She explores the culture of genealogy buffs, the science of DNA, and the business of companies like Ancestry and 23andMe, all while tracing the story of one woman, her unusual results, and a relentless methodical drive for answers that becomes a thoroughly modern genetic detective story.

                Gut Reactions by chemist Simon Quellen Field shows readers how their bodies react to food and the environment and how their brains affect what and how much they eat. It reveals why some diets work for some people but not for others, based on genetics, previous weight history, brain chemistry, environmental cues, and social pressures. It explores how dozens of hormones affect hunger and satiety and interact with the brain and the gut to regulate feeding behavior. And it explains the addictive nature of foods that interact with the same dopamine and opioid receptors in the brain as cocaine, heroin, amphetamines, and nicotine.             Whether you’re looking to lose weight, put on muscle mass, or simply understand how your metabolism or gut microbiome impact your food cravings, Simon Quellen Field has the scientific answers for you.

    The world knew him as a union official, a long-time member of the Teamsters Union; he was a member of Jimmy Hoffa’s inner circle at the top of the national union. He had run-ins with the law in this position. He was charged with the murder of a rebel union member in a riot that occurred outside the Teamster’s Local Philadelphia Union Hall, but the charges were later dropped. He went to prison in the 80s after being caught on a wire instructing once of his crew to break someone’s legs and was named in Rudy Giuliani’s Mafia Commission Trial as an unindicted co-conspirator and one of only two non-Italian members of the Mafia Commission. As an old man suffering from cancer that would soon kill him, Frank Sheeran shared his story with his attorney. He told him of the things that were already known, but he shared much, much more. This book explores Frank Sheeran’s confessions as a lifelong criminal with ties to some of the biggest crimes of the 20th century. Inside this book, you will find: A detailed account of Frank Sheeran’s time in the army during the second world war, where he was in combat for an astounding four hundred and eleven days, with a focus on the war crimes he has admitted to; A look into Sheeran’s post-war slides into a life of crime, finding himself working for the Mafia before he even knew what the Mafia was; Information on his time as a hitman for the Mafia and how that led him to work for Jimmy Hoffa as muscle and hitman for the powerful Teamster Boss; Frank Sheeran’s accounts of his connections to the Bay of Pigs Invasion and the Assassination of JFK; and His confession to the murders of Crazy Joe Gallo and of his friend, Jimmy Hoffa.

    Nicholas Perricone’s advice, care, and transformative eating plan–and all with the welcome yet unexpected benefit of losing excess weight along with the wrinkles! Building on this discovery, Dr. Perricone breaks new ground with his trademark anti-inflammatory program based on the foods, supplements, and lifestyle changes with the proven ability to accelerate fat loss by increasing metabolism and building and maintaining muscle mass.Consider this staggering fact: As we age, we can expect to gain ten pounds of fat and lose five pounds of muscle each decade. In three easy steps, Dr. Perricone shows how to fight this weight gain and rebuild muscle mass, and avoid the haggard, aging, and drawn appearance that results from other weight-loss programs.Inside The Perricone Weight-Loss Diet discover• the rejuvenating and slimming secrets of the anti-inflammatory diet• which foods, supplements, and lifestyle changes enable us to lose fat while maintaining muscle• how to control hormones such as insulin and cortisol to lose weight • how to maintain youthful, firm, and radiantly toned skin on the face and body during weight lossAs an added bonus, as you follow Dr. Perricone’s program you’ll sleep better, have more energy and less stress, and experience greater mental clarity without the food cravings. Lose the weight, the wrinkles, and the years!

    It is a waste product and a commodity pricier than oil. It can save lives and transmit deadly infections. Each one of us has roughly nine pints of it, yet many don’t even know their own blood type. And for all its ubiquity, the few tablespoons of blood discharged by 800 million women are still regarded as taboo; menstruation is perhaps the single most demonized biological event.Rose George, author of The Big Necessity, is renowned for her intrepid work on topics that are invisible but vitally important. In Nine Pints, she takes us from ancient practices of bloodletting to modern “hemovigilance” teams that track blood-borne diseases. She introduces Janet Vaughan, who set up the world’s first system of mass blood donation during the Blitz, and Arunachalam Muruganantham, known as “Menstrual Man” for his work on sanitary pads for developing countries. She probes the lucrative business of plasma transfusions, in which the U.S. is known as the “OPEC of plasma.” And she looks to the future, as researchers seek to bring synthetic blood to a hospital near you.Spanning science and politics, stories and global epidemics, Nine Pints reveals our life's blood in an entirely new light.

