Viruses are disarmingly small and simple. Nevertheless, the smallpox virus killed over 300 million people in the twentieth century before it was eradicated in 1980. The AIDSvirus, HIV, is now the world's biggest killer infection and the single most common cause of death in Africa. In recent years, the outbreaks of several lethal viruses such as Ebola and Hantavirus have caused great public concern--yet most people remain woefully ill-informed.In this fascinating new book, Dorothy Crawford explains lucidly and accessibly all aspects of the natural history of these deadly parasites and discusses controversial subjects such as CFS and Gulf War Syndrome. The book considers issues such as how man has coped with viruses in the past, where newviruses come from, and whether it would be possible for a new virus to wipe out the human race. Professor Crawford illustrates her arguments with vivid and wide-ranging examples. The result is an informative and highly readable book, which will be read by all those who seek a deeper understanding ofthese minute but remarkably efficient killers.

    Written especially for exercise science and physical education students, this text provides a solid foundation in theory illuminated by application and performance models to increase understanding and to help students apply what they've learned in the classroom and beyond.

    From weight lifting for men and women in the early days, to jogging in the 1970s, cycling in the 1980s, aerobics in the 1990s, and now Spinning, Kolata explains the science of conditioning and the objective evidence behind commonly accepted prescriptions. Ultimate Fitness is also a book about the individuals who have challenged and influenced or failed to influence the industry, and the many of us who have participated in this multimillion-dollar corner of American culture.

    Most people say they would like to die quietly at home. But overly aggressive medical advice, coupled with an unrealistic sense of invincibility or overconfidence in our health-care system, results in the majority of elderly patients misguidedly dying in institutions. Many undergo painful procedures instead of having the better and more peaceful death they deserve.At Peace outlines specific active and passive steps that older patients and their health-care proxies can take to ensure loved ones live their last days comfortably at home and/or in hospice when further aggressive care is inappropriate. Through Dr. Samuel Harrington's own experience with the aging and deaths of his parents and of working with patients, he describes the terminal patterns of the six most common chronic diseases; how to recognize a terminal diagnosis even when the doctor is not clear about it; how to have the hard conversation about end-of-life wishes; how to minimize painful treatments; when to seek hospice care; and how to deal with dementia and other special issues. Informed by more than thirty years of clinical practice, Dr. Harrington came to understand that the American health-care system wasn't designed to treat the aging population with care and compassion. His work as a hospice trustee and later as a hospital trustee drove his passion for helping patients make appropriate end-of-life decisions.

    Teresi introduces us to brain-death experts, hospice workers, undertakers, coma specialists and those who have recovered from coma, organ transplant surgeons and organ procurers, anesthesiologists who study pain in legally dead patients, doctors who have saved living patients from organ harvests, nurses who care for beating-heart cadavers, ICU doctors who feel subtly pressured to declare patients dead rather than save them, and many others. Much of what they have to say is shocking. Teresi also provides a brief history of how death has been determined from the times of the ancient Egyptians and the Incas through the twenty-first century. And he draws on the writings and theories of celebrated scientists, doctors, and researchers—Jacques-Bénigne Winslow, Sherwin Nuland, Harvey Cushing, and Lynn Margulis, among others—to reveal how theories about dying and death have changed. With The Undead, Teresi makes us think twice about how the medical community decides when someone is dead.

    microbe.” —The Wall Street Journal   Did the Black Death destroy medieval Europe? Did cholera pave the way for modern Manhattan? Did yellow fever help end the slave trade? Remarkably, the answer to all of these questions is yes. Time and again, diseases have impacted the course of human history in surprisingly powerful ways. From influenza to smallpox, from tuberculosis to yellow fever, Bryn Barnard describes the symptoms and paths of the world’s worst diseases—and how the epidemics they spawned have changed history forever.   Filled with fascinating, often gory details about disease and history, Outbreak! is a wonderful combination of science and history.

    That means most people alive today will spend more years in elderhood than in childhood, and many will be elders for 40 years or more. Yet at the very moment that humans are living longer than ever before, we've made old age into a disease, a condition to be dreaded, denigrated, neglected, and denied. Reminiscent of Oliver Sacks, noted Harvard-trained geriatrician Louise Aronson uses stories from her quarter century of caring for patients, and draws from history, science, literature, popular culture, and her own life to weave a vision of old age that's neither nightmare nor utopian fantasy--a vision full of joy, wonder, frustration, outrage, and hope about aging, medicine, and humanity itself. Elderhood is for anyone who is, in the author's own words, "an aging, i.e., still-breathing human being."

