How did the human mind--and the uniquely human ability to devise and transmit culture--evolve from its roots in animal behavior? Darwin's Unfinished Symphony presents a captivating new theory of human cognitive evolution. This compelling and accessible book reveals how culture is not just the magnificent end product of an evolutionary process that produced a species unlike all others--it is also the key driving force behind that process.Kevin Laland shows how the learned and socially transmitted activities of our ancestors shaped our intellects through accelerating cycles of evolutionary feedback. The truly unique characteristics of our species--such as our intelligence, language, teaching, and cooperation--are not adaptive responses to predators, disease, or other external conditions. Rather, humans are creatures of their own making. Drawing on his own groundbreaking research, and bringing it to life with vivid natural history, Laland explains how animals imitate, innovate, and have remarkable traditions of their own. He traces our rise from scavenger apes in prehistory to modern humans able to design iPhones, dance the tango, and send astronauts into space.This book tells the story of the painstaking fieldwork, the key experiments, the false leads, and the stunning scientific breakthroughs that led to this new understanding of how culture transformed human evolution. It is the story of how Darwin's intellectual descendants picked up where he left off and took up the challenge of providing a scientific account of the evolution of the human mind.

    In an earlier book, Almost Like A Whale, he took on the extraordinary task of updating The Origin of Species, which he described as the “most original book of the millennium”. His latest book, Coral, follows once more in the footsteps of Darwin, who also wrote a detailed study of coral reefs.For a book with such a humble title, Coral covers a lot of ground, including Captain Cook’s bones; French nuclear tests; in-vitro fertilization; the De Beers’ diamond cartel; color blindness; chaos; immortality; and, of course, Charles Darwin himself. In the hands of a lesser author, such a seemingly disparate range of topics would result in a disjointed and rambling mess. But Jones weaves them around his theme to create a coherent and well-formed whole.Jones explores what coral can teach us about life on Earth, from the survival and decline of species to the role of cooperation in inter-species relationships. Drawing not only on biology, but also on history, politics, literature, economics and mythology, he leads the reader on a wide-ranging and always interesting exploration.He adds that if you have never visited a coral reef, now might be a good time. The book is subtitled A Pessimist in Paradise, and Jones foresees a grim future for the world’s reefs. Today, less than one fifth are protected. He argues that “greenhouse gases have proved impossible to control and marine pollution has been almost as intractable”. The decline of the world’s reefs has already begun and within about fifty years, Jones believes that many more will be gone.Jones is one of the best popularizers of science writing today and this book matches the high standards set by his earlier work. Despite the deeply pessimistic message, at times he still manages to elicit an almost Carl Sagan-esque sense of awe about the natural world.The threat to coral reefs from global warming and damage caused by agricultural runoff have become common topics of media reports. Yet, no matter how much you think you know about coral and coral reefs, you will learn plenty more from this book. (COSMOS Magazine)

    The first small cities formed not only the cradle of civilization, but the spawning ground for the earliest viral epidemics, the first opportunity for viruses to find a home in the human herd. This is a story of fear and ignorance, as everything from demons and the wrath of the gods to minority groups have been blamed for epidemics from smallpox to yellow fever to AIDS. It is a story of grief and heartbreak, as hundreds of thousands, sometimes millions, are wiped out in a single year. And it is a story of great bravery and sacrifice, as doctors and nurses put themselves in harm's way to combat yellow fever in Memphis and Ebola in Zaire, and as researchers risk their own lives to test theories of vaccines and the transmission of disease. Now, in Viruses, Plagues, and History, Michael B. A. Oldstone tells all these stories as he illuminates the history of the devastating diseases that have tormented humanity.Oldstone focuses his tale on a few of the most famous viruses humanity has battled, beginning with some we have effectively defeated, such as smallpox, polio, and measles. Nearly 300 million people were killed by smallpox in this century alone -- more than were killed in all the wars of the twentieth century combined. The author presents a vivid account of the long campaign against the virus, the insightful work of Edward Jenner, who created the smallpox vaccine from cowpox virus in 1796, and the monumental efforts of D. A. Henderson and an army of W.H.O. health care workers to finally eradicate smallpox. The smallpox virus remains the only organism that we have deliberately pushed to complete extinction in the wild.Oldstone then describes the fascinating viruses that have captured headlines in more recent years: Ebola and other hemorrhagic fevers, which literally turn their victims' organs to a bloody pulp; the Hantavirus outbreaks in the southwestern United States and elsewhere; mad cow disease, a frightening illness made worse by government mishandling and secrecy; and, of course, AIDS, often called the plague of our time. And he tells us of the many scientists watching and waiting even now for the next great plague, monitoring influenza strains to see whether the deadly variant from 1918 -- a viral strain that killed over 20 million people in 1918-1919, more than twice the military and civilian casualties of the First World War -- will make a comeback.Viruses have enormous power. They have wiped out cities, brought down dynasties, and helped destroy civilizations. But, as Michael Oldstone reveals, scientific research has given us the power to tame many of these viruses as well. Viruses, Plagues, and History shows us the panorama of humanity's long-standing conflict with our unseen viral enemies, from our successes to our continuing struggles. Oldstone's book is a vivid history of a fascinating field, and a highly reliable dispatch from a worker on the frontiers of this ongoing campaign.

