But are there limits to what we can discover about our physical universe?In this very personal journey to the edges of knowledge, Marcus du Sautoy investigates how leading experts in fields from quantum physics and cosmology, to sensory perception and neuroscience, have articulated the current lie of the land. In doing so, he travels to the very boundaries of understanding, questioning contradictory stories and consulting cutting edge data.Is it possible that we will one day know everything? Or are there fields of research that will always lie beyond the bounds of human comprehension? And if so, how do we cope with living in a universe where there are things that will forever transcend our understanding?In What We Cannot Know, Marcus du Sautoy leads us on a thought-provoking expedition to the furthest reaches of modern science. Prepare to be taken to the edge of knowledge to find out if there’s anything we truly cannot know.

    One sought to discover a new planet. Another—an adventuresome female astronomer—fought to prove that science was not anathema to femininity. And a young, megalomaniacal inventor, with the tabloid press fast on his heels, sought to test his scientific bona fides and light the world through his revelations. David Baron brings to three-dimensional life these three competitors—James Craig Watson, Maria Mitchell, and Thomas Edison—and thrillingly re-creates the fierce jockeying of nineteenth-century American astronomy. With spellbinding accounts of train robberies and Indian skirmishes, the mythologized age of the last days of the Wild West comes alive as never before. A magnificent portrayal of America’s dawn as a scientific superpower, American Eclipse depicts a young nation that looked to the skies to reveal its towering ambition and expose its latent genius.

    Wilson has distilled sixty years of teaching into a book for students, young and old. Reflecting on his coming-of-age in the South as a Boy Scout and a lover of ants and butterflies, Wilson threads these twenty-one letters, each richly illustrated, with autobiographical anecdotes that illuminate his career--both his successes and his failures--and his motivations for becoming a biologist. At a time in human history when our survival is more than ever linked to our understanding of science, Wilson insists that success in the sciences does not depend on mathematical skill, but rather a passion for finding a problem and solving it. From the collapse of stars to the exploration of rain forests and the oceans' depths, Wilson instills a love of the innate creativity of science and a respect for the human being's modest place in the planet's ecosystem in his readers.

    He was one of the leading pioneers of the greatest revolution in twentieth-century science: quantum mechanics. The youngest theoretician ever to win the Nobel Prize for Physics, he was also pathologically reticent, strangely literal-minded and legendarily unable to communicate or empathize. Through his greatest period of productivity, his postcards home contained only remarks about the weather.Based on a previously undiscovered archive of family papers, Graham Farmelo celebrates Dirac's massive scientific achievement while drawing a compassionate portrait of his life and work. Farmelo shows a man who, while hopelessly socially inept, could manage to love and sustain close friendship.The Strangest Man is an extraordinary and moving human story, as well as a study of one of the most exciting times in scientific history.'A wonderful book . . . Moving, sometimes comic, sometimes infinitely sad, and goes to the roots of what we mean by truth in science.' Lord Waldegrave, Daily Telegraph

    Now, faced with the threat of nuclear weapons and the effects of climate change, it seems our innate tendencies for violence and invention have led us to a crucial fork in our road. Where did these traits come from? Are they part of our species immutable destiny? Or is there hope for our species’ future if we change? With fascinating facts and his unparalleled readability, Diamond intended his book to improve the world that today’s young people will inherit. Triangle Square’s The Third Chimpanzee for Young People is a book for future generation and the future they’ll help build.

    In all the current highly publicized debates about creationism and its descendant "intelligent design," there is an element of the controversy that is rarely mentioned—the "evidence," the empirical truth of evolution by natural selection. Even Richard Dawkins and Stephen Jay Gould, while extolling the beauty of evolution and examining case studies, have not focused on the evidence itself. Yet the proof is vast, varied, and magnificent, drawn from many different fields of science. Scientists are observing species splitting into two and are finding more and more fossils capturing change in the past—dinosaurs that have sprouted feathers, fish that have grown limbs. Why Evolution Is True weaves together the many threads of modern work in genetics, paleontology, geology, molecular biology, and anatomy that demonstrate the "indelible stamp" of the processes first proposed by Darwin. In crisp, lucid prose accessible to a wide audience, Why Evolution Is True dispels common misunderstandings and fears about evolution and clearly confirms that this amazing process of change has been firmly established as a scientific truth.

