In Under the Knife, surgeon Arnold Van de Laar uses his own experience and expertise to tell the witty history of the past, present and future of surgery.From the story of the desperate man from seventeenth-century Amsterdam who grimly cut a stone out of his own bladder to Bob Marley's deadly toe, Under the Knife offers all kinds of fascinating and unforgettable insights into medicine and history via the operating theatre.What happens during an operation? How does the human body respond to being attacked by a knife, a bacterium, a cancer cell or a bullet? And, as medical advances continuously push the boundaries of what medicine can cure, what are the limits of surgery?From the dark centuries of bloodletting and of amputations without anaesthetic to today's sterile, high-tech operating theatres, Under the Knife is both a rich cultural history, and a modern anatomy class for us all.

    At the end of the nineteenth century, serial murderer Joseph Vacher, known and feared as "The Killer of Little Shepherds," terrorized the French countryside. He eluded authorities for years--until he ran up against prosecutor Emile Fourquet and Dr. Alexandre Lacassagne, the era's most renowned criminologist. The two men--intelligent and bold--typified the Belle Epoque, a period of immense scientific achievement and fascination with science's promise to reveal the secrets of the human condition. With high drama and stunning detail, Douglas Starr revisits Vacher's infamous crime wave, interweaving the story of how Lacassagne and his colleagues were developing forensic science as we know it. We see one of the earliest uses of criminal profiling, as Fourquet painstakingly collects eyewitness accounts and constructs a map of Vacher's crimes. We follow the tense and exciting events leading to the murderer's arrest. And we witness the twists and turns of the trial, celebrated in its day. In an attempt to disprove Vacher's defense by reason of insanity, Fourquet recruits Lacassagne, who in the previous decades had revolutionized criminal science by refining the use of blood-spatter evidence, systematizing the autopsy, and doing groundbreaking research in psychology. Lacassagne's efforts lead to a gripping courtroom denouement. "The Killer of Little Shepherds" is an important contribution to the history of criminal justice, impressively researched and thrillingly told.

    secretary of stateA Fascist, observes Madeleine Albright, “is someone who claims to speak for a whole nation or group, is utterly unconcerned with the rights of others, and is willing to use violence and whatever other means are necessary to achieve the goals he or she might have.” The twentieth century was defined by the clash between democracy and Fascism, a struggle that created uncertainty about the survival of human freedom and left millions dead. Given the horrors of that experience, one might expect the world to reject the spiritual successors to Hitler and Mussolini should they arise in our era. In Fascism: A Warning, Madeleine Albright draws on her experiences as a child in war-torn Europe and her distinguished career as a diplomat to question that assumption.Fascism, as she shows, not only endured through the twentieth century but now presents a more virulent threat to peace and justice than at any time since the end of World War II.  The momentum toward democracy that swept the world when the Berlin Wall fell has gone into reverse.  The United States, which historically championed the free world, is led by a president who exacerbates division and heaps scorn on democratic institutions.  In many countries, economic, technological, and cultural factors are weakening the political center and empowering the extremes of right and left.  Contemporary leaders such as Vladimir Putin and Kim Jong-un are employing many of the tactics used by Fascists in the 1920s and 30s.Fascism: A Warning is a book for our times that is relevant to all times.  Written  by someone who has not only studied history but helped to shape it, this call to arms teaches us the lessons we must understand and the questions we must answer if we are to save ourselves from repeating the tragic errors of the past.

    But American Overdose exposes the powerful forces they were up against, including the pharmaceutical industry's coopting of the Food and Drug Administration and Congress in the drive to push painkillers--resulting in the resurgence of heroin cartels in the American heartland. McGreal tells the story, in terms both broad and intimate, of people hit by a catastrophe they never saw coming. Years in the making, its ruinous consequences will stretch years into the future.

    But what about Tillie Klimek, Moulay Hassan, and Kate Bender? The narrative we're comfortable with is one where women are the victims of violent crime-not the perpetrators. In fact, serial killers are thought to be so universally male that, in 1998, FBI profiler Roy Hazelwood infamously declared that There are no female serial killers. Inspired by Telfer's Jezebel column of the same name, Lady Killers disputes that claim and offers fourteen gruesome examples as evidence. Although largely forgotten by history, female serial killers rival their male counterparts in cunning, cruelty, and appetite. Each chapter explores the crimes and history of a different female serial killer and then proceeds to unpack her legacy and her portrayal in the media as well as the stereotypes and sexist cliches that inevitably surround her.

