But she soon finds herself drawn into the perilous web of Anne's ambition.Desperate to hold onto the king's waning affection, Anne schemes to have him take her guileless young cousin as mistress, ensuring her husband's new paramour will owe her loyalty to the queen. But Margaret has fallen deeply in love with a handsome young courtier. She is faced with a terrible dilemma: give herself to the king and betray the love of her life or refuse to become his mistress and jeopardize the life of the her cousin, Queen Anne.

    In 1474, when most women were almost powerless, twenty-three-year-old Isabella defied a hostile brother and mercurial husband to seize control of Castile and León.Her subsequent feats were legendary. She ended a twenty-four-generation struggle between Muslims and Christians, forcing Moorish invaders back over the Mediterranean Sea. She laid the foundation for a unified Spain. She sponsored Columbus's trip to the Indies and negotiated Spanish control over much of the New World with the help of Rodrigo Borgia, the infamous Pope Alexander VI. She also annihilated all who stood against her by establishing a bloody religious Inquisition that would darken Spain's reputation for centuries.Whether saintly or satanic, no female leader has done more to shape our modern world, where millions of people in two hemispheres speak Spanish and practice Catholicism. Yet history has all but forgotten Isabella's influence, due to hundreds of years of misreporting that often attributed her accomplishments to Ferdinand, the bold and philandering husband she adored.Using new scholarship, Downey's luminous biography tells the story of this brilliant, fervent, forgotten woman, the faith that propelled her through life, and the land of ancient conflicts and intrigue she brought under her command.

    Exploring the family's lineage from the first Stuart king to the last, The Royal Stuarts is a panoramic history of the family that acted as a major player in the Scottish Wars of Independence, the Union of the Crowns, the English Civil War, the Restoration, and more.Drawing on the accounts of historians past and present, novels, and plays, this is the complete story of the Stuart family, documenting their path from the salt marshes of Brittany to the thrones of Scotland and England and eventually to exile. The Royal Stuarts brings to life figures like Mary, Queens of Scots, Charles I, and Bonnie Prince Charlie, uncovering a family of strong affections and fierce rivalries. Told with panache, this is the gripping true story of backstabbing, betrayal, and ambition gone awry.

    The next morning, things take a sharp turn as she’s led from work to the emergency room. By the end of the week, a neurologist delivers a devastating prognosis: Sarah suffered a traumatic brain injury that has caused her IQ to plummet, with no hope of recovery. Her brain has irrevocably changed.Afraid of judgment and deemed no longer fit for work, Sarah isolates herself from the outside world. She spends months at home, with her dogs as her only source of companionship, battling a personality she no longer recognizes and her shock and rage over losing simple functions she’d taken for granted. Her life is consumed by fear and shame until a chance encounter gives Sarah hope that her brain can heal. That conversation lights a small flame of determination, and Sarah begins to push back, painstakingly reteaching herself to read and write, and eventually reentering the workforce and a new, if unpredictable, life.In this highly intimate account of devastation and renewal, Sarah pulls back the curtain on life with traumatic brain injury, an affliction where the wounds are invisible and the lasting effects are often misunderstood. Over years of frustrating setbacks and uncertain triumphs, Sarah comes to terms with her disability and finds love with a woman who helps her embrace a new, accepting sense of self.

    In the early 1800s, women were dying in large numbers from treatable diseases because they avoided receiving medical care. Examinations performed by male doctors were often demeaning and even painful. In addition, women faced stigma from illness—a diagnosis could greatly limit their ability to find husbands, jobs or be received in polite society.Motivated by personal loss and frustration over inadequate medical care, Elizabeth Blackwell, Elizabeth Garrett Anderson and Sophia Jex-Blake fought for a woman’s place in the male-dominated medical field. For the first time ever, Women in White Coats tells the complete history of these three pioneering women who, despite countless obstacles, earned medical degrees and paved the way for other women to do the same. Though very different in personality and circumstance, together these women built women-run hospitals and teaching colleges—creating for the first time medical care for women by women.With gripping storytelling based on extensive research and access to archival documents, Women in White Coats tells the courageous history these women made by becoming doctors, detailing the boundaries they broke of gender and science to reshape how we receive medical care today.

