Operations on the brain carry grave risks. Every day, leading neurosurgeon Henry Marsh must make agonizing decisions, often in the face of great urgency and uncertainty.If you believe that brain surgery is a precise and exquisite craft, practiced by calm and detached doctors, this gripping, brutally honest account will make you think again. With astonishing compassion and candor, Marsh reveals the fierce joy of operating, the profoundly moving triumphs, the harrowing disasters, the haunting regrets, and the moments of black humor that characterize a brain surgeon's life.Do No Harm provides unforgettable insight into the countless human dramas that take place in a busy modern hospital. Above all, it is a lesson in the need for hope when faced with life's most difficult decisions.

    In The Ends of the World, Peter Brannen dives into deep time, exploring Earth’s past dead ends, and in the process, offers us a glimpse of our possible future.Many scientists now believe that the climate shifts of the twenty-first century have analogs in these five extinctions. Using the visible clues these devastations have left behind in the fossil record, The Ends of the World takes us inside “scenes of the crime,” from South Africa to the New York Palisades, to tell the story of each extinction. Brannen examines the fossil record—which is rife with creatures like dragonflies the size of sea gulls and guillotine-mouthed fish—and introduces us to the researchers on the front lines who, using the forensic tools of modern science, are piecing together what really happened at the crime scenes of the Earth’s biggest whodunits.Part road trip, part history, and part cautionary tale, The Ends of the World takes us on a tour of the ways that our planet has clawed itself back from the grave, and casts our future in a completely new light.

    Beginning with the study of DNA in Egyptian mummies in the early 1980s and culminating in the sequencing of the Neanderthal genome in 2010, Neanderthal Man describes the events, intrigues, failures, and triumphs of these scientifically rich years through the lens of the pioneer and inventor of the field of ancient DNA.We learn that Neanderthal genes offer a unique window into the lives of our hominin relatives and may hold the key to unlocking the mystery of why humans survived while Neanderthals went extinct. Drawing on genetic and fossil clues, Pääbo explores what is known about the origin of modern humans and their relationship to the Neanderthals and describes the fierce debate surrounding the nature of the two species’ interactions. His findings have not only redrawn our family tree, but recast the fundamentals of human history—the biological beginnings of fully modern Homo sapiens, the direct ancestors of all people alive today.A riveting story about a visionary researcher and the nature of scientific inquiry, Neanderthal Man offers rich insight into the fundamental question of who we are.

    The media seized hold of the story and, in the process, helped to launch one of the most devastating health scares ever. In the years to come Wakefield would be revealed as a profiteer in league with class-action lawyers, and he would eventually lose his medical license. Meanwhile, one study after another failed to find any link between childhood vaccines and autism. Yet the myth that vaccines somehow cause developmental disorders lives on. Despite the lack of corroborating evidence, it has been popularized by media personalities such as Oprah Winfrey and Jenny McCarthy and legitimized by journalists who claim that they are just being fair to “both sides” of an issue about which there is little debate. Meanwhile, millions of dollars have been diverted from potential breakthroughs in autism research; families have spent their savings on ineffective “miracle cures"; and declining vaccination rates have led to outbreaks of deadly illnesses like Hib, measles, and whooping cough. Most tragic of all is the increasing number of children dying from vaccine-preventable diseases. In The Panic Virus Seth Mnookin draws on interviews with parents, public-health advocates, scientists, and anti-vaccine activists to tackle a fundamental question: How do we decide what the truth is? The fascinating answer helps explain everything from the persistence of conspiracy theories about 9/11 to the appeal of talk-show hosts who demand that President Obama “prove” he was born in America. The Panic Virus is the ultimate cautionary tale for our time.

    The set includes thirty-one 30-minute MCAT practice exams with answers and explanations and more than 1,600 MCAT questions.

    Days later, the madman was dead and Denis was framed for murder. A riveting exposé of the fierce debates, deadly politics, and cutthroat rivalries behind the first transfusion experiments, Blood Work takes us from dissection rooms in palaces to the streets of Paris, providing an unforgettable portrait of an era that wrestled with the same questions about morality and experimentation that haunt medical science today.

    The new edition is thoroughly updated, including most notably a new chapter on innate immunity, a capstone chapter on immune responses in time and space, and many new focus boxes drawing attention to exciting clinical, evolutionary, or experimental connections that help bring the material to life.See what's in the LaunchPad

    Beginning with the above questions, she began informally researching every affliction that she encountered in humans to learn whether it happened with animals, too. And usually, it did: dinosaurs suffered from brain cancer, koalas can catch chlamydia, reindeer seek narcotic escape in hallucinogenic mushrooms, stallions self-mutilate, and gorillas experience clinical depression. Natterson-Horowitz and science writer Kathryn Bowers have dubbed this pan-species approach to medicine zoobiquity. Here, they present a revelatory understanding of what animals can teach us about the human body and mind, exploring how animal and human commonality can be used to diagnose, treat, and heal patients of all species.

