Phosphorescence: On Awe, Wonder and Things That Sustain You When the World Goes Dark


Julia Baird - 2020
    We know, for example, that there are a few core truths to science of happiness. We know that being kind and altruistic makes us happy, that turning off devices, talking to people, forging relationships, living with meaning and delving into the concerns of others offer our best chance at achieving happiness. But how do we retain happiness? It often slips out of our hands as quickly as we find it. So, when we are exposed to, or learn, good things, how do we continue to burn with them?And more than that, when our world goes dark, when we're overwhelmed by illness or heartbreak, loss or pain, how do we survive, stay alive or even bloom? In the muck and grit of a daily existence full of disappointments and a disturbing lack of control over many of the things that matter most - finite relationships, fragile health, fraying economies, a planet in peril - how do we find, nurture and carry our own inner, living light - a light to ward off the darkness?Absorbing, achingly beautiful, inspiring and deeply moving, Julia Baird has written exactly the book we need for these times.

You Are the Placebo: Making Your Mind Matter


Joe Dispenza - 2014
    In You Are the Placebo, Dr. Joe Dispenza shares numerous documented cases of those who reversed cancer, heart disease, depression, crippling arthritis, and even the tremors of Parkinson’s disease by believing in a placebo. Similarly, Dr. Joe tells of how others have gotten sick and even died the victims of a hex or voodoo curse—or after being misdiagnosed with a fatal illness. Belief can be so strong that pharmaceutical companies use double- and triple-blind randomized studies to try to exclude the power of the mind over the body when evaluating new drugs.     Dr. Joe does more than simply explore the history and the physiology of the placebo effect. He asks the question: “Is it possible to teach the principles of the placebo, and without relying on any external substance, produce the same internal changes in a person’s health and ultimately in his or her life?” Then he shares scientific evidence (including color brain scans) of amazing healings from his workshops, in which participants learn his model of personal transformation, based on practical applications of the so-called placebo effect. The book ends with a “how-to” meditation for changing beliefs and perceptions that hold us back—the first step in healing.     You Are the Placebo combines the latest research in neuroscience, biology, psychology, hypnosis, behavioral conditioning, and quantum physics to demystify the workings of the placebo effect . . . and show how the seemingly impossible can become possible.

She Comes First: The Thinking Man's Guide to Pleasuring a Woman


Ian Kerner - 2004
    The New York Times praises Kerner’s “cool sense of humor and an obsessive desire to inform,” as he “encourages men through an act that many find mystifying.” An indispensable aid to a healthier, more fulfilling sex life for her and him, She Comes First offers techniques and philosophy that have already earned raves from the likes of bestselling author and Loveline co-host Dr. Drew Pinsky as well as Playgirl magazine, which cheers, “Hallelujah!”.

The Idea of the Brain: The Past and Future of Neuroscience


Matthew Cobb - 2020
    Yet, despite the astonishing discoveries of science, we still have only the vaguest idea of how the brain works. In The Idea of the Brain, scientist and historian Matthew Cobb traces how our conception of the brain has evolved over the centuries. Although it might seem to be a story of ever-increasing knowledge of biology, Cobb shows how our ideas about the brain have been shaped by each era's most significant technologies. Today we might think the brain is like a supercomputer. In the past, it has been compared to a telegraph, a telephone exchange, or some kind of hydraulic system. What will we think the brain is like tomorrow, when new technology arises? The result is an essential read for anyone interested in the complex processes that drive science and the forces that have shaped our marvelous brains.

Conscious: A Brief Guide to the Fundamental Mystery of the Mind


Annaka Harris - 2019
    But the very existence of consciousness raises profound questions: Why would any collection of matter in the universe be conscious? How are we able to think about this? And why should we?In this wonderfully accessible book, Annaka Harris guides us through the evolving definitions, philosophies, and scientific findings that probe our limited understanding of consciousness. Where does it reside, and what gives rise to it? Could it be an illusion, or a universal property of all matter? As we try to understand consciousness, we must grapple with how to define it and, in the age of artificial intelligence, who or what might possess it. Conscious offers lively and challenging arguments that alter our ideas about consciousness—allowing us to think freely about it for ourselves, if indeed we can.