    MacLeod and her husband encountered their dream while vacationing on a remote island in the Scottish Hebrides. Enthralled by its windswept beauty, they soon were the proud owners of a near-derelict croft house--a farmer's stone cottage--on "a small acre" of land. Mary assumed duties as the island's district nurse. Call the Nurse is her account of the enchanted years she and her family spent there, coming to know its folk as both patients and friends.In anecdotes that are by turns funny, sad, moving, and tragic, she recalls them all, the crofters and their laird, the boatmen and tradesmen, young lovers and forbidding churchmen. Against the old-fashioned island culture and the grandeur of mountain and sea unfold indelible stories: a young woman carried through snow for airlift to the hospital; a rescue by boat; the marriage of a gentle giant and the island beauty; a ghostly encounter; the shocking discovery of a woman in chains; the flames of a heather fire at night; an unexploded bomb from World War II; and the joyful, tipsy celebration of a ceilidh. Gaelic fortitude meets a nurse's compassion in these wonderful true stories from rural Scotland.

    Whether it’s the glittering rule of Elizabeth, the ruthless power of her father Henry VIII, or the bloody and radical reign of Mary, the Tudors remain the most fascinating English dynasty. Richard Rex looks at how the public and private lives of the Tudors were inextricably linked, and how each Tudor monarch exuded charisma and danger in equal measure.

    How did one family turn a war-ruined principality into the world’s greatest empire? And how did they lose it all? This is the intimate story of twenty tsars and tsarinas, some touched by genius, some by madness, but all inspired by holy autocracy and imperial ambition. Simon Sebag Montefiore’s gripping chronicle reveals their secret world of unlimited power and ruthless empire-building, overshadowed by palace conspiracy, family rivalries, sexual decadence and wild extravagance, with a global cast of adventurers, courtesans, revolutionaries and poets, from Ivan the Terrible to Tolstoy and Pushkin, to Bismarck, Lincoln, Queen Victoria and Lenin.

    Some of their responses to those outbreaks are almost too strange to believe in hindsight. Get Well Soon delivers the gruesome, morbid details of some of the worst plagues we’ve suffered as a species, as well as stories of the heroic figures who selflessly fought to ease the suffering of their fellow man. With her signature mix of in-depth research and storytelling, and not a little dark humor, Jennifer Wright explores history’s most gripping and deadly outbreaks, and ultimately looks at the surprising ways they’ve shaped history and humanity for almost as long as anyone can remember.

    It killed more people in twenty-four months than AIDS killed in twenty-four years, more in a year than the Black Death killed in a century. But this was not the Middle Ages, and 1918 marked the first collision of science and epidemic disease. Magisterial in its breadth of perspective and depth of research and now revised to reflect the growing danger of the avian flu, The Great Influenza is ultimately a tale of triumph amid tragedy, which provides us with a precise and sobering model as we confront the epidemics looming on our own horizon.

    Lisa Sanders, author of the monthly New York Times Magazine column "Diagnosis," the inspiration for the hit Fox TV series House, M.D.The experience of being ill can be like waking up in a foreign country. Life, as you formerly knew it, is on hold while you travel through this other world as unknown as it is unexpected. When I see patients in the hospital or in my office who are suddenly, surprisingly ill, what they really want to know is, ‘What is wrong with me?’ They want a road map that will help them manage their new surroundings. The ability to give this unnerving and unfamiliar place a name, to know it–on some level–restores a measure of control, independent of whether or not that diagnosis comes attached to a cure. Because, even today, a diagnosis is frequently all a good doctor has to offer.A healthy young man suddenly loses his memory–making him unable to remember the events of each passing hour. Two patients diagnosed with Lyme disease improve after antibiotic treatment–only to have their symptoms mysteriously return. A young woman lies dying in the ICU–bleeding, jaundiced, incoherent–and none of her doctors know what is killing her. In Every Patient Tells a Story, Dr. Lisa Sanders takes us bedside to witness the process of solving these and other diagnostic dilemmas, providing a firsthand account of the expertise and intuition that lead a doctor to make the right diagnosis.Never in human history have doctors had the knowledge, the tools, and the skills that they have today to diagnose illness and disease. And yet mistakes are made, diagnoses missed, symptoms or tests misunderstood. In this high-tech world of modern medicine, Sanders shows us that knowledge, while essential, is not sufficient to unravel the complexities of illness. She presents an unflinching look inside the detective story that marks nearly every illness–the diagnosis–revealing the combination of uncertainty and intrigue that doctors face when confronting patients who are sick or dying. Through dramatic stories of patients with baffling symptoms, Sanders portrays the absolute necessity and surprising difficulties of getting the patient’s story, the challenges of the physical exam, the pitfalls of doctor-to-doctor communication, the vagaries of tests, and the near calamity of diagnostic errors. In Every Patient Tells a Story, Dr. Sanders chronicles the real-life drama of doctors solving these difficult medical mysteries that not only illustrate the art and science of diagnosis, but often save the patients’ lives.

