After World War II, Don's work with the Air Force brought them to Colorado, where their twelve children perfectly spanned the baby boom: the oldest born in 1945, the youngest in 1965. In those years, there was an established script for a family like the Galvins—aspiration, hard work, upward mobility, domestic harmony—and they worked hard to play their parts. But behind the scenes was a different story: psychological breakdown, sudden shocking violence, hidden abuse. By the mid-1970s, six of the ten Galvin boys, one after another, were diagnosed as schizophrenic. How could all this happen to one family?What took place inside the house on Hidden Valley Road was so extraordinary that the Galvins became one of the first families to be studied by the National Institute of Mental Health. Their story offers a shadow history of the science of schizophrenia, from the era of institutionalization, lobotomy, and the schizophrenogenic mother to the search for genetic markers for the disease, always amid profound disagreements about the nature of the illness itself. And unbeknownst to the Galvins, samples of their DNA informed decades of genetic research that continues today, offering paths to treatment, prediction, and even eradication of the disease for future generations.With clarity and compassion, bestselling and award-winning author Robert Kolker uncovers one family's unforgettable legacy of suffering, love, and hope.

    For most of that time, she didn't know why. All of her trips to the ER and her daily anguish, pain, and lethargy only ever resulted in one question: How could any one person be this sick? Several drug addictions, three major hospitalizations, and over $100,000 later, she finally had a diagnosis: late-stage Lyme disease. Sick is Khakpour's arduous, emotional journey—as a woman, a writer, and a lifelong sufferer of undiagnosed health problems—through the chronic illness that perpetually left her a victim of anxiety, living a life stymied by an unknown condition.Divided by settings, Khakpour guides the reader through her illness by way of the locations that changed her course—New York, LA, New Mexico, and Germany—as she meditates on both the physical and psychological impacts of uncertainty, and the eventual challenge of accepting the diagnosis she had searched for over the course of her adult life. With candor and grace, she examines her subsequent struggles with mental illness, her addiction to the benzodiazepines prescribed by her psychiatrists, and her ever-deteriorating physical health. A story about survival, pain, and transformation, Sick is a candid, illuminating narrative of hope and uncertainty, boldly examining the deep impact of illness on one woman's life.

    A vocal cord removed, his throat slashed and stitched together like a bloody boot, the fourteen-year-old boy had not been told that he had cancer and was expected to die.In Stitches, Small, the award-winning children’s illustrator and author, re-creates this terrifying event in a life story that might have been imagined by Kafka. As the images painfully tumble out, one by one, we gain a ringside seat at a gothic family drama where David—a highly anxious yet supremely talented child—all too often became the unwitting object of his parents’ buried frustration and rage.Believing that they were trying to do their best, David’s parents did just the reverse. Edward Small, a Detroit physician, who vented his own anger by hitting a punching bag, was convinced that he could cure his young son’s respiratory problems with heavy doses of radiation, possibly causing David’s cancer. Elizabeth, David’s mother, tyrannically stingy and excessively scolding, ran the Small household under a cone of silence where emotions, especially her own, were hidden.Depicting this coming-of-age story with dazzling, kaleidoscopic images that turn nightmare into fairy tale, Small tells us of his journey from sickly child to cancer patient, to the troubled teen whose risky decision to run away from home at sixteen—with nothing more than the dream of becoming an artist—will resonate as the ultimate survival statemen.

    A modern day fairy tale of New York, Your Voice in My Head is a dazzling and devastating memoir, clear-eyed and shot through with wit. In a voice unlike any other, Emma Forrest explores depression and mania, but also the beauty of love—and the heartbreak of loss.

    It was the pain from that, from feeling ugly, that I always viewed as the great tragedy of my life. The fact that I had cancer seemed minor in comparison.At age nine, Lucy Grealy was diagnosed with a potentially terminal cancer. When she returned to school with a third of her jaw removed, she faced the cruel taunts of classmates. In this strikingly candid memoir, Grealy tells her story of great suffering and remarkable strength without sentimentality and with considerable wit. Vividly portraying the pain of peer rejection and the guilty pleasures of wanting to be special, Grealy captures with unique insight what it is like as a child and young adult to be torn between two warring impulses: to feel that more than anything else we want to be loved for who we are, while wishing desperately and secretly to be perfect.

    So at the age of twelve, Burroughs found himself amidst Victorian squalor living with the doctor’s bizarre family, and befriending a pedophile who resided in the backyard shed. The story of an outlaw childhood where rules were unheard of, and the Christmas tree stayed up all year round, where Valium was consumed like candy, and if things got dull an electroshock- therapy machine could provide entertainment. The funny, harrowing and bestselling account of an ordinary boy’s survival under the most extraordinary circumstances.