The Sports Gene: Inside the Science of Extraordinary Athletic Performance


David Epstein - 2013
    In college, I ran against Kenyans, and wondered whether endurance genes might have traveled with them from East Africa. At the same time, I began to notice that a training group on my team could consist of five men who run next to one another, stride for stride, day after day, and nonetheless turn out five entirely different runners. How could this be?We all knew a star athlete in high school. The one who made it look so easy. He was the starting quarterback and shortstop; she was the all-state point guard and high-jumper. Naturals. Or were they?The debate is as old as physical competition. Are stars like Usain Bolt, Michael Phelps, and Serena Williams genetic freaks put on Earth to dominate their respective sports? Or are they simply normal people who overcame their biological limits through sheer force of will and obsessive training?The truth is far messier than a simple dichotomy between nature and nurture. In the decade since the sequencing of the human genome, researchers have slowly begun to uncover how the relationship between biological endowments and a competitor’s training environment affects athleticism. Sports scientists have gradually entered the era of modern genetic research.In this controversial and engaging exploration of athletic success, Sports Illustrated senior writer David Epstein tackles the great nature vs. nurture debate and traces how far science has come in solving this great riddle. He investigates the so-called 10,000-hour rule to uncover whether rigorous and consistent practice from a young age is the only route to athletic excellence.Along the way, Epstein dispels many of our perceptions about why top athletes excel. He shows why some skills that we assume are innate, like the bullet-fast reactions of a baseball or cricket batter, are not, and why other characteristics that we assume are entirely voluntary, like an athlete’s will to train, might in fact have important genetic components.This subject necessarily involves digging deep into sensitive topics like race and gender. Epstein explores controversial questions such as:Are black athletes genetically predetermined to dominate both sprinting and distance running, and are their abilities influenced by Africa’s geography?Are there genetic reasons to separate male and female athletes in competition?Should we test the genes of young children to determine if they are destined for stardom?Can genetic testing determine who is at risk of injury, brain damage, or even death on the field?Through on-the-ground reporting from below the equator and above the Arctic Circle, revealing conversations with leading scientists and Olympic champions, and interviews with athletes who have rare genetic mutations or physical traits, Epstein forces us to rethink the very nature of athleticism.

Loneliness: Human Nature and the Need for Social Connection


John T. Cacioppo - 2008
    Cacioppo’s groundbreaking research topples one of the pillars of modern medicine and psychology: the focus on the individual as the unit of inquiry. By employing brain scans, monitoring blood pressure, and analyzing immune function, he demonstrates the overpowering influence of social context—a factor so strong that it can alter DNA replication. He defines an unrecognized syndrome—chronic loneliness—brings it out of the shadow of its cousin depression, and shows how this subjective sense of social isolation uniquely disrupts our perceptions, behavior, and physiology, becoming a trap that not only reinforces isolation but can also lead to early death. He gives the lie to the Hobbesian view of human nature as a “war of all against all,” and he shows how social cooperation is, in fact, humanity’s defining characteristic. Most important, he shows how we can break the trap of isolation for our benefit both as individuals and as a society.

13 Things That Don't Make Sense: The Most Baffling Scientific Mysteries of Our Time


Michael Brooks - 2008
    The effects of homeopathy don’t go away under rigorous scientific conditions. The laws of nature aren’t what they used to be. Thirty years on, no one has an explanation for a seemingly intelligent signal received from outer space. The US Department of Energy is re-examining cold fusion because the experimental evidence seems too solid to ignore. The placebo effect is put to work in medicine while doctors can’t agree whether it even exists.In an age when science is supposed to be king, scientists are beset by experimental results they simply can’t explain. But, if the past is anything to go by, these anomalies contain the seeds of future revolutions. While taking readers on an entertaining tour d’horizon of the strangest of scientific findings – involving everything from our lack of free will to Martian methane that offers new evidence of life on the planet – Michael Brooks argues that the things we don’t understand are the key to what we are about to discover.This mind-boggling but entirely accessible survey of the outer limits of human knowledge is based on a short article by Michael Brooks for New Scientist magazine. It became the sixth most circulated story on the internet in 2005, and provoked widespread comment and compliments (Google “13 things that do not make sense” to see).Michael Brooks has now dug deeply into those mysteries, with extraordinary results.

