She was a poor Southern tobacco farmer who worked the same land as her enslaved ancestors, yet her cells—taken without her knowledge—became one of the most important tools in medicine. The first “immortal” human cells grown in culture, they are still alive today, though she has been dead for more than sixty years. If you could pile all HeLa cells ever grown onto a scale, they’d weigh more than 50 million metric tons—as much as a hundred Empire State Buildings. HeLa cells were vital for developing the polio vaccine; uncovered secrets of cancer, viruses, and the atom bomb’s effects; helped lead to important advances like in vitro fertilization, cloning, and gene mapping; and have been bought and sold by the billions.Yet Henrietta Lacks remains virtually unknown, buried in an unmarked grave.Now Rebecca Skloot takes us on an extraordinary journey, from the “colored” ward of Johns Hopkins Hospital in the 1950s to stark white laboratories with freezers full of HeLa cells; from Henrietta’s small, dying hometown of Clover, Virginia — a land of wooden quarters for enslaved people, faith healings, and voodoo — to East Baltimore today, where her children and grandchildren live and struggle with the legacy of her cells.Henrietta’s family did not learn of her “immortality” until more than twenty years after her death, when scientists investigating HeLa began using her husband and children in research without informed consent. And though the cells had launched a multimillion-dollar industry that sells human biological materials, her family never saw any of the profits. As Rebecca Skloot so brilliantly shows, the story of the Lacks family — past and present — is inextricably connected to the history of experimentation on African Americans, the birth of bioethics, and the legal battles over whether we control the stuff we are made of.Over the decade it took to uncover this story, Rebecca became enmeshed in the lives of the Lacks family—especially Henrietta’s daughter Deborah, who was devastated to learn about her mother’s cells. She was consumed with questions: Had scientists cloned her mother? Did it hurt her when researchers infected her cells with viruses and shot them into space? What happened to her sister, Elsie, who died in a mental institution at the age of fifteen? And if her mother was so important to medicine, why couldn’t her children afford health insurance?Intimate in feeling, astonishing in scope, and impossible to put down, The Immortal Life of Henrietta Lacks captures the beauty and drama of scientific discovery, as well as its human consequences.

    My older sister, Helen, came to my room, took me by the hand, and sat me down on the bed. She opened her mouth to say something, but then her face flushed, and she turned her head to look out the window. After a second, she squeezed my hand and looked back in my eyes. She said, “You’ve always been a good girl, Maude, and done what I told you. Now, you’re going to be a married woman, and he will be the head of the house. When you go home tonight after your party, no matter what he wants to do to you, you have to let him do it. Do you understand?"I didn’t understand, but I nodded my head anyway. It sounded strange to me, the way so many things did. I would do what she told me. I didn’t have a choice, any more than I had a choice in being born.

    Fox: Actor. Husband. Father. Activist. But readers of Always Looking Up will soon add another to the list: Optimist. Michael writes about the hard-won perspective that helped him see challenges as opportunities. Instead of building walls around himself, he developed a personal policy of engagement and discovery: an emotional, psychological, intellectual, and spiritual outlook that has served him throughout his struggle with Parkinson's disease. Michael's exit from a very demanding, very public arena offered him the time-and the inspiration-to open up new doors leading to unexpected places. One door even led him to the center of his own family, the greatest destination of all. The last ten years, which is really the stuff of this book, began with such a loss: my retirement from Spin City. I found myself struggling with a strange new dynamic: the shifting of public and private personas. I had been Mike the actor, then Mike the actor with PD. Now was I just Mike with PD Parkinson's had consumed my career and, in a sense, had become my career. But where did all of this leave Me? I had to build a new life when I was already pretty happy with the old one. .Always Looking Up is a memoir of this last decade, told through the critical themes of Michael's life: work, politics, faith, and family. The book is a journey of self-discovery and reinvention, and a testament to the consolations that protect him from the ravages of Parkinson's.With the humor and wit that captivated fans of his first book, Lucky Man, Michael describes how he became a happier, more satisfied person by recognizing the gifts of everyday life.