    His passing on March 6, 1900, would have been unremarkable if a city health officer hadn’t noticed a swollen black lymph node on his groin—a sign of bubonic plague. Empowered by racist pseudoscience, officials rushed to quarantine Chinatown while doctors examined Wong’s tissue for telltale bacteria. If the devastating disease was not contained, San Francisco would become the American epicenter of an outbreak that had already claimed ten million lives worldwide.To local press, railroad barons, and elected officials, such a possibility was inconceivable—or inconvenient. As they mounted a cover-up to obscure the threat, ending the career of one of the most brilliant scientists in the nation in the process, it fell to federal health officer Rupert Blue to save a city that refused to be rescued. Spearheading a relentless crusade for sanitation, Blue and his men patrolled the squalid streets of fast-growing San Francisco, examined gory black buboes, and dissected diseased rats that put the fate of the entire country at risk.In the tradition of Erik Larson and Steven Johnson, Randall spins a spellbinding account of Blue’s race to understand the disease and contain its spread—the only hope of saving San Francisco, and the nation, from a gruesome fate.

    Jen Gunter now delivers the definitive book on vaginal health, answering the questions you've always had but were afraid to ask--or couldn't find the right answers to. She has been called Twitter's resident gynecologist, the Internet's OB/GYN, and one of the fiercest advocates for women's health...and she's here to give you the straight talk on the topics she knows best.Does eating sugar cause yeast infections? Does pubic hair have a function? Should you have a vulvovaginal care regimen?Will your vagina shrivel up if you go without sex?What's the truth about the HPV vaccine?So many important questions, so much convincing, confusing, contradictory misinformation! In this age of click bait, pseudoscience, and celebrity-endorsed products, it's easy to be overwhelmed--whether it's websites, advice from well-meaning friends, uneducated partners, and even healthcare providers. So how do you separate facts from fiction? OB-GYN Jen Gunter, an expert on women's health--and the internet's most popular go-to doc--comes to the rescue with a book that debunks the myths and educates and empowers women. From reproductive health to the impact of antibiotics and probiotics, and the latest trends, including vaginal steaming, vaginal marijuana products, and jade eggs, Gunter takes us on a factual, fun-filled journey. Discover the truth about:- The vaginal microbiome - Genital hygiene, lubricants, and hormone myths and fallacies - How diet impacts vaginal health - Stem cells and the vagina - Cosmetic vaginal surgery - What changes to expect during pregnancy, after childbirth, and through menopause - How medicine fails women by dismissing symptomsPlus: - Thongs vs. lace: the best underwear for vaginal health - How to select a tampon - The full glory of the clitoris and the myth of the G Spot... And so much more. Whether you're a twenty-six-year-old worried that her labia are "uncool" or a sixty-six-year-old dealing with painful sex, this comprehensive guide is sure to become a lifelong trusted resource.

    She takes us by her side down hospital corridors to visit the wards and meet her unforgettable patients.In the neonatal unit, premature babies fight for their lives, hovering at the very edge of survival, like tiny Emmanuel, wrapped up in a sandwich bag. On the cancer wards, the nurses administer chemotherapy and, long after the medicine stops working, something more important--which Watson learns to recognize when her own father is dying of cancer. In the pediatric intensive care unit, the nurses wash the hair of a little girl to remove the smell of smoke from the house fire. The emergency room is overcrowded as ever, with waves of alcohol and drug addicted patients as well as patients like Betty, a widow suffering chest pain, frail and alone. And the stories of the geriatric ward--Gladys and older patients like her--show the plight of the most vulnerable members of our society.

