But in the inevitable condition of aging and death, the goals of medicine seem too frequently to run counter to the interest of the human spirit. Nursing homes, preoccupied with safety, pin patients into railed beds and wheelchairs. Hospitals isolate the dying, checking for vital signs long after the goals of cure have become moot. Doctors, committed to extending life, continue to carry out devastating procedures that in the end extend suffering.Gawande, a practicing surgeon, addresses his profession's ultimate limitation, arguing that quality of life is the desired goal for patients and families. Gawande offers examples of freer, more socially fulfilling models for assisting the infirm and dependent elderly, and he explores the varieties of hospice care to demonstrate that a person's last weeks or months may be rich and dignified.

    Because of this balance, "Microbiology" is appropriate for microbiology majors and mixed majors courses. The new authors have focused on readability, artwork, and the integration of several key themes (including evolution, ecology and diversity) throughout the text, making an already superior text even better.

    In How to Clone a Mammoth, Beth Shapiro, evolutionary biologist and pioneer in "ancient DNA" research, walks readers through the astonishing and controversial process of de-extinction. From deciding which species should be restored, to sequencing their genomes, to anticipating how revived populations might be overseen in the wild, Shapiro vividly explores the extraordinary cutting-edge science that is being used--today--to resurrect the past. Journeying to far-flung Siberian locales in search of ice age bones and delving into her own research--as well as those of fellow experts such as Svante Paabo, George Church, and Craig Venter--Shapiro considers de-extinction's practical benefits and ethical challenges. Would de-extinction change the way we live? Is this really cloning? What are the costs and risks? And what is the ultimate goal?Using DNA collected from remains as a genetic blueprint, scientists aim to engineer extinct traits--traits that evolved by natural selection over thousands of years--into living organisms. But rather than viewing de-extinction as a way to restore one particular species, Shapiro argues that the overarching goal should be the revitalization and stabilization of contemporary ecosystems. For example, elephants with genes modified to express mammoth traits could expand into the Arctic, re-establishing lost productivity to the tundra ecosystem.Looking at the very real and compelling science behind an idea once seen as science fiction, How to Clone a Mammoth demonstrates how de-extinction will redefine conservation's future.

    If you could bring back to life a person or animal, what would you choose? Pilcher highlights her own choices from eras gone, including the King of the Dinosaurs, Tyrannosaurus rex, and the King of Rock 'n' Roll, Elvis Presley.From dinosaurs to dodos and Neanderthals, BRING BACK THE KING reveals how the burgeoning field of DNA science is being used to help resurrect individual animals (did your beloved Fido die before siring offspring?) and entire species from their stony graves. Pilcher describes current initiatives and future plans to restore deceased animals, and uses both science and willful irreverence to assess the ramifications of how these genetic Lazaruses might fare in their brave new world. Could a pet dinosaur be trained to roll over? Would Neanderthals enjoy opera? Could a returning dodo seek vengeance upon humanity?Blending the very latest de-extinction technology with cloning, and hard-core popular science with levity, BRING BACK THE KING will generate a lot of thoughtful discussion and a chuckle or two.

    But, despite appearances, these are not dogs—they are foxes. They are the result of the most astonishing experiment in breeding ever undertaken—imagine speeding up thousands of years of evolution into a few decades. In 1959, biologists Dmitri Belyaev and Lyudmila Trut set out to do just that, by starting with a few dozen silver foxes from fox farms in the USSR and attempting to recreate the evolution of wolves into dogs in real time in order to witness the process of domestication. This is the extraordinary, untold story of this remarkable undertaking. Most accounts of the natural evolution of wolves place it over a span of about 15,000 years, but within a decade, Belyaev and Trut’s fox breeding experiments had resulted in puppy-like foxes with floppy ears, piebald spots, and curly tails. Along with these physical changes came genetic and behavioral changes, as well. The foxes were bred using selection criteria for tameness, and with each generation, they became increasingly interested in human companionship. Trut has been there the whole time, and has been the lead scientist on this work since Belyaev’s death in 1985, and with Lee Dugatkin, biologist and science writer, she tells the story of the adventure, science, politics, and love behind it all.  In How to Tame a Fox, Dugatkin and Trut take us inside this path-breaking experiment in the midst of the brutal winters of Siberia to reveal how scientific history is made and continues to be made today. To date, fifty-six generations of foxes have been domesticated, and we continue to learn significant lessons from them about the genetic and behavioral evolution of domesticated animals. How to Tame a Fox offers an incredible tale of scientists at work, while also celebrating the deep attachments that have brought humans and animals together throughout time.