    Conventional wisdom may be wrong. In this controversial book, the eminent biologist Paul W. Ewald offers some startling arguments:-Germs appear to be at the root of heart disease, Alzheimer’s, schizophrenia, many forms of cancer, and other chronic diseases.-The greatest threats to our health come not from sensational killers such as Ebola, West Nile virus, and super-virulent strains of influenza, but from agents that are already here causing long-term infections, which eventually lead to debilitation and death. -The medical establishment has largely ignored the evidence that implicates these germs, to the detriment of our public health.-New evolutionary theories are available, which explain how germs function and offer opportunities for controlling these modern plagues — if we are willing to listen to them.Plague Time is an eye-opening exploration of the revolutionary new understanding of disease that may set the course of medical research for the twenty-first century.

    The book brings together the latest in neuroscience research to present a new and proven approach to brain health and aging." “The most important book you’ll read this year.” The Neurogenesis Diet and Lifestyle brings together the latest in neuroscience research to present a new and proven view of brain health and aging. Only recently has it been discovered that the brain produces new brain cells throughout our entire lives, a process called neurogenesis. The rate at which we form new brain cells has a profound influence upon every aspect of our life. When the rate of neurogenesis is low, we see cognitive deficits and memory problems, anxiety and stress, depression, and lowered immunity. Life is difficult. With high rates of neurogenesis we see the opposite: enhanced cognitive abilities, rapid learning, emotional resilience, protection from anxiety, stress and depression, heightened immunity and robust health. We flourish. Life is wonderful. Given the neurotoxic norms of society, it’s almost universally true that your brain is working far below its capacity. It is deteriorating much faster than it needs to. What good is living longer if your brain can’t go the distance? Recent discoveries in the emerging field of neurogenesis reveal the secrets to radically improve your brain’s health. You can operate at a higher level than you ever dreamed possible – at any age! ”A revolutionary paradigm shift in brain health and brain aging." This scientifically validated, 4-point program of diet and lifestyle will: • Improve your memory and brain power • Inoculate you against stress and depression • Prevent or delay cognitive decline, dementia and Alzheimer’s • Enrich your relationships and sex life • Help you connect with your loving center of peace This book presents the latest neuroscience discoveries to increase brain power, enhance memory, increase brain fitness by seeing what kinds of brain exercises actually work, and build a better brain. It contains dietary recommendations for brain food, brain vitamins, brain supplements, memory vitamins and memory supplements. “This is the best book to give anyone over 50!” This book also spells out the symptoms of dementia, the stages of dementia, signs of cognitive decline and stages of Alzheimer’s. The plan presented in The Neurogenesis Diet and Lifestyle will help to ward off cognitive decline and avoid dementia stages. This lifestyle is the only lifestyle for which there is scientific evidence supporting it, based on a late 2014 research study by the Buck Foundation. The Neurogenesis Diet and Lifestyle is aimed at improving how your brain functions. Your rate of neurogenesis may be the most important factor in your brain health. And increasing your rate of neurogenesis by three to five times can result in powerfully improved memory, learning, cognitive enhancement, as well as improved immunity and protection against stress and depression. You can live and perform well beyond where you are now. For more information, please visit: NeurogenesisDiet.

    What at first seemed like a case of food poisoning quickly turned critical, and by the time Tom had been transferred via emergency medevac to the world-class medical center at UC San Diego, where both he and Steffanie worked, blood work revealed why modern medicine was failing: Tom was fighting one of the most dangerous, antibiotic-resistant bacteria in the world.Frantic, Steffanie combed through research old and new and came across phage therapy: the idea that the right virus, aka "the perfect predator," can kill even the most lethal bacteria. Phage treatment had fallen out of favor almost 100 years ago, after antibiotic use went mainstream. Now, with time running out, Steffanie appealed to phage researchers all over the world for help. She found allies at the FDA, researchers from Texas A&M, and a clandestine Navy biomedical center -- and together they resurrected a forgotten cure.