    Now she’s distilled what she’s learned about how to live a more exhilarating and meaningful life into three words: find the good. It’s that simple--and that hard. Quirky and profound, individual and universal, Find the Good offers up short chapters that help us unlearn the habit--and it is a habit--of seeing only the negatives. Lende reminds us that we can choose to see any event--starting a new job or being laid off from an old one, getting married or getting divorced--as an opportunity to find the good. As she says, “We are all writing our own obituary every day by how we live. The best news is that there’s still time for additions and revisions before it goes to press.” Ever since Algonquin published her first book, the New York Times bestseller If You Lived Here, I’d Know Your Name, Heather Lende has been praised for her storytelling talent and her plainspoken wisdom. The Los Angeles Times called her “part Annie Dillard, part Anne Lamott,” and that comparison has never been more apt as she gives us a fresh, positive perspective from which to view our relationships, our obligations, our priorities, our community, and our world. An antidote to the cynicism and self-centeredness that we are bombarded with every day in the news, in our politics, and even at times in ourselves, Find the Good helps us rediscover what’s right with the world. “Heather Lende’s small town is populated with big hearts--she finds them  on the beach, walking her granddaughters, in the stories of ordinary peoples’ lives, and knits them into unforgettable tales. Find the Good is a treasure.” —Jo-Ann Mapson, author of Owen’s Daughter “Find the Good is excellent company in unsteady times . . . Heather Lende is the kind of person you want to sit across the kitchen table from on a rainy afternoon with a bottomless cup of tea. When things go wrong, when things go right, her quiet, commonsense wisdom, self-examining frankness, and good-natured humor offer a chance to reset, renew, rebalance.”  —Pam Houston, author of Contents May Have Shifted “With gentle humor and empathy [Lende] introduces a number of people who provide examples of how to live well . . . [Find the Good] is simple yet profound.”  —Booklist “In this cynical world, Find the Good is a tonic, a literary wellspring, which will continue to run, and nurture, even in times of drought. What a brave and beautiful thing Heather Lende has made with this book.” —John Straley, Shamus Award winner and former writer laureate of Alaska “Heather Lende is a terrific writer and terrific company: intimate, authentic, and as quirky as any of her subjects.” —Marilyn Johnson, author of The Dead Beat

    You can’t help but fall for Chika. A page-turner that will no doubt become a classic.” --Mary Karr, author of The Liars’ Club and The Art of Memoir From the #1 New York Times bestselling author of Tuesdays With Morrie comes Mitch Albom’s most personal story to date: an intimate and heartwarming memoir about what it means to be a family and the young Haitian orphan whose short life would forever change his heart.  Chika Jeune was born three days before the devastating earthquake that decimated Haiti in 2010. She spent her infancy in a landscape of extreme poverty, and when her mother died giving birth to a baby brother, Chika was brought to The Have Faith Haiti Orphanage that Albom operates in Port Au Prince. With no children of their own, the forty-plus children who live, play, and go to school at the orphanage have become family to Mitch and his wife, Janine. Chika’s arrival makes a quick impression. Brave and self-assured, even as a three-year-old, she delights the other kids and teachers. But at age five, Chika is suddenly diagnosed with something a doctor there says, “No one in Haiti can help you with.” Mitch and Janine bring Chika to Detroit, hopeful that American medical care can soon return her to her homeland. Instead, Chika becomes a permanent part of their household, and their lives, as they embark on a two-year, around-the-world journey to find a cure. As Chika’s boundless optimism and humor teach Mitch the joys of caring for a child, he learns that a relationship built on love, no matter what blows it takes, can never be lost. Told in hindsight, and through illuminating conversations with Chika herself, this is Albom at his most poignant and vulnerable. Finding Chika is a celebration of a girl, her adoptive guardians, and the incredible bond they formed—a devastatingly beautiful portrait of what it means to be a family, regardless of how it is made.

