It's a modern Greek tragedy, as defined by Roger Dunkle in The Classical Origins of Western Culture: a story in which "the central character, called a tragic protagonist or hero, suffers some serious misfortune which is not accidental and therefore meaningless, but is significant in that the misfortune is logically connected."In other words? The bitch had it coming.

    The case would become one of the most famous in modern medicine—and a total failure. As Nature Made Him tells the extraordinary story of David Reimer, who, when finally informed of his medical history, made the decision to live as a male. A macabre tale of medical arrogance, it is first and foremost a human drama of one man's—and one family's—amazing survival in the face of terrible odds.

    She also lectures widely on autism—because Temple Grandin is autistic, a woman who thinks, feels, and experiences the world in ways that are incomprehensible to the rest of us. In this unprecedented book, Grandin delivers a report from the country of autism. Writing from the dual perspectives of a scientist and an autistic person, she tells us how that country is experienced by its inhabitants and how she managed to breach its boundaries to function in the outside world. What emerges in Thinking in Pictures is the document of an extraordinary human being, one who, in gracefully and lucidly bridging the gulf between her condition and our own, sheds light on the riddle of our common identity.

    Reflecting on the transitions in his life and in all our lives, he notices that “doorways are where the truth is told,” and wonders if there’s one thing–art, activism, family, money, fame–that could lead to a “life of meaning.” In a book that is candid, wise, and as questioning as it is incisive, Alda amuses and moves us with his uniquely hilarious meditations on questions great and small. Praise for Things I Overheard While Talking to Myself “Engagingly thoughtful and thought-provoking . . . [Alan Alda] candidly shares many stories of his life, so easily and wittily you can hear him speak as you read.”–Sydney Sun Herald“Alda is chatty, easygoing and humble, rather like a Mr. Rogers for grownups. His words of inspiration would be a perfect gift for a college grad or for anyone facing major life changes.”–Publishers Weekly (starred review)“Smart, engaged, funny and observant.”–San Antonio Express-News

    Fox stunned the world by announcing he had been diagnosed with Parkinson's disease -- a degenerative neurological condition. In fact, he had been secretly fighting it for seven years. The worldwide response was staggering. Fortunately, he had accepted the diagnosis, and by the time the public started grieving for him, he had stopped grieving for himself. Now, with the same passion, humor, and energy, that Fox has invested in his dozens of performances over the last 18 years, he tells the story of his life, his career, and his campaign, to find a cure for Parkinson's.Combining his trademark ironic sensibility, and keen sense of the absurd, he recounts his life -- from his childhood in a small town in western Canada, to his meteoric rise in film and television which made him a worldwide celebrity. Most importantly however, he writes of the last 10 years, during which -- with the unswerving support of his wife, family, and friends -- he has dealt with his illness. He talks about what Parkinson's has given him: the chance to appreciate a wonderful life and career, and the opportunity to help search for a cure, and spread public awareness of the disease. He is a very lucky man, indeed.

    Intrigued by its simple sign—Desforges Pianos—he enters, only to have his way barred by the shop's imperious owner.Unable to stifle his curiosity, he finally lands the proper introduction, and a world previously hidden is brought into view. Luc, the atelier's master, proves an indispensable guide to the history and art of the piano. Intertwined with the story of a musical friendship are reflections on how pianos work, their glorious history, and stories of the people who care for them, from amateur pianists to the craftsmen who make the mechanism sing. The Piano Shop on the Left Bank is at once a beguiling portrait of a Paris not found on any map and a tender account of the awakening of a lost childhood passion.

