Two scientists explore the potential of a revolutionary genetics technology capable of easily and affordably manipulating DNA in human embryos to prevent specific diseases, addressing key concerns about related ethical and societal repercussions.

    S. Ramachandran is at the forefront of his field-so much so that Richard Dawkins dubbed him the "Marco Polo of neuroscience." Now, in a major new work, Ramachandran sets his sights on the mystery of human uniqueness. Taking us to the frontiers of neurology, he reveals what baffling and extreme case studies can teach us about normal brain function and how it evolved. Synesthesia becomes a window into the brain mechanisms that make some of us more creative than others. And autism--for which Ramachandran opens a new direction for treatment--gives us a glimpse of the aspect of being human that we understand least: self-awareness. Ramachandran tackles the most exciting and controversial topics in neurology with a storyteller's eye for compelling case studies and a researcher's flair for new approaches to age-old questions. Tracing the strange links between neurology and behavior, this book unveils a wealth of clues into the deepest mysteries of the human brain.

    In a way, you already know them. Only you don’t – not really. In a sense, they are you. Only they’re not entirely. They inform and shape the most important decisions in your life. But you’re almost certainly unaware of their intervention. They are the Ten Types of Human. Who are they? What are they for? How did they get into your head? We want to believe that there are some things we would never do. We want to believe that there are others we always would. But how can we be sure? What are our limits? Do we have limits?The answer lies with the Ten Types of Human: the people we become when we are faced with life's most difficult decisions. But who or what are these Types? Where do they come from? How did they get into our heads?The Ten Types of Human is a pioneering examination of human nature. It looks at the best and worst that human beings are capable of, and asks why. It explores the frontiers of the human experience, excavating the forces that shape our thoughts and actions in extreme situations. It begins in a courtroom and journeys across four continents and through the lives of some exceptional people, in search of answers.Mixing cutting-edge neuroscience, social psychology and visceral true stories, The Ten Types of Human is at once a provocation and a roadmap of the hidden parts of us. It is a book to inspire; to refashion our understanding of our many selves and semblances; and ultimately to find fresh ways to be free.

    It could be an oddball researcher’s genius insight, a catalyzing moment in geopolitical history, a new breakthrough technology, or an unexpected but welcome side effect discovered during clinical trials. Piece together these stories, as Thomas Hager does in this remarkable, century-spanning history, and you can trace the evolution of our culture and the practice of medicine.  ​Beginning with opium, the “joy plant,” which has been used for 10,000 years, Hager tells a captivating story of medicine. His subjects include the largely forgotten female pioneer who introduced smallpox inoculation to Britain, the infamous knockout drops, the first antibiotic, which saved countless lives, the first antipsychotic, which helped empty public mental hospitals, Viagra, statins, and the new frontier of monoclonal antibodies. This is a deep, wide-ranging, and wildly entertaining book.

    But Cal Newport knows that real straight-A students don't study harder--they study smarter. A breakthrough approach to acing academic assignments, from quizzes and exams to essays and papers, "How to Become a Straight-A Student" reveals for the first time the proven study secrets of real straight-A students across the country and weaves them into a simple, practical system that anyone can master. You will learn how to: Streamline and maximize your study time Conquer procrastinationAbsorb the material quickly and effectivelyKnow which reading assignments are critical--and which are notTarget the paper topics that wow professorsProvide A+ answers on examsWrite stellar prose without the agony A strategic blueprint for success that promises more free time, more fun, and top-tier results, "How to Become a Straight-A Student" is the only study guide written by students for students--with the insider knowledge and real-world methods to help you master the college system and rise to the top of the class.

    He has run over mountains, across Death Valley, and to the South Pole-and is probably the first person to eat an entire pizza while running. With an insight, candor, and humor rarely seen in sports memoirs (and written without the aid of a ghostwriter or cowriter), Ultramarathon Man has inspired tens of thousands of people-nonrunners and runners alike-to push themselves beyond their comfort zones and be reminded of what it feels like to be truly alive, says Sam Fussell, author of Muscle.Ultramarathon Man answers the questions Karnazes is continually asked:- Why do you do it?- How do you do it?- Are you insane?And in the new paperback edition, Karnazes answers the two questions he was most asked on his book tour:- What, exactly, do you eat?- How do you train to stay in such good shape?