    What did they have in common? For a while they were crowned in gold, cosseted in silk, and flattered by courtiers. But in the end, they spent long nights in dark prison towers and were marched to the scaffold where they surrendered their heads to the executioner. And they are hardly alone in their undignified demises. Throughout history, royal women have had a distressing way of meeting bad ends—dying of starvation, being burned at the stake, or expiring in childbirth while trying desperately to produce an heir. They always had to be on their toes and all too often even devious plotting, miraculous pregnancies, and selling out their sisters was not enough to keep them from forcible consignment to religious orders. From Cleopatra (suicide by asp), to Princess Caroline (suspiciously poisoned on her coronation day), there's a gory downside to being blue-blooded when you lack a Y chromosome.Kris Waldherr's elegant little book is a chronicle of the trials and tribulations of queens across the ages, a quirky, funny, utterly macabre tribute to the dark side of female empowerment. Over the course of fifty irresistibly illustrated and too-brief lives, Doomed Queens charts centuries of regal backstabbing and intrigue. We meet well-known figures like Catherine of Aragon, whose happy marriage to Henry VIII ended prematurely when it became clear that she was a starter wife—the first of six. And we meet forgotten queens like Amalasuntha, the notoriously literate Ostrogoth princess who overreached politically and was strangled in her bath. While their ends were bleak, these queens did not die without purpose. Their unfortunate lives are colorful cautionary tales for today's would-be power brokers—a legacy of worldly and womanly wisdom gathered one spectacular regal ruin at a time.

    Like when doctors prescribed morphine for crying infants. When snorting skull moss was a cure for a bloody nose. When consuming mail-order tapeworms was a latter-day fad diet. Or when snake oil salesmen peddled strychnine (used in rat poison) as an aphrodisiac in the '60s. Seamlessly combining macabre humor with hard science and compelling storytelling, Quackery is a visually rich and information-packed exploration of history's most outlandish cures, experiments, and scams.A humorous book that delves into some of the wacky but true ways that humans have looked to cure their ills. Leeches, mercury, strychnine, and lobotomies are a few of the topics that explore the lengths society has gone in the search for health.

    Its triumphs and disasters are instantly familiar, from the Norman Conquest to the two world wars, but to fully understand their significance we need to know the whole story.A Short History of England sheds light on all the key individuals and events, bringing them together in an enlightening and engaging account of the country's birth, rise to global prominence and then partial eclipse.

    It is the history of who you are and how you came to be. It is unique to you, as it is to each of the 100 billion modern humans who have ever drawn breath. But it is also our collective story, because in every one of our genomes we each carry the history of our species births, deaths, disease, war, famine, migration, and a lot of sex. Since scientists first read the human genome in 2001, it has been subject to all sorts of claims, counterclaims, and myths. In fact, as Adam Rutherford explains, our genomes should be read not as instruction manuals, but as epic poems. DNA determines far less than we have been led to believe about us as individuals, but vastly more about us as a species. In this captivating journey through the expanding landscape of genetics, Adam Rutherford reveals what our genes now tell us about history, and what history tells us about our genes. From Neanderthals to murder, from redheads to race, dead kings to plague, evolution to epigenetics, this is a demystifying and illuminating new portrait of who we are and how we came to be."