Conventional wisdom may be wrong. In this controversial book, the eminent biologist Paul W. Ewald offers some startling arguments:-Germs appear to be at the root of heart disease, Alzheimer’s, schizophrenia, many forms of cancer, and other chronic diseases.-The greatest threats to our health come not from sensational killers such as Ebola, West Nile virus, and super-virulent strains of influenza, but from agents that are already here causing long-term infections, which eventually lead to debilitation and death. -The medical establishment has largely ignored the evidence that implicates these germs, to the detriment of our public health.-New evolutionary theories are available, which explain how germs function and offer opportunities for controlling these modern plagues — if we are willing to listen to them.Plague Time is an eye-opening exploration of the revolutionary new understanding of disease that may set the course of medical research for the twenty-first century.

    is the first deep-dive investigation of a hazardous and illicit industry that has created a worldwide epidemic, ravaging communities and overwhelming and confounding government agencies that are challenged to combat it. "A whole new crop of chemicals is radically changing the recreational drug landscape," writes Ben Westhoff. "These are known as Novel Psychoactive Substances (NPS) and they include replacements for known drugs like heroin, cocaine, ecstasy, and marijuana. They are synthetic, made in a laboratory, and are much more potent than traditional drugs"--and all-too-often tragically lethal. Drugs like fentanyl, K2, and Spice--and those with arcane acronyms like 25i-NBOMe-- were all originally conceived in legitimate laboratories for proper scientific and medicinal purposes. Their formulas were then hijacked and manufactured by rogue chemists, largely in China, who change their molecular structures to stay ahead of the law, making the drugs' effects impossible to predict. Westhoff has infiltrated this shadowy world, becoming the first journalist to report from inside an illicit Chinese fentanyls lab and providing startling and original reporting on how China's vast chemical industry operates, and how the Chinese government subsidizes it. He tracks down the little-known scientists who invented these drugs and inadvertently killed thousands, as well as a mysterious drug baron who turned the law upside down in his home country of New Zealand. Poignantly, Westhoff chronicles the lives of addicted users and dealers, families of victims, law enforcement officers, and underground drug awareness organizers in the U.S. and Europe. Together they represent the shocking and riveting full anatomy of a calamity we are just beginning to understand. From its depths, as Westhoff relates, are emerging new strategies that may provide essential long-term solutions to the drug crisis that has affected so many.

    We like to imagine that it’s based on evidence and the results of fair tests. In reality, those tests are often profoundly flawed. We like to imagine that doctors are familiar with the research literature surrounding a drug, when in reality much of the research is hidden from them by drug companies. We like to imagine that doctors are impartially educated, when in reality much of their education is funded by industry. We like to imagine that regulators let only effective drugs onto the market, when in reality they approve hopeless drugs, with data on side effects casually withheld from doctors and patients.All these problems have been protected from public scrutiny because they’re too complex to capture in a sound bite. But Dr. Ben Goldacre shows that the true scale of this murderous disaster fully reveals itself only when the details are untangled. He believes we should all be able to understand precisely how data manipulation works and how research misconduct on a global scale affects us. In his own words, “the tricks and distortions documented in these pages are beautiful, intricate, and fascinating in their details.” With Goldacre’s characteristic flair and a forensic attention to detail, Bad Pharma reveals a shockingly broken system and calls for something to be done. This is the pharmaceutical industry as it has never been seen before.

    Anthony Fauci a household name, he played a pivotal role in American medicine for over 50 years, as a physician trained in the crucible of medical crisis and an effective researcher who supported medical breakthroughs. Get to know the man behind the sobering and stabilizing presence on TV, and hear the fascinating personal history that equipped him to keep our nation informed about COVID-19.In the summer of 2019, Alan Alda, the acclaimed actor, author and host of the podcast, Clear+Vivid, interviewed Dr. Fauci for the upcoming audio Soldiers of Science. This Audible Original explores a little-known Vietnam-era program that brought the very best and brightest young doctors into government service. Dr. Fauci was one of an elite corps of medical school graduates whose time as clinical researchers at the National Institutes of Health paved the way for life-saving breakthroughs in heart disease, cancer, immunology and the AIDS crisis, not to mention nine Nobel-prize winning discoveries in science (at last count).While editing the full documentary, Alan and the team found themselves deeply moved by Dr. Fauci’s commitment to service, his recollections of his early days at the NIH, and how he coped with the tragedy of the AIDS pandemic. We want our listeners to feel the same sense of inspiration, hope, and the comfort of Dr. Fauci’s insights, so we put together this special preview of Soldiers of Science, highlighting Dr. Fauci’s history. Please enjoy this special excerpt as our salute to all the doctors, nurses, health professionals, first responders, and scientists on the frontlines of the coronavirus pandemic. Soldiers of Science, we thank you for your service.Photo Credit: NIAID©2020 Audible Originals, LLC (P)2020 Audible, Inc.