    Yet despite advanced training in cancer genetics and years of practicing medicine, Dr. Theo Ross was never certain whether the history of cancers in her family was simple bad luck or a sign that they were carriers of a cancer-causing genetic mutation. Then she was diagnosed with melanoma, and for someone with a dark complexion, melanoma made no sense. It turned out there was a genetic factor at work.   Using her own family’s story, the latest science of cancer genetics, and her experience as a practicing physician, Ross shows readers how to spot the patterns of inherited cancer, how to get tested for cancer-causing genes, and what to do if you have one. With a foreword by Siddartha Mukherjee, prize winning author of The Emperor of All Maladies, this will be the first authoritative, go-to for people facing inherited cancer, this book empowers readers to face their genetic heritage without fear and to make decisions that will keep them and their families healthy.

    Our memory is unreliable; we can't multiply large sums in our heads; advertising manipulates our judgment; we tend to distrust people who are different from us; supernatural beliefs and superstitions are hard to shake; we prefer instant gratification to long-term gain; and what we presume to be rational decisions are often anything but. Drawing on striking examples and fascinating studies, neuroscientist Dean Buonomano illuminates the causes and consequences of these "bugs" in terms of the brain's innermost workings and their evolutionary purposes. He then goes one step further, examining how our brains function-and malfunction-in the digital, predator-free, information-saturated, special effects-addled world that we have built for ourselves. Along the way, Brain Bugs gives us the tools to hone our cognitive strengths while recognizing our inherent weaknesses.

    But new research from neuroscientists and psychologists suggests that, in fact, the brain reorganizes, improves in important functions, and even helps us adopt a more optimistic outlook in middle age. Growth of white matter and brain connectors allow us to recognize patterns faster, make better judgments, and find unique solutions to problems. Scientists call these traits cognitive expertise and they reach their highest levels in middle age. In her impeccably researched book, science writer Barbara Strauch explores the latest findings that demonstrate, through the use of technology such as brain scans, that the middle-aged brain is more flexible and more capable than previously thought. For the first time, long-term studies show that our view of middle age has been misleading and incomplete. By detailing exactly the normal, healthy brain functions over time, Strauch also explains how its optimal processes can be maintained. Part scientific survey, part how-to guide, "The Secret Life of the Grown-Up Brain" is a fascinating glimpse at our surprisingly talented middle-aged minds."

    In three successive waves, from 1918 to 1919, influenza killed more than 50 million people. German soldiers termed it Blitzkatarrh, British soldiers referred to it as Flanders Grippe, but world-wide, the pandemic gained the notorious title of “Spanish Flu." Nowhere on earth escaped: the United States recorded 550,000 deaths (five times its total military fatalities in the war), while European deaths totaled more than two million.Amid the war, some governments suppressed news of the outbreak. Even as entire battalions were decimated, with both the Allies and the Germans suffering massive casualties, the details of many servicemen’s deaths were hidden to protect public morale. Meanwhile, civilian families were being struck down in their homes. Philadelphia ran out of gravediggers and coffins, and mass burial trenches had to be excavated with steam shovels. Spanish flu conjured up the specter of the Black Death of 1348 and the great plague of 1665, while the medical profession, shattered after five terrible years of conflict, lacked the resources to contain and defeat this new enemy. Through primary and archival sources, historian Catharine Arnold gives readers the first truly global account of this terrible epidemic.

    The hunt for the Higgs was the subject of wide media attention due to the cost of the project, the complexity of the experiment, and the importance of its result. And, when it was announced with great fanfare in 2012 that physicists has succeeded in creating and identifying this all-important new particle, the discovery was celebrated around the world.And yet, virtually no one who read that news could tell you what, exactly, the Higgs boson was, and why its discovery was so important that we had to spend 10 billion dollars and build the single largest and most complex device in the history of mankind in order to find it. When you understand the details, this story ranks as one of the most thrilling in the history of modern science.Award-winning theoretical physicist Sean Carroll, a brilliant researcher as well as a gifted speaker who excels in explaining scientific concepts to the public, is perfectly positioned to tell this story. In this 12-lecture masterpiece of scientific reporting, you'll learn everything you need to know to fully grasp the significance of this discovery, including the basics of quantum mechanics; the four forces that comprise the Standard Model of particle physics; how these forces are transmitted by fields and particles; and the importance of symmetry in physics.You also get an in-depth view of the Large Hadron Collider - the largest machine ever built, and the device responsible for finally revealing the concept of the Higgs boson as reality. By the end, you'll understand how the Higgs boson verifies the final piece in the Standard Model of particle physics, and how its discovery validates and deepens our understanding of the universe.