    New Life, No Instructions is about the surprising way life can begin again, at any age.   “What do you do when the story changes in midlife? When a tale you have told yourself turns out to be a little untrue, just enough to throw the world off-kilter? It’s like leaving the train at the wrong stop: You are still you, but in a new place, there by accident or grace, and you will need your wits about you to proceed.   “Any change that matters, or takes, begins as immeasurably small. Then it accumulates, moss on stone, and after a few thousand years of not interfering, you have a glen, or a waterfall, or a field of hope where sorrow used to be.   “I suppose all of us consider our loved ones extraordinary; that is one of the elixirs of attachment. But over the months of pain and disrepair of that winter, I felt something that made the grimness tolerable: I felt blessed by the tribe I was part of. Here I was, supposedly solo, and the real truth was that I had a force field of connection surrounding me.   “Most of all I told this story because I wanted to say something about hope and the absence of it, and how we keep going anyway. About second chances, and how they’re sometimes buried amid the dross, even when you’re poised for the downhill grade. The narrative can always turn out to be a different story from what you expected.”

    Accustomed to their independent routines, they will have to reform both their lives to accommodate the enervating illness. As Jennifer’s sense of self falls away, however, the couple is struck again. Her husband’s “frozen shoulder” all but locks one side of his upper body, leaving him in excruciating pain, partially immobilized, and as dependent on Jennifer as she is on him. But their needs are not in competition. In communion and reciprocal caregiving, they learn to love—and to explore—each other anew.

    I am the one who came out on the other side of childhood; she is the one who searched for the door."In the tradition of The Glass Castle comes a debut memoir about a woman’s hopeful life despite the sad results of her mother’s choices. Moonlight on Linoleum is an affecting story of a girl who rose above her circumstances to become an early and faithful caretaker to her five siblings. It is about the power one finds in sisterhood to thrive in a difficult and ever-changing landscape as the girls bond in unconditional love despite constant upheaval and uncertainty. In these pages, Teresa Helwig crafts a moving portrait of a mother she loved completely even as she struggled to understand her. "Putting myself in Mama's shoes, which were most often white moccasins molded in the shape of her size seven-and-a-half foot, I see an eighteen-year-old girl with two children, one of them still a baby. . . . Her former husband is in Korea, drafted after their divorce; she has a sister who disappears from time to time, leaving yet another child in her care; she has no money, no high-school diploma, and a mother unhappy to have her home." Teresa and her sisters, who were added regularly throughout the 1950s and '60s, grew up with with their charismatic, troubled, and very young mother, Carola. Because of their stepfather’s roving job as in the oil fields, they moved frequently from town to town in the American West. The girls were often separated and left behind with relatives and never knew what their unstable mother would do next. Missing her mother became a habit for Teresa; one summer Carola dropped off her two daughters at her ex's family farm."If there were an idyllic summer of childhood, it was that summer on the Iowa farm. Yet, if I had to choose a time when I felt most forsaken by my mother, it was also that summer. Even back then, I was acutely aware of the paradox. On the outside, by day, I was like the morning glory vine twining around the back fence. Every day opened to a life I loved on the land. I reveled in and relished the absolute freedom and abandon of being turned loose in Eden.      "But then, each evening, after the sun set and the dinner dishes had been hand-washed and dried, I became like the moonflower vine climbing up the weathered boards on the side of the garage. The moonflower opens its large fragrant blooms at night; they shimmer like moonlight and sweeten the night air.     "I evolved a ritual at bedtime before crawling into my bed . . . I held Mama's Polaroid picture to my heart. I love you. Please come get us soon. I want to be with you more than I want to be anywhere else. These were my prayers, my blooms that opened to the night. Then I pursed my lips against the cool glass and kissed her smiling face goodnight."There were good times too: Carola made fudge for the girls during rainstorms, helped Teresa's cat deliver kittens, and taught her to play "You Are My Sunshine" on a toy piano. But when her husband was out working on the oil fields, Carola, who had married at fourteen, began to fill her time with men she met in the various towns her roving family moved to. She referred to her secret dating life as "going to Timbuktu," leaving Teresa in charge of her siblings. As Carola roamed and eventually developed crippling migraines, Teresa became a replacement mommy before her own childhood was fully in swing. Stress, guilt, and recurring nightmares marked her days and nights."In addition to the amphetamines [for weight loss], Mama was now taking barbiturates for her migraines. Her moods began to yo-yo. She became as hard to predict as the weather. When Daddy was out of town and Mama was in one of her fogs, I learned to fend for myself. And, being the oldest, I learned to fend for my sisters, too . . . It was around this time I came to realize a hard truth. Once your sisters begin looking up to you, as if you really could save them from being poisoned, as if you know a way out of a dark cave, there's no going back. You'll draw your last breath, trying to find that door to the Lost City of Enchantment, because you can't bear to let them down."Yet, even in the face of adversity, Teresa found beauty in the small moments: resting in the boughs of her favorite oak tree, savoring the freedom she found on her grandparents’ farm, and gleefully discovering the joys of dating and dancing. While Carola struggled for an exciting and satisfying life, Teresa faced adolescence and young adulthood, increasingly burdened by Carola's dysfunction. Finally, as the family splintered between colleges, homes, stepfathers, and their mother's disintegrating mental health, Teresa drove Carola to a mental hospital--where at last the mother of five found some peace and order.Upon leaving the hospital, sadly Carola continued in a downward spiral: more men, a drug addiction, a toddler son's death, and finally her own accidental overdose death in 1974. Though Carola's unhappy life meant Teresa's was marked by hardship and tragedy, Teresa found redemption in writing her mother's story and discovering empathy for the woman continually harmed by her own bad choices. The bonds of sisterhood helped sustain her, and today the girls are still close, still savoring the good in a childhood pocked with pain. Teresa, now a counselor and mother of a daughter, was able to conclude, after visiting her mom's grave and asking her blessing on the book, I believe joy and sorry rest together, the two sides of love. I have repeatedly uncovered places of joy inside my own heart tucked within the folds of sorrow.  With enormous skill and sensitivity, Teresa deftly explores the history she shared with Carola and the relentless love of a child for her mother.

