It could be an oddball researcher’s genius insight, a catalyzing moment in geopolitical history, a new breakthrough technology, or an unexpected but welcome side effect discovered during clinical trials. Piece together these stories, as Thomas Hager does in this remarkable, century-spanning history, and you can trace the evolution of our culture and the practice of medicine.  ​Beginning with opium, the “joy plant,” which has been used for 10,000 years, Hager tells a captivating story of medicine. His subjects include the largely forgotten female pioneer who introduced smallpox inoculation to Britain, the infamous knockout drops, the first antibiotic, which saved countless lives, the first antipsychotic, which helped empty public mental hospitals, Viagra, statins, and the new frontier of monoclonal antibodies. This is a deep, wide-ranging, and wildly entertaining book.

    But its toxic effects on society are plain to see—feeding white nationalism, fueling hatred, endangering lives, and corroding our discourse on everything from sports to intelligence. Even well-intentioned people repeat stereotypes based on “science,” because cutting-edge genetics are hard to grasp—and all too easy to distort. Paradoxically, these misconceptions are multiplying even as scientists make unprecedented discoveries in human genetics—findings that, when accurately understood, are powerful evidence against racism. We’ve never had clearer answers about who we are and where we come from, but this knowledge is sorely needed in our casual conversations about race.How to Argue With a Racist emphatically dismantles outdated notions of race by illuminating what modern genetics actually can and can’t tell us about human difference. We now know that the racial categories still dividing us do not align with observable genetic differences. In fact, our differences are so minute that, most of all, they serve as evidence of our shared humanity.

    In this collection, including two never-before-published essays, Nussbaum writes about her passion for television that began with stumbling upon "Buffy the Vampire Slayer"—a show that was so much more than it appeared—while she was a graduate student studying Victorian literature. What followed was a love affair with television, an education, and a fierce debate about whose work gets to be called “great” that led Nussbaum to a trailblazing career as a critic whose reviews said so much more about our culture than just what’s good on television. Through these pieces, she traces the evolution of female protagonists over the last decade, the complex role of sexual violence on TV, and what to do about art when the artist is revealed to be a monster. And she explores the links between the television antihero and the rise of Donald Trump.The book is more than a collection of essays. With each piece, Nussbaum recounts her fervent search, over fifteen years, for a new kind of criticism that resists the false hierarchy that elevates one form of culture over another. It traces her own struggle to punch through stifling notions of “prestige television,” searching for a wilder and freer and more varied idea of artistic ambition—one that acknowledges many types of beauty and complexity, and that opens to more varied voices. It’s a book that celebrates television as television, even as each year warps the definition of just what that might mean.

    Bestselling author, artist, and illustrator Lisa Congdon brings her expertise to this guide to the process of artistic self-discovery.Find Your Artistic Voice helps artists and creatives identify and nurture their own visual identity.This one-of-a-kind book helps artists navigate the influence of creators they admire, while simultaneously appreciating the value of their personal journey.• Features down-to-earth and encouraging advice from Congdon herself• Filled with interviews with established artists, illustrators, and creatives• Answers the question "how do I develop a unique artistic style?"An artist's voice is their calling card—it's what makes each of their works vital and particular, but developing such singular artistry requires effort and persistence.Find Your Artistic Voice offers everyday strategies, inspirational anecdotes, and practical advice to push through fear and insecurity in your artistic practice.• Makes a perfect gift for aspiring artists and creatives, serious hobbyists, art students, makers, teachers, budding creative professionals, and fans of Lisa Congdon• A self-help creativity book for those looking for artistic guidance• Great for those who enjoyed reading The Artist's Way by Julia Cameron, Big Magic by Elizabeth Gilbert, and Art/Work: Everything You Need to Know (and Do) As You Pursue Your Art Career by Heather Darcy Bhandari and Jonathan Melber