    The first small cities formed not only the cradle of civilization, but the spawning ground for the earliest viral epidemics, the first opportunity for viruses to find a home in the human herd. This is a story of fear and ignorance, as everything from demons and the wrath of the gods to minority groups have been blamed for epidemics from smallpox to yellow fever to AIDS. It is a story of grief and heartbreak, as hundreds of thousands, sometimes millions, are wiped out in a single year. And it is a story of great bravery and sacrifice, as doctors and nurses put themselves in harm's way to combat yellow fever in Memphis and Ebola in Zaire, and as researchers risk their own lives to test theories of vaccines and the transmission of disease. Now, in Viruses, Plagues, and History, Michael B. A. Oldstone tells all these stories as he illuminates the history of the devastating diseases that have tormented humanity.Oldstone focuses his tale on a few of the most famous viruses humanity has battled, beginning with some we have effectively defeated, such as smallpox, polio, and measles. Nearly 300 million people were killed by smallpox in this century alone -- more than were killed in all the wars of the twentieth century combined. The author presents a vivid account of the long campaign against the virus, the insightful work of Edward Jenner, who created the smallpox vaccine from cowpox virus in 1796, and the monumental efforts of D. A. Henderson and an army of W.H.O. health care workers to finally eradicate smallpox. The smallpox virus remains the only organism that we have deliberately pushed to complete extinction in the wild.Oldstone then describes the fascinating viruses that have captured headlines in more recent years: Ebola and other hemorrhagic fevers, which literally turn their victims' organs to a bloody pulp; the Hantavirus outbreaks in the southwestern United States and elsewhere; mad cow disease, a frightening illness made worse by government mishandling and secrecy; and, of course, AIDS, often called the plague of our time. And he tells us of the many scientists watching and waiting even now for the next great plague, monitoring influenza strains to see whether the deadly variant from 1918 -- a viral strain that killed over 20 million people in 1918-1919, more than twice the military and civilian casualties of the First World War -- will make a comeback.Viruses have enormous power. They have wiped out cities, brought down dynasties, and helped destroy civilizations. But, as Michael Oldstone reveals, scientific research has given us the power to tame many of these viruses as well. Viruses, Plagues, and History shows us the panorama of humanity's long-standing conflict with our unseen viral enemies, from our successes to our continuing struggles. Oldstone's book is a vivid history of a fascinating field, and a highly reliable dispatch from a worker on the frontiers of this ongoing campaign.

    Operations on the brain carry grave risks. Every day, leading neurosurgeon Henry Marsh must make agonizing decisions, often in the face of great urgency and uncertainty.If you believe that brain surgery is a precise and exquisite craft, practiced by calm and detached doctors, this gripping, brutally honest account will make you think again. With astonishing compassion and candor, Marsh reveals the fierce joy of operating, the profoundly moving triumphs, the harrowing disasters, the haunting regrets, and the moments of black humor that characterize a brain surgeon's life.Do No Harm provides unforgettable insight into the countless human dramas that take place in a busy modern hospital. Above all, it is a lesson in the need for hope when faced with life's most difficult decisions.

    But two men—John Chatterton and John Mattera—are willing to risk everything to find the Golden Fleece, the ship of the infamous pirate Joseph Bannister. At large during the Golden Age of Piracy in the seventeenth century, Bannister’s exploits would have been more notorious than Blackbeard’s, more daring than Kidd’s, but his story, and his ship, have been lost to time. If Chatterton and Mattera succeed, they will make history—it will be just the second time ever that a pirate ship has been discovered and positively identified. Soon, however, they realize that cutting-edge technology and a willingness to lose everything aren’t enough to track down Bannister’s ship. They must travel the globe in search of historic documents and accounts of the great pirate’s exploits, face down dangerous rivals, battle the tides of nations and governments and experts. But it’s only when they learn to think and act like pirates—like Bannister—that they become able to go where no pirate hunters have gone before. Fast-paced and filled with suspense, fascinating characters, history, and adventure, Pirate Hunters is an unputdownable story that goes deep to discover truths and souls long believed lost.Advance praise for Pirate Hunters “A great thriller full of tough guys and long odds . . . and: It’s all true.”—Lee Child “Action and adventure on land and sea—you can’t ask for more. But Robert Kurson raises the ante in Pirate Hunters with an array of mystery and a fleet of colorful characters spanning four centuries. This is a great summer read!”—Michael Connelly “Pirate Hunters is a fantastic book, an utterly engrossing and satisfying read. It tells the story of the hunt for the rare wreck of a pirate ship, which had been captained by one of the most remarkable pirates in history. This is a real-life Treasure Island, complete with swashbuckling, half-crazy treasure hunters and vivid Caribbean settings—a story for the ages.”—Douglas Preston “A terrific read. I was pulled in from page one. Kurson brings us face to face with some of the most swashbuckling pirates ever to sail the Caribbean, even as he takes us underwater on a high-tech quest to discover the relics they left behind.”—Daniel James Brown “There’s nothing in the world like buried treasure—and people hungry and obsessed enough to risk their lives for it. Pirate Hunters isn’t just a good story—it’s a true one. Searching for the souls of its explorers, it takes you to the far tip of the plank and plunges you deep to the bottom of the ocean.”—Brad Meltzer “Pirate Hunters is a gripping account of two courageous divers’ quest to uncover the shipwrecked vessel of Joseph Bannister, one of history’s most infamous pirates. Robert Kurson will keep you on the edge of your seat in this high-stakes journey around the globe that ultimately teaches these explorers about much more than an old ship.”—Sen. John McCain “Kurson’s own enthusiasm, combined with his copious research and an eye for detail, makes for one of the most mind-blowing pirate stories of recent memory.”—Publishers Weekly