    Ecosystem: Structure and Function Biogeochemical Cycles, Aquatic Ecosystems: Freshwater Communities, Estuaries and Marine Communities Terrestrial Ecosystems Pollution Ecology and Human Welfare Wild Life Management Biogeography, Adaptations Indices

    It is a waste product and a commodity pricier than oil. It can save lives and transmit deadly infections. Each one of us has roughly nine pints of it, yet many don’t even know their own blood type. And for all its ubiquity, the few tablespoons of blood discharged by 800 million women are still regarded as taboo; menstruation is perhaps the single most demonized biological event.Rose George, author of The Big Necessity, is renowned for her intrepid work on topics that are invisible but vitally important. In Nine Pints, she takes us from ancient practices of bloodletting to modern “hemovigilance” teams that track blood-borne diseases. She introduces Janet Vaughan, who set up the world’s first system of mass blood donation during the Blitz, and Arunachalam Muruganantham, known as “Menstrual Man” for his work on sanitary pads for developing countries. She probes the lucrative business of plasma transfusions, in which the U.S. is known as the “OPEC of plasma.” And she looks to the future, as researchers seek to bring synthetic blood to a hospital near you.Spanning science and politics, stories and global epidemics, Nine Pints reveals our life's blood in an entirely new light.

    In the mid-1970s, scientists began using DNA sequences to reexamine the history of all life. Perhaps the most startling discovery to come out of this new field—the study of life’s diversity and relatedness at the molecular level—is horizontal gene transfer (HGT), or the movement of genes across species lines. It turns out that HGT has been widespread and important. For instance, we now know that roughly eight percent of the human genome arrived not through traditional inheritance from directly ancestral forms, but sideways by viral infection—a type of HGT.David Quammen chronicles these discoveries through the lives of the researchers who made them—such as Carl Woese, the most important little-known biologist of the twentieth century; Lynn Margulis, the notorious maverick whose wild ideas about “mosaic” creatures proved to be true; and Tsutomu Wantanabe, who discovered that the scourge of antibiotic-resistant bacteria is a direct result of horizontal gene transfer, bringing the deep study of genome histories to bear on a global crisis in public health.

    These “psychosurgeons,” as they called themselves, occupied a gray zone between medical research and medical practice, and ended up subjecting untold numbers of people to the types of surgical experiments once limited to chimpanzees.The most important test subject to emerge from this largely untold chapter in American history was a twenty-seven-year-old factory worker named Henry Molaison. In 1953, Henry—who suffered from severe epilepsy—received a radical new version of the lobotomy, one that targeted the most mysterious structures in the brain. The operation failed to eliminate Henry’s seizures, but it did have an unintended effect: Henry left the operating room profoundly amnesic, unable to create new long-term memories. Over the next sixty years, Patient H.M., as Henry was known, became the most studied individual in the history of neuroscience, a human guinea pig who would teach us much of what we know about memory today.Luke Dittrich uses the case of Patient H.M. as a starting point for a kaleidoscopic journey, one that moves from the first recorded brain surgeries in ancient Egypt to the cutting-edge laboratories of MIT. He takes readers inside the old asylums and operating theaters where psychosurgeons conducted their human experiments, and behind the scenes of a bitter custody battle over the ownership of the most important brain in the world. Throughout, Dittrich delves into the enduring mysteries of the mind while exposing troubling stories of just how far we’ve gone in our pursuit of knowledge. It is also, at times, a deeply personal journey. Dittrich’s grandfather was the brilliant, morally complex surgeon who operated on Molaison—and thousands of other patients. The author’s investigation into the dark roots of modern memory science ultimately forces him to confront unsettling secrets in his own family history, and to reveal the tragedy that fueled his grandfather’s relentless experimentation—experimentation that would revolutionize our understanding of ourselves.Patient H.M. combines the best of biography, memoir, and science journalism to create a haunting, endlessly fascinating story, one that reveals the wondrous and devastating things that can happen when hubris, ambition, and human imperfection collide.

