With the assistance of a co-author, this popular student textbook has now been updated to include techniques such as membrane chromatography, aqueous phase partitioning, engineering recombinant proteins for purification and due to the rapid advances in bioinformatics/proteomics a discussion of the analysis of complex protein mixtures by 2D-electrophoresis and RPHPLC prior to sequencing by mass spectroscopy. Written with the student firmly in mind, no previous knowledge of biochemistry, and little of chemistry, is assumed. It is intended to provide an introduction to enzymology, and a balanced account of all the various theoretical and applied aspects of the subject which are likely to be included in a course.

    The objective here is to explain science in a simple, attractive and fun form that is open to all.The first axiom of this approach was set out as follows: “We believe in the magic of science. We hope to show you that sci-ence is not a secret art, accessible only to a dedicated few. It involves learning about nature and society, and aspects of our existence which affect us all, and which we should all therefore have the chance to understand. We shall interpret science for those who might not speak its language fluently, but want to understand its meaning. We don’t teach, we just tell stories about the beginnings of science, the natural phenomena and the underlying principles through which they occur, and the lives of the people who discovered them.”The aim of the writings collected in this series is to present some key scientific events, ideas and personalities in the form of short stories that are easy and fun to read. Scientific and philo-sophical concepts are explained in a way that anyone may under-stand. Each story may be read separately, but at the same time they all band together to form a wide-ranging introduction to the history of science and areas of contemporary scientific research, as well as some of the recurring problems science has encountered in history and the philosophical dilemmas it raises today.Review“If I were the only survivor on a remote island and all I had with me were this book, a Swiss army knife and a bottle, I would throw the bottle into the sea with the note: ‘Don’t worry, I have everything I need.’”— Ciril Horjak, alias Dr. Horowitz, a comic artist“The writing is understandable, but never simplistic. Instructive, but never patronizing. Straightforward, but never trivial. In-depth, but never too intense.”— Ali Žerdin, editor at Delo, the main Slovenian newspaper“Does science think? Heidegger once answered this question with a decisive No. The writings on modern science skillfully penned by Sašo Dolenc, these small stories about big stories, quickly convince us that the contrary is true. Not only does science think in hundreds of unexpected ways, its intellectual challenges and insights are an inexhaustible source of inspiration and entertainment. The clarity of thought and the lucidity of its style make this book accessible to anyone … in the finest tradition of popularizing science, its achievements, dilemmas and predicaments.”— Mladen Dolar, philosopher and author of A Voice and Nothing More“Sašo Dolenc is undoubtedly one of our most successful authors in the field of popular science, possessing the ability to explain complex scientific achievements to a broader audience in a clear and captivating way while remaining precise and scientific. His collection of articles is of particular importance because it encompasses all areas of modern science in an unassuming, almost light-hearted manner.”— Boštjan Žekš, physicist and former president of the Slovenian Academy of Sciences and Arts

    Includes tables to compare different agents within a given class of drugs. For use as a review for Boards, self-testing, or reference. Previous edition: c1997.

      In the constellation of Eridanus, there lurks a cosmic mystery: It’s as if something has taken a huge bite out of the universe. But what is the culprit? The hole in the universe is just one of many puzzles keeping cosmologists busy. Supermassive black holes, bubbles of nothingness gobbling up space, monster universes swallowing others—these and many other bizarre ideas are being pursued by scientists. Due to breathtaking progress in astronomy, the history of our universe is now better understood than the history of our own planet. But these advances have uncovered some startling riddles. In this electrifying new book, renowned cosmologist and author Paul Davies lucidly explains what we know about the cosmos and its enigmas, exploring the tantalizing—and sometimes terrifying—possibilities that lie before us. As Davies guides us through the audacious research offering mind-bending solutions to these and other mysteries, he leads us up to the greatest outstanding conundrum of all: Why does the universe even exist in the first place? And how did a system of mindless, purposeless particles manage to bring forth conscious, thinking beings? Filled with wit and wonder, What’s Eating the Universe? is a dazzling tour of cosmic questions, sure to entertain, enchant, and inspire us all.

