The Sackler name adorns the walls of many storied institutions: Harvard, the Metropolitan Museum of Art, Oxford, the Louvre. They are one of the richest families in the world, known for their lavish donations to the arts and sciences. The source of the family fortune was vague, however, until it emerged that the Sacklers were responsible for making and marketing OxyContin, a blockbuster painkiller that was a catalyst for the opioid crisis.Empire of Pain is a masterpiece of narrative reporting and writing, exhaustively documented and ferociously compelling.

    Determined to clone an endangered flower—the rare ghost orchid Polyrrhiza lindenii—a deeply eccentric and oddly attractive man named John Laroche leads Orlean on an unforgettable tour of America’s strange flower-selling subculture, through Florida’s swamps and beyond, along with the Seminoles who help him and the forces of justice who fight him. In the end, Orlean—and the reader—will have more respect for underdog determination and a powerful new definition of passion.   In this new edition, coming fifteen years after its initial publication and twenty years after she first met the “orchid thief,” Orlean revisits this unforgettable world, and the route by which it was brought to the screen in the film Adaptation, in a new retrospective essay.

    The only rock we eat, salt has shaped civilization from the very beginning, and its story is a glittering, often surprising part of the history of humankind. A substance so valuable it served as currency, salt has influenced the establishment of trade routes and cities, provoked and financed wars, secured empires, and inspired revolutions.

    They made the world theirs long before the rise of dinosaurs. Travelling forward into the Permian and then Triassic periods, we learn how our ancient mammal ancestors evolved from large hairy beasts with accelerating metabolisms to exploit miniaturisation, which was key to unlocking the traits that define mammals as we now know them. Elsa criss-crosses the globe to explore the sites where discoveries are being made and meet the people who make them. In Scotland, she traverses the desert dunes of prehistoric Moray, where quarry workers unearthed the footprints of Permian creatures from before the time of dinosaurs. In South Africa, she introduces us to animals, once called 'mammal-like reptiles', that gave scientists the first hints that our furry kin evolved from a lineage of egg-laying burrowers. In China, new, complete fossilised skeletons reveal mammals that were gliders, shovel-pawed Jurassic moles, and flat-tailed swimmers.This book radically reframes the narrative of our mammalian ancestors and provides a counterpoint to the stereotypes of mighty dinosaur overlords and cowering little mammals. It turns out the earliest mammals weren't just precursors, they were pioneers.

    . . The book works on two levels, much like a good Holmes case."--TimeFor all the scores of biographies of Arthur Conan Doyle, creator of the most famous detective in the world, there is no recent book that tells this remarkable story--in which Conan Doyle becomes a real-life detective on an actual murder case. In Conan Doyle for the Defense, Margalit Fox takes us step by step inside Conan Doyle's investigative process and illuminates a murder mystery that is also a morality play for our time--a story of ethnic, religious, and anti-immigrant bias.In 1908, a wealthy woman was brutally murdered in her Glasgow home. The police found a convenient suspect in Oscar Slater--an immigrant Jewish cardsharp--who, despite his obvious innocence, was tried, convicted, and consigned to life at hard labor in a brutal Scottish prison. Conan Doyle, already world famous as the creator of Sherlock Holmes, was outraged by this injustice and became obsessed with the case. Using the methods of his most famous character, he scoured trial transcripts, newspaper accounts, and eyewitness statements, meticulously noting myriad holes, inconsistencies, and outright fabrications by police and prosecutors. Finally, in 1927, his work won Slater's freedom.Margalit Fox, a celebrated longtime writer for The New York Times, has "a nose for interesting facts, the ability to construct a taut narrative arc, and a Dickens-level gift for concisely conveying personality" (Kathryn Schulz, New York). In Conan Doyle for the Defense, she immerses readers in the science of Edwardian crime detection and illuminates a watershed moment in the history of forensics, when reflexive prejudice began to be replaced by reason and the scientific method.Praise for Conan Doyle for the Defense"Splendid . . . The ingredients are too good to pass up: a famous detective novelist actually playing detective, a man serving time for a murder he did not commit, and a criminal justice system slowly, and reluctantly, reckoning with the advent of forensic science." -- Sarah Weinman, The New Republic "Entertaining."--Newsday

    You'll never be lost for words again.

