Updated to reflect all critical new developments in drug action and drug-disease interaction. This is the desert island book of all medical pharmacology - if you can own just one pharmacology book, this is it.

    The book examines the cat inside out, starting with a nose-to-tail explanation of how evolution has shaped this perfect little predator. Information on feral, social and age- and breed-related behaviors reveals the biological and behavioral adaptations cats have made over centuries in order to successfully live with humans.The author also reveals what makes a cat content in its daily life, both in the house and out and about in the neighborhood. The author examines troublesome behaviors, such as aggression, toilet-troubles and turf wars, revealing their biological sources and suggesting remedies. There are also tips on the adaptations pet owners can make at home to provide a cat-friendly environment, and 240 full-color photos add romance to the text.For the cat lover who wants to know everything about a beloved pet to the animal lover who is curious about all pets, The Secret Life of Your Cat is a richly illustrated and authoritative guide to the singular mystery that is the cat.

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    It is written to impart a sense of intellectual history of biochemistry, an understanding of the tools and approaches used to solve biochemical puzzles, and a hint of the excitement that accompanies new discoveries. This edition has been thoroughly updated to reflect the most recent advances in biochemistry, particularly in the areas of genomics and structural biology. A new chapter focuses on cytoskeletal and motor proteins, currently one of the most active areas of research in biochemistry.

    Fuzzy brown molds mischievously turn forgotten peaches to slime in the kitchen fruit bowl. And in thousands of other ways, members of the kingdom Fungi do their part to make life on Earth the miracle that it is. In this lively book, George Hudler leads us on a tour of an often-overlooked group of organisms, which differ radically from both animals and plants. Along the way the author stops to ponder the marvels of nature and the impact of mere microbes on the evolution of civilization. Nature's ultimate recyclers not only save us from drowning in a sea of organic waste, but also provide us with food, drink, and a wide array of valuable medicines and industrial chemicals.Some fungi make deadly poisons and psychedelic drugs that have interesting histories in and of themselves, and Hudler weaves tales of those into his scientific account of the nature of the fungi. The role of fungi in the Irish potato famine, in the Salem Witch Trials, in the philosophical writings of Greek scholars, and in the creation of ginger snaps are just a few of the many great moments in history to grace these pages.Hudler moves so easily from discussing human history to exploring scientific knowledge, all with a sense of humor and enthusiasm, that one can well understand why he is an award-winning teacher both at Cornell University as well as nationally. Few, for instance, who read his invitation to get out of your chair and take a short walk will ever again look without curiosity and admiration at the rotten part of the world around them. Magical Mushrooms, Mischievous Molds is full of information that will satisfy history buffs, science enthusiasts, and anyone interested in nature's miracles. Everyone in Hudler's audience will develop a new appreciation of the debt they owe to the molds for such common products as penicillin, wine, and bread.

    Two days later, she got her first glimpse of the famous, terrifying jaws up close and she was instantly hooked; her fascination soon yielded to obsession-and an invitation to return for a full season. But as Casey readied herself for the eight-week stint, she had no way of preparing for what she would find among the dangerous, forgotten islands that have banished every campaign for civilization in the past two hundred years.

    But what accounts for the incredible longevity of dinosaurs? A renowned scientist now provides a startling explanation that is rewriting the history of the Age of Dinosaurs. Dinosaurs were pretty amazing creatures--real-life monsters that have the power to fascinate us. And their fiery Hollywood ending only serves to make the story that much more dramatic. But fossil evidence demonstrates that dinosaurs survived several mass extinctions, and were seemingly unaffected by catastrophes that decimated most other life on Earth. What could explain their uncanny ability to endure through the ages? Biologist and earth scientist Peter Ward now accounts for the remarkable indestructibility of dinosaurs by connecting their unusual respiration system with their ability to adapt to Earth's changing environment--a system that was ultimately bequeathed to their descendants, birds. By tracing the evolutionary path back through time and carefully connecting the dots from birds to dinosaurs, Ward describes the unique form of breathing shared by these two distant relatives and demonstrates how this simple but remarkable characteristic provides the elusive explanation to a question that has thus far stumped scientists. Nothing short of revolutionary in its bold presentation of an astonishing theory, Out of Thin Air is a story of science at the edge of discovery. Ward is an outstanding guide to the process of scientific detection. Audacious and innovative in his thinking, meticulous and thoroughly detailed in his research, only a scientist of his caliber is capable of telling this surprising story.

    Rhythm guitarist with The Rolling Stones for over 30 years, he is also famous in his own right as a solo artist.

    introduced some revolutionary concepts in the game industry. Never before had the D&D rules been used to tell an epic fantasy tale using full-realized pre-generated characters. It was also the first time that roleplaying adventures would match a story being told in fantasy novels on mass-market shelves. Since MWP began publishing DRAGONLANCE game produts for the revised d20 System, the most often-asked question from fans is "When do we get to see the original modules?" By popular demand, we are presenting all-new versions of the classic adventures. The second in the trilogy, Dragons of Winter, continues the epic War of the Lance. The heroes visit the haunted forests of Silvanesti, the landlocked port city of Tarsis, and the mighty stronghold known as the High Clerist's Tower. The adventures are being completely revised, drawing on twenty years of DRAGONLANCE history, incorporating material most recently featured in the Silver Anniversary edition of the adventures. They will include new character statistics featuring the popular Heroes of the Lance.