    Using illustrations and examples from science fiction pulp magazines and comic books, The Amazing Story of Quantum Mechanics explains the fundamental principles of quantum mechanics that underlie the world we live in.Watch a Video

    In this delightful and compelling exploration of our most neglected sense, veteran science reporter Bob Holmes shows us just how much we’re missing.Considering every angle of flavor from our neurobiology to the science and practice of modern food production, Holmes takes readers on a journey to uncover the broad range of factors that can affect our appreciation of a fine meal or an exceptional glass of wine. He peers over the shoulders of some of the most fascinating food professionals working today, from cutting-edge chefs to food engineers to mathematicians investigating the perfect combination of pizza toppings. He talks with flavor and olfactory scientists, who describe why two people can experience remarkably different sensations from the same morsel of food, and how something as seemingly unrelated as cultural heritage can actually impact our sense of smell.Along the way, even more surprising facts are revealed: that cake tastes sweetest on white plates; that wine experts’ eyes can fool their noses; and even that language can affect our sense of taste. Flavor expands our curiosity and understanding of one of our most intimate sensations, while ultimately revealing how we can all sharpen our senses and our enjoyment of the things we taste.Certain to fascinate everyone from gourmands and scientists to home cooks and their guests, Flavor will open your mind—and palette—to a vast, exciting sensory world.

    It features a biography of the author, a full-length analysis of the novel, and a great deal more. If you're studying this novel, reading it for your book club, or if you simply want to know more about it, you'll find this guide informative and helpful. Part of a new series of guides to contemporary novels. The aim of the series is to give readers accessible and informative introductions to some of the most popular, most acclaimed and most influential novels of recent years - from ‘The Remains of the Day' to ‘White Teeth'. A team of contemporary fiction scholars from both sides of the Atlantic has been assembled to provide a thorough and readable analysis of each of the novels in question.

    Cosmic Universe and Human History, microcosm and macrocosm, inorganic and living matter coexist and form a unique unity manifested in multiple forms. The Physical and the Mental constitute the form and the content of the World. The world does not consist of subjects and objects, the “subject” and the “object” are metaphysical abstractions of the single and indivisible Wholeness. Man’s finite knowledge separates the Whole into parts and studies fragmentarily the beings. The Wholeness is manifested in multiple forms and each form encapsulates the Wholeness. The rational explanation of the excerpts and the intuitive apprehension of the Wholeness are required to combine and create the open thought and the holistic knowledge. This means that the measurement should be defined by the ''measure'', but the responsibility for determining the ''measure'' depends on the man. This requires that man overcomes the anthropocentric arrogance and the narcissistic selfishness and he joins the Cosmic World in a friendly and creative manner.

    Whatever your circumstances, you can create the life you desire by following simple, counterintuitive steps; not the steps society wants you to follow. Unfortunately, you cannot even trust yourself when it comes to creating the life that you desire, because you’re programmed by your past, an accumulation of hundreds of thousands of years, a mind still adapted for a hunter-gatherer time period. What does this mean? It means every day you’re battling your emotions, logic versus emotion. Logically, you want to do one thing, but emotionally, you are drawn to something else. First, if this sounds familiar, then great, because it means you are human. But, if you’re going to win the game of life, you cannot sit around and wait for things to happen, because you’ll be living a life of supreme comfort and sameness; ultimately, a great sin. You are destined for great things, capable of forging dreams and living your aspirations. Maybe you’ve forgotten about this truth: that you are capable, worthy, and ready. Maybe you’ve been beaten into the ground by life, a teacher who doesn’t care if you’re rich or poor, weak or strong, ready or not, because life will continue forward regardless, waiting for no one. Fortunately, there’re things you can do to set yourself apart from the millions that will ultimately suffer and fail. One such thing, perhaps the most powerful of all, is by studying the great, people who have succeeded and who have gone beyond what is humanly thought possible. When it comes to studying someone great, there’s one name that stands tall, Stephen Hawking, a person who has persevered and flourished. Not only has he conquered great adversity, but he has inspired millions around the world with his brilliant mind. There is a reason why people compare him with the once living Albert Einstein, the genius. What follows are Stephen Hawking’s greatest life lessons, gems of wisdom that you can easily apply to your own life, which will help you live a more abundant, stronger life. If you’re in need of inspiration, a boost of confidence, or just a friendly reminder of the wonders in life, you’ve come to the right place. See for yourself why millions study his work and regard him as a genius. Scroll up and grab your copy today.*** Limited time offer ***

    After days of treatment for recurring infection, it becomes obvious that her arm must be amputated. Dr. Ajay Seth, the son of immigrant parents from India and a local orthopaedic surgeon in private practice, performs his first-ever amputation procedure. In the months that follow, divine intervention, combined with Melissa’s determination and Dr. Seth’s disciplined commitment and dedication to his patients, brings about the opportunity for a medical breakthrough that will potentially transform the lives of amputees around the world.Rewired is the inspirational, miraculous story of Dr. Seth’s revolutionary surgery that allows Melissa to not just move a prosthetic arm simply by thinking, but to actually feel with the prosthetic hand, just as she would with her natural arm. This resulted in what others have recognized as the world’s most advanced amputee, all done from Dr. Seth’s private practice in a community hospital, using a local staff, and with no special training or extensive research funding.