    With its long snout and prominent teeth, it might be a crocodile – except that it has a huge, bulbous eye.Remarkable Creatures is the story of Mary Anning, who has a talent for finding fossils, and whose discovery of ancient marine reptiles such as that ichthyosaur shakes the scientific community and leads to new ways of thinking about the creation of the world.Working in an arena dominated by middle-class men, however, Mary finds herself out of step with her working-class background. In danger of being an outcast in her community, she takes solace in an unlikely friendship with Elizabeth Philpot, a prickly London spinster with her own passion for fossils.The strong bond between Mary and Elizabeth sees them through struggles with poverty, rivalry and ostracism, as well as the physical dangers of their chosen obsession. It reminds us that friendship can outlast storms and landslides, anger and jealousy.

     Elinor Cleghorn became an unwell woman ten years ago. She was diagnosed with an autoimmune disease after a long period of being told her symptoms were anything from psychosomatic to a possible pregnancy. As Elinor learned to live with her unpredictable disease she turned to history for answers, and found an enraging legacy of suffering, mystification, and misdiagnosis.In Unwell Women, Elinor Cleghorn traces the almost unbelievable history of how medicine has failed women by treating their bodies as alien and other, often to perilous effect. The result is an authoritative and groundbreaking exploration of the relationship between women and medical practice, from the wandering womb of Ancient Greece to the rise of witch trials across Europe, and from the dawn of hysteria as a catchall for difficult-to-diagnose disorders to the first forays into autoimmunity and the shifting understanding of hormones, menstruation, menopause, and conditions like endometriosis.Packed with character studies and case histories of women who have suffered, challenged, and rewritten medical orthodoxy--and the men who controlled their fate--this is a revolutionary examination of the relationship between women, illness, and medicine. With these case histories, Elinor pays homage to the women who suffered so strides could be made, and shows how being unwell has become normalized in society and culture, where women have long been distrusted as reliable narrators of their own bodies and pain. But the time for real change is long overdue: answers reside in the body, in the testimonies of unwell women--and their lives depend on medicine learning to listen.

    Would you know one if you held it in your hand?In Dark Archives, Megan Rosenbloom seeks out the historic and scientific truths behind anthropodermic bibliopegy--the practice of binding books in this most intimate covering. Dozens of such books live on in the world's most famous libraries and museums. Dark Archives exhumes their origins and brings to life the doctors, murderers, innocents, and indigents whose lives are sewn together in this disquieting collection. Along the way, Rosenbloom tells the story of how her team of scientists, curators, and librarians test rumored anthropodermic books, untangling the myths around their creation and reckoning with the ethics of their custodianship.A librarian and journalist, Rosenbloom is a member of The Order of the Good Death and a cofounder of their Death Salon, a community that encourages conversations, scholarship, and art about mortality and mourning. In Dark Archives--captivating and macabre in all the right ways--she has crafted a narrative that is equal parts detective work, academic intrigue, history, and medical curiosity: a book as rare and thrilling as its subject.

    While apocalyptic weather patterns destroyed entire harvests and incited mass migrations, they gave rise to the growth of European cities, the emergence of early capitalism, and the vigorous stirrings of the Enlightenment. A timely examination of how a society responds to profound and unexpected change, Nature’s Mutiny will transform the way we think about climate change in the twenty-first century and beyond.

    A Papua New Guinean elder shoves off in his hand-carved canoe, ready to summon a shark with ancient magic. A scientist finds a rare shark in Indonesia and forges a deal with villagers so it and other species can survive.In this eye-opening adventure that spans the globe, Juliet Eilperin investigates the fascinating ways different individuals and cultures relate to the ocean’s top predator. Along the way, she reminds us why, after millions of years, sharks remain among nature’s most awe-inspiring creatures.From Belize to South Africa, from Shanghai to Bimini, we see that sharks are still the object of an obsession that may eventually lead to their extinction. This is why movie stars and professional athletes go shark hunting in Miami and why shark’s fin soup remains a coveted status symbol in China. Yet we also see glimpses of how people and sharks can exist alongside one another: surfers tolerating their presence off Cape Town and ecotourists swimming with sharks that locals in the Yucatán no longer have to hunt.With a reporter’s instinct for a good story and a scientist’s curiosity, Eilperin offers us an up-close understanding of these extraordinary, mysterious creatures in the most entertaining and illuminating shark encounter you’re likely to find outside a steel cage.

