But in the inevitable condition of aging and death, the goals of medicine seem too frequently to run counter to the interest of the human spirit. Nursing homes, preoccupied with safety, pin patients into railed beds and wheelchairs. Hospitals isolate the dying, checking for vital signs long after the goals of cure have become moot. Doctors, committed to extending life, continue to carry out devastating procedures that in the end extend suffering.Gawande, a practicing surgeon, addresses his profession's ultimate limitation, arguing that quality of life is the desired goal for patients and families. Gawande offers examples of freer, more socially fulfilling models for assisting the infirm and dependent elderly, and he explores the varieties of hospice care to demonstrate that a person's last weeks or months may be rich and dignified.

    Instead of succumbing to the new age wave of sliding onto an app, she goes old school - placing a personal ad in her hometown newspaper, hoping to spark a love connection. Bringing an additional lady into his life wasn't in Theodore “Rux” Reed‘s life plan, but you know what they say about the best laid plans... When the perfect woman is literally dropped at his doorstep, he was powerless to resist the desire to get to know her. With less than one literal degree of separation between them, Kai and Rux’s paths collide and unfurl into a journey of evolution & self-realization.

    This is the memoir of Joan, who started nursing in the 1940s and whose experiences took her into the Yorkshire mining pits and through the tumult of the 1984-85 miners’ strike.Joan Hart always knew what she wanted to do with her life. Born in South Yorkshire in 1932, she started her nursing training when she was 16, the youngest age girls could do so at the time. She continued working after she married and her work took her to London and Doncaster, caring for children and miners.When she took a job as a pit nurse in Doncaster in 1974, she found that in order to be accepted by the men under her care, she would have to become one of them. Most of the time rejecting a traditional nurse’s uniform and donning a baggy miner’s suit, pit boots, a hardhat and a headlamp, Joan resolved always to go down to injured miners and bring them out of the pit herself.Over 15 years Joan grew to know the miners not only as a nurse, but as a confidante and friend. She tended to injured miners underground, rescued men trapped in the pits, and provided support for them and their families during the bitter miners’ strike which stretched from March 1984 to 1985.Moving and uplifting, this is a story of one woman’s life, marriage and work; it is guaranteed to make readers laugh, cry, and smile.

    Prior to the tournament, a statistician calculated the Bulldogs as a 200-to-1 shot to win. But as fascinating as what Butler accomplished was how they did it. Underdawgs tells the incredible and uplifting story. Butler’s coach, 33-year-old Brad Stevens, looked so young he was often mistaken for one of the players, but he had quickly become one of the best coaches in the nation by employing the “Butler Way.” This philosophy of basketball and life, adopted by former coach Barry Collier, is based on five principles: humility, passion, unity, servanthood, and thankfulness. Even the most casual observer could see this in every player, on the court and off, from NBA first-round draft pick Gordon Hayward to the last guy on the bench. Butler was coming off a great 2009–10 regular season, but its longtime existence on the periphery of major college basketball fostered doubt as March Madness set in. But after two historic upsets, one of top-seeded Syracuse and another of second-seeded Kansas State, and making it to the Final Four, the Bulldogs came within the diameter of a shoelace of beating the perennial leaders of college basketball: the Duke Blue Devils. Much more than a sports story, Underdawgs is the consummate David versus Goliath tale. Despite Duke’s winning the championship, the Bulldogs proved they belonged in the game and, in the process, won the respect of people who were not even sports fans.

    Whatever the ideological fad of the moment, American populism has always been home to a fascinating assortment of charismatic leaders, characters, kooks, cranks, and sometimes charlatans who have - with widely varying degrees of success - led the charge of ordinary folks who have gotten wise to the ways of the swamp. This attitude of skeptical resentment also makes populism a fertile field for the work of conspiracy theorists and other enthusiastic apostates from civic convention. After all, if the people in power are found to be rigging one part of the system, why not the rest? Every Man a King tells the stories of America's populist leaders, from an elderly Andrew Jackson brutally caning his would-be-assassin, to William Jennings Bryan's pre-speech routine that combined equally prodigious quantities of prayer and food, to Ross Perot's military-style campaign that made even volunteers wear badges with stars to show rank. It is a rollicking history of an American attitude that has shaped not only our current moment, but also the long struggle over who gets to define the truths we hold to be self evident.

