The new edition is thoroughly updated, including most notably a new chapter on innate immunity, a capstone chapter on immune responses in time and space, and many new focus boxes drawing attention to exciting clinical, evolutionary, or experimental connections that help bring the material to life.See what's in the LaunchPad

    You may have tried and failed in the past to make running stick, but never the less you are determined to master it. You may tell yourself that “running is hard”, or “I’m just not a runner”, but the truth is that anybody can learn to run if they have the right approach. You will likely have many questions; “how do I build up my running distance?”, “how do I stay motivated to run?”, “how do I warm up and cool down?”. All of these and more are covered off within the pages of this book along with a step by step guide to building up your running to 60 minutes. There is more to learning how to run than just going out and seeing how far you can go three days a week. Some people will undoubtedly have success with this method, but for most beginner runners it takes a little more guidance and support to truly master the art of running. More and more beginners are deciding to take their first steps and learn how to run. Races are popping up all over the place geared towards beginner runners and it remains one of the most accessible sports around. Learning how to run should be a fun and rewarding experience in itself, not just a means to achieve a goal. Beginner’s Luck is a complete program that teaches you everything you need to build your confidence as a runner. The program itself removes the pressure of having to stick rigidly to a set rate of progress, and instead allows you to progress at your own pace. If you are a beginner runner who would like to learn how to run for up to an hour AND surprise yourself as to how easy it really is, get Beginner’s Luck and start out on your journey today.

    However, despite all of the recent advances in computer vision research, the dream of having a computer interpret an image at the same level as a two-year old remains elusive. Why is computer vision such a challenging problem and what is the current state of the art?Computer Vision: Algorithms and Applications explores the variety of techniques commonly used to analyze and interpret images. It also describes challenging real-world applications where vision is being successfully used, both for specialized applications such as medical imaging, and for fun, consumer-level tasks such as image editing and stitching, which students can apply to their own personal photos and videos.More than just a source of "recipes," this exceptionally authoritative and comprehensive textbook/reference also takes a scientific approach to basic vision problems, formulating physical models of the imaging process before inverting them to produce descriptions of a scene. These problems are also analyzed using statistical models and solved using rigorous engineering techniquesTopics and features: Structured to support active curricula and project-oriented courses, with tips in the Introduction for using the book in a variety of customized courses Presents exercises at the end of each chapter with a heavy emphasis on testing algorithms and containing numerous suggestions for small mid-term projects Provides additional material and more detailed mathematical topics in the Appendices, which cover linear algebra, numerical techniques, and Bayesian estimation theory Suggests additional reading at the end of each chapter, including the latest research in each sub-field, in addition to a full Bibliography at the end of the book Supplies supplementary course material for students at the associated website, http: //szeliski.org/Book/ Suitable for an upper-level undergraduate or graduate-level course in computer science or engineering, this textbook focuses on basic techniques that work under real-world conditions and encourages students to push their creative boundaries. Its design and exposition also make it eminently suitable as a unique reference to the fundamental techniques and current research literature in computer vision.

    However, most discussions of Bayesian inference rely on intensely complex mathematical analyses and artificial examples, making it inaccessible to anyone without a strong mathematical background. Now, though, Cameron Davidson-Pilon introduces Bayesian inference from a computational perspective, bridging theory to practice-freeing you to get results using computing power. Bayesian Methods for Hackers illuminates Bayesian inference through probabilistic programming with the powerful PyMC language and the closely related Python tools NumPy, SciPy, and Matplotlib. Using this approach, you can reach effective solutions in small increments, without extensive mathematical intervention. Davidson-Pilon begins by introducing the concepts underlying Bayesian inference, comparing it with other techniques and guiding you through building and training your first Bayesian model. Next, he introduces PyMC through a series of detailed examples and intuitive explanations that have been refined after extensive user feedback. You'll learn how to use the Markov Chain Monte Carlo algorithm, choose appropriate sample sizes and priors, work with loss functions, and apply Bayesian inference in domains ranging from finance to marketing. Once you've mastered these techniques, you'll constantly turn to this guide for the working PyMC code you need to jumpstart future projects. Coverage includes - Learning the Bayesian "state of mind" and its practical implications - Understanding how computers perform Bayesian inference - Using the PyMC Python library to program Bayesian analyses - Building and debugging models with PyMC - Testing your model's "goodness of fit" - Opening the "black box" of the Markov Chain Monte Carlo algorithm to see how and why it works - Leveraging the power of the "Law of Large Numbers" - Mastering key concepts, such as clustering, convergence, autocorrelation, and thinning - Using loss functions to measure an estimate's weaknesses based on your goals and desired outcomes - Selecting appropriate priors and understanding how their influence changes with dataset size - Overcoming the "exploration versus exploitation" dilemma: deciding when "pretty good" is good enough - Using Bayesian inference to improve A/B testing - Solving data science problems when only small amounts of data are available Cameron Davidson-Pilon has worked in many areas of applied mathematics, from the evolutionary dynamics of genes and diseases to stochastic modeling of financial prices. His contributions to the open source community include lifelines, an implementation of survival analysis in Python. Educated at the University of Waterloo and at the Independent University of Moscow, he currently works with the online commerce leader Shopify.