    Cave paintings of the giant beasts hint at the profound role they played in early human culture-our Ice Age ancestors built igloo-shaped huts out of mammoth bones and even feasted on mammoth tongues. Eager to uncover more clues to this mystical prehistoric age, explorers since the time of Peter the Great have scoured Siberia for mammoth remains. Now a new generation of explorers has taken to the tundra. Armed with GPS, ground-penetrating radar, and Soviet-era military helicopters, they seek an elusive prize: a mammoth carcass that will help determine how the creature lived, how it died-and how it might be brought back to life.In this adventure-filled narrative, science writer Richard Stone follows two teams of explorers-one Russian/Japanese, the other a French-led consortium-as they battle bitter cold, high winds, supply shortages, and the deeply rooted superstitions of indigenous peoples who fear the consequences of awakening the "rat beneath the ice." Stone travels from St. Petersburg to the Arctic Circle, from the North Sea to high-tech Japanese laboratories, as he traces the sometimes-surreal quest of these intrepid scientists, whose work could well rewrite our planet's evolutionary history. A riveting tale of high-stakes adventure and scientific hubris, Mammoth is also an intellectual voyage through uncharted moral terrain, as we confront the promise and peril of resurrecting creatures from the deep past.

    This class-tested and successful textbook synthesizes the established facts of immunology into a comprehensible, coherent, and up-to-date account of how the immune system works, rather than presenting immunology as a chronology of experiments and discoveries. Emphasizing the human immune system the text has been designed to break down the barriers which often divide basic and clinical immunology. The reader-friendly text, section and chapter summaries, and full-color illustrations make the book accessible and easily understandable to students. The Immune System is adapted from Immunobiology by Janeway, Travers & Walport.

    Starting with the band's origins in Oxford, journalist Martin Clarke covers the essential points: Radiohead's breakout single "Creep," the pivotal album OK Computer, Thom Yorke's continuing political and artistic evolution, and the band's future. This revised edition includes a close look at how the band escaped the rock straightjacket with Kid A and Amnesiac , as well as their most recent album, Hail to the Thief . Clark also offers an in-depth examination of the outspoken, mysterious Yorke, offering insight into the personal demons the vocalist has battled throughout his career as Radiohead's frontman. An incisive look at one of the world's most beloved, followed musical acts, Radiohead: Hysterical and Useless provides stimulating coverage of a provocative group.

    Aloha Magnum is a chronicle of Larry Manetti's wild childhood, his crazy days in Hollywood, his moonlighting as a prominent restaurateur, and his escapades with the rich, famous, and equally outrageous.

    She brings her exhaustive knowledge to this groundbreaking manual that covers everything you need to know about the process, including:• The best piercings and placements for various body parts and body types• Terminology, tools, and techniques of the trade• Vital sterility, sanitation, and hygiene information • Jewelry designs, shapes, and materials• Advice for people with stretch marks, plastic surgery, and unique anatomy• Healing, aftercare, and troubleshooting for problem-free piercing"As a piercer, nurse, and educator, I can say without a doubt that this is the most complete book ever written for all people in our industry."--DAVID A. VIDRA, FOUNDER AND PRESIDENT OF HEALTH EDUCATORS, INC."No one is more qualified to write this book than Elayne Angel. With more than three decades of personal experience to her credit, no one knows the subject better."--JIM WARD, FOUNDER OF GAUNTLET, THE WORLD'S FIRST BODY PIERCING STUDIO"This is an exciting book for a field that has exploded in the last two decades. National industry standards are needed, and Elayne provides important data."--MYRNA L. ARMSTRONG, RN, EdD

    A Papua New Guinean elder shoves off in his hand-carved canoe, ready to summon a shark with ancient magic. A scientist finds a rare shark in Indonesia and forges a deal with villagers so it and other species can survive.In this eye-opening adventure that spans the globe, Juliet Eilperin investigates the fascinating ways different individuals and cultures relate to the ocean’s top predator. Along the way, she reminds us why, after millions of years, sharks remain among nature’s most awe-inspiring creatures.From Belize to South Africa, from Shanghai to Bimini, we see that sharks are still the object of an obsession that may eventually lead to their extinction. This is why movie stars and professional athletes go shark hunting in Miami and why shark’s fin soup remains a coveted status symbol in China. Yet we also see glimpses of how people and sharks can exist alongside one another: surfers tolerating their presence off Cape Town and ecotourists swimming with sharks that locals in the Yucatán no longer have to hunt.With a reporter’s instinct for a good story and a scientist’s curiosity, Eilperin offers us an up-close understanding of these extraordinary, mysterious creatures in the most entertaining and illuminating shark encounter you’re likely to find outside a steel cage.