    For decades, these questions have lived exclusively in the realm of science fiction, but as Kevin Davies powerfully reveals in his new book, this is all about to change.Engrossing and page-turning, Editing Humanity takes readers inside the fascinating world of a new gene editing technology called CRISPR, a high-powered genetic toolkit that enables scientists to not only engineer but to edit the DNA of any organism down to the individual building blocks of the genetic code.Davies introduces readers to arguably the most profound scientific breakthrough of our time. He tracks the scientists on the front lines of its research to the patients whose powerful stories bring the narrative movingly to human scale.Though the birth of the “CRISPR babies” in China made international news, there is much more to the story of CRISPR than headlines seemingly ripped from science fiction. In Editing Humanity, Davies sheds light on the implications that this new technology can have on our everyday lives and in the lives of generations to come.

    Today, says Dale Purves, the dominant research agenda may have taken us as far as it can--and neuroscientists may be approaching a paradigm shift. In this highly personal book, Purves reveals how we got to this point and offers his notion of where neuroscience may be headed next. Purves guides you through a half-century of the most influential ideas in neuroscience and introduces the extraordinary scientists and physicians who created and tested them. Purves offers a critical assessment of the paths that neuroscience research has taken, their successes and their limitations, and then introduces an alternative approach for thinking about brains. Building on new research on visual perception, he shows why common ideas about brain networks can't be right and uncovers the factors that determine our subjective experience. The resulting insights offer a deeper understanding of what it means to be human. - Why we need a better conception of what brains are trying to do and how they do it Approaches to understanding the brain over the past several decades may be at an impasse - The surprising lessons that can be learned from what we see How complex neural processes owe more to trial-and-error experience than to logical principles - Brains--and the people who think about them Meet some of the extraordinary individuals who've shaped neuroscience - The -ghost in the machine- problem The ideas presented further undermine the concept of free will

    Richard Louis Miller discusses what is happening today in psychedelic medicine--and what will happen in the future--with top researchers and thinkers in this field, including Rick Doblin, Stanislav Grof, James Fadiman, Julie Holland, Dennis McKenna, David Nichols, Charles Grob, Phil Wolfson, Michael and Annie Mithoefer, Roland Griffiths, Katherine MacLean, and Robert Whitaker. Dr. Miller and his contributors cover the tumultuous history of early psychedelic research brought to a halt 50 years ago by the U.S. government as well as offering non-technical summaries of the most recent studies with MDMA, psilocybin, LSD, and ayahuasca. They explore the biochemistry of consciousness and the use of psychedelics for self-discovery and healing. They discuss the use of psilocybin for releasing fear in the terminally ill and the potential for MDMA-assisted psychotherapy in the treatment of PTSD. They examine Dr. Charles Grob’s research on the indigenous use and therapeutic properties of ayahuasca and Dr. Gabor Mate’s attempt to transport this plant medicine to a clinical setting with the help of Canada’s Department of National Health. Dr. Miller and his contributors explore the ongoing efforts to restore psychedelic therapies to the health field, the growing threat of overmedication by the pharmaceutical industry, and the links between psychiatric drugs and mental illness. They also discuss the newly shifting political climate and the push for new research, offering hope for an end to the War on Drugs and a potential renaissance of research into psychedelic medicines around the world.