    Darwin wondered why these birds were confined to remote islands at the tip of South America, sensing a larger story, but he set this mystery aside and never returned to it. Almost two hundred years later, Jonathan Meiburg takes up this chase. He takes us through South America, from the fog-bound coasts of Tierra del Fuego to the tropical forests of Guyana, in search of these birds: striated caracaras, which still exist, though they're very rare. He reveals the wild, fascinating story of their history, origins, and possible futures. And along the way, he draws us into the life and work of William Henry Hudson, the Victorian writer and naturalist who championed caracaras as an unsung wonder of the natural world, and to falconry parks in the English countryside, where captive caracaras perform incredible feats of memory and problem-solving. A Most Remarkable Creature is a hybrid of science writing, travelogue, and biography, as generous and accessible as it is sophisticated, and absolutely riveting.

    Mammoths, camels, and lions walked the ground that has become Wilshire Boulevard in Los Angeles and foraged on the marsh land now buried beneath Chicago's streets. Then, just as the first humans reached the Americas, these Ice Age giants vanished forever. In Once and Future Giants, science writer Sharon Levy digs through the evidence surrounding Pleistocene large animal ("megafauna") extinction events worldwide, showing that understanding this history--and our part in it--is crucial for protecting the elephants, polar bears, and other great creatures at risk today. These surviving relatives of the Ice Age beasts now face an intensified replay of that great die-off, as our species usurps the planet's last wild places while driving a warming trend more extreme than any in mammalian history. Inspired by a passion for the lost Pleistocene giants, some scientists advocate bringing elephants and cheetahs to the Great Plains as stand-ins for their extinct native brethren. By reintroducing big browsers and carnivores to North America, they argue, we could rescue some of the planet's most endangered animals while restoring healthy prairie ecosystems. Critics, including biologists enmeshed in the struggle to restore native species like the gray wolf and the bison, see the proposal as a dangerous distraction from more realistic and legitimate conservation efforts. Deftly navigating competing theories and emerging evidence, Once and Future Giants examines the extent of human influence on megafauna extinctions past and present, and explores innovative conservation efforts around the globe. The key to modern-day conservation, Levy suggests, may lie fossilized right under our feet.

    Humans: from the beginning will appeal to anybody who reads about these discoveries, is intrigued by them, and would like to know more about prehistory. Now brought fully up to date for 2015, Humans: from the beginning is a single-volume guide to the human past. Drawing upon expert literature and the latest multi-disciplinary research, this rigorous but accessible book traces the whole of the human story from the first apes to the first cities. The end product of five years of research, it has also been planned from the ground up to take advantage of the eBook format and ease access to visual matter, references and glossary items. Humans: from the beginning is written for the non-specialist, but it is sufficiently comprehensive in scope, rigorous in content, and well-referenced to serve as an ideal ‘one-stop’ text not only for undergraduate students of relevant disciplines, but also to postgraduates, researchers and other academics seeking to broaden their knowledge. This 32-chapter work presents an even-handed coverage of topics including: • How climate change has long played a pivotal role in our affairs and those of our ancestors. • How humans evolved from apes at a time when the apes were facing extinction. • Why the last common ancestor of humans and chimpanzees (our closest living relatives) might have been more like a human than a chimpanzee. • A possible Asian rather than African origin for the earliest humans. • Why the Neanderthals were not the dimwits of popular imagination. • How language and modern human behaviour evolved: an examination of theories including those of Robin Dunbar, Steven Mithen and Derek Bickerton. • How the small group of modern humans that eventually colonised the whole of the non-African world might have started from Arabia rather than Africa. • David Lewis-Williams’ theory that the cave art of Ice Age Europe was linked to a shamanistic belief system that might be rooted in the very architecture of the human brain. • Why the Neolithic transition from hunter-gathering to agriculture was a lengthy process, with many down sides. • Colin Renfrew’s still-controversial theory that the spread of farming communities in Neolithic times was responsible for the languages now spoken in many parts of the world. • How an ‘Urban Revolution’ replaced egalitarian farming communities with socially-stratified kingdoms and city-states in just a few millennia. • How the complex, technological societies of today have much in common with not only the earliest states but much earlier primate societies.

    He argues that humans have evolved a universal moral instinct, unconsciously propelling us to deliver judgments of right and wrong independent of gender, education, and religion. Experience tunes up our moral actions, guiding what we do as opposed to how we deliver our moral verdicts.For hundreds of years, scholars have argued that moral judgments arise from rational and voluntary deliberations about what ought to be. The common belief today is that we reach moral decisions by consciously reasoning from principled explanations of what society determines is right or wrong. This perspective has generated the further belief that our moral psychology is founded entirely on experience and education, developing slowly and subject to considerable variation across cultures. In his groundbreaking book, Hauser shows that this dominant view is illusory.Combining his own cutting-edge research with findings in cognitive psychology, linguistics, neuroscience, evolutionary biology, economics, and anthropology, he examines the implications of his theory for issues of bioethics, religion, law, and our everyday lives.