    Doctors predicted that she would never intellectually develop beyond the abilities of a small child. Although she made some progress after years of intensive behavioral and communication therapy, Carly remained largely unreachable. Then, at the age of ten, she had a breakthrough. While working with her devoted therapists Howie and Barb, Carly reached over to their laptop and typed in "HELP TEETH HURT," much to everyone's astonishment. This was the beginning of Carly's journey toward self-realization. Although Carly still struggles with all the symptoms of autism, which she describes with uncanny accuracy and detail, she now has regular, witty, and profound conversations on the computer with her family, her therapists, and the many thousands of people who follow her via her blog, Facebook, and Twitter. In Carly's Voice, her father, Arthur Fleischmann, blends Carly's own words with his story of getting to know his remarkable daughter. One of the first books to explore firsthand the challenges of living with autism, it brings readers inside a once-secret world and in the company of an inspiring young woman who has found her voice and her mission.

    But when Isaacson, a lifelong horseman, rode their neighbor's horse with Rowan, Rowan improved immeasurably. He was struck with a crazy idea: why not take Rowan to Mongolia, the one place in the world where horses and shamanic healing intersected? THE HORSE BOY is the dramatic and heartwarming story of that impossible adventure. In Mongolia, the family found undreamed of landscapes and people, unbearable setbacks, and advances beyond their wildest dreams. This is a deeply moving, truly one-of-a-kind story--of a family willing to go to the ends of the earth to help their son, and of a boy learning to connect with the world for the first time.