    Some of these drugs are truly transformative, offering major improvements in how long patients live or how they feel--but what is often missing from the popular narrative is that, far too often, these new drugs have marginal or minimal benefits. Some are even harmful. In Malignant, hematologist-oncologist Dr. Vinayak K. Prasad writes about the many sobering examples of how patients are too often failed by cancer policy and by how oncology is practiced. Throughout this work, Prasad illuminates deceptive practices which- promote novel cancer therapies long before credible data are available to support such treatment; and- exaggerate the potential benefits of new therapies, many of which cost thousands and in some cases hundreds of thousands of dollars.Prasad then critiques the financial conflicts of interest that pervade the oncology field, the pharmaceutical industry, and the US Food and Drug administration.This is a book about how the actions of human beings--our policies, our standards of evidence, and our drug regulation--incentivize the pursuit of marginal or unproven therapies at lofty and unsustainable prices. Prasad takes us through how cancer trials are conducted, how drugs come to market, and how pricing decisions are made, asking how we can ensure that more cancer drugs deliver both greater benefit and a lower price. Ultimately, Prasad says,- more cancer clinical trials should measure outcomes that actually matter to people with cancer;- patients on those trials should look more like actual global citizens;- we need drug regulators to raise, not perpetually lower, the bar for approval; and- we need unbiased patient advocates and experts.This well-written, opinionated, and engaging book explains what we can do differently to make serious and sustained progress against cancer--and how we can avoid repeating the policy and practice mistakes of the past.

    That all changed in less than a generation with the discovery and development of a new category of medicine known as antibiotics. By 1955, the age-old evolutionary relationship between humans and microbes had been transformed, trivializing once-deadly infections. William Rosen captures this revolution with all its false starts, lucky surprises, and eccentric characters. He explains why, given the complex nature of bacteria—and their ability to rapidly evolve into new forms—the only way to locate and test potential antibiotic strains is by large-scale, systematic, trial-and-error experimentation. Organizing that research needs large, well-funded organizations and businesses, and so our entire scientific-industrial complex, built around the pharmaceutical company, was born. Timely, engrossing, and eye-opening, Miracle Cure is a must-read science narrative—a drama of enormous range, combining science, technology, politics, and economics to illuminate the reasons behind one of the most dramatic changes in humanity’s relationship with nature since the invention of agriculture ten thousand years ago.

    This is a summary and review of the original book. Available in a variety of formats, this summary offers you as a reader the opportunity to enjoy great writings.when you might not have the time to read the original book Being Mortal, by writer Atul Gawande focuses on several critical issues that include death, aging, mortality and critical and terminal illness. The writer has included vast research and has chronicled stories and experiences of his own patients, patients of other doctors and stories of his members of the family. The story based on these experiences provides information to readers regarding various circumstances, life situations and scenarios, which can facilitate people to find an optimum journey through the final days of their own lives or the lives of their family members. Key Takeaways 1. Nursing homes neither have been created for assisting elderly persons to reduce their level of dependency on another person nor to provide better options than the poorhouses. The purpose for creating nursing homes is clearing hospital beds. 2. Assisted living therefore has risen from the requirement to provide alternative solution to nursing homes, which can make patients more independent and have a better grip over their own lives. 3. Most people, in the later years of their own lives want something more than survival and that is where nursing homes, medical institutions and assisted living fail. 4. People must question what makes life worth living at the time when they get old, are frail, ill and have to depend on another person for their daily care.

    Your brain is a collection of maps. That is no metaphor: scrawled across your brain’s surfaces are actual maps of the sights, sounds, and actions that hold the key to your survival. Scientists first began uncovering these maps over a century ago, but we are only now beginning to unlock their secrets—and comprehend their profound impact on our lives. Brain maps distort and shape our experience of the world, support complex thought, and make technology-enabled mind reading a modern-day reality, which raises important questions about what is real, what is fair, and what is private. They shine a light on our past and our possible futures. In the process, they invite us to view ourselves from a startling new perspective.  ​ In Brainscapes, Rebecca Schwarzlose combines unforgettable real-life stories, cutting-edge research, and vivid illustrations to reveal brain maps’ surprising lessons about our place in the world—and about the world’s place within us.

    When an epidemic hits, the EIS will be there to crack the case, however mysterious or deadly, saving countless lives in the process. Over the years they have successfully battled polio, cholera, and smallpox, to name a few, and in recent years have turned to the epidemics killing us now--smoking, obesity, and gun violence among them.The successful EIS model has spread internationally: former EIS officers on the staff of the Centers for Disease Control have helped to establish nearly thirty similar programs around the world. EIS veterans have gone on to become leaders in the world of public health in organizations such as the World Health Organization."Inside the Outbreaks" takes readers on a riveting journey through the history of this remarkable organization, following Epidemic Intelligence Service officers on their globetrotting quest to eliminate the most lethal and widespread threats to the world's health.