The Perfect Predator: A Scientist's Race to Save Her Husband from a Deadly Superbug: A Memoir


Steffanie Strathdee - 2019
    What at first seemed like a case of food poisoning quickly turned critical, and by the time Tom had been transferred via emergency medevac to the world-class medical center at UC San Diego, where both he and Steffanie worked, blood work revealed why modern medicine was failing: Tom was fighting one of the most dangerous, antibiotic-resistant bacteria in the world.Frantic, Steffanie combed through research old and new and came across phage therapy: the idea that the right virus, aka "the perfect predator," can kill even the most lethal bacteria. Phage treatment had fallen out of favor almost 100 years ago, after antibiotic use went mainstream. Now, with time running out, Steffanie appealed to phage researchers all over the world for help. She found allies at the FDA, researchers from Texas A&M, and a clandestine Navy biomedical center -- and together they resurrected a forgotten cure.

The Disordered Mind: What Unusual Brains Tell Us about Ourselves


Eric R. Kandel - 2018
    Kandel investigates The Disordered Mind to uncover what brain disorders reveal about human nature. This challenging study will not only help transform medical care but also encourage a new humanism based in part on the biological confirmation of individuality.Eric R. Kandel, the winner of the Nobel Prize in Physiology or Medicine for his foundational research into memory storage in the brain, is one of the pioneers of modern brain science. His work has helped shape our understanding of how learning and memory work. Building from this scientific research, Kandel explores one of the most fundamental questions we face: How does our mind, our individual sense of self, arise from the physical matter of the brain? The brain’s 86 billion neurons communicate with one another through very precise connections. If those connections are disrupted, the brain processes that give rise to our mind can become disordered, resulting in diseases such as depression, schizophrenia, Parkinson’s, and autism.The Disordered Mind illustrates how breakthrough studies of these disruptions can deepen our understanding of thought, feeling, behavior, memory, and creativity, and perhaps in the future will lead to the development of a unified theory of mind.

Why We Swim


Bonnie Tsui - 2020
      We swim in freezing Arctic waters and piranha-infested rivers to test our limits. We swim for pleasure, for exercise, for healing. But humans, unlike other animals that are drawn to water, are not natural-born swimmers. We must be taught. Our evolutionary ancestors learned for survival; now, in the twenty-first century, swimming is one of the most popular activities in the world.Why We Swim is propelled by stories of Olympic champions, a Baghdad swim club that meets in Saddam Hussein’s palace pool, modern-day Japanese samurai swimmers, and even an Icelandic fisherman who improbably survives a wintry six-hour swim after a shipwreck. New York Times contributor Bonnie Tsui, a swimmer herself, dives into the deep, from the San Francisco Bay to the South China Sea, investigating what about water—despite its dangers—seduces us and why we come back to it again and again.

A Taste for Poison: Eleven Deadly Molecules and the Killers Who Used Them


Neil Bradbury - 2022
    It can be slipped into a drink, smeared onto the tip of an arrow or the handle of a door, even filtered through the air we breathe. But how exactly do these poisons work to break our bodies down, and what can we learn from the damage they inflict?In a blend of popular science, medical history, and true crime, Dr. Neil Bradbury explores the morbidly captivating method of murder from a cellular level. Alongside real-life accounts of murderers and their crimes—some notorious, some forgotten, some still unsolved—are the stories of the poisons involved: eleven molecules of death that work their way through the human body and, paradoxically, illuminate the way in which our bodies function.Drawn from historical records and current news headlines, A Taste for Poison weaves together the tales of spurned lovers, shady scientists, medical professionals and political assassins to show how the precise systems of the body can be impaired to lethal effect through the use of poison. From the deadly origins of the gin & tonic cocktail to the arsenic-laced wallpaper in Napoleon’s bedroom.

