It is a waste product and a commodity pricier than oil. It can save lives and transmit deadly infections. Each one of us has roughly nine pints of it, yet many don’t even know their own blood type. And for all its ubiquity, the few tablespoons of blood discharged by 800 million women are still regarded as taboo; menstruation is perhaps the single most demonized biological event.Rose George, author of The Big Necessity, is renowned for her intrepid work on topics that are invisible but vitally important. In Nine Pints, she takes us from ancient practices of bloodletting to modern “hemovigilance” teams that track blood-borne diseases. She introduces Janet Vaughan, who set up the world’s first system of mass blood donation during the Blitz, and Arunachalam Muruganantham, known as “Menstrual Man” for his work on sanitary pads for developing countries. She probes the lucrative business of plasma transfusions, in which the U.S. is known as the “OPEC of plasma.” And she looks to the future, as researchers seek to bring synthetic blood to a hospital near you.Spanning science and politics, stories and global epidemics, Nine Pints reveals our life's blood in an entirely new light.

    For centuries, royal families have feared the gut-roiling, vomit-inducing agony of a little something added to their food or wine by an enemy. To avoid poison, they depended on tasters, unicorn horns, and antidotes tested on condemned prisoners. Servants licked the royal family’s spoons, tried on their underpants and tested their chamber pots.Ironically, royals terrified of poison were unknowingly poisoning themselves daily with their cosmetics, medications, and filthy living conditions. Women wore makeup made with mercury and lead. Men rubbed turds on their bald spots. Physicians prescribed mercury enemas, arsenic skin cream, drinks of lead filings, and potions of human fat and skull, fresh from the executioner. The most gorgeous palaces were little better than filthy latrines. Gazing at gorgeous portraits of centuries past, we don’t see what lies beneath the royal robes and the stench of unwashed bodies; the lice feasting on private parts; and worms nesting in the intestines.In The Royal Art of Poison, Eleanor Herman combines her unique access to royal archives with cutting-edge forensic discoveries to tell the true story of Europe’s glittering palaces: one of medical bafflement, poisonous cosmetics, ever-present excrement, festering natural illness, and, sometimes, murder.

    Close worked desperately to contain the outbreak. Haunted by this wrenching crisis, Dr. Close felt compelled to honor the memory of the courageous people he knew and lost. This is their story: a terrifying, completely authentic novel that begins with an invisible killer.  It strikes without warning—a lethal disease with no name . . . and no cure.   At a Catholic mission in Yambuku, a remote village sixty miles south of the Ebola River, local teacher Mabalo Lokela visits the clinic with a raging fever. Sister Lucie, a Flemish nun and nurse, gives him a shot of an antimalarial drug, wipes off the syringe, and awaits her next patient. Within days, Mabalo is dead. Soon, others are falling ill. Less than three weeks later, the virus claims Sister Lucie’s life as well. Panic erupts, but as the villagers attempt to flee, all roads leading out of Yambuku are closed off, the dying forced back. And as the single radio connecting the mission to the outside world brings only bad news, the valiant nuns and medical personnel left behind have no choice but to pray, and wonder: Will they survive long enough for help to arrive?

    From Edward Lorenz’s discovery of the Butterfly Effect, to Mitchell Feigenbaum’s calculation of a universal constant, to Benoit Mandelbrot’s concept of fractals, which created a new geometry of nature, Gleick’s engaging narrative focuses on the key figures whose genius converged to chart an innovative direction for science. In Chaos, Gleick makes the story of chaos theory not only fascinating but also accessible to beginners, and opens our eyes to a surprising new view of the universe.

    As a result, antibiotic resistance now ranks among the gravest medical problems of modern times. Good Germs, Bad Germs addresses not only this issue but also what has become known as the "hygiene hypothesis"-- an argument that links the over-sanitation of modern life to now-epidemic increases in immune and other disorders. In telling the story of what went terribly wrong in our war on germs, Jessica Snyder Sachs explores our emerging understanding of the symbiotic relationship between the human body and its resident microbes--which outnumber its human cells by a factor of nine to one! The book also offers a hopeful look into a future in which antibiotics will be designed and used more wisely, and beyond that, to a day when we may replace antibacterial drugs and cleansers with bacterial ones--each custom-designed for maximum health benefits.

