimer's friends, relatives and colleagues.We follow him from his earliest education at the turn of the twentieth century at New York City's Ethical Culture School, through personal crises at Harvard and Cambridge universities. Then to Germany, where he studied quantum physics with the world's most accomplished theorists; and to Berkeley, California, where he established, during the 1930s, the leading American school of theoretical physics, and where he became deeply involved with social justice causes and their advocates, many of whom were communists. Then to Los Alamos, New Mexico, where he transformed a bleak mesa into the world's most potent nuclear weapons laboratory-and where he himself was transformed. And finally, to the Institute for Advanced Study in Princeton, which he directed from 1947 to 1966. American Prometheus is a rich evocation of America at midcentury, a new and compelling portrait of a brilliant, ambitious, complex and flawed man profoundly connected to its major events—the Depression, World War II and the Cold War. It is at once biography and history, and essential to our understanding of our recent past—and of our choices for the future.

    New findings in molecular biology challenge the gene-centered version of Darwinian theory according to which adaptation occurs only through natural selection of chance DNA variations. In Evolution in Four Dimensions, Eva Jablonka and Marion Lamb argue that there is more to heredity than genes. They trace four dimensions in evolution -- four inheritance systems that play a role in evolution: genetic, epigenetic (or non-DNA cellular transmission of traits), behavioral, and symbolic (transmission through language and other forms of symbolic communication). These systems, they argue, can all provide variations on which natural selection can act. Evolution in Four Dimensions offers a richer, more complex view of evolution than the gene-based, one-dimensional view held by many today. The new synthesis advanced by Jablonka and Lamb makes clear that induced and acquired changes also play a role in evolution. After discussing each of the four inheritance systems in detail, Jablonka and Lamb put Humpty Dumpty together again by showing how all of these systems interact. They consider how each may have originated and guided evolutionary history and they discuss the social and philosophical implications of the four-dimensional view of evolution. Each chapter ends with a dialogue in which the authors engage the contrarieties of the fictional (and skeptical) I.M., or Ifcha Mistabra -- Aramaic for the opposite conjecture -- refining their arguments against I.M.'s vigorous counterarguments. The lucid and accessible text is accompanied by artist-physician Anna Zeligowski's lively drawings, which humorously and effectively illustrate the authors' points.

    This book gives details of their research and investigations into the use of psychedelic drugs for the study of the human mind, and is also a love story. The second half of the book describes in detail a wealth of phenethlyamines, their physical properties, dosages used, duration of effects observed, and commentary on effects.

    McGregor, and many other Beatrix Potter characters remain in the hearts of millions. However, though Potter is a household name around the world, few know the woman behind the illustrations. Her personal life, including a romantic relationship with her publisher, Norman Warne, and her significant achievements outside of children's literature remain largely unknown. In Linda Lear's enchanting new biography, we get the life story of this incredible, funny, and independent woman. As one of the first female naturalists in the world, Potter brought the beauty and importance of nature back into the imagination at a time when plunder was more popular than preservation. Through her art she sought to encourage conservation and change the world. With never before seen illustrations and intimate detail, Lear goes beyond our perrenial fascination with Potter as a writer and illustrator of children's books, and delves deeply into the life of a most unusual and gifted woman--one whose art was timeless, and whose generosity left an indelible imprint on the countryside.

    When Captain Robert FitzRoy, the twenty-six-year-old captain of the H.M.S. Beagle, set out for Tierra del Fuego in the fall of 1831, he invited a young naturalist to accompany him. That twenty-two-year-old gentleman was Charles Darwin, and perhaps no single voyage in history had a greater impact on how we would come to understand the world -- in both religious and scientific terms.When the Beagle's first captain committed suicide while at sea in 1828, he was replaced by a young naval officer of a new mold. Robert FitzRoy was the most brilliant and scientific sea captain of his age. He used the Beagle, a survey vessel, as a laboratory for the new field of the natural sciences. But his plan to bring four "savages" home to England to civilize them as Christian gentlefolk backfired when scandal loomed over their sexual misbehavior at the Walthamstow Infants School. FitzRoy needed to get them out of England fast, and thus was born the second and most famous voyage of the Beagle.FitzRoy feared the loneliness of another long voyage -- with madness in his own family, he was haunted by the fate of the Beagle's previous captain -- so for company he took with him the young amateur naturalist Charles Darwin. Like FitzRoy, Darwin believed, at the beginning of the voyage, in the absolute word of the Bible and the story of man's creation. The two men spent five years circling the globe together, but by the end of their voyage they had reached startlingly different conclusions about the origins of the natural world.In naval terms, the voyage was a stunning scientific success. But FitzRoy, a fanatical Christian, was horrified by the heretical theories Darwin began to develop. As these began to influence the profoundest levels of religious and scientific thinking in the nineteenth century, FitzRoy's knowledge that he had provided Darwin with the vehicle for his sacrilegious ideas propelled him down an irrevocable path to suicide.This true story -- part biography, part sea drama, and a subtle study of one of the defining moments in the history of science -- reads like the finest historical fiction. It is a chronicle of the remarkable chain of events without which Darwin would most likely have lived and died an obscure English country parson with a fondness for collecting beetles.

    The Lady and Her Monsters by Roseanne Motillo brings to life the fascinating times, startling science, and real-life horrors behind Mary Shelley’s gothic masterpiece, Frankenstein.Montillo recounts how—at the intersection of the Romantic Age and the Industrial Revolution—Shelley’s Victor Frankenstein was inspired by actual scientists of the period: curious and daring iconoclasts who were obsessed with the inner workings of the human body and how it might be reanimated after death.With true-life tales of grave robbers, ghoulish experiments, and the ultimate in macabre research—human reanimation—The Lady and Her Monsters is a brilliant exploration of the creation of Frankenstein, Mary Shelley’s horror classic.

    Now, in The New Science of the Human Past, Reich describes just how the human genome provides not only all the information that a fertilized human egg needs to develop but also contains within it the history of our species. He delineates how the Genomic Revolution and ancient DNA are transforming our understanding of our own lineage as modern humans; how genomics deconstructs the idea that there are no biologically meaningful differences among human populations (though without adherence to pernicious racist hierarchies); and how DNA studies reveal the deep history of human inequality--among different populations, between the sexes, and among individuals within a population.