Kandel investigates The Disordered Mind to uncover what brain disorders reveal about human nature. This challenging study will not only help transform medical care but also encourage a new humanism based in part on the biological confirmation of individuality.Eric R. Kandel, the winner of the Nobel Prize in Physiology or Medicine for his foundational research into memory storage in the brain, is one of the pioneers of modern brain science. His work has helped shape our understanding of how learning and memory work. Building from this scientific research, Kandel explores one of the most fundamental questions we face: How does our mind, our individual sense of self, arise from the physical matter of the brain? The brain’s 86 billion neurons communicate with one another through very precise connections. If those connections are disrupted, the brain processes that give rise to our mind can become disordered, resulting in diseases such as depression, schizophrenia, Parkinson’s, and autism.The Disordered Mind illustrates how breakthrough studies of these disruptions can deepen our understanding of thought, feeling, behavior, memory, and creativity, and perhaps in the future will lead to the development of a unified theory of mind.

    While all other major diseases are in decline, deaths from Alzheimer’s have increased radically. What you or your loved ones don’t yet know is that 90 percent of Alzheimer’s cases can be prevented.Based on the largest clinical and observational study to date, neurologists and codirectors of the Brain Health and Alzheimer’s Prevention Program at Loma Linda University Medical Center, Drs. Dean and Ayesha Sherzai, offer in The Alzheimer’s Solution the first comprehensive program for preventing Alzheimer’s disease and improving cognitive function. Alzheimer’s disease isn’t a genetic inevitability, and a diagnosis does not need to come with a death sentence. Ninety percent of grandparents, parents, husbands, and wives can be spared. Ninety percent of us can avoid ever getting Alzheimer’s, and for the 10 percent with strong genetic risk for cognitive decline, the disease can be delayed by ten to fifteen years. This isn’t an estimate or wishful thinking; it’s a percentage based on rigorous science and the remarkable results the Sherzais have seen firsthand in their clinic.This much-needed revolutionary book reveals how the brain is a living universe, directly influenced by nutrition, exercise, stress, sleep, and engagement. In other words: what you feed it, how you treat it, when you challenge it, and the ways in which you allow it to rest. These factors are the pillars of the groundbreaking program you’ll find in these pages, which features a personalized assessment for evaluating risk, a five-part program for prevention and symptom-reversal, and day-by-day guides for optimizing cognitive function. You can prevent Alzheimer’s disease from affecting you, your family, friends, and loved ones. Even with a diagnosis, you can reverse cognitive decline and add vibrant years to your life. The future of your brain is finally within your control.

    No money. No passport. No identity.Taken to a mental hospital by the police, MacLean then started to hallucinate so severely he had to be tied down. Soon he could remember song lyrics, but not his family, his friends, or the woman he was told he loved. All of these symptoms, it turned out, were the result of the commonly prescribed malarial medication he had been taking. Upon his return to the States, he struggled to piece together the fragments of his former life in a harrowing, absurd, and unforgettable journey back to himself.The Answer to the Riddle Is Me, drawn from David MacLean’s award-winning This American Life essay, is a deeply felt, closely researched, and intensely personal book. It asks every reader to confront the essential questions of our age: In our geographically and chemically fluid world, what makes me who I am? And how much can be stripped away before I become someone else entirely?

    Anxiety. Chronic Pain. Phobias. Obsessive thoughts. The evidence is compelling: the roots of these difficulties may not reside in our immediate life experience or in chemical imbalances in our brains—but in the lives of our parents, grandparents, and even great-grandparents. The latest scientific research, now making headlines, supports what many have long intuited—that traumatic experience can be passed down through generations. It Didn’t Start with You builds on the work of leading experts in post-traumatic stress, including Mount Sinai School of Medicine neuroscientist Rachel Yehuda and psychiatrist Bessel van der Kolk, author of The Body Keeps the Score. Even if the person who suffered the original trauma has died, or the story has been forgotten or silenced, memory and feelings can live on. These emotional legacies are often hidden, encoded in everything from gene expression to everyday language, and they play a far greater role in our emotional and physical health than has ever before been understood.   As a pioneer in the field of inherited family trauma, Mark Wolynn has worked with individuals and groups on a therapeutic level for over twenty years. It Didn’t Start with You offers a pragmatic and prescriptive guide to his method, the Core Language Approach. Diagnostic self-inventories provide a way to uncover the fears and anxieties conveyed through everyday words, behaviors, and physical symptoms. Techniques for developing a genogram or extended family tree create a map of experiences going back through the generations. And visualization, active imagination, and direct dialogue create pathways to reconnection, integration, and reclaiming life and health. It Didn’t Start With You is a transformative approach to resolving longstanding difficulties that in many cases, traditional therapy, drugs, or other interventions have not had the capacity to touch.