    When you meet her on the trail, you might be surprised to see she doesn’t quite fit the typical image of a long-distance runner. She’s neither skinny nor white, and she’s here to show just how misguided these stereotypes can be.In this prejudice-busting, body-positive memoir told with raw honesty, an adventurous spirit, and a sharp sense of humor, Valerio takes readers along on her journey from first-time racer to ultramarathoner and proves that anyone can become a successful athlete.

    Smoking has gone from doctor recommended to deadly. We used to think the Earth was the center of the universe and that Pluto was a planet. For decades, we were convinced that the brontosaurus was a real dinosaur. In short, what we know about the world is constantly changing.   But it turns out there’s an order to the state of knowledge, an explanation for how we know what we know. Samuel Arbesman is an expert in the field of scientometrics—literally the science of science. Knowl­edge in most fields evolves systematically and predict­ably, and this evolution unfolds in a fascinating way that can have a powerful impact on our lives.   Doctors with a rough idea of when their knowl­edge is likely to expire can be better equipped to keep up with the latest research. Companies and govern­ments that understand how long new discoveries take to develop can improve decisions about allocating resources. And by tracing how and when language changes, each of us can better bridge gen­erational gaps in slang and dialect.   Just as we know that a chunk of uranium can break down in a measurable amount of time—a radioactive half-life—so too any given field’s change in knowledge can be measured concretely. We can know when facts in aggregate are obsolete, the rate at which new facts are created, and even how facts spread.   Arbesman takes us through a wide variety of fields, including those that change quickly, over the course of a few years, or over the span of centuries. He shows that much of what we know consists of “mesofacts”—facts that change at a middle timescale, often over a single human lifetime. Throughout, he of­fers intriguing examples about the face of knowledge: what English majors can learn from a statistical analysis of The Canterbury Tales, why it’s so hard to measure a mountain, and why so many parents still tell kids to eat their spinach because it’s rich in iron.   The Half-life of Facts is a riveting journey into the counterintuitive fabric of knowledge. It can help us find new ways to measure the world while accepting the limits of how much we can know with certainty.

    - One month to reset your metabolism for lasting fat loss - One week to discover the carbs that are right for you- With weekly shopping lists and over 70 fully-anglicised recipes In WIRED TO EAT, superstar US diet expert, Paleo sensation and New York Times bestselling author of THE PALEO SOLUTION Robb Wolf will show you how to change your eating habits for good, tailor your diet to fit your personal needs and shed weight fast – and never put it back on!

    And, according to Oprah Winfrey, "Your real job in life is to figure out as soon as possible what that is, who you are meant to be, and begin to honor your calling in the best way possible."That journey starts right here.In her latest book, The Path Made Clear, Oprah shares what she sees as a guide for activating your deepest vision of yourself, offering the framework for creating not just a life of success, but one of significance. The book's ten chapters are organized to help you recognize the important milestones along the road to self-discovery, laying out what you really need in order to achieve personal contentment, and what life's detours are there to teach us.Oprah opens each chapter by sharing her own key lessons and the personal stories that helped set the course for her best life. She then brings together wisdom and insights from luminaries in a wide array of fields, inspiring readers to consider what they're meant to do in the world and how to pursue it with passion and focus. These renowned figures share the greatest lessons from their own journeys toward a life filled with purpose.Paired with over 100 awe-inspiring photographs to help illuminate the wisdom of these messages, The Path Made Clear provides readers with a beautiful resource for achieving a life lived in service of your calling - whatever it may be.