     From the moment she uttered the brave and honest words, "I am an alcoholic," to interviewer George Stephanopoulos, Elizabeth Vargas began writing her story, as her experiences were still raw. Now, in Between Breaths, Vargas discusses her accounts of growing up with anxiety--which began suddenly at the age of six when her father served in Vietnam--and how she dealt with this anxiety as she came of age, eventually turning to alcohol for a release from her painful reality. The now-A&E Network reporter reveals how she found herself living in denial about the extent of her addiction, and how she kept her dependency a secret for so long. She addresses her time in rehab, her first year of sobriety, and the guilt she felt as a working mother who could never find the right balance between a career and parenting. Honest and hopeful, Between Breaths is an inspiring read. Winner of the Books for a Better Life Award in the First Book category Instant New York Times and USA Today Bestseller

    In direct, straightforward, and at times strikingly lyrical prose, Jamison looks back at her relationship with her husband, Richard Wyatt, a renowned scientist who battled debilitating dyslexia to become one of the foremost experts on schizophrenia. And with her characteristic honesty, candor, wit, and simplicity, she describes his death, her own long, difficult struggle with grief, and her efforts to distinguish grief from depression.But she also recalls the great joy that Richard brought her during the nearly twenty years they had together. Wryly humorous anecdotes mingle with bittersweet memories of a relationship that was passionate and loving—if troubled on occasion by her manic-depressive (bipolar) illness—as Jamison reveals the ways in which her husband encouraged her to write openly about her mental illness and, through his courage and grace taught her to live fully.A penetrating psychological study of grief viewed from deep inside the experience itself, Nothing Was the Same is also a deeply moving memoir by a superb writer.

    In 1887, 23-year-old reporter Nellie Bly had herself committed to a New York City asylum for 10 days to expose the horrific conditions for 19th-century century mental patients.

    Before Nic became addicted to crystal meth, he was a charming boy, joyous and funny, a varsity athlete and honor student adored by his two younger siblings. After meth, he was a trembling wraith who lied, stole, and lived on the streets. David Sheff traces the first warning signs: the denial, the three a.m. phone calls—is it Nic? the police? the hospital? His preoccupation with Nic became an addiction in itself. But as a journalist, he instinctively researched every treatment that might save his son. And he refused to give up on Nic.

    When a small vial arrives in her mailbox from "Lewis Carroll," Ayelet Waldman is at a low point. Her mood storms have become intolerably severe; she has tried nearly every medication possible; her husband and children are suffering with her. So she opens the vial, places two drops on her tongue, and joins the ranks of an underground but increasingly vocal group of scientists and civilians successfully using therapeutic microdoses of LSD. As Waldman charts her experience over the course of a month--bursts of productivity, sleepless nights, a newfound sense of equanimity--she also explores the history and mythology of LSD, the cutting-edge research into the drug, and the byzantine policies that control it. Drawing on her experience as a federal public defender, and as the mother of teenagers, and her research into the therapeutic value of psychedelics, Waldman has produced a book that is eye-opening, often hilarious, and utterly enthralling.

    Eye-opening and utterly gripping, Koren Zailckas’s story is that of thousands of girls like her who are not alcoholics yet but who routinely use booze as a shortcut to courage and a stand-in for good judgment.With one stiff sip of Southern Comfort at the age of fourteen, Zailckas is initiated into the world of drinking. From then on, she will drink faithfully, fanatically. In high school, her experimentation will lead to a stomach pumping. In college, her excess will give way to a pattern of self-poisoning that will grow more destructive each year. At age twenty-two, Zailckas will wake up in an unfamiliar apartment in New York City, elbow her friend who is passed out next to her, and ask, "Where are we?" Smashed is a sober look at how she got there and, after years of blackouts and smashups, what it took for her to realize she had to stop drinking. Smashed is an astonishing literary debut destined to become a classic.

    Braided with that history is the moving story of Powers's beloved son Kevin--spirited, endearing, and gifted--who triumphed even while suffering from schizophrenia until finally he did not, and the story of his courageous surviving son Dean, who is also schizophrenic.A blend of history, biography, memoir, and current affairs ending with a consideration of where we might go from here, this is a thought-provoking look at a dreaded illness that has long been misunderstood.

    In this hilarious, high-spirited, sometimes harrowing memoir, Shapiro invites us into his battle with cancer, his romance with an oncology nurse, his journey through graduate school, and his most important life lessons. He tells his story with wit and grace and indomitable spirit, showing us that only when the rhythm of life is stirred violently are able to discover its full beauty.

    Leslie Jamison deftly excavates the stories we tell about addiction--both her own and others'--and examines what we want these stories to do, and what happens when they fail us.All the while, she offers a fascinating look at the larger history of the recovery movement, and at the literary and artistic geniuses whose lives and works were shaped by alcoholism and substance dependence, including John Berryman, Jean Rhys, Raymond Carver, Billie Holiday, David Foster Wallace, and Denis Johnson, as well as brilliant figures lost to obscurity but newly illuminated here.For the power of her striking language and the sharpness of her piercing observations, Jamison has been compared to such iconic writers as Joan Didion and Susan Sontag. Yet her utterly singular voice also offers something new. With enormous empathy and wisdom, Jamison has given us nothing less than the story of addiction and recovery in America writ large, a definitive and revelatory account that will resonate for years to come.