    Drawing inspiration from the shells on the shore, Lindbergh’s musings on the shape of a woman’s life bring new understanding to both men and women at any stage of life. A mother of five, an acclaimed writer and a pioneering aviator, Lindbergh casts an unsentimental eye on the trappings of modernity that threaten to overwhelm us: the time-saving gadgets that complicate rather than simplify, the multiple commitments that take us from our families. And by recording her thoughts during a brief escape from everyday demands, she helps readers find a space for contemplation and creativity within their own lives.With great wisdom and insight Lindbergh describes the shifting shapes of relationships and marriage, presenting a vision of life as it is lived in an enduring and evolving partnership. A groundbreaking, best-selling work when it was originally published in 1955, Gift from the Sea continues to be discovered by new generations of readers. With a new introduction by Lindbergh’s daughter Reeve, this fiftieth-anniversary edition will give those who are revisiting the book and those who are coming upon it for the first time fresh insight into the life of this remarkable woman.The sea and the beach are elements that have been woven throughout Anne Morrow Lindbergh’s life. She spent her childhood summers with her family on a Maine island. After her marriage to Charles Lindbergh in 1929, she accompanied him on his survey flights around the North Atlantic to launch the first transoceanic airlines. The Lindberghs eventually established a permanent home on the Connecticut coast, where they lived quietly, wrote books and raised their family.After the children left home for lives of their own, the Lindberghs traveled extensively to Africa and the Pacific for environmental research.

    Complications lays bare a science not in its idealized form but as it actually is--uncertain, perplexing, and profoundly human.Complications is a 2002 National Book Award Finalist for Nonfiction.

    A vivid, honest, and emotionally wrenching memoir, Wasted is the story of one woman's travels to reality's darker side—and her decision to find her way back on her own terms.

    A lanky kid from Plano, Texas, is raised by a feisty, single parent who sacrifices for her son, who becomes one of our country's greatest athletes. Given that background, it is understandable why Armstrong was able to channel his boundless energy toward athletic endeavors. By his senior year in high school, he was already a professional triathlete and was training with the U.S. Olympic cycling developmental team. In 1993, Armstrong secured a position in the ranks of world-class cyclists by winning the World Championship and a Tour de France stage, but in 1996, he was diagnosed with testicular cancer. Armstrong entered an unknown battlefield and challenged it as if climbing through the Alps: aggressive yet tactical. He beat the cancer and proceeded to stun all the pundits by winning the 1999 Tour de France. In this memoir, Armstrong covers his early years swiftly with a blunt matter-of-factness, but the main focus is on his battle with cancer. Readers will respond to the inspirational recovery story, and they will appreciate the behind-the-scenes cycling information. After he won the Tour, his mother was quoted as saying that her son's whole life has been a fight against the odds; we see here that she was not exaggerating. Brenda Barrera

    But there comes a point in her preteen years - maybe it's the night she first tries to run away and is exposed to drugs, alcohol, and sex all at once - when Cupcake's story shifts from a tear-jerking tragedy to a dark, deeply disturbing journey through hell.Cupcake learned to survive by turning tricks, downing hard liquor and ingesting every drug she could find while hitchhiking up and down the California coast. At just 16 she stumbled into the terrifying world of the gangsta, dealing drugs, hustling and only just surviving a drive-by shooting. Ironically, it was Cupcake's rapid descent into the nightmare of crack cocaine addiction that finally saved her. After one four-day crack binge she woke up behind a dumpster. Half-dressed and half-dead, she finally realized she had to change her life or die on the streets - another trash-can addict, another sad statistic.Astonishingly, Cupcake turned her life around and this is her brutally frank, startlingly funny story. Unlike any memoir you will ever read, A Piece of Cake is a redemptive, gripping tale of a resilient spirit who took on the worst of contemporary urban life and survived it. It is also the most genuinely affecting rollercoaster ride through hell and back that you will ever take.

    Sexually and physically abused by her father, Eve has struggled her whole life from this betrayal, longing for an honest reckoning from a man who is long dead. After years of work as an anti-violence activist, she decided she would wait no longer; an apology could be imagined, by her, for her, to her. The Apology, written by Eve from her father's point of view in the words she longed to hear, attempts to transform the abuse she suffered with unflinching truthfulness and compassion and an expansive vision for the future. Remarkable and original, The Apology is an acutely transformational look at how, from the wounds of sexual abuse, we can begin to re-emerge and heal. It is revolutionary, asking everything of each of us: courage, honesty, and forgiveness.