    But the famous and infamous have been thrilling, titillating, and outraging us for much longer than we might realise. Whether it was the scandalous Lord Byron, whose poetry sent female fans into an erotic frenzy; or the cheetah-owning, coffin-sleeping, one-legged French actress Sarah Bernhardt, who launched a violent feud with her former best friend; or Edmund Kean, the dazzling Shakespearean actor whose monstrous ego and terrible alcoholism saw him nearly murdered by his own audience - the list of stars whose careers burned bright before the Age of Television is extensive and thrillingly varied.Celebrities could be heroes or villains; warriors or murderers; brilliant talents, or fraudsters with a flair for fibbing; trendsetters, wilful provocateurs, or tragic victims marketed as freaks of nature. Some craved fame while others had it forced upon them. A few found fame as small children, some had to wait decades to get their break. But uniting them all is the shared origin point: since the early 1700s, celebrity has been one of the most emphatic driving forces in popular culture; it is a lurid cousin to Ancient Greek ideas of glorious and notorious reputation, and its emergence helped to shape public attitudes to ethics, national identity, religious faith, wealth, sexuality, and gender roles.In this ambitious history, that spans the Bronze Age to the coming of Hollywood's Golden Age, Greg Jenner assembles a vibrant cast of over 125 actors, singers, dancers, sportspeople, freaks, demigods, ruffians, and more, in search of celebrity's historical roots. He reveals why celebrity burst into life in the early eighteenth century, how it differs to ancient ideas of fame, the techniques through which it was acquired, how it was maintained, the effect it had on public tastes, and the psychological burden stardom could place on those in the glaring limelight. DEAD FAMOUS is a surprising, funny, and fascinating exploration of both a bygone age and how we came to inhabit our modern, fame obsessed society.

    An act of terrorism of staggering efficiency, it fulfilled its every aim: it would liberate Bosnia from Habsburg rule and it created a powerful new Serbia, but it also brought down four great empires, killed millions of men and destroyed a civilization. What made a seemingly prosperous and complacent Europe so vulnerable to the impact of this assassination? In The Sleepwalkers Christopher Clark retells the story of the outbreak of the First World War and its causes. Above all, it shows how the failure to understand the seriousness of the chaotic, near genocidal fighting in the Balkans would drag Europe into catastrophe.

    And sugar is at the root of these, and other, critical society-wide, health-related problems. With his signature command of both science and straight talk, Gary Taubes delves into Americans' history with sugar: its uses as a preservative, as an additive in cigarettes, the contemporary overuse of high-fructose corn syrup. He explains what research has shown about our addiction to sweets. He clarifies the arguments against sugar, corrects misconceptions about the relationship between sugar and weight loss; and provides the perspective necessary to make informed decisions about sugar as individuals and as a society.

    With the latest findings about the mental and physical benefits of exercise, personal stories from scientists and laypeople alike, as well as researched-based prescriptions for readers, Gretchen Reynolds shows what kind of exercise—and how much—is necessary to stay healthy, get fit, and attain a smaller jeans size. Inspired by Reynolds's wildly popular “Phys Ed” column for The New York Times, this book explains how exercise affects the body in distinct ways and provides the tools readers need to achieve their fitness goals, whether that's a faster 5K or staying trim.