    From Mary, Queen of Scots, trapped by her own code, to the Navajo Code Talkers who helped the Allies win World War II, to the incredible (and incredibly simple) logisitical breakthrough that made Internet commerce secure, The Code Book tells the story of the most powerful intellectual weapon ever known: secrecy.Throughout the text are clear technical and mathematical explanations, and portraits of the remarkable personalities who wrote and broke the world’s most difficult codes. Accessible, compelling, and remarkably far-reaching, this book will forever alter your view of history and what drives it. It will also make you wonder how private that e-mail you just sent really is.

    John's, Antigua; Oranjestad, Aruba; Bridgetown, Barbados; Belize City, Belize; Bermuda; Kralendijk, Bonaire; Calica (Playa del Carmen), Mexico; Cartagena, Colombia; Colon, Panama; Costa Maya, Mexico; Willemstad, Curacao; Roseau, Dominica; Falmouth, Jamaica; Freeport-Lucaya, Bahamas; Grand Cayman, Cayman Islands; Grand Turk, Turks and Caicos Islands; St. George's, Grenada; Pointe-a-Pitre, Guadeloupe; Key West, Florida; La Romana, Dominican Republic; Fort-de-France, Martinique; Montego Bay, Jamaica; Nassau, Bahamas; Charlestown, Nevis; Ocho Rios, Jamaica; Progreso, Mexico; Puerto Limon, Costa Rica; Roatan, Honduras; Samana (Cayo Levantado), Dominican Republic; San Juan, Puerto Rico; Santo Domingo, Domican Republic; Santo Tomas de Castilla, Guatemala; Gustavia, St. Barthelemy; Fredericksted, St. Croix; Cruz Bay, St. John; Basseterre, St. Kitts; Castries, St. Lucia; Philipsburg, St. Maarten; Charlotte Amalie, St. Thomas; Kingstown, St. Vincent; Road Town, Tortola; and The Valley, Virgin Gorda· Covered ports of embarkation: Baltimore, Maryland; Charleston, South Carolina; Fort Lauderdale, Florida; Galveston, Texas; Houston, Texas; Jacksonville, Florida; Miami, Florida; New Orleans, Louisiana; New York, New York; Port Canaveral, Florida; San Juan, Puerto Rico; Tampa, Florida

    Digital technologies—with hardware, software, and networks at their core—will in the near future diagnose diseases more accurately than doctors can, apply enormous data sets to transform retailing, and accomplish many tasks once considered uniquely human.In The Second Machine Age MIT’s Erik Brynjolfsson and Andrew McAfee—two thinkers at the forefront of their field—reveal the forces driving the reinvention of our lives and our economy. As the full impact of digital technologies is felt, we will realize immense bounty in the form of dazzling personal technology, advanced infrastructure, and near-boundless access to the cultural items that enrich our lives.Amid this bounty will also be wrenching change. Professions of all kinds—from lawyers to truck drivers—will be forever upended. Companies will be forced to transform or die. Recent economic indicators reflect this shift: fewer people are working, and wages are falling even as productivity and profits soar.Drawing on years of research and up-to-the-minute trends, Brynjolfsson and McAfee identify the best strategies for survival and offer a new path to prosperity. These include revamping education so that it prepares people for the next economy instead of the last one, designing new collaborations that pair brute processing power with human ingenuity, and embracing policies that make sense in a radically transformed landscape.A fundamentally optimistic book, The Second Machine Age alters how we think about issues of technological, societal, and economic progress.

