It enabled us to migrate out of Africa and to spread as far as Alaska and Australia. Every day, we put one foot in front of the other―yet how many of us know how we do that, or appreciate the advantages it gives us?Neuroscientist Shane O’Mara invites us to marvel at the benefits walking confers on our bodies and brains. From walking’s evolutionary origins, traced back millions of years to life forms on the ocean floor, to new findings from cutting- edge research, he reveals how the brain and nervous system give us the ability to balance, weave through a crowded city, and run our “inner GPS” system. Walking, in turn, spurs our imaginations and boosts our moods. In Praise of Walking illuminates the joys, health benefits, and mechanics of walking―and reminds us to get out of our chairs and discover a happier, healthier, more creative self.

    With more than one in every five people over the age of fourteen addicted, drug abuse has been called the most formidable health problem worldwide. If we are not victims ourselves, we all know someone struggling with the merciless compulsion to alter their experience by changing how their brain functions.Drawing on years of research--as well as personal experience as a recovered addict--researcher and professor Judy Grisel has reached a fundamental conclusion: for the addict, there will never be enough drugs. The brain's capacity to learn and adapt is seemingly infinite, allowing it to counteract any regular disruption, including that caused by drugs. What begins as a normal state punctuated by periods of being high transforms over time into a state of desperate craving that is only temporarily subdued by a fix, explaining why addicts are unable to live either with or without their drug. One by one, Grisel shows how different drugs act on the brain, the kind of experiential effects they generate, and the specific reasons why each is so hard to kick.Grisel's insights lead to a better understanding of the brain's critical contributions to addictive behavior, and will help inform a more rational, coherent, and compassionate response to the epidemic in our homes and communities.

    Yet these creatures are our cousins. As fellow members of the animal kingdom—the Metazoa—they can teach us much about the evolutionary origins of not only our bodies, but also our minds.In his acclaimed 2016 book, Other Minds, the philosopher and scuba diver Peter Godfrey-Smith explored the mind of the octopus—the closest thing to an intelligent alien on Earth. In Metazoa, Godfrey-Smith expands his inquiry to animals at large, investigating the evolution of subjective experience with the assistance of far-flung species. As he delves into what it feels like to perceive and interact with the world as other life-forms do, Godfrey-Smith shows that the appearance of the animal body well over half a billion years ago was a profound innovation that set life upon a new path. In accessible, riveting prose, he charts the ways that subsequent evolutionary developments—eyes that track, for example, and bodies that move through and manipulate the environment—shaped the subjective lives of animals. Following the evolutionary paths of a glass sponge, soft coral, banded shrimp, octopus, and fish, then moving onto land and the world of insects, birds, and primates like ourselves, Metazoa gathers their stories together in a way that bridges the gap between mind and matter, addressing one of the most vexing philosophical problems: that of consciousness.Combining vivid animal encounters with philosophical reflections and the latest news from biology, Metazoa reveals that even in our high-tech, AI-driven times, there is no understanding our minds without understanding nerves, muscles, and active bodies. The story that results is as rich and vibrant as life itself.

    For decades, these questions have lived exclusively in the realm of science fiction, but as Kevin Davies powerfully reveals in his new book, this is all about to change.Engrossing and page-turning, Editing Humanity takes readers inside the fascinating world of a new gene editing technology called CRISPR, a high-powered genetic toolkit that enables scientists to not only engineer but to edit the DNA of any organism down to the individual building blocks of the genetic code.Davies introduces readers to arguably the most profound scientific breakthrough of our time. He tracks the scientists on the front lines of its research to the patients whose powerful stories bring the narrative movingly to human scale.Though the birth of the “CRISPR babies” in China made international news, there is much more to the story of CRISPR than headlines seemingly ripped from science fiction. In Editing Humanity, Davies sheds light on the implications that this new technology can have on our everyday lives and in the lives of generations to come.

    Here he tackles all the "big questions," including the biggest of them all: Why does the universe seem so well adapted for life? In his characteristically clear and elegant style, Davies shows how recent scientific discoveries point to a perplexing fact: many different aspects of the cosmos, from the properties of the humble carbon atom to the speed of light, seem tailor-made to produce life. A radical new theory says it's because our universe is just one of an infinite number of universes, each one slightly different. Our universe is bio-friendly by accident -- we just happened to win the cosmic jackpot. While this "multiverse" theory is compelling, it has bizarre implications, such as the existence of infinite copies of each of us and Matrix-like simulated universes. And it still leaves a lot unexplained. Davies believes there's a more satisfying solution to the problem of existence: the observations we make today could help shape the nature of reality in the remote past. If this is true, then life -- and, ultimately, consciousness -- aren't just incidental byproducts of nature, but central players in the evolution of the universe. Whether he's elucidating dark matter or dark energy, M-theory or the multiverse, Davies brings the leading edge of science into sharp focus, provoking us to think about the cosmos and our place within it in new and thrilling ways.