    We see our infant universe as it rapidly expands, formed by black holes belonging to another universe. He uses a cinematic style to show every step, with imagery taken from popular culture, archaeology, science, film, and art sources, and to take use through the formation of our solar system and the earth itself, charting the long course of biological evolution.Alpha is the first in a trilogy covering the world and mankind's evolution. Alpha is the starting point of investigating the pre-history of Earth, from just a speck in the sky to the birth of life that we cherish so much today. It is the 'greatest story in the world'

    Science writer and biologist Hanne Strager brings Darwin to life while offering the essential elements of evolution and how they affect us today.Much has been written on Darwin's life, his groundbreaking work, and the influence he has had on modern scientific thought and advancements, but most books assume a certain level of scientific knowledge. A Modest Genius changes that, offering an accessible, easy-to-understand discussion of Darwin's work.Readers follow Darwin from his early years through his travels. Hanne Strager explains how Darwin assembled the pieces of a fascinating puzzle while also describing the fundamental principles of evolution.Darwin's theory, by necessity, was incomplete when he proposed it. He lacked modern knowledge of the fossil record, DNA, and genetics. Strager explains how advances in these and other scientific areas expanded on Darwin's original work. She also discusses the ongoing conflict between religion and evolution, including the famous Scopes Monkey Trial and the battle Darwin himself fought between faith and intellect.Bold, exciting, and easily understood, A Modest Genius offers an opportunity to understand one of the greatest scientific breakthroughs of the modern age.

    Why are a quarter of a billion sperm cells needed to fertilize one egg? Are women really fertile for only a few days each month? How long should women breast-feed? In How We Do It, primatologist Robert Martin draws on forty years of research to locate the origins of everything from sex cells to baby care—and to reveal what’s really �natural” when it comes to making and raising babies. He acknowledges that although it’s not realistic to reproduce like our ancestors did, there are surprising consequences to behavior we take for granted, such as bottle feeding, cesarean sections, and in vitro fertilization. How We Do It shows that once we understand our evolutionary past, we can consider what worked, what didn’t, and what it all means for the future of our species.

    Now, faced with the threat of nuclear weapons and the effects of climate change, it seems our innate tendencies for violence and invention have led us to a crucial fork in our road. Where did these traits come from? Are they part of our species immutable destiny? Or is there hope for our species’ future if we change? With fascinating facts and his unparalleled readability, Diamond intended his book to improve the world that today’s young people will inherit. Triangle Square’s The Third Chimpanzee for Young People is a book for future generation and the future they’ll help build.

    And sugar is at the root of these, and other, critical society-wide, health-related problems. With his signature command of both science and straight talk, Gary Taubes delves into Americans' history with sugar: its uses as a preservative, as an additive in cigarettes, the contemporary overuse of high-fructose corn syrup. He explains what research has shown about our addiction to sweets. He clarifies the arguments against sugar, corrects misconceptions about the relationship between sugar and weight loss; and provides the perspective necessary to make informed decisions about sugar as individuals and as a society.

    In Dark Banquet, zoologist Bill Schutt takes readers on an entertaining voyage into the world of some of nature’s strangest creatures—the sanguivores. Using a sharp eye and mordant wit, Schutt makes a remarkably persuasive case that vampire bats, leeches, ticks, bed bugs, and other vampires are as deserving of our curiosity as warmer and fuzzier species are—and that many of them are even ­worthy of conservation.Schutt takes us from rural Trinidad to the jungles of Brazil to learn about some of the most reviled, misunderstood, and marvelously evolved animals on our planet: vampire bats. Only recently has fact begun to disentangle itself from fiction concerning these remarkable animals, and Schutt delves into the myths and misconceptions surrounding them. Examining the substance that sustains nature’s vampires, Schutt reveals just how little we actually knew about blood until well into the twentieth century. We revisit George Washington on his deathbed to learn how ideas about blood and the supposedly therapeutic value of bloodletting, first devised by the ancient Egyptians and Greeks, survived into relatively modern times. Schutt also tracks the history of medicinal leech use. Once employed by the tens of millions to drain perceived excesses of blood, today the market for these ancient creatures is booming once again—but for very different reasons.Among the other blood feeders we meet in these pages are bed bugs, or “ninja insects,” which are making a creepy resurgence in posh hotels and well-kept homes near you. In addition, Dark Banquet details our dangerous and sometimes deadly encounters with ticks, chiggers, and mites (the ­latter implicated in Colony Collapse Disorder—currently devastating honey bees worldwide). Then there are the truly weird—vampire finches. And if you thought piranha were scary, some people believe that the candiru (or willy fish) is the best reason to avoid swimming in the Amazon.Enlightening, alarming, and appealing to our delight in the bizarre, Dark Banquet peers into a part of the natural world to which we are, through our blood, inextricably linked.From the Hardcover edition.