    Saxons, Vikings, and Celts, which resulted from a systematic ten-year DNA survey of more than 10,000 volunteers, traces the true genetic makeup of the British Isles and its descendants, taking readers from the Pontnewydd cave in North Wales to the resting place of "The Red Lady" of Paviland and the tomb of King Arthur. Genealogy has become a popular pastime of Americans interested in their heritage, and this is the perfect work for anyone interested in finding their heritage in England, Scotland, or Ireland.

    He has a rushing headache and the whites of his eyes look like lemons. He will likely die within days.Here is the true story of how four Americans and one Cuban tracked down a killer, one of the word's most vicious plagues: yellow fever. Set in fever-stricken Cuba, the reader feels the heavy air, smell the stench of disease, hear the whine of mosquitoes biting human volunteers during the surreal experiments. Exploring themes of courage, cooperation, and the ethics of human experimentation, this gripping account is ultimately a story of the triumph of science.

    In this engaging and well-researched book, the trajectory of the plague’s march west across Eurasia and the cause of the great pandemic is thoroughly explored. Inside you will read about... ✓ What was the Black Death? ✓ A Short History of Pandemics ✓ Chronology & Trajectory ✓ Causes & Pathology ✓ Medieval Theories & Disease Control ✓ Black Death in Medieval Culture ✓ Consequences Fascinating insights into the medieval mind’s perception of the disease and examinations of contemporary accounts give a complete picture of what the world’s most effective killer meant to medieval society in particular and humanity in general.

    He guides us from the building of Stonehenge to the founding of the two great glories of medieval England: common law and the cathedrals. He shows us glimpses of the country's most distant past--a Neolithic stirrup found in a grave, a Roman fort, a Saxon tomb, a medieval manor house--and describes in rich prose the successive waves of invaders who made England English, despite being themselves Roman, Viking, Saxon, or Norman French.With his extraordinary skill for evoking time and place and his acute eye for the telling detail, Ackroyd recounts the story of warring kings, of civil strife, and foreign wars. But he also gives us a vivid sense of how England's early people lived: the homes they built, the clothes the wore, the food they ate, even the jokes they told. All are brought vividly to life through the narrative mastery of one of Britain's finest writers.

    Organized conceptually around the major fields of medical endeavour - anatomy, physiology, pathology, pharmacology, surgery, obstetrics, psychiatry, pediatrics, and family medicine - this book is an accessible overview of medical history as a vibrant component of social, intellectual, and cultural history, and as a research discipline in its own right.Each chapter begins in antiquity and ends in the twentieth century. Throughout, Duffin shows that alternative interpretations can be found for most elements of our past and that topics of interest can go well beyond 'great men' and 'great discoveries' to include ideas, diseases, patients, institutions, and great mistakes. This approach does not mean that the 'great men' (and women) are neglected; rather they appear in context. Medical disasters such as chloramphenicol and thalidomide, are covered along with the triumphs, and examples from Canada's past, largely ignored in other medical histories, are included. A chapter on methodology, suggestions for further reading with special attention to Canadian sources, and a careful index make it possible to research a specific event or historical debate, or to satisfy a more general curiosity.By presenting the material in a structure that resonates with the broad outlines of medical training, and by focusing on the questions asked most often, this text is a relevant guide for students to the history of the profession they are about to embrace, and for those who would teach them, be they physicians or historians. Duffin's clear and entertaining prose and the many illustrations will help to demystify medicine for general readers and for students in other domains, such as history, philosophy, and sociology.

    This far-reaching discussion considers mortality from the personal and the universal perspective, generously citing past and present poets and physicians from a diverse and telling range of traditions. Mims, who for two decades served as Professor of Microbiology at London's Guys Hospital, brings a humane, inquisitive, and learned sensibility to his topic. "This book is a light-hearted but wide-ranging survey of death, the causes of death, and the disposal of corpses," writes Mims. "It tells why we die and how we die, and what happens to the dead body and its bits and pieces. It describes the ways corpses are dealt with in different religions and in different parts of the world; the methods for preserving bodies; and the ways--fascinating in their diversity--in which corpses or parts of corpses are used and abused." The volume also explores such crucial death-based notions as the afterlife, the soul, and the prospect of immortality. By way of the book's main focus, Mims continues: "We should take a more matter-of-fact view of death [and] accept it and talk about it more than we do--as we have done with the once taboo subject of sex." This is a work that any student of social anthropology will find equally enlightening and essential.