      In 1875, tuberculosis was the deadliest disease in the world, accountable for a third of all deaths. A diagnosis of TB—often called consumption—was a death sentence. Then, in a triumph of medical science, a German doctor named Robert Koch deployed an unprecedented scientific rigor to discover the bacteria that caused TB. Koch soon embarked on a remedy—a remedy that would be his undoing.   When Koch announced his cure for consumption, Arthur Conan Doyle, then a small-town doctor in England and sometime writer, went to Berlin to cover the event. Touring the ward of reportedly cured patients, he was horrified. Koch’s "remedy" was either sloppy science or outright fraud.   But to a world desperate for relief, Koch’s remedy wasn’t so easily dismissed. As Europe’s consumptives descended upon Berlin, Koch urgently tried to prove his case. Conan Doyle, meanwhile, returned to England determined to abandon medicine in favor of writing. In particular, he turned to a character inspired by the very scientific methods that Koch had formulated: Sherlock Holmes.   Capturing the moment when mystery and magic began to yield to science, The Remedy chronicles the stunning story of how the germ theory of disease became a true fact, how two men of ambition were emboldened to reach for something more, and how scientific discoveries evolve into social truths.

    As she sped through the pages, she became enthralled by the intense drama behind the competition to discover the code of life. Even though her high school counselor told her girls didn’t become scientists, she decided she would.Driven by a passion to understand how nature works and to turn discoveries into inventions, she would help to make what the book’s author, James Watson, told her was the most important biological advance since his co-discovery of the structure of DNA. She and her collaborators turned ​a curiosity ​of nature into an invention that will transform the human race: an easy-to-use tool that can edit DNA. Known as CRISPR, it opened a brave new world of medical miracles and moral questions. The development of CRISPR and the race to create vaccines for coronavirus will hasten our transition to the next great innovation revolution. The past half-century has been a digital age, based on the microchip, computer, and internet. Now we are entering a life-science revolution. Children who study digital coding will be joined by those who study genetic code. Should we use our new evolution-hacking powers to make us less susceptible to viruses? What a wonderful boon that would be! And what about preventing depression? Hmmm…Should we allow parents, if they can afford it, to enhance the height or muscles or IQ of their kids? After helping to discover CRISPR, Doudna became a leader in wrestling with these moral issues and, with her collaborator Emmanuelle Charpentier, won the Nobel Prize in 2020.

    "One of today's best popularizers of science." —Kirkus Reviews.Loyal readers of the monthly "Universe" essays in Natural History magazine have long recognized Neil deGrasse Tyson's talent for guiding them through the mysteries of the cosmos with stunning clarity and almost childlike enthusiasm. Here, Tyson compiles his favorite essays across a myriad of cosmic topics. The title essay introduces readers to the physics of black holes by explaining the gory details of what would happen to your body if you fell into one. "Holy Wars" examines the needless friction between science and religion in the context of historical conflicts. "The Search for Life in the Universe" explores astral life from the frontiers of astrobiology. And "Hollywood Nights" assails the movie industry's feeble efforts to get its night skies right. Known for his ability to blend content, accessibility, and humor, Tyson is a natural teacher who simplifies some of the most complex concepts in astrophysics while simultaneously sharing his infectious excitement about our universe.

    Astrophysicist Adam Frank traces the question of alien life and intelligence from the ancient Greeks to the leading thinkers of our own time, and shows how we as a civilization can only hope to survive climate change if we recognize what science has recently discovered: that we are just one of ten billion trillion planets in the Universe, and it’s highly likely that many of those planets hosted technologically advanced alien civilizations. What’s more, each of those civilizations must have faced the same challenge of civilization-driven climate change.Written with great clarity and conviction, Light of the Stars builds on the inspiring work of pioneering scientists such as Frank Drake and Carl Sagan, whose work at the dawn of the space age began building the new science of astrobiology; Jack James, the Texas-born engineer who drove NASA’s first planetary missions to success; Vladimir Vernadsky, the Russian geochemist who first envisioned the Earth’s biosphere; and James Lovelock and Lynn Margulis, who invented Gaia theory. Frank recounts the perilous journey NASA undertook across millions of miles of deep space to get its probes to Venus and Mars, yielding our first view of the cosmic laws of planets and climate that changed our understanding of our place in the universe.Thrilling science at the grandest of scales, Light of the Stars explores what may be the largest question of all: What can the likely presence of life on other worlds tell us about our own fate?

