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    New findings in molecular biology challenge the gene-centered version of Darwinian theory according to which adaptation occurs only through natural selection of chance DNA variations. In Evolution in Four Dimensions, Eva Jablonka and Marion Lamb argue that there is more to heredity than genes. They trace four dimensions in evolution -- four inheritance systems that play a role in evolution: genetic, epigenetic (or non-DNA cellular transmission of traits), behavioral, and symbolic (transmission through language and other forms of symbolic communication). These systems, they argue, can all provide variations on which natural selection can act. Evolution in Four Dimensions offers a richer, more complex view of evolution than the gene-based, one-dimensional view held by many today. The new synthesis advanced by Jablonka and Lamb makes clear that induced and acquired changes also play a role in evolution. After discussing each of the four inheritance systems in detail, Jablonka and Lamb put Humpty Dumpty together again by showing how all of these systems interact. They consider how each may have originated and guided evolutionary history and they discuss the social and philosophical implications of the four-dimensional view of evolution. Each chapter ends with a dialogue in which the authors engage the contrarieties of the fictional (and skeptical) I.M., or Ifcha Mistabra -- Aramaic for the opposite conjecture -- refining their arguments against I.M.'s vigorous counterarguments. The lucid and accessible text is accompanied by artist-physician Anna Zeligowski's lively drawings, which humorously and effectively illustrate the authors' points.

    The book was based on a course of public lectures delivered by Schrödinger in February 1943 at Trinity College, Dublin. Schrödinger's lecture focused on one important question: "how can the events in space and time which take place within the spatial boundary of a living organism be accounted for by physics and chemistry?" In the book, Schrödinger introduced the idea of an "aperiodic crystal" that contained genetic information in its configuration of covalent chemical bonds. In the 1950s, this idea stimulated enthusiasm for discovering the genetic molecule and would give both Francis Crick and James Watson initial inspiration in their research.

    The man behind the much-loved, larger-than-life personality; not only an astronomer but also a self-taught musician and talented composer, and passionate supporter of cricket.

    An x-ray microscope would do the trick, or since we're dreaming, perhaps an Asimov-style nanosubmarine (unfortunately, neither is currently feasible). Think of the wonders we could witness firsthand: antibodies atta- ing a virus, electrical signals racing down nerve fibers, proteins building new strands of DNA. Many of the questions puzzling the current cadre of sci- tists would be answered at a glance. But the nanoscale world of molecules is separated from our everyday world of experience by a daunting million-fold difference in size, so the world of molecules is completely invisible. I created the illustrations in this book to help bridge this gulf and allow us to see the molecular structure of cells, if not directly, then in an artistic rendition. I have included two types of illustrations with this goal in mind: watercolor paintings which magnify a small portion of a living cell by one million times, showing the arrangement of molecules inside, and comput- generated pictures, which show the atomic details of individual molecules. In this second edition of The Machinery of Life, these illustrations are presented in full color, and they incorporate many of the exciting scientific advances of the 15 years since the first edition.

    Not so anymore. All but exterminated, these predators of the not-too-distant past have been reduced to minor players of the modern era. And what of it? Wildlife journalist William Stolzenburg follows in the wake of nature's topmost carnivores, and finds chaos in their absence.From the brazen mobs of deer and marauding raccoons of backyard America to streamsides of Yellowstone National Park crushed by massive herds of elk; from urchin-scoured reefs in the North Pacific to ant-devoured islands in Venezuela, Stolzenburg leads a startling tour through bizarre, impoverished landscapes of pest and plague. For anyone who has seldom given thought to the meat-eating beasts so recently missing from the web of life, here is a world of reason to think again.

    He traces the trajectory of his life—from a childhood spent exploring the Gulf Coast of Alabama and Florida to life as a tenured professor at Harvard—detailing how his youthful fascination with nature blossomed into a lifelong calling. He recounts with drama and wit the adventures of his days as a student at the University of Alabama and his four decades at Harvard University, where he has achieved renown as both teacher and researcher.As the narrative of Wilson's life unfolds, the reader is treated to an inside look at the origin and development of ideas that guide today's biological research. Theories that are now widely accepted in the scientific world were once untested hypotheses emerging from one man's broad-gauged studies. Throughout Naturalist, we see Wilson's mind and energies constantly striving to help establish many of the central principles of the field of evolutionary biology. The story of Edward O. Wilson's life provides fascinating insights into the making of a scientist and a valuable look at some of the most thought-provoking ideas of our time.

    He is one of the foremost figures of contemporary neuroscience, and his decades-long quest to understand the inner workings of the brain’s memory machine has begun to pay off. Award-winning journalist Terry McDermott spent nearly two years observing Lynch at work and now gives us a fascinating and dramatic account of daily life in his lab—the highs and lows, the drudgery and eureka moments, the agonizing failures. He provides detailed, lucid explanations of the cutting-edge science that enabled Lynch to reveal the inner workings of the molecular machine that manufactures memory. After establishing the building blocks, Lynch then set his sights on uncovering the complicated structure of memory as it is stored across many neurons. Adding practical significance to his groundbreaking work, Lynch discovered a class of drugs that could fix the memory machine when it breaks, drugs that would enhance brain function during the memory process and that hold out the possibility of cures for a wide range of neurological conditions, including Alzheimer’s disease, Parkinson’s disease, and attention deficit hyperactivity disorder. Here is an essential story of science, scientists, and scientific achievement—galvanizing in the telling and thrilling in its far-reaching implications.

