The author of The Lives of a Cell and The Medusa and the Snail now raises challenging questions about some of the major issues of our time—AIDS, drug abuse, and aging.With extraordinary perception, author Lewis Thomas discusses topics such as evolutionary biology, the development of language, the therapeutic aspects of medicine, and his love for his profession.

    Prusiner received a Nobel Prize, the world's most prestigious award for achievement in physiology or medicine. That he was the sole recipient of the award for the year was entirely appropriate, for his struggle to identify the agent responsible for ravaging the brains of animals suffering from scrapie and mad cow disease, and of humans with Creutzfeldt-Jakob disease, had been waged largely alone and in some cases in the face of strenuous disagreement.   In this book, Prusiner tells the remarkable story of his discovery of prions—infectious proteins that replicate and cause disease but surprisingly contain no genetic material—and reveals how superb and meticulous science is actually practiced using talented teams of researchers who persevere. He recounts the frustrations and rewards of years of research and offers fascinating portraits of his peers as they raced to discover the causes of fatal brain diseases. Prusiner’s hypothesis, once considered heresy, now stands as accepted science and the basis for developing diagnoses and eventual cures. He closes with a meditation on the legacy of his discovery: What will it take to cure Alzheimer’s, Parkinson’s, Lou Gehrig’s and other devastating diseases of the brain?

    Viruses are disarmingly small and simple. Nevertheless, the smallpox virus killed over 300 million people in the twentieth century before it was eradicated in 1980. The AIDSvirus, HIV, is now the world's biggest killer infection and the single most common cause of death in Africa. In recent years, the outbreaks of several lethal viruses such as Ebola and Hantavirus have caused great public concern--yet most people remain woefully ill-informed.In this fascinating new book, Dorothy Crawford explains lucidly and accessibly all aspects of the natural history of these deadly parasites and discusses controversial subjects such as CFS and Gulf War Syndrome. The book considers issues such as how man has coped with viruses in the past, where newviruses come from, and whether it would be possible for a new virus to wipe out the human race. Professor Crawford illustrates her arguments with vivid and wide-ranging examples. The result is an informative and highly readable book, which will be read by all those who seek a deeper understanding ofthese minute but remarkably efficient killers.

    Rich illustrations, systematic resumes, and extensive citations make it a valuable references source.

    Lisa Seachrist Chiu has a smorgasbord of stories to tell about rare and not so rare genetic quirks. We read about the Dracula Gene, a mutation in zebra fish that causes blood cells to explode on contact with light, and suites of genes that also influence behavior and physical characteristics; the Tangier Island Gene, first discovered after physicians discovered a boy with orange tonsils (scientists now realize that the child's odd condition comes from an inability to process cholesterol); and Wilson's Disease, a gene defect that fails to clear copper from the body, which can trigger schizophrenia and other neurological symptoms, and can be fatal if left untreated. Friendlier mutations include the Myostatin gene, which allows muscles to become much larger than usual and enhances strength and the much-envied Cheeseburger Gene, which allows a lucky few to eat virtually anything they want and remain razor thin. While fascinating us with stories of genetic peculiarities, Chiu also manages to effortlessly explain much of the cutting-edge research in modern genetics, resulting in a book that is both informative and entertaining. It is a must read for everyone who loves popular science or is curious about the human body.

    Spanning evolutionary science from its inception to its latest findings, from discoveries and data to philosophy and history, this book is an authoritative introduction to evolutionary biology.

    In Under the Knife, surgeon Arnold Van de Laar uses his own experience and expertise to tell the witty history of the past, present and future of surgery.From the story of the desperate man from seventeenth-century Amsterdam who grimly cut a stone out of his own bladder to Bob Marley's deadly toe, Under the Knife offers all kinds of fascinating and unforgettable insights into medicine and history via the operating theatre.What happens during an operation? How does the human body respond to being attacked by a knife, a bacterium, a cancer cell or a bullet? And, as medical advances continuously push the boundaries of what medicine can cure, what are the limits of surgery?From the dark centuries of bloodletting and of amputations without anaesthetic to today's sterile, high-tech operating theatres, Under the Knife is both a rich cultural history, and a modern anatomy class for us all.

    Things like why we yawn, why skin wrinkles after a bath, or even whether it's possible to keep a severed head alive: The Odd Body explains these and many other silly, weird, bizarre, and fascinating body mysteries. Dr. Stephen Juan entertains and rivets readers with his detailed answers.Reading The Odd Body is like having your doctor patiently answer all your random questions, one by one. But Dr. Juan goes well beyond the usual and ordinary things people wonder about bodies, like why most individuals are right-handed or why you get chills when chalk screeches across a blackboard. He also tells readers how a dead body is made into a mummy, the success rate of those who bore holes in their own heads to relieve headaches, and much, much more.The Odd Body is a unique combination of fun and fascinating material that's delivered by an expert who happens to be a great storyteller. The book's question-and-answer format makes it easy to pick up, turn to any page, and immediately become drawn into the intricacies of anatomy and physiology while gaining a better understanding of the human need to know more about ourselves.