    She conjures up early operating theaters--no place for the squeamish--and surgeons, working before anesthesia, who were lauded for their speed and brute strength. These medical pioneers knew that the aftermath of surgery was often more dangerous than their patients' afflictions, and they were baffled by the persistent infections that kept mortality rates stubbornly high. At a time when surgery couldn't have been more hazardous, an unlikely figure stepped forward: a young, melancholy Quaker surgeon named Joseph Lister, who would solve the deadly riddle and change the course of history.Fitzharris dramatically recounts Lister's discoveries in gripping detail, culminating in his audacious claim that germs were the source of all infection--and could be countered by antiseptics. Focusing on the tumultuous period from 1850 to 1875, she introduces us to Lister and his contemporaries--some of them brilliant, some outright criminal--and takes us through the grimy medical schools and dreary hospitals where they learned their art, the deadhouses where they studied anatomy, and the graveyards they occasionally ransacked for cadavers.Eerie and illuminating, The Butchering Art celebrates the triumph of a visionary surgeon whose quest to unite science and medicine delivered us into the modern world.

    With the support of elite marathon runner, Mara Yamauchi, and sports psychologist, Dr Josephine Perry, Ant will mentally prepare his recruits for the big day – but is it enough to get them over the finish line?

    The Chronic Cough Enigma is written for people who have been coughing for months or years and cannot get useful answers from their doctors.More than 20 million Americans suffer from what is known as enigmatic chronic cough. This book provides insights from Dr. Jamie Koufman’s almost forty years of successfully managing thousands of long-suffering cough patients. Indeed, the typical chronic cough patient who comes to her office has been coughing for more than a decade. This book provides the many who suffer from chronic cough new and potentially life-changing information and the potential to be cured.

    Learning the skills and techniques of artful reading can improve your life in many ways, whether you're a fiction reader, an aspiring writer, a book club member, or a student.And the best part: These skills are not difficult or unwieldy; rather, they are well within your reach. This entertaining, 24-lecture course gives you a veritable toolbox of knowledge and methods to approach even the most daunting reading experience with increased confidence.You'll learn the definitions and characteristics of terms such as authorship, master plot, and genre. While some of these nuts-and-bolts concepts may be familiar to you, Professor Spurgin examines them from multiple angles, revealing hidden meanings that can escape even experienced readers.Practical tips and techniques will maximize your effectiveness as an artful reader. You'll see why holding an initial reading session will acquaint you with the author's writing style and the characters, making the book easy to return to even if you take a few days off.You'll also discover the benefits of "pre-reading" - exploring a book's organization and structure - and how to constantly ask questions to become more deeply involved with the characters and their stories.Throughout the course, a host of literary "case studies" will refine and elaborate on the concepts of artful reading. Literary examples show how you can finally approach works that, in the past, might have seemed intimidating - making your future reading experiences both more engaging and more enlightening.

    is the first deep-dive investigation of a hazardous and illicit industry that has created a worldwide epidemic, ravaging communities and overwhelming and confounding government agencies that are challenged to combat it. "A whole new crop of chemicals is radically changing the recreational drug landscape," writes Ben Westhoff. "These are known as Novel Psychoactive Substances (NPS) and they include replacements for known drugs like heroin, cocaine, ecstasy, and marijuana. They are synthetic, made in a laboratory, and are much more potent than traditional drugs"--and all-too-often tragically lethal. Drugs like fentanyl, K2, and Spice--and those with arcane acronyms like 25i-NBOMe-- were all originally conceived in legitimate laboratories for proper scientific and medicinal purposes. Their formulas were then hijacked and manufactured by rogue chemists, largely in China, who change their molecular structures to stay ahead of the law, making the drugs' effects impossible to predict. Westhoff has infiltrated this shadowy world, becoming the first journalist to report from inside an illicit Chinese fentanyls lab and providing startling and original reporting on how China's vast chemical industry operates, and how the Chinese government subsidizes it. He tracks down the little-known scientists who invented these drugs and inadvertently killed thousands, as well as a mysterious drug baron who turned the law upside down in his home country of New Zealand. Poignantly, Westhoff chronicles the lives of addicted users and dealers, families of victims, law enforcement officers, and underground drug awareness organizers in the U.S. and Europe. Together they represent the shocking and riveting full anatomy of a calamity we are just beginning to understand. From its depths, as Westhoff relates, are emerging new strategies that may provide essential long-term solutions to the drug crisis that has affected so many.