    . . a book that enriches our understanding of how the struggle to think new thoughts is shared across time and space and people.”—The Sunday Telegraph (London)Christmas, 1859. Just one month after the publication of On the Origin of Species, Charles Darwin received an unsettling letter. He had expected criticism; in fact, letters were arriving daily, most expressing outrage and accusations of heresy. But this letter was different. It accused him of failing to acknowledge his predecessors, of taking credit for a theory that had already been discovered by others. Darwin realized that he had made an error in omitting from Origin of Species any mention of his intellectual forebears. Yet when he tried to trace all of the natural philosophers who had laid the groundwork for his theory, he found that history had already forgotten many of them.Darwin’s Ghosts tells the story of the collective discovery of evolution, from Aristotle, walking the shores of Lesbos with his pupils, to Al-Jahiz, an Arab writer in the first century, from Leonardo da Vinci, searching for fossils in the mine shafts of the Tuscan hills, to Denis Diderot in Paris, exploring the origins of species while under the surveillance of the secret police, and the brilliant naturalists of the Jardin de Plantes, finding evidence for evolutionary change in the natural history collections stolen during the Napoleonic wars. Evolution was not discovered single-handedly, Rebecca Stott argues, contrary to what has become standard lore, but is an idea that emerged over many centuries, advanced by daring individuals across the globe who had the imagination to speculate on nature’s extraordinary ways, and who had the courage to articulate such speculations at a time when to do so was often considered heresy.With each chapter focusing on an early evolutionary thinker, Darwin’s Ghosts is a fascinating account of a diverse group of individuals who, despite the very real dangers of challenging a system in which everything was presumed to have been created perfectly by God, felt compelled to understand where we came from. Ultimately, Stott demonstrates, ideas—including evolution itself—evolve just as animals and plants do, by intermingling, toppling weaker notions, and developing over stretches of time. Darwin’s Ghosts presents a groundbreaking new theory of an idea that has changed our very understanding of who we are.

     It was an ancient puzzle that stymied history's greatest minds: How did the fossils of seashells find their way far inland, sometimes high up into the mountains? Fossils only made sense in a world old enough to form them, and in the seventeenth century, few people could imagine such a thing. Texts no less authoritative than the Old Testament laid out very clearly the timescale of Earth's past; in fact one Anglican archbishop went so far as to calculate the exact date of Creation...October 23, 4004, B.C. A revolution was in the making, however, and it was started by the brilliant and enigmatic Nicholas Steno, the man whom Stephen Jay Gould called "the founder of geology." Steno explored beyond the pages of the Bible, looking directly at the clues left in the layers of the Earth. With his groundbreaking answer to the fossil question, Steno would not only confound the religious and scientific thinking of his own time, he would set the stage for the modern science that came after him. He would open the door to the concept of "deep time," which imagined a world with a history of millions or billions of years. And at the very moment his expansive new ideas began to unravel the Bible's authoritative claim as to the age of the Earth, Steno would enter the priesthood and rise to become a bishop, ultimately becoming venerated as a saint and beatified by the Catholic Church in 1988. Combining a thrilling scientific investigation with world-altering history and the portrait of an extraordinary genius, "The Seashell on the Mountaintop" gives us new insight into the very old planet on which we live, revealing how we learned to read the story told to us by the Earth itself, written in rock and stone.

    From economic development, to healthcare, to education and public policy, we rely on numbers to allocate resources and make crucial decisions. But because so much data fails to take into account gender, because it treats men as the default and women as atypical, bias and discrimination are baked into our systems. And women pay tremendous costs for this bias, in time, money, and often with their lives.Celebrated feminist advocate Caroline Criado Perez investigates the shocking root cause of gender inequality and research in Invisible Women​, diving into women’s lives at home, the workplace, the public square, the doctor’s office, and more. Built on hundreds of studies in the US, the UK, and around the world, and written with energy, wit, and sparkling intelligence, this is a groundbreaking, unforgettable exposé that will change the way you look at the world.

    Drawing deep from personal experience, cutting-edge science, and colorful history, he spins captivating stories about the birds in our midst and reveals the startlingly intimate coexistence of birds and humans.