    Nature’s many innovations—some uncannily perfect—call for natural principles that accelerate life’s ability to innovate.”Darwin’s theory of natural selection explains how useful adaptations are preserved over time. But the biggest mystery about evolution eluded him. As genetics pioneer Hugo de Vries put it, “natural selection may explain the survival of the fittest, but it cannot explain the arrival of the fittest.”Can random mutations over a mere 3.8 billion years really be responsible for wings, eyeballs, knees, camouflage, lactose digestion, photosynthesis, and the rest of nature’s creative marvels? And if the answer is no, what is the mechanism that explains evolution’s speed and efficiency?In Arrival of the Fittest, renowned evolutionary biologist Andreas Wagner draws on over fifteen years of research to present the missing piece in Darwin's theory. Using experimental and computational technologies that were heretofore unimagined, he has found that adaptations are not just driven by chance, but by a set of laws that allow nature to discover new molecules and mechanisms in a fraction of the time that random variation would take.Consider the Arctic cod, a fish that lives and thrives within six degrees of the North Pole, in waters that regularly fall below 0 degrees. At that temperature, the internal fluids of most organisms turn into ice crystals. And yet, the arctic cod survives by producing proteins that lower the freezing temperature of its body fluids, much like antifreeze does for a car’s engine coolant. The invention of those proteins is an archetypal example of nature’s enormous powers of creativity. Meticulously researched, carefully argued, evocatively written, and full of fascinating examples from the animal kingdom, Arrival of the Fittest offers up the final puzzle piece in the mystery of life’s rich diversity.

    student, worked on a wartime project in microbiology professor Selman Waksman's lab, searching for an antibiotic to fight infections on the front lines and at home. In his eleventh experiment on a common bacterium found in farmyard soil, Schatz discovered streptomycin, the first effective cure for tuberculosis, one of the world's deadliest diseases.As director of Schatz's research, Waksman took credit for the discovery, belittled Schatz's work, and secretly enriched himself with royalties from the streptomycin patent filed by the pharmaceutical company Merck. In an unprecedented lawsuit, young Schatz sued Waksman, and was awarded the title of "co-discoverer" and a share of the royalties. But two years later, Professor Waksman alone was awarded the Nobel Prize. Schatz disappeared into academic obscurity.For the first time, acclaimed author and journalist Peter Pringle unravels the intrigues behind one of the most important discoveries in the history of medicine. The story unfolds on a tiny college campus in New Jersey, but its repercussions spread worldwide. The streptomycin patent was a breakthrough for the drug companies, overturning patent limits on products of nature and paving the way for today's biotech world. As dozens more antibiotics were found, many from the same family as streptomycin, the drug companies created oligopolies and reaped big profits. Pringle uses firsthand accounts and archives in the United States and Europe to reveal the intensely human story behind the discovery that started a revolution in the treatment of infectious diseases and shaped the future of Big Pharma.

    Prosek travels the globe to tell the story of the eel--from New York to New Zealand; from Europe to Japan and the small island of Pohnpei in Micronesia, where freshwater eels are worshipped by members of the eel clan.