    In this richly illustrated book, accessible examples are used to show how information theory can be understood in terms of everyday games like '20 Questions', and the simple MatLab programs provided give hands-on experience of information theory in action. Written in a tutorial style, with a comprehensive glossary, this text represents an ideal primer for novices who wish to become familiar with the basic principles of information theory.Download chapter 1 from http://jim-stone.staff.shef.ac.uk/Boo...

    What makes an operating system modern? According to author Andrew Tanenbaum, it is the awareness of high-demand computer applications--primarily in the areas of multimedia, parallel and distributed computing, and security. The development of faster and more advanced hardware has driven progress in software, including enhancements to the operating system. It is one thing to run an old operating system on current hardware, and another to effectively leverage current hardware to best serve modern software applications. If you don't believe it, install Windows 3.0 on a modern PC and try surfing the Internet or burning a CD. Readers familiar with Tanenbaum's previous text, Operating Systems, know the author is a great proponent of simple design and hands-on experimentation. His earlier book came bundled with the source code for an operating system called Minux, a simple variant of Unix and the platform used by Linus Torvalds to develop Linux. Although this book does not come with any source code, he illustrates many of his points with code fragments (C, usually with Unix system calls). The first half of Modern Operating Systems focuses on traditional operating systems concepts: processes, deadlocks, memory management, I/O, and file systems. There is nothing groundbreaking in these early chapters, but all topics are well covered, each including sections on current research and a set of student problems. It is enlightening to read Tanenbaum's explanations of the design decisions made by past operating systems gurus, including his view that additional research on the problem of deadlocks is impractical except for "keeping otherwise unemployed graph theorists off the streets." It is the second half of the book that differentiates itself from older operating systems texts. Here, each chapter describes an element of what constitutes a modern operating system--awareness of multimedia applications, multiple processors, computer networks, and a high level of security. The chapter on multimedia functionality focuses on such features as handling massive files and providing video-on-demand. Included in the discussion on multiprocessor platforms are clustered computers and distributed computing. Finally, the importance of security is discussed--a lively enumeration of the scores of ways operating systems can be vulnerable to attack, from password security to computer viruses and Internet worms. Included at the end of the book are case studies of two popular operating systems: Unix/Linux and Windows 2000. There is a bias toward the Unix/Linux approach, not surprising given the author's experience and academic bent, but this bias does not detract from Tanenbaum's analysis. Both operating systems are dissected, describing how each implements processes, file systems, memory management, and other operating system fundamentals. Tanenbaum's mantra is simple, accessible operating system design. Given that modern operating systems have extensive features, he is forced to reconcile physical size with simplicity. Toward this end, he makes frequent references to the Frederick Brooks classic The Mythical Man-Month for wisdom on managing large, complex software development projects. He finds both Windows 2000 and Unix/Linux guilty of being too complicated--with a particular skewering of Windows 2000 and its "mammoth Win32 API." A primary culprit is the attempt to make operating systems more "user-friendly," which Tanenbaum views as an excuse for bloated code. The solution is to have smart people, the smallest possible team, and well-defined interactions between various operating systems components. Future operating system design will benefit if the advice in this book is taken to heart. --Pete Ostenson

    But the state-of-the-art has moved forward dramatically since Meyers last updated this book in 1997. (For instance, there s now STL. Design patterns. Even new functionality being added through TR1 and Boost.) So Meyers has done a top-to-bottom rewrite, identifying the 55 most valuable techniques you need now to be exceptionally effective with C++. Over half of this edition s content is new. Templates broadly impact C++ development, and you ll find them everywhere. There s extensive coverage of multithreaded systems. There s an entirely new chapter on resource management. You ll find substantial new coverage of exceptions. Much is gained, but nothing s lost: You ll find the same depth of practical insight that first made Effective C++ a classic all those years ago. Bill Camarda, from the July 2005 href="http://www.barnesandnoble.com/newslet... Only