    At nine he started working on an original theory in astrophysics that experts believe may someday put him in line for a Nobel Prize, and at age twelve he became a paid researcher in quantum physics. But the story of Kristine’s journey with Jake is all the more remarkable because his extraordinary mind was almost lost to autism. At age two, when Jake was diagnosed, Kristine was told he might never be able to tie his own shoes. The Spark is a remarkable memoir of mother and son. Surrounded by “experts” at home and in special ed who tried to focus on Jake’s most basic skills and curtail his distracting interests—moving shadows on the wall, stars, plaid patterns on sofa fabric—Jake made no progress, withdrew more and more into his own world, and eventually stopped talking completely. Kristine knew in her heart that she had to make a change. Against the advice of her husband, Michael, and the developmental specialists, Kristine followed her instincts, pulled Jake out of special ed, and began preparing him for mainstream kindergarten on her own. Relying on the insights she developed at the daycare center she runs out of the garage in her home, Kristine resolved to follow Jacob’s “spark”—his passionate interests. Why concentrate on what he couldn’t do? Why not focus on what he could? This basic philosophy, along with her belief in the power of ordinary childhood experiences (softball, picnics, s’mores around the campfire) and the importance of play, helped Kristine overcome huge odds. The Barnetts were not wealthy people, and in addition to financial hardship, Kristine herself faced serious health issues. But through hard work and determination on behalf of Jake and his two younger brothers, as well as an undying faith in their community, friends, and family, Kristine and Michael prevailed. The results were beyond anything anyone could have imagined. Dramatic, inspiring, and transformative, The Spark is about the power of love and courage in the face of overwhelming obstacles, and the dazzling possibilities that can occur when we learn how to tap the true potential that lies within every child, and in all of us.

    Gifted Hands will transplace you into the operating room to witness surgeries that made headlines around the world, and into the private mind of a compassionate, God-fearing physician who lives to help others. In 1987, Dr. Carson gained worldwide recognition for his part in the first successful separation of Siamese twins joined at the back of the head -- an extremely complex and delicate operation that was five months of planning and twenty-two hours of actual surgery, involving a surgical plan that Carson helped initiate. Gifted Hands reveals a man with humility, decency, compassion, courage, and sensitivity who serves as a role model for young people (and everyone else) in need of encouragement to attempt the seemingly impossible and to excel in whatever they attempt. Dr. Carson also describes the key role that his highly intelligent though relatively uneducated mother played in his metamorphosis from an unmotivated ghetto youngster into one of the most respected neurosurgeons in the world.

    It was no wonder he gravitated to machines, which could, at least, be counted on.After fleeing his parents and dropping out of high school, his savant-like ability to visualize electronic circuits landed him a gig with KISS, for whom he created their legendary fire-breathing guitars. Later, he drifted into a “real” job, as an engineer for a major toy company. But the higher Robison rose in the company, the more he had to pretend to be “normal” and do what he simply couldn’t: communicate. It wasn’t worth the paycheck.It was not until he was forty that an insightful therapist told him he had the form of autism called Asperger’s syndrome. That understanding transformed the way Robison saw himself—and the world.Look Me in the Eye is the moving, darkly funny story of growing up with Asperger’s at a time when the diagnosis simply didn’t exist. A born storyteller, Robison takes you inside the head of a boy whom teachers and other adults regarded as “defective,” who could not avail himself of KISS’s endless supply of groupies, and who still has a peculiar aversion to using people’s given names (he calls his wife “Unit Two”). He also provides a fascinating reverse angle on the younger brother he left at the mercy of their nutty parents—the boy who would later change his name to Augusten Burroughs and write the bestselling memoir Running with Scissors.Ultimately, this is the story of Robison’s journey from his world into ours, and his new life as a husband, father, and successful small business owner—repairing his beloved high-end automobiles. It’s a strange, sly, indelible account—sometimes alien, yet always deeply human.