    As a result, antibiotic resistance now ranks among the gravest medical problems of modern times. Good Germs, Bad Germs addresses not only this issue but also what has become known as the "hygiene hypothesis"-- an argument that links the over-sanitation of modern life to now-epidemic increases in immune and other disorders. In telling the story of what went terribly wrong in our war on germs, Jessica Snyder Sachs explores our emerging understanding of the symbiotic relationship between the human body and its resident microbes--which outnumber its human cells by a factor of nine to one! The book also offers a hopeful look into a future in which antibiotics will be designed and used more wisely, and beyond that, to a day when we may replace antibacterial drugs and cleansers with bacterial ones--each custom-designed for maximum health benefits.

    If animals could talk, we would ask them to recall their own ancestries, in particular the secrets as to how they avoided almost inevitable annihilation in the face of daily assaults by predators, climactic cataclysms, deadly infections and innate diseases.In Tears of the Cheetah, medical geneticist and conservationist Stephen J. O'Brien narrates fast-moving science adventure stories that explore the mysteries of survival among the earth's most endangered and beloved wildlife. Here we uncover the secret histories of exotic species such as Indonesian orangutans, humpback whales, and the imperiled cheetah-the world's fastest animal which nonetheless cannot escape its own genetic weaknesses.Among these genetic detective stories we also discover how the Serengeti lions have lived with FIV (the feline version of HIV), where giant pandas really come from, how bold genetic action pulled the Florida panther from the edge of extinction, how the survivors of the medieval Black Death passed on a genetic gift to their descendents, and how mapping the genome of the domestic cat solved a murder case in Canada.With each riveting account of animal resilience and adaptation, a remarkable parallel in human medicine is drawn, adding yet another rationale for species conservation-mining their genomes for cures to our own fatal diseases. Tears of the Cheetah offers a fascinating glimpse of the insight gained when geneticists venutre into the wild.

    The word conjures up images of horrific diseases sweeping the globe and killing everyone in their path. But such highly lethal illnesses almost never create pandemics. The reality is deadly serious but far more subtle.In Pandemics: What Everyone Needs to Know�, Peter Doherty, who won the Nobel Prize for his work on how the immune system recognizes virus-infected cells, offers an essential guide to one of the truly life-or-death issues of our age. In concise, question-and-answer format, he explains the causes of pandemics, how they can be counteracted with vaccines and drugs, and how we can better prepare for them in the future. Doherty notes that the term "pandemic" refers not to a disease's severity but to its ability to spread rapidly over a wide geographical area. Extremely lethal pathogens are usually quickly identified and confined. Nevertheless, the rise of high-speed transportation networks and the globalization of trade and travel have radically accelerated the spread of diseases. A traveler from Africa arrived in New York in 1999 carrying the West Nile virus; one mosquito bite later, it was loose in the ecosystem. Doherty explains how the main threat of a pandemic comes from respiratory viruses, such as influenza and SARS, which disseminate with incredible speed through air travel. The climate disruptions of global warming, rising population density, and growing antibiotic resistance all complicate efforts to control pandemics. But Doherty stresses that pandemics can be fought effectively. Often simple health practices, especially in hospitals, can help enormously. And research into the animal reservoirs of pathogens, from SARS in bats to HIV in chimpanzees, show promise for our prevention efforts.Calm, clear, and authoritative, Peter Doherty's Pandemics is one of the most critically important additions to the What Everyone Needs to Know� series.What Everyone Needs to Know� is a registered trademark of Oxford University Press.

    Stringer's new theory, based on archeological and genetic evidence, holds that distinct humans coexisted and competed across the African continent—exchanging genes, tools, and behavioral strategies.Stringer draws on analyses of old and new fossils from around the world, DNA studies of Neanderthals (using the full genome map) and other species, and recent archeological digs to unveil his new theory. He shows how the most sensational recent fossil findings fit with his model, and he questions previous concepts (including his own) of modernity and how it evolved.Lone Survivors will be the definitive account of who and what we were, and will change perceptions about our origins and about what it means to be human.