    Barbara Ravage has fashioned an enlightening, invaluable book.” —Stewart O’Nan, author of The Circus Fire: A True Story of an American TragedyThough each of us is just a spark away from being a burn victim, the public knows little and understands less about the world that patients inhabit. Pulling the curtains back on this private and sterile environment, Burn Unit is a riveting account of the frontline efforts—both modern-day and historical—to save lives devastated by fire. With unflinching urgency, Barbara Ravage follows an extraordinary team of healers at Massachusetts General Hospital, the cradle of modern burn treatment and the site of one of the best burn units in the world. From Boston’s Cocoanut Grove fire of 1942 to the treatment of the victims of the Rhode Island nightclub fire in early 2003, we watch everyday heroes do their incredible but punishing work against the backdrop of history. Both a moving human drama and an engrossing scientific exploration of this little-known field of medicine, Burn Unit is an unforgettably powerful read.

    Thousands of fans flocked to multi‑day events, and cities vied with one another to host them. The pilots themselves were hailed as dashing heroes who cheerfully stared death in the face. Well, the men were hailed. Female pilots were more often ridiculed than praised for what the press portrayed as silly efforts to horn in on a manly, and deadly, pursuit. Fly Girls recounts how a cadre of women banded together to break the original glass ceiling: the entrenched prejudice that conspired to keep them out of the sky. O’Brien weaves together the stories of five remarkable women: Florence Klingensmith, a high‑school dropout who worked for a dry cleaner in Fargo, North Dakota; Ruth Elder, an Alabama divorcee; Amelia Earhart, the most famous, but not necessarily the most skilled; Ruth Nichols, who chafed at the constraints of her blue‑blood family’s expectations; and Louise Thaden, the mother of two young kids who got her start selling coal in Wichita. Together, they fought for the chance to race against the men — and in 1936 one of them would triumph in the toughest race of all.   Like Hidden Figures and Girls of Atomic City, Fly Girls celebrates a little-known slice of history in which tenacious, trail-blazing women braved all obstacles to achieve greatness.

    Using video links, IP Factly's Amazing Animal series has been designed to encourage and bolster independent reading. The animals are accompanied by pictures and facts plus video links so children can see the animals and how they behave.

    He Jiankui announced that he had created the first genetically modified babies—twin girls named Lulu and Nana—sending shockwaves around the world. A year later, a Chinese court sentenced Dr. He to three years in prison for "illegal medical practice."As scientists elsewhere start to catch up with China’s vast genetic research program, gene editing is fueling an innovation economy that threatens to widen racial and economic inequality. Fundamental questions about science, health, and social justice are at stake: Who gets access to gene editing technologies? As countries loosen regulations around the globe, from the U.S. to Indonesia, can we shape research agendas to promote an ethical and fair society?Eben Kirksey takes us on a groundbreaking journey to meet the key scientists, lobbyists, and entrepreneurs who are bringing cutting-edge genetic engineering tools like CRISPR to your local clinic. He also ventures beyond the scientific echo chamber, talking to disabled scholars, doctors, hackers, chronically-ill patients, and activists who have alternative visions of a genetically modified future for humanity.The Mutant Project empowers us to ask the right questions, uncover the truth, and navigate this brave new world.

    Combining linguistics and cultural history, Gaston Dorren takes us on an intriguing tour of the continent, from Proto-Indo-European (the common ancestor of most European languages) to the rise and rise of English, via the complexities of Welsh plurals and Czech pronunciation. Along the way we learn why Esperanto will never catch on, how the language of William the Conqueror lives on in the Channel Islands and why Finnish is the easiest European language.Surprising, witty and full of extraordinary facts, this book will change the way you think about the languages around you. Polyglot Gaston Dorren might even persuade you that English is like Chinese.