    It was thrilling, because it was an unthinkable act.After Kate Mayfield was born, she was taken directly to a funeral home. Her father was an undertaker, and for thirteen years the family resided in a place nearly synonymous with death. A place where the living and the dead entered their house like a vapor. The place where Kate would spend the entirety of her childhood. In a memoir that reads like a Harper Lee novel, Mayfield draws the reader into a world of Southern mystique and ghosts.Kate's father set up shop in a small town where he was one of two white morticians during the turbulent 1960s. Jubilee, Kentucky, was a segregated, god-fearing community where no one kept secrets, except the ones they were buried with. By opening a funeral home, Kate's father also opened the door to family feuds, fetishes, and victims of accidents, murder, and suicide. The family saw it all. They also saw the quiet ruin of Kate's father, who hid alcoholism and infidelity behind a cool, charismatic exterior. As Mayfield grows from trusting child to rebellious teen, she begins to find the enforced hush of the funeral home oppressive, and longs for the day she can escape the confines of her small town.In The Undertaker's Daughter, Kate has written a triumph of a memoir. This vivid and stranger-than-fiction true story ultimately teaches us how living in a house of death can prepare one for life.

    Dale was still a baby when his parents realised that something wasn't right. Worried, his mother Nuala took him to see several doctors, before finally hearing the word 'autism' for the first time in a specialist's office. Scared but determined that Dale should live a fulfilling life, Nuala describes her despairat her son's condition, her struggle to prevent Dale being excluded from a 'normal' education and her sense of hopeless isolation. Dale's autism was severe and violent and family life was a daily battleground. But the Gardner's lives were transformed when they welcomed a gorgeous Golden Retriever into the family. The special bond between Dale and his dog Henry helped them to produce the breakthrough in Dale they had long sought. From taking a bath to saying 'I love you', Henry helped introduce Dale to all the normal activities most parents take for granted, and set him on the road to being the charming and well-adjusted young man he is today. This is a heartrending and fascinating account of how one devoted and talented dog helped a little boy conquer his autism.

    Now they must empty and sell the beloved family home, which hasn't been de-cluttered in more than half a century. Twenty-three rooms bulge with history, antiques, and oxygen tanks. Plum remembers her loving but difficult parents who could not have been more different: the British father, a handsome, disciplined patriarch who nonetheless could not control his opinionated,extroverted Southern-belle wife who loved tennis and gin gimlets. The task consumes her, becoming more rewarding than she ever imagined. Items from childhood trigger memories of her eccentric family growing up in a small town on the shores of Lake Ontario in the 1950's and 60's. But unearthing new facts about her parents helps her reconcile those relationships with a more accepting perspective about who they were and what they valued.They Left Us Everything is a funny, touching memoir about the importance of preserving family history to make sense of the past and nurturing family bonds to safeguard the future.

    Marriage is simultaneously the biggest blessing and the greatest challenge two people can ever take on. It is the joy of knowing there is someone to share in your joys and sorrows, and the challenge of living with someone who thinks it's a good idea to hang a giant antelope head on your living room wall. In The Antelope in the Living Room, New York Times best-selling author and blogger Melanie Shankle does for marriage what Sparkly Green Earrings did for motherhood--makes us laugh out loud and smile through tears as she shares the holy and the hilarity of that magical and mysterious union called marriage.

    And here is the world after Mark was released from a mental hospital to find his family forever altered. At the late age of twenty-eight—and after nineteen rejections—Mark was accepted to Harvard Medical School, where he gained purpose, a life, and some control over his condition.The brilliantly evoked events of Mark Vonnegut’s life are at once perfectly unique and achingly relatable. There are the manic episodes, during which he felt burdened with saving the world, juxtaposed against the real-world responsibilities of running a pediatric practice. At times he felt that his parents’ lives would improve if only they had a few hundred more bucks in their bank account, while at other points his father’s fame merely heightened expectations that he be better, funnier (and crazier) than the average person.Ultimately a tribute to the small, daily, and positive parts of a life interrupted by bipolar disorder, Just Like Someone Without Mental Illness Only More So is a wise, unsentimental, and inspiring book that will resonate with generations of readers.