    Tell a stranger that you talk to yourself, and you're likely to get written off as eccentric. But the truth is that we all have a voice in our head. When we talk to ourselves, we often hope to tap into our inner coach but find our inner critic instead. When we're facing a tough task, our inner coach can buoy us up: Focus--you can do this. But, just as often, our inner critic sinks us entirely: I'm going to fail. They'll all laugh at me. What's the use?In Chatter, acclaimed psychologist Ethan Kross explores the silent conversations we have with ourselves. Interweaving groundbreaking behavioral and brain research from his own lab with real-world case studies--from a pitcher who forgets how to pitch, to a Harvard undergrad negotiating her double life as a spy--Kross explains how these conversations shape our lives, work, and relationships. He warns that giving in to negative and disorienting self-talk--what he calls "chatter"--can tank our health, sink our moods, strain our social connections, and cause us to fold under pressure.But the good news is that we're already equipped with the tools we need to make our inner voice work in our favor. These tools are often hidden in plain sight--in the words we use to think about ourselves, the technologies we embrace, the diaries we keep in our drawers, the conversations we have with our loved ones, and the cultures we create in our schools and workplaces.Brilliantly argued, expertly researched, and filled with compelling stories, Chatter gives us the power to change the most important conversation we have each day: the one we have with ourselves.

    It now has 600,000 to a million page hits daily. Every now and then, Munroe would get emails asking him to arbitrate a science debate. 'My friend and I were arguing about what would happen if a bullet got struck by lightning, and we agreed that you should resolve it . . . ' He liked these questions so much that he started up What If. If your cells suddenly lost the power to divide, how long would you survive? How dangerous is it, really, to be in a swimming pool in a thunderstorm? If we hooked turbines to people exercising in gyms, how much power could we produce? What if everyone only had one soulmate?When (if ever) did the sun go down on the British empire? How fast can you hit a speed bump while driving and live?What would happen if the moon went away?In pursuit of answers, Munroe runs computer simulations, pores over stacks of declassified military research memos, solves differential equations, and consults with nuclear reactor operators. His responses are masterpieces of clarity and hilarity, studded with memorable cartoons and infographics. They often predict the complete annihilation of humankind, or at least a really big explosion. Far more than a book for geeks, WHAT IF: Serious Scientific Answers to Absurd Hypothetical Questions explains the laws of science in operation in a way that every intelligent reader will enjoy and feel much the smarter for having read.

    Cheng is a mathematician, so she knows how to make an airtight argument. But even for her, logic sometimes falls prey to emotion, which is why she still fears flying and eats more cookies than she should. If a mathematician can't be logical, what are we to do? In this book, Cheng reveals the inner workings and limitations of logic, and explains why alogic--for example, emotion--is vital to how we think and communicate. Cheng shows us how to use logic and alogic together to navigate a world awash in bigotry, mansplaining, and manipulative memes. Insightful, useful, and funny, this essential book is for anyone who wants to think more clearly.

    From childhood onward, we learn how big a "portion" is and how sweet is too sweet. We learn to enjoy green vegetables -- or not. But how does this education happen? What are the origins of taste? In First Bite, award-winning food writer Bee Wilson draws on the latest research from food psychologists, neuroscientists, and nutritionists to reveal that our food habits are shaped by a whole host of factors: family and culture, memory and gender, hunger and love. Taking the reader on a journey across the globe, Wilson introduces us to people who can only eat foods of a certain color; prisoners of war whose deepest yearning is for Mom's apple pie; a nine year old anosmia sufferer who has no memory of the flavor of her mother's cooking; toddlers who will eat nothing but hotdogs and grilled cheese sandwiches; and researchers and doctors who have pioneered new and effective ways to persuade children to try new vegetables. Wilson examines why the Japanese eat so healthily, whereas the vast majority of teenage boys in Kuwait have a weight problem -- and what these facts can tell Americans about how to eat better. The way we learn to eat holds the key to why food has gone so disastrously wrong for so many people. But Wilson also shows that both adults and children have immense potential for learning new, healthy eating habits. An exploration of the extraordinary and surprising origins of our tastes and eating habits, First Bite also shows us how we can change our palates to lead healthier, happier lives.

    She finds that you cannot immunize your child, or yourself, from the world.In this bold, fascinating book, Biss investigates the metaphors and myths surrounding our conception of immunity and its implications for the individual and the social body. As she hears more and more fears about vaccines, Biss researches what they mean for her own child, her immediate community, America, and the world, both historically and in the present moment. She extends a conversation with other mothers to meditations on Voltaire's Candide, Bram Stoker's Dracula, Rachel Carson's Silent Spring, Susan Sontag's AIDS and Its Metaphors, and beyond.On Immunity is a moving account of how we are all interconnected-our bodies and our fates.