Top magazines including Fortune and Industry Week have repeatedly named it one of America's best companies to work for.In Science Lessons, Gordon Binder—CEO and chairman during 1988-2000—describes Amgen's climb to success. Revealing the highs and lows it experienced in the race to develop blockbuster drugs, he takes readers from the time Amgen had just three months of capital in the bank and no viable products in the pipeline to its spectacular success. The turning point? The 1989 launch of Epogen, which dramatically helped kidney dialysis patients suffering from debilitating anemia. Other landmark drugs, including Neupogen, would follow.Through engaging anecdotes and cogent insights, Binder weaves a fascinating tale while offering his unique brand of practical management advice. Using the principals of the scientific method, he shares his recommendations for tackling pressing business challenges—such as managing creative employees, navigating the IPO process, and protecting intellectual property.This colorful first-person account showcases the visionary science and daring business strategy that made Amgen great—offering valuable lessons for all companies.

    Table of Contents General Information Vol I Diversity in the Living World Structural Organisation in Plants and Animals Cell Structure and Function Plant Physiology Human Physiology Vol II Reproduction Genetics and Evolution Biology and Human Welfare Biotechnology and Its Applications Ecology and Environment Some More Additional Topics Assertion and Research Questions top

    It includes extensive material on molecular biology, and presents biochemistry from a chemist's perspective.

    Now that future looms before us. Don’t panic! This book is all you need to prepare for the new world that awaits us, providing indispensable cautionary advice on topics such as • bioenhancements: They’re not just for cyborgs anymore. • DNA sequencing and fingerprinting: What’s scarier than the government having your DNA on file? Try having it posted on the Internet.• human cloning: Just like you, only stronger, smarter, and more attractive. In other words: more dangerous. Our future may be populated by designer babies, genetically enhanced supersoldiers, and one (or more!) of your genetic duplicates, but all is not lost. How to Defeat Your Own Clone is the ultimate survival guide to what lies ahead. Just remember the first rule of engagement: Don’t ever let your clone read this book!

    It explores comprehensive set of commands that will make it easy to build applications and get them up and running quickly. Making the move to C is easy and fast with this concise, on target book by noted C expert R.B. Patel. The book's extensive exercise and frequent language comparisons teach you C concepts quickly and introduces the power of C language based on Turbo-C standard. The book covers the latest language features including detailed discussions of Data Base Design & System S/W and installation S/W. This book is written for beginners as well as advanced programmers. ? Contents Introduction Data Type Loops and Decisions Development of Functions Arrays Structure and Unions Pointers File Processing Memory Management Graphics Errors and their Remedies System Software Design Database Design Installation Software Design

    An epic, first-of-its-kind book, entwining leading-edge scientific discovery with the intimate stories of four individual lives, by the Pulitzer Prize–winning New York Times journalist.A terminal cancer patient rises from the grave. A medical marvel defies HIV. Two women with autoimmunity discover their own bodies have turned against them. Matt Richtel's An Elegant Defense uniquely entwines these intimate stories with science’s centuries-long quest to unlock the mysteries of sickness and health, and illuminates the immune system as never before.The immune system is our body’s essential defense network, a guardian vigilantly fighting illness, healing wounds, maintaining order and balance, and keeping us alive. Its legion of microscopic foot soldiers—from T cells to “natural killers”—patrols our body, linked by a nearly instantaneous communications grid. It has been honed by evolution over millennia to face an almost infinite array of threats.For all its astonishing complexity, however, the immune system can be easily compromised by fatigue, stress, toxins, advanced age, and poor nutrition—hallmarks of modern life—and even by excessive hygiene. Paradoxically, it is a fragile wonder weapon that can turn on our own bodies with startling results, leading today to epidemic levels of autoimmune disorders.Richtel effortlessly guides readers on a scientific detective tale winding from the Black Plague to twentieth-century breakthroughs in vaccination and antibiotics, to the cutting-edge laboratories that are revolutionizing immunology—perhaps the most extraordinary and consequential medical story of our time. The foundation that Richtel builds makes accessible revelations about cancer immunotherapy, the microbiome, and autoimmune treatments that are changing millions of lives. An Elegant Defense also captures in vivid detail how these powerful therapies, along with our behavior and environment, interact with the immune system, often for the good but always on a razor’s edge that can throw this remarkable system out of balance.Drawing on his groundbreaking reporting for the New York Times and based on extensive new interviews with dozens of world-renowned scientists, Matt Richtel has produced a landmark book, equally an investigation into the deepest riddles of survival and a profoundly human tale that is movingly brought to life through the eyes of his four main characters, each of whom illuminates an essential facet of our “elegant defense.”