    Proceed step-by-step through five progressively more complex web applications: from a "Hello World" app all the way to a robust Newspaper app with a custom user model, complete user authentication flow, foreign key relationships, and more. Learn current best practices around class-based views, templates, urls, user authentication, testing, and deployment. The material is up-to-date with the latest versions of both Django (2.0) and Python (3.6). TABLE OF CONTENTS: * Introduction * Chapter 1: Initial Setup * Chapter 2: Hello World app * Chapter 3: Pages app * Chapter 4: Message Board app * Chapter 5: Blog app * Chapter 6: Forms * Chapter 7: User Accounts * Chapter 8: Custom User Model * Chapter 9: User Authentication * Chapter 10: Bootstrap * Chapter 11: Password Change and Reset * Chapter 12: Email * Chapter 13: Newspaper app * Chapter 14: Permissions and Authorizations * Chapter 15: Comments * Conclusion

    It was the dawn of a new era in artificial intelligence: a machine capable of beating the reigning human champion at this most cerebral game. That moment was more than a century in the making, and in this breakthrough book, Kasparov reveals his astonishing side of the story for the first time. He describes how it felt to strategize against an implacable, untiring opponent with the whole world watching, and recounts the history of machine intelligence through the microcosm of chess, considered by generations of scientific pioneers to be a key to unlocking the secrets of human and machine cognition. Kasparov uses his unrivaled experience to look into the future of intelligent machines and sees it bright with possibility. As many critics decry artificial intelligence as a menace, particularly to human jobs, Kasparov shows how humanity can rise to new heights with the help of our most extraordinary creations, rather than fear them. Deep Thinking is a tightly argued case for technological progress, from the man who stood at its precipice with his own career at stake.

    The authors present updated coverage of compilers based on research and techniques that have been developed in the field over the past few years. The book provides a thorough introduction to compiler design and covers topics such as context-free grammars, fine state machines, and syntax-directed translation.

    Building on two widely acclaimed previous editions, Craig Larman has updated this book to fully reflect the new UML 2 standard, to help you master the art of object design, and to promote high-impact, iterative, and skillful agile modeling practices.Developers and students will learn object-oriented analysis and design (OOA/D) through three iterations of two cohesive, start-to-finish case studies. These case studies incrementally introduce key skills, essential OO principles and patterns, UML notation, and best practices. You won’t just learn UML diagrams - you’ll learn how to apply UML in the context of OO software development.Drawing on his unsurpassed experience as a mentor and consultant, Larman helps you understand evolutionary requirements and use cases, domain object modeling, responsibility-driven design, essential OO design, layered architectures, “Gang of Four” design patterns, GRASP, iterative methods, an agile approach to the Unified Process (UP), and much more. This edition’s extensive improvements include:- A stronger focus on helping you master OOA/D through case studies that demonstrate key OO principles and patterns, while also applying the UML- New coverage of UML 2, Agile Modeling, Test-Driven Development, and refactoring- Many new tips on combining iterative and evolutionary development with OOA/D- Updates for easier study, including new learning aids and graphics- New college educator teaching resources- Guidance on applying the UP in a light, agile spirit, complementary with other iterative methods such as XP and Scrum- Techniques for applying the UML to documenting architectures- A new chapter on evolutionary requirements, and much moreApplying UML and Patterns, Third Edition, is a lucid and practical introduction to thinking and designing with objects - and creating systems that are well crafted, robust, and maintainable.

    With this book, you'll learn how to load data, assemble and disassemble data objects, navigate R's environment system, write your own functions, and use all of R's programming tools.RStudio Master Instructor Garrett Grolemund not only teaches you how to program, but also shows you how to get more from R than just visualizing and modeling data. You'll gain valuable programming skills and support your work as a data scientist at the same time.Work hands-on with three practical data analysis projects based on casino gamesStore, retrieve, and change data values in your computer's memoryWrite programs and simulations that outperform those written by typical R usersUse R programming tools such as if else statements, for loops, and S3 classesLearn how to write lightning-fast vectorized R codeTake advantage of R's package system and debugging toolsPractice and apply R programming concepts as you learn them