    Six years later she made her first suicide attempt, then wandered the streets of New York City dressed in ragged clothes, tormenting voices crying out in her mind. Lori Schiller had entered the horrifying world of full-blown schizophrenia. She began an ordeal of hospitalizations, halfway houses, relapses, more suicide attempts, and constant, withering despair. But against all odds, she survived. Now in this personal account, she tells how she did it, taking us not only into her own shattered world, but drawing on the words of the doctors who treated her and family members who suffered with her.In this new edition, Lori Schiller recounts the dramatic years following the original publication -- a period involving addiction, relapse, and ultimately, love and recovery.Moving, harrowing, and ultimately uplifting, THE QUIET ROOM is a classic testimony to the ravages of mental illness and the power of perseverance and courage.

    The epidemics of obesity, heart disease, and diabetes are not tied to the overabundance of fat or carbs or any other specific nutrient. Instead, we have been led astray by the growing divide between flavor - the tastes we crave - and the underlying nutrition. Since the late 1940s, we have been slowly leeching flavor out of the food we grow. Those perfectly round, red tomatoes that grace our supermarket aisles today are mostly water, and the big breasted chickens on our dinner plates grow three times faster than they used to, leaving them dry and tasteless. Simultaneously, we have taken great leaps forward in technology, allowing us to produce in the lab the very flavors that are being lost on the farm. Thanks to this largely invisible epidemic, seemingly healthy food is becoming more like junk food: highly craveable but nutritionally empty. We have unknowingly interfered with an ancient chemical language - flavor - that evolved to guide our nutrition, not destroy it.With in-depth historical and scientific research, The Dorito Effect casts the food crisis in a fascinating new light, weaving an enthralling tale of how we got to this point and where we are headed. We've been telling ourselves that our addiction to flavor is the problem, but it is actually the solution. We are on the cusp of a new revolution in agriculture that will allow us to eat healthier and live longer by enjoying flavor the way nature intended.

    In pursuit of these things, it is undeterred by emotion, fear, or morality. Dopamine is the source of our every urge, that little bit of biology that makes an ambitious business professional sacrifice everything in pursuit of success, or that drives a satisfied spouse to risk it all for the thrill of someone new. Simply put, it is why we seek and succeed; it is why we discover and prosper. Yet, at the same time, it’s why we gamble and squander. From dopamine’s point of view, it’s not the having that matters. It’s getting something—anything—that’s new. From this understanding—the difference between possessing something versus anticipating it—we can understand in a revolutionary new way why we behave as we do in love, business, addiction, politics, religion – and we can even predict those behaviors in ourselves and others. In The Molecule of More: How a Single Chemical in Your Brain Drives Love, Sex, and Creativity—and will Determine the Fate of the Human Race, George Washington University professor and psychiatrist Daniel Z. Lieberman, MD, and Georgetown University lecturer Michael E. Long present a potentially life-changing proposal: Much of human life has an unconsidered component that explains an array of behaviors previously thought to be unrelated, including why winners cheat, why geniuses often suffer with mental illness, why nearly all diets fail, and why the brains of liberals and conservatives really are different.

    Barbara Ravage has fashioned an enlightening, invaluable book.” —Stewart O’Nan, author of The Circus Fire: A True Story of an American TragedyThough each of us is just a spark away from being a burn victim, the public knows little and understands less about the world that patients inhabit. Pulling the curtains back on this private and sterile environment, Burn Unit is a riveting account of the frontline efforts—both modern-day and historical—to save lives devastated by fire. With unflinching urgency, Barbara Ravage follows an extraordinary team of healers at Massachusetts General Hospital, the cradle of modern burn treatment and the site of one of the best burn units in the world. From Boston’s Cocoanut Grove fire of 1942 to the treatment of the victims of the Rhode Island nightclub fire in early 2003, we watch everyday heroes do their incredible but punishing work against the backdrop of history. Both a moving human drama and an engrossing scientific exploration of this little-known field of medicine, Burn Unit is an unforgettably powerful read.