    This was the world of medicine when Thomas Dent Mütter began his trailblazing career as a plastic surgeon in Philadelphia during the middle of the nineteenth century.Although he died at just forty-eight, Mütter was an audacious medical innovator who pioneered the use of ether as anesthesia, the sterilization of surgical tools, and a compassion-based vision for helping the severely deformed, which clashed spectacularly with the sentiments of his time.   Brilliant, outspoken, and brazenly handsome, Mütter was flamboyant in every aspect of his life. He wore pink silk suits to perform surgery, added an umlaut to his last name just because he could, and amassed an immense collection of medical oddities that would later form the basis of Philadelphia’s Mütter Museum. Cristin O’Keefe Aptowicz chronicles how Mütter’s efforts helped establish Philadelphia as a global mecca for medical innovation—despite intense resistance from his numerous rivals.

    This fascinating collection of historical curiosities explores some of the strangest cases that have perplexed doctors across the world.From seventeenth-century Holland to Tsarist Russia, from rural Canada to a whaler in the Pacific, many are monuments to human stupidity – such as the sailor who swallowed dozens of penknives to amuse his shipmates, or the chemistry student who in 1850 arrived at a hospital in New York with his penis trapped inside a bottle, having unwisely decided to relieve himself into a vessel containing highly reactive potassium. Others demonstrate exceptional surgical ingenuity long before the advent of anaesthesia – such as a daring nineteenth-century operation to remove a metal fragment from beneath a conscious patient’s heart. We also hear of the weird, often hilarious remedies employed by physicians of yore – from crow’s vomit to port-wine enemas – the hazards of such everyday objects as cucumbers and false teeth, and miraculous recovery from apparently terminal injuries.

    Cave paintings of the giant beasts hint at the profound role they played in early human culture-our Ice Age ancestors built igloo-shaped huts out of mammoth bones and even feasted on mammoth tongues. Eager to uncover more clues to this mystical prehistoric age, explorers since the time of Peter the Great have scoured Siberia for mammoth remains. Now a new generation of explorers has taken to the tundra. Armed with GPS, ground-penetrating radar, and Soviet-era military helicopters, they seek an elusive prize: a mammoth carcass that will help determine how the creature lived, how it died-and how it might be brought back to life.In this adventure-filled narrative, science writer Richard Stone follows two teams of explorers-one Russian/Japanese, the other a French-led consortium-as they battle bitter cold, high winds, supply shortages, and the deeply rooted superstitions of indigenous peoples who fear the consequences of awakening the "rat beneath the ice." Stone travels from St. Petersburg to the Arctic Circle, from the North Sea to high-tech Japanese laboratories, as he traces the sometimes-surreal quest of these intrepid scientists, whose work could well rewrite our planet's evolutionary history. A riveting tale of high-stakes adventure and scientific hubris, Mammoth is also an intellectual voyage through uncharted moral terrain, as we confront the promise and peril of resurrecting creatures from the deep past.

    After 3.8 billion years humankind is about to start evolving by new rules...From leading geopolitical expert and technology futurist Jamie Metzl comes a groundbreaking exploration of the many ways genetic-engineering is shaking the core foundations of our lives -- sex, war, love, and death.At the dawn of the genetics revolution, our DNA is becoming as readable, writable, and hackable as our information technology. But as humanity starts retooling our own genetic code, the choices we make today will be the difference between realizing breathtaking advances in human well-being and descending into a dangerous and potentially deadly genetic arms race.Enter the laboratories where scientists are turning science fiction into reality. Look towards a future where our deepest beliefs, morals, religions, and politics are challenged like never before and the very essence of what it means to be human is at play. When we can engineer our future children, massively extend our lifespans, build life from scratch, and recreate the plant and animal world, should we?

    Gonzalez-Crussi, from the Introduction An international bestseller, translated into eighteen languages, Paul de Kruif’s classic account of the first scientists to see and learn about the microscopic world continues to fascinate new readers. This is a timeless dramatization of the scientists, bacteriologists, doctors, and medical technicians who discovered the microbes and invented the vaccines to counter them. De Kruif writes about how seemingly simple but really fundamental discovers of science—for instance, how a microbe was first viewed in a clear drop of rain water, and when, for the first time, Louis Pasteur discovered that a simple vaccine could save a man from the ravages of rabies by attacking the microbes that cause it.