    

    The popularity of murder mystery books, TV series, and even board games shows that there is an appetite for death, and the more unusual or macabre the method, the better. With gunshots or stabbings the cause of death is obvious, but poisons are inherently more mysterious. How are some compounds so deadly in such tiny amounts?Agatha Christie used poison to kill her characters more often than any other crime fiction writer. The poison was a central part of the novel, and her choice of deadly substances was far from random; the chemical and physiological characteristics of each poison provide vital clues to the discovery of the murderer. Christie demonstrated her extensive chemical knowledge (much of it gleaned by working in a pharmacy during both world wars) in many of her novels, but this is rarely appreciated by the reader.Written by former research chemist Kathryn Harkup, each chapter takes a different novel and investigates the poison used by the murderer. Fact- and fun-packed, A is for Arsenic looks at why certain chemicals kill, how they interact with the body, and the feasibility of obtaining, administering, and detecting these poisons, both when Christie was writing and today.

    Pretending to work? That’s fudgelling, which may lead to rizzling if you feel sleepy after lunch, though by dinner time you will have become a sparkling deipnosophist.From Mark Forsyth, author of the bestselling The Etymologicon, this is a book of weird words for familiar situations. From ante-jentacular to snudge by way of quafftide and wamblecropt, at last you can say, with utter accuracy, exactly what you mean.

    By allowing women to control their fertility, the birth control pill has revolutionized women's lives. Women are going to college, graduating, and entering the workforce in greater numbers than ever before, and there's good reason to believe that the birth control pill has a lot to do with this. But there's a lot more to the pill than meets the eye.Although women go on the pill for a small handful of targeted effects (pregnancy prevention and clearer skin, yay!), sex hormones can't work that way. Sex hormones impact the activities of billions of cells in the body at once, many of which are in the brain. There, they play a role in influencing attraction, sexual motivation, stress, hunger, eating patterns, emotion regulation, friendships, aggression, mood, learning, and more. This means that being on the birth control pill makes women a different version of themselves than when they are off of it. And this is a big deal. For instance, women on the pill have a dampened cortisol spike in response to stress. While this might sound great (no stress!), it can have negative implications for learning, memory, and mood. Additionally, because the pill influences who women are attracted to, being on the pill may inadvertently influence who women choose as partners, which can have important implications for their relationships once they go off it. Sometimes these changes are for the better . . . but other times, they're for the worse. By changing what women's brains do, the pill also has the ability to have cascading effects on everything and everyone that a woman encounters. This means that the reach of the pill extends far beyond women's own bodies, having a major impact on society and the world.This paradigm-shattering book provides an even-handed, science-based understanding of who women are, both on and off the pill. It will change the way that women think about their hormones and how they view themselves. It also serves as a rallying cry for women to demand more information from science about how their bodies and brains work and to advocate for better research. This book will help women make more informed decisions about their health, whether they're on the pill or off of it.

    This man was a freediver, and his amphibious abilities inspired Nestor to seek out the secrets of this little-known discipline. In Deep, Nestor embeds with a gang of extreme athletes and renegade researchers who are transforming not only our knowledge of the planet and its creatures, but also our understanding of the human body and mind. Along the way, he takes us from the surface to the Atlantic’s greatest depths, some 28,000 feet below sea level. He finds whales that communicate with other whales hundreds of miles away, sharks that swim in unerringly straight lines through pitch-black waters, and seals who dive to depths below 2,400 feet for up to eighty minutes—deeper and longer than scientists ever thought possible. As strange as these phenomena are, they are reflections of our own species’ remarkable, and often hidden, potential—including echolocation, directional sense, and the profound physiological changes we undergo when underwater. Most illuminating of all, Nestor unlocks his own freediving skills as he communes with the pioneers who are expanding our definition of what is possible in the natural world, and in ourselves.