    Experienced birders use the most easily observed characteristics — size, structure, behavior, and general color patterns — to identify birds even before looking carefully at plumage details. Now birders at all levels can learn how to identify shorebirds quickly and simply. This guide includes more than 870 stunning color photographs, starting with a general impression of the species and progressing to more detailed images of the bird throughout its life cycle. Quiz questions in the captions will engage and challenge all birders and help them benefit from this simplified, commonsense approach to identification.

    Written in a concise, bulleted outline format, this well-illustrated text offers 500 USMLE-style review questions, answers, and explanations and features comprehensive content and upgraded USMLE Step 1 information.

    This is type of problems asked at the JEE (IIT). The purpose of this book is to show students how to handle such problems and give them sufficient practice in solving problems of this type, thus building their confidence. The main features of this book are:Each chapter begins with a summary of facts, formulate and working techniques. Trick, tips and techniques have been clearly marked with the icon.A large number of problems have been solved and explained in each chapter.The exercises contain short-answer, long-answer and objective type questions.Multiple-choice questions in which more than one option may be correct have also been given.Time-bound tests at the end of each chapter will help students practise answering questions in a given time.The book also includes integrated tests, bases on all the chapters.A chapter containing miscellaneous problems has been given at the end of the book. This will help students gain confidence in solving problems without prior knowledge of the chapter(s) to which the problems belong.Table of ContentsAlgebraProgressions, Related Inequalities and SeriesDeterminants and Cramer's RuleEquations, Inequations and ExpressionsComplex NumbersPermutation and CombinationBinomial Theorem for Positive Integral IndexPrinciple of Mathematical Induction (PMI)Infinite SeriesMatricesTrigonometryCircular Functions, IdentitiesSolution of EquationsInverse Circular FunctionsTrigonometrical Inequalities and InequationsLogarithmProperties of TriangleHeights and DistancesCoordinate GeometryCoordinates and Straight LinesPairs of Straight Lines and Transformation of AxesCirclesParabolaEllipse and HyperbolaCalculusFunctionDifferentiationLimit, Indeterminate FormContinuity, Differentiability and Graph of FunctionApplication of dy/dxMaxima and MinimaMonotonic Function and Lagrange's TheoremIndefinite In

    Laughlin transports us two centuries into the future, when we've ceased to use carbon from the ground--either because humans have banned carbon burning or because fuel has simply run out. Boldly, Laughlin predicts no earth-shattering transformations will have taken place. Six generations from now, there will still be soccer moms, shopping malls, and business trips. Firesides will still be snug and warm.How will we do it? Not by discovering a magic bullet to slay our energy problems, but through a slew of fascinating technologies, drawing on wind, water, and fire. Powering the Future is an objective yet optimistic tour through alternative fuel sources, set in a world where we've burned every last drop of petroleum and every last shovelful of coal.The Predictable: Fossil fuels will run out. The present flow of crude oil out of the ground equals in one day the average flow of the Mississippi River past New Orleans in thirteen minutes. If you add the energy equivalents of gas and coal, it's thirty-six minutes. At the present rate of consumption, we'll be out of fossil fuels in two centuries' time. We always choose the cheapest gas. From the nineteenth-century consolidation of the oil business to the California energy crisis of 2000-2001, the energy business has shown, time and again, how low prices dominate market share. Market forces--not green technology--will be the driver of energy innovation in the next 200 years. The laws of physics remain fixed. Energy will still be conserved, degrade entropically with use, and have to be disposed of as waste heat into outer space. How much energy a fuel can pack away in a given space is fixed by quantum mechanics--and if we want to keep flying jet planes, we will need carbon-based fuels. The Potential: Animal waste. If dried and burned, the world's agricultural manure would supply about one-third as much energy as all the coal we presently consume. Trash. The United States disposes of 88 million tons of carbon in its trash per year. While the incineration of waste trash is not enough to contribute meaningfully to the global demand for energy, it will constrain fuel prices by providing a cheap supply of carbon. Solar energy. The power used to light all the cities around the world is only one-millionth of the total power of sunlight pouring down on earth's daytime side. And the amount of hydropump storage required to store the world's daily electrical surge is equal to only eight times the volume of Lake Mead. PRAISE FOR ROBERT B. LAUGHLIN -Perhaps the most brilliant theoretical physicist since Richard Feynman---George Chapline, Lawrence Livermore National Laboratory -Powerful but controversial.--- Financial Times -[Laughlin's] company ... is inspirational.- --New Scientist

    You’re unlikely to forget the experiences or regret the sharing.