    The age-old disease spread swiftly through an increasingly interconnected American landscape: from southern tobacco plantations to the dense immigrant neighborhoods of northern cities to far-flung villages on the edges of the nascent American empire. In Pox, award-winning historian Michael Willrich offers a gripping chronicle of how the nation's continentwide fight against smallpox launched one of the most important civil liberties struggles of the twentieth century.At the dawn of the activist Progressive era and during a moment of great optimism about modern medicine, the government responded to the deadly epidemic by calling for universal compulsory vaccination. To enforce the law, public health authorities relied on quarantines, pesthouses, and "virus squads"-corps of doctors and club-wielding police. Though these measures eventually contained the disease, they also sparked a wave of popular resistance among Americans who perceived them as a threat to their health and to their rights.At the time, anti-vaccinationists were often dismissed as misguided cranks, but Willrich argues that they belonged to a wider legacy of American dissent that attended the rise of an increasingly powerful government. While a well-organized anti-vaccination movement sprang up during these years, many Americans resisted in subtler ways-by concealing sick family members or forging immunization certificates. Pox introduces us to memorable characters on both sides of the debate, from Henning Jacobson, a Swedish Lutheran minister whose battle against vaccination went all the way to the Supreme Court, to C. P. Wertenbaker, a federal surgeon who saw himself as a medical missionary combating a deadly-and preventable-disease.As Willrich suggests, many of the questions first raised by the Progressive-era antivaccination movement are still with us: How far should the government go to protect us from peril? What happens when the interests of public health collide with religious beliefs and personal conscience? In Pox, Willrich delivers a riveting tale about the clash of modern medicine, civil liberties, and government power at the turn of the last century that resonates powerfully today.

      On March 29, 1975, sisters Katherine and Sheila Lyons, ages ten and twelve, vanished from a shopping mall in suburban Washington, D.C. As shock spread, then grief, a massive police effort found nothing. The investigation was shelved, and the mystery endured.   Then, in 2013, a cold case squad detective found something he and a generation of detectives had missed. It pointed them toward a man named Lloyd Welch, then serving time for child molestation in Delaware.   The acclaimed author of Black Hawk Down and Hue 1968 had been a cub reporter for a Baltimore newspaper at the time of the original disappearance, and covered the frantic first weeks of the story. In The Last Stone, he returns to write its ending. Over months of intense questioning and extensive investigation of Welch’s sprawling, sinister Appalachian clan, five skilled detectives learned to sift truth from determined lies. How do you get a compulsive liar with every reason in the world to lie to tell the truth? The Last Stone recounts a masterpiece of criminal interrogation, and delivers a chilling and unprecedented look inside a disturbing criminal mind.

    But by itself, DNA is just an inert blueprint for life. It is the ribosome--an enormous molecular machine made up of a million atoms--that makes DNA come to life, turning our genetic code into proteins and therefore into us. Gene Machine is an insider account of the race for the structure of the ribosome, a fundamental discovery that both advances our knowledge of all life and could lead to the development of better antibiotics against life-threatening diseases. But this is also a human story of Ramakrishnan's unlikely journey, from his first fumbling experiments in a biology lab to being the dark horse in a fierce competition with some of the world's best scientists. In the end, Gene Machine is a frank insider's account of the pursuit of high-stakes science.

    With podcasts like My Favorite Murder and In the Dark, bestsellers like I’ll Be Gone in the Dark and Furious Hours, and TV hits like American Crime Story and Wild Wild Country, the cultural appetite for stories of real people doing terrible things is insatiable.Acclaimed author of The Real Lolita and editor of Women Crime Writers: Eight Suspense Novels of the 1940s & 50s (Library of America) and Troubled Daughters, Twisted Wives (Penguin), Sarah Weinman brings together an exemplary collection of recent true crime tales. She culls together some of the most refreshing and exciting contemporary journalists and chroniclers of crime working today.  Michelle Dean’s “Dee Dee Wanted Her Daughter To Be Sick” went viral when it first published and is the basis for the TV show The Act and Pamela Colloff’s “The Reckoning,” is the gold standard for forensic journalism.  There are 13 pieces in all and as a collection, they showcase writing about true crime across the broadest possible spectrum, while also reflecting what makes crime stories so transfixing and irresistible to the modern reader.

    As Farrow drew closer to the truth, shadowy operatives, from high-priced lawyers to elite war-hardened spies, mounted a secret campaign of intimidation, threatening his career, following his every move and weaponizing an account of abuse in his own family.All the while, Farrow and his producer faced a degree of resistance that could not be explained - until now. And a trail of clues revealed corruption and cover-ups from Hollywood, to Washington, and beyond.This is the untold story of the exotic tactics of surveillance and intimidation deployed by wealthy and connected men to threaten journalists, evade accountability and silence victims of abuse - and it's the story of the women who risked everything to expose the truth and spark a global movement.Both a spy thriller and a meticulous work of investigative journalism, Catch and Kill breaks devastating new stories about the rampant abuse of power - and sheds far-reaching light on investigations that shook the culture.In a dramatic account of violence and espionage, Pulitzer Prize-winning investigative reporter Ronan Farrow exposes serial abusers and a cabal of powerful interests hell-bent on covering up the truth, at any cost.