    But aging does not have to mean decline. World-renowned surgeon Dr. Steven Gundry has been treating mature patients for most of his career. He knows that everyone thinks they want to live forever, until they hit middle age and witness the suffering of their parents and even their peers. So how do we solve the paradox of wanting to live to a ripe old age—but enjoy the benefits of youth?This groundbreaking book holds the answer. Working with thousands of patients, Dr. Gundry has discovered that the “diseases of aging” we most fear are not simply a function of age; rather, they are a byproduct of the way we have lived over the decades. In The Longevity Paradox, he maps out a new approach to aging well—one that is based on supporting the health of the “oldest” parts of us: the microorganisms that live within our bodies.Our gut bugs—the bacteria that make up the microbiome—largely determine our health over the years. From diseases like cancer and Alzheimer’s to common ailments like arthritis to our weight and the appearance of our skin, these bugs are in the driver’s seat, controlling our quality of life as we age.The good news is, it’s never too late to support these microbes and give them what they need to help them—and you—thrive. In The Longevity Paradox, Dr. Gundry outlines a nutrition and lifestyle plan to support gut health and live well for decades to come. A progressive take on the new science of aging, The Longevity Paradox offers an action plan to prevent and reverse disease as well as simple hacks to help anyone look and feel younger and more vital.

    Her twenty- five-year career conducting experiments that involve rats has led her to a surprising conclusion: Through their adaptive strategies and good habits, these unassuming little animals can teach us some essential lessons about how we, as humans, can lead successful lives. From emotional resilience and a strong work ethic to effective parenting and staying healthy, the lab rat is an unlikely but powerful role model for us all. This is a surprising and engaging guided tour into the sophisticated mental, emotional, and behavioral worlds of these frequently maligned and often misunderstood little creatures.

    The Human Genome Project finished sequencing human DNA. It seemed it was only a matter of time until we had all the answers to the secrets of life on this planet. The cutting-edge of biology, however, is telling us that we still don't even know all of the questions. How is it that, despite each cell in your body carrying exactly the same DNA, you don't have teeth growing out of your eyeballs or toenails on your liver? How is it that identical twins share exactly the same DNA and yet can exhibit dramatic differences in the way that they live and grow? It turns out that cells read the genetic code in DNA more like a script to be interpreted than a mould that replicates the same result each time. This is epigenetics and it's the fastest-moving field in biology today. The Epigenetics Revolution traces the thrilling path this discipline has taken over the last twenty years. Biologist Nessa Carey deftly explains such diverse phenomena as how queen bees and ants control their colonies, why tortoiseshell cats are always female, why some plants need a period of cold before they can flower, why we age, develop disease and become addicted to drugs, and much more. Most excitingly, Carey reveals the amazing possibilities for humankind that epigenetics offers for us all - and in the surprisingly near future.

    Too often, textbooks turn the fascinating systems, processes, and figures of anatomy into tedious discourse that even Leonardo Da Vinci would reject. This easy-to-read guide cuts out the boring details, and instead, provides you with a compelling lesson in anatomy. Covering every aspect of anatomical development and physiology, each chapter details the different parts of the human body, how systems are formed, and disorders that could disrupt bodily functions. You'll unravel the mysteries of anatomy with unique, accessible elements like: Detailed charts of each system in the body Illustrations of cross sections Unique profiles of the most influential figures in medical history From cell chemistry to the respiratory system, Anatomy 101 is packed with hundreds of entertaining facts that you can't get anywhere else!

    When Dr. Judy Mikovits finished her presentation the room was silent for a moment, then one of the scientists said, �Oh my God!” The resulting investigation would be like no other in science.For Dr. Mikovits, a twenty-year veteran of the National Cancer Institute, this was the midpoint of a five-year journey that would start with the founding of the Whittemore-Peterson Institute for Neuro-Immune Disease at the University of Nevada, Reno, and end with her as a witness for the federal government against her former employer, Harvey Whittemore, for illegal campaign contributions to Senate Majority Leader Harry Reid.On this journey Dr. Mikovits would face the scientific prejudices against CFS, wander into the minefield that is autism, and through it all struggle to maintain her faith in God and the profession to which she had dedicated her life. This is a story for anybody interested in the peril and promise of science at the very highest levels in our country.

    Barash, there are even more things that we don't know, genuine evolutionary mysteries that perplex the best minds in biology. Paradoxically, many of these mysteries are very close to home, involving some of the most personalaspects of being human.Homo Mysterious examines a number of these evolutionary mysteries, exploring things that we don't yet know about ourselves, laying out the best current hypotheses, and pointing toward insights that scientists are just beginning to glimpse. Why do women experience orgasm? Why do men have a shorterlifespan than women? Why does homosexuality exist? Why does religion exist in virtually every culture? Why do we have a fondness for the arts? Why do we have such large brains? And why does consciousness exist? Readers are plunged into an ocean of unknowns--the blank spots on the human evolutionarymap, the terra incognita of our own species--and are introduced to the major hypotheses that currently occupy scientists who are attempting to unravel each puzzle (including some solutions proposed here for the first time). Throughout the book, readers are invited to share the thrill of science atits cutting edge, a place where we know what we don't know, and, moreover, where we know enough to come up with some compelling and seductive explanations.Homo Mysterious is a guide to creative thought and future explorations, based on the best, most current thinking by evolutionary scientists. It captures the allure of the not-yet-known for those interested in stretching their scientific imaginations.