    And before there were fish in the sea, there were cephalopods - the ancestors of modern squid and Earth’s first truly substantial animals. Cephalopods became the first creatures to rise from the seafloor, essentially inventing the act of swimming. With dozens of tentacles and formidable shells, they presided over an undersea empire for millions of years. But when fish evolved jaws, the ocean’s former top predator became its most delicious snack. Cephalopods had to step up their game. Many species streamlined their shells and added defensive spines, but these enhancements only provided a brief advantage. Some cephalopods then abandoned the shell entirely, which opened the gates to a flood of evolutionary innovations: masterful camouflage, fin-supplemented jet propulsion, perhaps even dolphin-like intelligence. Squid Empire is an epic adventure spanning hundreds of millions of years, from the marine life of the primordial ocean to the calamari on tonight’s menu. Anyone who enjoys the undersea world—along with all those obsessed with things prehistoric—will be interested in the sometimes enormous, often bizarre creatures that ruled the seas long before the first dinosaurs.

    For more than two centuries, our understanding of the laws of nature expanded rapidly. But today, despite our best efforts, we know nothing more about these laws than we knew in the 1970s. Why is physics suddenly in trouble? And what can we do about it?One of the major problems, according to Smolin, is string theory: an ambitious attempt to formulate a “theory of everything” that explains all the particles and forces of nature and how the universe came to be. With its exotic new particles and parallel universes, string theory has captured the public’s imagination and seduced many physicists.But as Smolin reveals, there’s a deep flaw in the theory: no part of it has been tested, and no one knows how to test it. In fact, the theory appears to come in an infinite number of versions, meaning that no experiment will ever be able to prove it false. As a scientific theory, it fails. And because it has soaked up the lion’s share of funding, attracted some of the best minds, and effectively penalized young physicists for pursuing other avenues, it is dragging the rest of physics down with it.With clarity, passion, and authority, Smolin charts the rise and fall of string theory and takes a fascinating look at what will replace it. A group of young theorists has begun to develop exciting ideas that, unlike string theory, are testable. Smolin not only tells us who and what to watch for in the coming years, he offers novel solutions for seeking out and nurturing the best new talent—giving us a chance, at long last, of finding the next Einstein.

    Physician, researcher, and award-winning science writer, Siddhartha Mukherjee examines cancer with a cellular biologist’s precision, a historian’s perspective, and a biographer’s passion. The result is an astonishingly lucid and eloquent chronicle of a disease humans have lived with - and perished from - for more than five thousand years. The story of cancer is a story of human ingenuity, resilience, and perseverance, but also of hubris, paternalism, and misperception. Mukherjee recounts centuries of discoveries, setbacks, victories, and deaths, told through the eyes of his predecessors and peers, training their wits against an infinitely resourceful adversary that, just three decades ago, was thought to be easily vanquished in an all-out “war against cancer.” The book reads like a literary thriller with cancer as the protagonist. From the Persian Queen Atossa, whose Greek slave cut off her malignant breast, to the nineteenth-century recipients of primitive radiation and chemotherapy to Mukherjee’s own leukemia patient, Carla, The Emperor of All Maladies is about the people who have soldiered through fiercely demanding regimens in order to survive—and to increase our understanding of this iconic disease. Riveting, urgent, and surprising, The Emperor of All Maladies provides a fascinating glimpse into the future of cancer treatments. It is an illuminating book that provides hope and clarity to those seeking to demystify cancer.

    Scientists around the world are currently monitoring the sixth extinction, predicted to be the most devastating extinction event since the asteroid impact that wiped out the dinosaurs. This time around, the cataclysm is us. In prose that is at once frank, entertaining, and deeply informed, The New Yorker writer Elizabeth Kolbert tells us why and how human beings have altered life on the planet in a way no species has before. Interweaving research in half a dozen disciplines, descriptions of the fascinating species that have already been lost, and the history of extinction as a concept, Kolbert provides a moving and comprehensive account of the disappearances occurring before our very eyes. She shows that the sixth extinction is likely to be mankind's most lasting legacy, compelling us to rethink the fundamental question of what it means to be human.

    Feynman's contributions to twentieth-century physics, but few realize how engaged he was with the world around him -- how deeply and thoughtfully he considered the religious, political, and social issues of his day. Now, a wonderful book -- based on a previously unpublished, three-part public lecture he gave at the University of Washington in 1963 -- shows us this other side of Feynman, as he expounds on the inherent conflict between science and religion, people's distrust of politicians, and our universal fascination with flying saucers, faith healing, and mental telepathy. Here we see Feynman in top form: nearly bursting into a Navajo war chant, then pressing for an overhaul of the English language (if you want to know why Johnny can't read, just look at the spelling of "friend"); and, finally, ruminating on the death of his first wife from tuberculosis. This is quintessential Feynman -- reflective, amusing, and ever enlightening.