    His wife, Marguerite, has accused squire Jacques Le Gris of rape. A deadlocked court decrees a “trial by combat” between the two men that also leaves Marguerite’s fate in the balance. For if her husband loses the duel, she will be put to death as a false accuser. While enemy troops pillage the land, and rebellion and plague threaten the lives of all, Carrouges and Le Gris meet in full armor on a walled field in Paris. What follows is a fierce duel, the final one sanctioned by governing powers, before a massive crowd that includes the teenage King Charles VI, during which both combatants are wounded—but only one fatally.Based on extensive research in Normandy and Paris, THE LAST DUEL brings to life a colorful, turbulent age and three unforgettable characters caught in a fatal triangle of crime, scandal, and revenge. THE LAST DUEL is at once a moving human drama, a captivating true crime story, and an engrossing work of historical intrigue with themes that echo powerfully centuries later.

    In the early eighteenth century, the Pirate Republic was home to some of the great pirate captains, including Blackbeard, "Black Sam" Bellamy, and Charles Vane. Along with their fellow pirates—former sailors, indentured servants, and runaway slaves—this "Flying Gang" established a crude but distinctive democracy in the Bahamas, carving out their own zone of freedom in which servants were free, blacks could be equal citizens, and leaders were chosen or deposed by a vote. They cut off trade routes, sacked slave ships, and severed Europe from its New World empires, and for a brief, glorious period the Republic was a success.

    As Tom Standage relates with authority and charm, six of them have had a surprisingly pervasive influence on the course of history, becoming the defining drink during a pivotal historical period. A History of the World in 6 Glasses tells the story of humanity from the Stone Age to the 21st century through the lens of beer, wine, spirits, coffee, tea, and cola. Beer was first made in the Fertile Crescent and by 3000 B.C.E. was so important to Mesopotamia and Egypt that it was used to pay wages. In ancient Greece wine became the main export of her vast seaborne trade, helping spread Greek culture abroad. Spirits such as brandy and rum fueled the Age of Exploration, fortifying seamen on long voyages and oiling the pernicious slave trade. Although coffee originated in the Arab world, it stoked revolutionary thought in Europe during the Age of Reason, when coffeehouses became centers of intellectual exchange. And hundreds of years after the Chinese began drinking tea, it became especially popular in Britain, with far-reaching effects on British foreign policy. Finally, though carbonated drinks were invented in 18th-century Europe they became a 20th-century phenomenon, and Coca-Cola in particular is the leading symbol of globalization.For Tom Standage, each drink is a kind of technology, a catalyst for advancing culture by which he demonstrates the intricate interplay of different civilizations. You may never look at your favorite drink the same way again.

    It’s a fly-on-the-wall account of the titanic fight to pass a 961-page law aimed at fixing America’s largest, most dysfunctional industry. It’s a penetrating chronicle of how the profiteering that Brill first identified in his trailblazing Time magazine cover story continues, despite Obamacare. And it is the first complete, inside account of how President Obama persevered to push through the law, but then failed to deal with the staff incompetence and turf wars that crippled its implementation.   But by chance America’s Bitter Pill ends up being much more—because as Brill was completing this book, he had to undergo urgent open-heart surgery. Thus, this also becomes the story of how one patient who thinks he knows everything about healthcare “policy” rethinks it from a hospital gurney—and combines that insight with his brilliant reporting. The result: a surprising new vision of how we can fix American healthcare so that it stops draining the bank accounts of our families and our businesses, and the federal treasury. Praise for America’s Bitter Pill   “A tour de force . . . a comprehensive and suitably furious guide to the political landscape of American healthcare . . . persuasive, shocking.”—The New York Times   “An energetic, picaresque, narrative explanation of much of what has happened in the last seven years of health policy . . . [Brill] has pulled off something extraordinary.” —The New York Times Book Review   “A thunderous indictment of what Brill refers to as the ‘toxicity of our profiteer-dominated healthcare system.’ ”—Los Angeles Times  “A sweeping and spirited new book [that] chronicles the surprisingly juicy tale of reform.”—The Daily Beast  “One of the most important books of our time.”—Walter Isaacson   “Superb . . . Brill has achieved the seemingly impossible—written an exciting book about the American health system.”—The New York Review of Books

    That book was the last surviving manuscript of an ancient Roman philosophical epic, On the Nature of Things, by Lucretius—a beautiful poem of the most dangerous ideas: that the universe functioned without the aid of gods, that religious fear was damaging to human life, and that matter was made up of very small particles in eternal motion, colliding and swerving in new directions.The copying and translation of this ancient book—the greatest discovery of the greatest book-hunter of his age—fueled the Renaissance, inspiring artists such as Botticelli and thinkers such as Giordano Bruno; shaped the thought of Galileo and Freud, Darwin and Einstein; and had a revolutionary influence on writers such as Montaigne and Shakespeare and even Thomas Jefferson.