When Death Becomes Life: Notes from a Transplant Surgeon


Joshua D. Mezrich - 2019
    Joshua Mezrich creates life from loss, transplanting organs from one body to another. In this intimate, profoundly moving work, he illuminates the extraordinary field of transplantation that enables this kind of miracle to happen every day.When Death Becomes Life is a thrilling look at how science advances on a grand scale to improve human lives. Mezrich examines more than one hundred years of remarkable medical breakthroughs, connecting this fascinating history with the inspiring and heartbreaking stories of his transplant patients. Combining gentle sensitivity with scientific clarity, Mezrich reflects on his calling as a doctor and introduces the modern pioneers who made transplantation a reality—maverick surgeons whose feats of imagination, bold vision, and daring risk taking generated techniques and practices that save millions of lives around the world.Mezrich takes us inside the operating room and unlocks the wondrous process of transplant surgery, a delicate, intense ballet requiring precise timing, breathtaking skill, and at times, creative improvisation. In illuminating this work, Mezrich touches the essence of existence and what it means to be alive. Most physicians fight death, but in transplantation, doctors take from death. Mezrich shares his gratitude and awe for the privilege of being part of this transformative exchange as the dead give their last breath of life to the living. After all, the donors are his patients, too.When Death Becomes Life also engages in fascinating ethical and philosophical debates: How much risk should a healthy person be allowed to take to save someone she loves? Should a patient suffering from alcoholism receive a healthy liver? What defines death, and what role did organ transplantation play in that definition? The human story behind the most exceptional medicine of our time, Mezrich’s riveting book is a beautiful, poignant reminder that a life lost can also offer the hope of a new beginning.

Endure: Mind, Body, and the Curiously Elastic Limits of Human Performance


Alex Hutchinson - 2018
    But over the past decade, a wave of dramatic findings in the cutting-edge science of endurance has completely overturned our understanding of human limitation. Endure widely disseminates these findings for the first time: It’s the brain that dictates how far we can go—which means we can always push ourselves further.Hutchinson presents an overview of science’s search for understanding human fatigue, from crude experiments with electricity and frogs’ legs to sophisticated brain imaging technology. Going beyond the traditional mechanical view of human limits (like a car with a brick on its gas pedal, we go until the tank runs out of gas), he instead argues that a key element in endurance is how the brain responds to distress signals—whether heat, or cold, or muscles screaming with lactic acid—and reveals that we can train to improve brain response.An elite distance runner himself, Hutchinson takes us to the forefront of the new sports psychology—brain electrode jolts, computer-based training, subliminal messaging—and presents startling new discoveries enhancing the performance of athletes today and shows how anyone can utilize these tactics to bolster their own performance—and get the most out of their bodies.

The Drug Hunters: The Improbable Quest to Discover New Medicines


Donald R. Kirsch - 2017
    Through serendipity— by chewing, brewing, and snorting—some Neolithic souls discovered opium, alcohol, snakeroot, juniper, frankincense, and other helpful substances. Ötzi the Iceman, the five-thousand-year-old hunter frozen in the Italian Alps, was found to have whipworms in his intestines and Bronze-age medicine, a worm-killing birch fungus, knotted to his leggings. Nowadays, Big Pharma conglomerates spend billions of dollars on state-of the art laboratories staffed by PhDs to discover blockbuster drugs. Yet, despite our best efforts to engineer cures, luck, trial-and-error, risk, and ingenuity are still fundamental to medical discovery.The Drug Hunters is a colorful, fact-filled narrative history of the search for new medicines from our Neolithic forebears to the professionals of today, and from quinine and aspirin to Viagra, Prozac, and Lipitor. The chapters offer a lively tour of how new drugs are actually found, the discovery strategies, the mistakes, and the rare successes. Dr. Donald R. Kirsch infuses the book with his own expertise and experiences from thirty-five years of drug hunting, whether searching for life-saving molecules in mudflats by Chesapeake Bay or as a chief science officer and research group leader at major pharmaceutical companies.