    The culprit--so necessary and yet the source of such upheaval--is the X chromosome, and this is its story. An enlightening and entertaining tour of the cultural and natural history of this intriguing member of the genome, "The X in Sex" traces the journey toward our current understanding of the nature of X. From its chance discovery in the nineteenth century to the promise and implications of ongoing research, David Bainbridge shows how the X evolved and where it and its counterpart Y are going, how it helps assign developing human babies their sex--and maybe even their sexuality--and how it affects our lives in infinitely complex and subtle ways. X offers cures for disease, challenges our cultural, ethical, and scientific assumptions about maleness and femaleness, and has even reshaped our views of human evolution and human nature.

    Now, he presents his conclusions in this brave and pioneering book. Axe argues that the key to understanding our origin is the “design intuition”—the innate belief held by all humans that tasks we would need knowledge to accomplish can only be accomplished by someone who has that knowledge. For the ingenious task of inventing life, this knower can only be God.Starting with the hallowed halls of academic science, Axe dismantles the widespread belief that Darwin’s theory of evolution is indisputably true, showing instead that a gaping hole has been at its center from the beginning. He then explains in plain English the science that proves our design intuition scientifically valid. Lastly, he uses everyday experience to empower ordinary people to defend their design intuition, giving them the confidence and courage to explain why it has to be true and the vision to imagine what biology will become when people stand up for this truth.Armed with that confidence, readers will affirm what once seemed obvious to all of us—that living creatures, from single-celled cyanobacteria to orca whales and human beings, are brilliantly conceived, utterly beyond the reach of accident.Our intuition was right all along.

    Moreover, present-day research on electricity and ion channels has created one of the most exciting fields in science, shedding light on conditions ranging from diabetes and allergies to cystic fibrosis, migraines, and male infertility. With inimitable wit and a clear, fresh voice, award-winning researcher Frances Ashcroft weaves together compelling real-life stories with the latest scientific findings, giving us a spectacular account of the body electric.

    As evidenced in the record, whales evolved from herbivorous forest-dwelling ancestors that resembled tiny deer to carnivorous monsters stalking lakes and rivers and to serpentlike denizens of the coast. Thewissen reports on his discoveries in the wilds of India and Pakistan, weaving a narrative that reveals the day-to-day adventures of fossil collection, enriching it with local flavors from South Asian culture and society. The reader senses the excitement of the digs as well as the rigors faced by scientific researchers, for whom each new insight gives rise to even more questions, and for whom at times the logistics of just staying alive may trump all science. In his search for an understanding of how modern whales live their lives, Thewissen also journeys to Japan and Alaska to study whales and wild dolphins. He finds answers to his questions about fossils by studying the anatomy of otters and porpoises and examining whale embryos under the microscope. In the book's final chapter, Thewissen argues for approaching whale evolution with the most powerful tools we have and for combining all the fields of science in pursuit of knowledge.

    And yet, in our popular conception it exists largely as a footnote to World War I.In Pale Rider, Laura Spinney recounts the story of an overlooked pandemic, tracing it from Alaska to Brazil, from Persia to Spain, and from South Africa to Odessa. She shows how the pandemic was shaped by the interaction of a virus and the humans it encountered; and how this devastating natural experiment put both the ingenuity and the vulnerability of humans to the test.Laura Spinney writes that the Spanish flu was as significant – if not more so – as two world wars in shaping the modern world; in disrupting, and often permanently altering, global politics, race relations, family structures, and thinking across medicine, religion and the arts.

    Just ask biotechnologist Matti Leisola. It all started when a student loaned the Finnish scientist a book criticizing evolutionary theory. Leisola reacted angrily, and set out to defend evolution, but found his efforts raised more questions than they answered. He soon morphed into a full-on Darwin skeptic, even as he was on his way to becoming a leading bio-engineer.Heretic is the story of Leisola's adventures making waves-and many friends and enemies-at major research labs and universities across Europe. Tracing his investigative path, the book draws on Leisola's expertise in molecular biology to show how the evidence points more strongly than ever to the original biotechnologist-a designing intelligence whose skill and reach dwarf those of even our finest bioengineers, and leave blind evolution in the dust.Endorsements "Award-winning Finnish biotechnologist Matti Leisola has written a fascinating account of what happens when a scientist follows the evidence wherever it leads. Leisola's account of how he succeeded should inspire up-and-coming scientists who face the same challenge." Biologist Jonathan Wells, PhD, author of Icons of Evolution and Zombie Science "Scientists, like all other intellectuals, have ideas about what constitutes and what does not constitute reality. However, they are often not aware-and sometimes not ready to admit-that such ideas represent the principles of their philosophy. Leisola and Witt's Heretic is a unique first-hand account of the life-long adventures of a scientist who dared to challenge philosophical principles of colleague scientists. In my opinion, the outcome shows that to many scientists their philosophy is dearer than their science." Biochemist and inventor Branko Kozulic, PhD "This book is an exciting story about how a scientist's relentless search for truth makes him a heretic in the eyes of a cultural community more concerned about prestige than principle." Tapio Puolimatka, PhD and EdD, University of Jyvaskyla, Finland "This book is a personal, strong, and motivated plea for intelligent design (ID) and 'swims against the current' of Darwinian evolution, now generally accepted in scientific circles and society. I personally do not endorse ID, but I am a good friend of the author, whom I also highly respect as a scientist active in academia and in the biotech industry over so many years. Heretic inspires readers to think critically and to open up a civilized discussion on neo-Darwinism versus ID. It covers the science and philosophical parts adequately; it is accessible to a large readership; and statements are underpinned by relevant research and literature data. Its value lies in the author's lifelong engagement and personal crusade to stimulate the public debate among scientists as well as laymen over Darwinism (chance/random mutation and natural selection) versus ID, a vision that Leisola strongly advocates." Dr. Erick J. Vandamme, Emeritus Professor of Bioscience Engineering, Ghent University, Belgium "Matti Leisola has written the exciting story of almost the entire spectrum of aberrant motives, absurd fears, and unreasonable reactions to intelligent design (ID) by evolutionary scientists, clergymen, and church institutions alike, notably during his career as a scientist over the last some forty years. I would add a word on the fears of so many critics that accepting ID also means accepting the dogmata of some 1700 years of church history. ID is thoroughly neutral concerning such topics. So, the reader is invited to carefully check the historical and, what is more, the enormous wealth of scientific data Matti Leisola has presented in the present book: Test them carefully with an open mind and form your own independent opinion!" Dr. Wolf-Ekkehard Lonnig, geneticist, Cologne,