    It now has 600,000 to a million page hits daily. Every now and then, Munroe would get emails asking him to arbitrate a science debate. 'My friend and I were arguing about what would happen if a bullet got struck by lightning, and we agreed that you should resolve it . . . ' He liked these questions so much that he started up What If. If your cells suddenly lost the power to divide, how long would you survive? How dangerous is it, really, to be in a swimming pool in a thunderstorm? If we hooked turbines to people exercising in gyms, how much power could we produce? What if everyone only had one soulmate?When (if ever) did the sun go down on the British empire? How fast can you hit a speed bump while driving and live?What would happen if the moon went away?In pursuit of answers, Munroe runs computer simulations, pores over stacks of declassified military research memos, solves differential equations, and consults with nuclear reactor operators. His responses are masterpieces of clarity and hilarity, studded with memorable cartoons and infographics. They often predict the complete annihilation of humankind, or at least a really big explosion. Far more than a book for geeks, WHAT IF: Serious Scientific Answers to Absurd Hypothetical Questions explains the laws of science in operation in a way that every intelligent reader will enjoy and feel much the smarter for having read.

    A Vintage Original.Hope Jahren is an award-winning geobiologist, a brilliant writer, and one of the seven billion people with whom we share this earth. The Story of More is her impassioned open letter to humanity as we stand at the crossroads of survival and extinction. Jahren celebrates the long history of our enterprising spirit--which has tamed wild crops, cured diseases, and sent us to the moon--but also shows how that spirit has created excesses that are quickly warming our planet to dangerous levels. In short, highly readable chapters, she takes us through the science behind the key inventions--from electric power to large-scale farming and automobiles--that, even as they help us, release untenable amounts of carbon dioxide. She explains the current and projected consequences of greenhouse gases--from superstorms to rising sea levels--and the science-based tools that could help us fight back. At once an explainer on the mechanisms of warming and a capsule history of human development, The Story of More illuminates the link between our consumption habits and our endangered earth, showing us how we can use less and share more. It is the essential pocket primer on climate change that will leave an indelible impact on everyone who reads it.

    Set in Edwardian London and on the stormy coasts of Cornwall, Cape Cod, and Nova Scotia, Thunderstruck evokes the dynamism of those years when great shipping companies competed to build the biggest, fastest ocean liners, scientific advances dazzled the public with visions of a world transformed, and the rich outdid one another with ostentatious displays of wealth. Against this background, Marconi races against incredible odds and relentless skepticism to perfect his invention: the wireless, a prime catalyst for the emergence of the world we know today. Meanwhile, Crippen, “the kindest of men,” nearly commits the perfect crime. With his superb narrative skills, Erik Larson guides these parallel narratives toward a relentlessly suspenseful meeting on the waters of the North Atlantic. Along the way, he tells of a sad and tragic love affair that was described on the front pages of newspapers around the world, a chief inspector who found himself strangely sympathetic to the killer and his lover, and a driven and compelling inventor who transformed the way we communicate. Thunderstruck presents a vibrant portrait of an era of séances, science, and fog, inhabited by inventors, magicians, and Scotland Yard detectives, all presided over by the amiable and fun-loving Edward VII as the world slid inevitably toward the first great war of the twentieth century. Gripping from the first page, and rich with fascinating detail about the time, the people, and the new inventions that connect and divide us, Thunderstruck is splendid narrative history from a master of the form.

    The book documents the adverse environmental effects caused by the indiscriminate use of pesticides. Carson accused the chemical industry of spreading disinformation, and public officials of accepting the industry's marketing claims unquestioningly.The book appeared in September 1962 and the outcry that followed its publication forced the banning of DDT and spurred revolutionary changes in the laws affecting our air, land, and water. Carson’s book was instrumental in launching the environmental movement.

    After World War II, it reshaped the global order-whoever could master uranium could master the world. Marie Curie gave us hope that uranium would be a miracle panacea, but the Manhattan Project gave us reason to believe that civilization would end with apocalypse. Slave labor camps in Africa and Eastern Europe were built around mine shafts and America would knowingly send more than six hundred uranium miners to their graves in the name of national security. Fortunes have been made from this yellow dirt; massive energy grids have been run from it. Fear of it panicked the American people into supporting a questionable war with Iraq and its specter threatens to create another conflict in Iran. Now, some are hoping it can help avoid a global warming catastrophe. In "Uranium," Tom Zoellner takes readers around the globe in this intriguing look at the mineral that can sustain life or destroy it.