    C. J. Peters was on the front lines of our biological battle against “hot” viruses around the world. In the course of that career, he learned countless lessons about our interspecies turf wars with infectious agents. Called in to contain an outbreak of deadly hemorrhagic fever in Bolivia, he confronted the despair of trying to save a colleague who accidentally infected himself with an errant scalpel. Working in Level 4 labs on the Machupo and Ebola viruses, he saw time and again why expensive high-tech biohazard containment equipment is only as safe as the people who use it.   Because of new, emerging viruses, and the return of old, “vanquished” ones for which vaccines do not exist, there remains a very real danger of a new epidemic that could, without proper surveillance and early intervention, spread worldwide virtually overnight. And the possibility of foreign countries or terrorist groups using deadly airborne viruses—the poor man’s nuclear arsenal—looms larger than ever.   High-octane science writing at its best and most revealing, Virus Hunter is a thrilling first-person account of what it is like to be a warrior in the Hot Zone.

    James Cleaves II seek to answer the most crucial question in science: How did life begin? They trace the trials and triumphs of the iconoclastic scientists who have sought to solve the mystery, from Darwin’s theory of evolution to Crick and Watson’s unveiling of DNA. This fascinating exploration not only examines the origin-of-life question, but also interrogates the very nature of scientific discovery and objectivity.

    In an era when women were rarely permitted any serious schooling, this twenty-seven-year-old’s nimble conversation and unusual brilliance led Voltaire, then in his late thirties, to wonder, “Why did you only reach me so late?” They fell immediately and passionately in love.Through the prism of their tumultuous fifteen-year relationship we see the crumbling of an ancient social order and the birth of the Enlightenment. Together the two lovers rebuilt a dilapidated and isolated rural chateau at Cirey where they conducted scientific experiments, entertained many of the leading thinkers of the burgeoning scientific revolution, and developed radical ideas about the monarchy, the nature of free will, the subordination of women, and the separation of church and state. But their time together was filled with far more than reading and intellectual conversation. There were frantic gallopings across France, sword fights in front of besieged German fortresses, and a deadly burning of Voltaire’s books by the public executioner at the base of the grand stairwell of the Palais de Justice in Paris. The pair survived court intrigues at Versailles, narrow escapes from agents of the king, a covert mission to the idyllic lakeside retreat of Frederick the Great of Prussia, forays to the royal gambling tables (where Emilie put her mathematical acumen to lucrative use), and intense affairs that bent but did not break their bond.Along with its riveting portrait of Voltaire as a vulnerable romantic, Passionate Minds at last does justice to the supremely unconventional life and remarkable achievements of Emilie du Châtelet—including her work on the science of fire and the nature of light. Long overlooked, her story tells us much about women’s lives at the time of the Enlightenment. Equally important, it demonstrates how this graceful, quick-witted, and attractive woman worked out the concepts that would lead directly to the “squared” part of Einstein’s revolutionary equation: E=mc2.Based on a rich array of personal letters, as well as writings from houseguests, neighbors, scientists, and even police reports, Passionate Minds is both panoramic and intimate in feeling. It is an unforgettable love story and a vivid rendering of the birth of modern ideas.

    So how does chemistry give rise to biology? What could have led the first replicating molecules up such a path? Now, developments in the emerging field of 'systems chemistry' are unlocking the problem. Addy Pross shows how the different kind of stability that operates among replicating molecules results in a tendency for chemical systems to become more complex and acquire the properties of life. Strikingly, he demonstrates that Darwinian evolution is the biological expression of a deeper, well-defined chemical concept: the whole story from replicating molecules to complex life is one continuous process governed by an underlying physical principle. The gulf between biology and the physical sciences is finally becoming bridged.

    Essentials of Orthopaedics & Applied Physiotherapy

    Following a bidding war between Justin Timberlake and Usher, the fifteen-year-old singing sensation has had four singles hit the Top 40—before his first record was even released. With that kind of popularity, it’s no wonder that Harlee Harte, author of the “I ♥” series, is on the case! Harlee is the celebrity columnist for Hollywoodland High’s student newspaper. Accompanied by her fun, fashion-forward and fabulous friends, Harlee’s “all-access” press credentials let her get up close and personal with Justin backstage, on the road, and even at major awards ceremonies. Not just a paste-up of Justin Bieber facts, Harlee’s columns are full of puzzles, quizzes, and games that bring her devoted readers closer to this top tween celebrity than ever before. Follow Harlee on Justin’s trail as she tries to juggle the ups and downs, twists and turns of her everyday teenage life—school, boys, girlfriends, parents, and, of course, staying connected with all things Bieber.

    Coming eighteen years after the publication of The Ants, this new volume expands our knowledge of the social insects (among them, ants, bees, wasps, and termites) and is based on remarkable research conducted mostly within the last two decades. These superorganisms—a tightly knit colony of individuals, formed by altruistic cooperation, complex communication, and division of labor—represent one of the basic stages of biological organization, midway between the organism and the entire species. The study of the superorganism, as the authors demonstrate, has led to important advances in our understanding of how the transitions between such levels have occurred in evolution and how life as a whole has progressed from simple to complex forms. Ultimately, this book provides a deep look into a part of the living world hitherto glimpsed by only a very few.