    They distill more than 20 years of research and first-hand accounts from the most biodiverse ecosystems on Earth into straightforward principles and guidance for confronting our culture of hyper-novelty.For evolutionary biologists Heather Heying and Bret Weinstein, the cause of our woes is clear: the modern world is out of sync with our ancient brains and bodies. We evolved to live in clans, but today most people don't even know their neighbors' names. Differences between the sexes once served a necessary evolutionary purpose, but today many dismiss the concept of biological sex as offensive. The cognitive dissonance spawned by trying to live in a society we're not built for is killing us.

    Best-selling paleontology author Donald R. Prothero describes twenty-five famous, beautifully preserved fossils in a gripping scientific history of life on Earth. Recounting the adventures behind the discovery of these objects and fully interpreting their significance within the larger fossil record, Prothero creates a riveting history of life on our planet.The twenty-five fossils portrayed in this book catch animals in their evolutionary splendor as they transition from one kind of organism to another. We witness extinct plants and animals of microscopic and immense size and thrilling diversity. We learn about fantastic land and sea creatures that have no match in nature today. Along the way, we encounter such fascinating fossils as the earliest trilobite, Olenellus; the giant shark Carcharocles; the "fishibian" Tiktaalik; the "Frogamander" and the "Turtle on the Half-Shell"; enormous marine reptiles and the biggest dinosaurs known; the first bird, Archaeopteryx; the walking whale Ambulocetus; the gigantic hornless rhinoceros Paraceratherium, the largest land mammal that ever lived; and the Australopithecus nicknamed "Lucy," the oldest human skeleton. We meet the scientists and adventurers who pioneered paleontology and learn about the larger intellectual and social contexts in which their discoveries were made. Finally, we find out where to see these splendid fossils in the world's great museums.Ideal for all who love prehistoric landscapes and delight in the history of science, this book makes a treasured addition to any bookshelf, stoking curiosity in the evolution of life on Earth.

    With numerous black-and-white images and eight pages of color plates, The Lives of Ants provides a state-of-the-art look at what we now know about these fascinating creatures, portraying a world that is rich and full of surprises, one which, even after decades of observation, is still full of unsolved mysteries.The authors illuminate the world of the ant, shedding light on such topics as the ant's impressive abilities in direction finding and quite amazing ingenuity when it comes to building their nests, finding supplies, or exploiting other members of the animal kingdom. They show, too, that they are capable of aggression and violence, which can disturb the apparent peace of their colonies and embroil them in fratricidal or matricidal strife. Even their sexual arrangements are at times quite strange. In this area, as in many others, they display marked originality. Readers also discover that ants are walking bundles of secretory glands (they have about forty of them), which enable them to emit between ten and twenty different pheromones, each of which has its own "meaning." Some are produced by workers for recruiting their sisters or for alerting them to danger. Others are used for marking territory, for identifying members of their colony or conversely for detecting foreigners, and for indicating the location of food. In addition, ants can also emit sound signals, made of a high-pitched squeak, and they can even dance, though not as intricately or as well as bees.The Lives of Ants combines natural history with molecular biology, genetics, and even the latest developments in robotics, to explore the remarkable societies of ants, revealing the secrets of their mysterious lives.

    Gonzalez-Crussi, from the Introduction An international bestseller, translated into eighteen languages, Paul de Kruif’s classic account of the first scientists to see and learn about the microscopic world continues to fascinate new readers. This is a timeless dramatization of the scientists, bacteriologists, doctors, and medical technicians who discovered the microbes and invented the vaccines to counter them. De Kruif writes about how seemingly simple but really fundamental discovers of science—for instance, how a microbe was first viewed in a clear drop of rain water, and when, for the first time, Louis Pasteur discovered that a simple vaccine could save a man from the ravages of rabies by attacking the microbes that cause it.