    In How to Clone a Mammoth, Beth Shapiro, evolutionary biologist and pioneer in "ancient DNA" research, walks readers through the astonishing and controversial process of de-extinction. From deciding which species should be restored, to sequencing their genomes, to anticipating how revived populations might be overseen in the wild, Shapiro vividly explores the extraordinary cutting-edge science that is being used--today--to resurrect the past. Journeying to far-flung Siberian locales in search of ice age bones and delving into her own research--as well as those of fellow experts such as Svante Paabo, George Church, and Craig Venter--Shapiro considers de-extinction's practical benefits and ethical challenges. Would de-extinction change the way we live? Is this really cloning? What are the costs and risks? And what is the ultimate goal?Using DNA collected from remains as a genetic blueprint, scientists aim to engineer extinct traits--traits that evolved by natural selection over thousands of years--into living organisms. But rather than viewing de-extinction as a way to restore one particular species, Shapiro argues that the overarching goal should be the revitalization and stabilization of contemporary ecosystems. For example, elephants with genes modified to express mammoth traits could expand into the Arctic, re-establishing lost productivity to the tundra ecosystem.Looking at the very real and compelling science behind an idea once seen as science fiction, How to Clone a Mammoth demonstrates how de-extinction will redefine conservation's future.

    This elegant, humane, and engaging book "captures what we know of the development of what makes us human" (Nature).Visit Armand Marie Leroi on the web: http: //armandleroi.com/index.htmlStepping effortlessly from myth to cutting-edge science,

    In this newly revised edition, chapters have been rewritten to accommodate the impact of computer technology and the Internet, not only on the acquisition and analysis of data, but also on its organization and presentation. Alternatives to the use of radiation have been expanded, and figures and illustrations have been redrawn to reflect changes in laboratory equipment and procedures.

    Evo Devo Evolutionary Developmental Biology is the new science that has finally cracked open the box. Within the pages of his rich and riveting book, Sean B. Carroll explains how we are discovering that complex life is ironically much simpler than anyone ever expected.

    Giant corporations are creating designer crops with strange powers-from cholesterol-reducing soybeans to plants that act as miniature drug factories, churning out everything from vaccines to insulin. They promise great benefits: better health for consumers, more productive agriculture-even an end to world hunger. But the vision has a dark side, one of profit-driven tampering with life and the possible destruction of entire ecosystems. In Lords of the Harvest, Daniel Charles takes us deep inside research labs, farm sheds, and corporate boardrooms to reveal the hidden story behind this agricultural revolution. He tells how a handful of scientists at Monsanto drove biotechnology from the lab into the field, and how the company's opponents are fighting back with every tool available to them, including the cynical manipulation of public fears. A dramatic account of boundless ambition, political intrigue, and the quest for knowledge, Lords of the Harvest is ultimately a story of idealism and of conflicting dreams about the shape of a better world.

    But what happens when we take animal alteration a step further, engineering a cat that glows green under ultraviolet light or cloning the beloved family Labrador? Science has given us a whole new toolbox for tinkering with life. How are we using it?In Frankenstein's Cat, the journalist Emily Anthes takes us from petri dish to pet store as she explores how biotechnology is shaping the future of our furry and feathered friends. As she ventures from bucolic barnyards to a "frozen zoo" where scientists are storing DNA from the planet's most exotic creatures, she discovers how we can use cloning to protect endangered species, craft prosthetics to save injured animals, and employ genetic engineering to supply farms with disease-resistant livestock. Along the way, we meet some of the animals that are ushering in this astonishing age of enhancement, including sensor-wearing seals, cyborg beetles, a bionic bulldog, and the world's first cloned cat.Through her encounters with scientists, conservationists, ethicists, and entrepreneurs, Anthes reveals that while some of our interventions may be trivial (behold: the GloFish), others could improve the lives of many species-including our own. So what does biotechnology really mean for the world's wild things? And what do our brave new beasts tell us about ourselves?With keen insight and her trademark spunk, Anthes highlights both the peril and the promise of our scientific superpowers, taking us on an adventure into a world where our grandest science fiction fantasies are fast becoming reality.

    The Human Genome Project finished sequencing human DNA. It seemed it was only a matter of time until we had all the answers to the secrets of life on this planet. The cutting-edge of biology, however, is telling us that we still don't even know all of the questions. How is it that, despite each cell in your body carrying exactly the same DNA, you don't have teeth growing out of your eyeballs or toenails on your liver? How is it that identical twins share exactly the same DNA and yet can exhibit dramatic differences in the way that they live and grow? It turns out that cells read the genetic code in DNA more like a script to be interpreted than a mould that replicates the same result each time. This is epigenetics and it's the fastest-moving field in biology today. The Epigenetics Revolution traces the thrilling path this discipline has taken over the last twenty years. Biologist Nessa Carey deftly explains such diverse phenomena as how queen bees and ants control their colonies, why tortoiseshell cats are always female, why some plants need a period of cold before they can flower, why we age, develop disease and become addicted to drugs, and much more. Most excitingly, Carey reveals the amazing possibilities for humankind that epigenetics offers for us all - and in the surprisingly near future.