    The surprising thing is just how counterintuitive some of these strategies can be. Feeling the urge to procrastinate? Do nothing for 20 minutes and you'll feel ready to get to work. Want to strengthen your athletic performance? The imagination and mental "practice" can be just as beneficial as putting on your sweats and heading to the gym. Come down with a case of the blues? Try eating some fermented foods such as yogurt or sourdough bread. Outsmart Yourself: Brain-Based Strategies to a Better You will give you insights into how your mind works and the tools you need to make lasting change. Taught by Professor Peter M. Vishton, Associate Professor of Psychology at William & Mary, these 24 exciting lectures give you a wealth of practical strategies to strengthen your creativity, improve your problem-solving, enhance your health, and generally improve your well-being. Whether we're distracted by too many tasks, being influenced by crafty marketers, or simply living in a rut of bad habits, our conscious brains aren't always guiding us toward the best actions. Fortunately, Professor Vishton offers the latest in scientific research to outsmart the subconscious.

    Within days of their first meeting in 2003, they were planning a life together, and soon they were inseparable as Michael became ever more integrated into Marilu’s family. But after only months they were thrown the ultimate curveball: Michael was diagnosed with bladder cancer, and then lung cancer. Marilu refused to lose the love of her life so easily. With the knowledge she had gained on her own health journey, chronicled in several of her bestselling books, Marilu set about finding a path for Michael that would use the best of Eastern and Western medicine to beat his cancers and return Michael to optimal health. Michael eschewed most traditional treatments and with Marilu’s help—aided by knowledgeable and sympathetic doctors—he forged his own path. In this moving and informative book, Marilu tells the story of their fast-paced romance and how this contrasted with the day-to-day battle for Michael’s life. Michael tells the story from his point of view: the search for the cause of his cancer, the mental anguish he felt as he realized how responsible he was for his condition, the physical and mental hardships that he had to overcome, and the triumph of love that made it all worthwhile. Not a “how-to” book in the traditional sense, Changing Normal is a book of empowerment, a call for all those facing similar challenges to take responsibility for their lives, to search for the causes of their illness and address them directly. Written with an engaging voice, a sense of humor, and life-changing wisdom, Changing Normal is a personal and touching look at how Marilu and Michael faced down a cancer diagnosis and came out the other side happier, healthier, and more in love than ever.

    His contribution to our understanding not only of mental illness but also of the human condition is truly stunning.The Noonday Demon examines depression in personal, cultural, and scientific terms. Drawing on his own struggles with the illness and interviews with fellow sufferers, doctors and scientists, policymakers and politicians, drug designers and philosophers, Solomon reveals the subtle complexities and sheer agony of the disease. He confronts the challenge of defining the illness and describes the vast range of available medications, the efficacy of alternative treatments, and the impact the malady has had on various demographic populations around the world and throughout history. He also explores the thorny patch of moral and ethical questions posed by emerging biological explanations for mental illness.The depth of human experience Solomon chronicles, the range of his intelligence, and his boundless curiosity and compassion will change the reader's view of the world.

    Through the eyes of a curious scientist, she watched her mind deteriorate whereby she could not walk, talk, read, write, or recall any of her life. Because of her understanding of the brain, her respect for the cells in her body, and an amazing mother, Jill completely recovered. In My Stroke of Insight, she shares her recommendations for recovery and the insight she gained into the unique functions of the two halves of her brain. When she lost the skills of her left brain, her consciousness shifted away from normal reality where she felt "at one with the universe." Taylor helps others not only rebuild their brains from trauma, but helps those of us with normal brains better understand how we can consciously influence the neural circuitry underlying what we think, how we feel and how we react to life's circumstances.

    That judgment, implausible even to a casual fan, also contradicted the opinion of a growing cadre of neuroscientists who worked in vain to convince the NFL that it was facing a deadly new scourge: A chronic brain disease that was driving an alarming number of players -- including some of the all-time greats -- to madness.League of Denial reveals how the NFL, over a period of nearly two decades, sought to cover up and deny mounting evidence of the connection between football and brain damage.Comprehensively, and for the first time, award-winning ESPN investigative reporters Mark Fainaru-Wada and Steve Fainaru tell the story of a public health crisis that emerged from the playing fields of our 21st century pastime. Everyone knew that football is violent and dangerous. But what the players who built the NFL into a $10 billion industry didn’t know – and what the league sought to shield from them – is that no amount of padding could protect the human brain from the force generated by modern football; that the very essence of the game could be exposing these players to brain damage.In a fast-paced narrative that moves between the NFL trenches, America’s research labs and the boardrooms where the NFL went to war against science, League of Denial examines how the league used its power and resources to attack independent scientists and elevate its own flawed research -- a campaign with echoes of Big Tobacco’s fight to deny the connection between smoking and lung cancer. It chronicles the tragic fates of players like Hall of Fame Pittsburgh Steelers center Mike Webster, who was so disturbed at the time of his death he fantasized about shooting NFL executives; and former Chargers great Junior Seau, whose diseased brain became the target of an unseemly scientific battle between researchers and the NFL. Based on exclusive interviews, previously undisclosed documents and private emails, this is the story of what the NFL knew and when it knew it – questions at the heart of crisis that threatens football, from the highest levels all the way down to Pop Warner.

    In only a few decades, the medical system has been overrun by organizations seeking to exploit for profit the trust that vulnerable and sick Americans place in their healthcare. Our politicians have proven themselves either unwilling or incapable of reining in the increasingly outrageous costs faced by patients, and market-based solutions only seem to funnel larger and larger sums of our money into the hands of corporations. Impossibly high insurance premiums and inexplicably large bills have become facts of life; fatalism has set in. Very quickly Americans have been made to accept paying more for less. How did things get so bad so fast?Breaking down this monolithic business into the individual industries--the hospitals, doctors, insurance companies, and drug manufacturers--that together constitute our healthcare system, Rosenthal exposes the recent evolution of American medicine as never before. How did healthcare, the caring endeavor, become healthcare, the highly profitable industry? Hospital systems, which are managed by business executives, behave like predatory lenders, hounding patients and seizing their homes. Research charities are in bed with big pharmaceutical companies, which surreptitiously profit from the donations made by working people. Patients receive bills in code, from entrepreneurial doctors they never even saw.The system is in tatters, but we can fight back. Dr. Elisabeth Rosenthal doesn't just explain the symptoms, she diagnoses and treats the disease itself. In clear and practical terms, she spells out exactly how to decode medical doublespeak, avoid the pitfalls of the pharmaceuticals racket, and get the care you and your family deserve. She takes you inside the doctor-patient relationship and to hospital C-suites, explaining step-by-step the workings of a system badly lacking transparency. This is about what we can do, as individual patients, both to navigate the maze that is American healthcare and also to demand far-reaching reform. An American Sickness is the frontline defense against a healthcare system that no longer has our well-being at heart.

    (The somewhat confusing title is from a line in Zorba the Greek in which the title character refers to the ups and downs of family life as "the full catastrophe.") But this book is also a terrific introduction for anyone who has considered meditating but was afraid it would be too difficult or would include religious practices they found foreign. Kabat-Zinn focuses on "mindfulness," a concept that involves living in the moment, paying attention, and simply "being" rather than "doing." While you can practice anything "mindfully," from taking a walk to cleaning your house, Kabat-Zinn presents several meditation techniques that focus the attention most clearly, whether it's on a simple phrase, your breathing, or various parts of your body. The book goes into detail about how hospital patients have either improved their health or simply come to feel better despite their illness by using these techniques, but these meditations can help anyone deal with stress and gain a calmer outlook on life. "When we use the word healing to describe the experiences of people in the stress clinic, what we mean above all is that they are undergoing a profound transformation of view," Kabat-Zinn writes. "Out of this shift in perspective comes an ability to act with greater balance and inner security in the world." --Ben Kallenreissue 2005