    Nestled in the Appalachian mountains, Owsley County is one of the poorest counties in both Kentucky and the country. Buildings are crumbling and fields sit vacant, as tobacco farming and coal mining decline. But strong women are finding creative ways to subsist in their hollers in the hills. Cassie Chambers grew up in these hollers and, through the women who raised her, she traces her own path out of and back into the Kentucky mountains. Chambers’s Granny was a child bride who rose before dawn every morning to raise seven children. Despite her poverty, she wouldn’t hesitate to give the last bite of pie or vegetables from her garden to a struggling neighbor. Her two daughters took very different paths: strong-willed Ruth—the hardest-working tobacco farmer in the county—stayed on the family farm, while spirited Wilma—the sixth child—became the first in the family to graduate from high school, then moved an hour away for college. Married at nineteen and pregnant with Cassie a few months later, Wilma beat the odds to finish school. She raised her daughter to think she could move mountains, like the ones that kept her safe but also isolated her from the larger world. Cassie would spend much of her childhood with Granny and Ruth in the hills of Owsley County, both while Wilma was in college and after. With her “hill women” values guiding her, Cassie went on to graduate from Harvard Law. But while the Ivy League gave her knowledge and opportunities, its privileged world felt far from her reality, and she moved back home to help her fellow rural Kentucky women by providing free legal services. Appalachian women face issues that are all too common: domestic violence, the opioid crisis, a world that seems more divided by the day. But they are also community leaders, keeping their towns together in the face of a system that continually fails them. With nuance and heart, Chambers uses these women’s stories paired with her own journey to break down the myth of the hillbilly and illuminate a region whose poor communities, especially women, can lead it into the future.

    We must find and destroy her."This spy was Virginia Hall, a young American woman--rejected from the foreign service because of her gender and her prosthetic leg--who talked her way into the spy organization deemed Churchill's "ministry of ungentlemanly warfare," and, before the United States had even entered the war, became the first woman to deploy to occupied France.Virginia Hall was one of the greatest spies in American history, yet her story remains untold. Just as she did in Clementine, Sonia Purnell uncovers the captivating story of a powerful, influential, yet shockingly overlooked heroine of the Second World War. At a time when sending female secret agents into enemy territory was still strictly forbidden, Virginia Hall came to be known as the "Madonna of the Resistance," coordinating a network of spies to blow up bridges, report on German troop movements, arrange equipment drops for Resistance agents, and recruit and train guerilla fighters. Even as her face covered WANTED posters throughout Europe, Virginia refused order after order to evacuate. She finally escaped with her life in a grueling hike over the Pyrenees into Spain, her cover blown, and her associates all imprisoned or executed. But, adamant that she had "more lives to save," she dove back in as soon as she could, organizing forces to sabotage enemy lines and back up Allied forces landing on Normandy beaches. Told with Purnell's signature insight and novelistic flare, A Woman of No Importance is the breathtaking story of how one woman's fierce persistence helped win the war.

    David Starr Jordan was a taxonomist, a man possessed with bringing order to the natural world. In time, he would be credited with discovering nearly a fifth of the fish known to humans in his day. But the more of the hidden blueprint of life he uncovered, the harder the universe seemed to try to thwart him. His specimen collections were demolished by lightning, by fire, and eventually by the 1906 San Francisco earthquake—which sent more than a thousand of his discoveries, housed in fragile glass jars, plummeting to the floor. In an instant, his life’s work was shattered. Many might have given up, given in to despair. But Jordan? He surveyed the wreckage at his feet, found the first fish he recognized, and confidently began to rebuild his collection. And this time, he introduced one clever innovation that he believed would at last protect his work against the chaos of the world. When NPR reporter Lulu Miller first heard this anecdote in passing, she took Jordan for a fool—a cautionary tale in hubris, or denial. But as her own life slowly unraveled, she began to wonder about him. Perhaps instead he was a model for how to go on when all seemed lost. What she would unearth about his life would transform her understanding of history, morality, and the world beneath her feet. Part biography, part memoir, part scientific adventure, Why Fish Don’t Exist reads like a fable about how to persevere in a world where chaos will always prevail.

    Every story he wrote had one thing in common―they didn't have an ending. The killer was still out there.But after the sudden death of a friend, crime writer and author of I'll Be Gone in the Dark, Michelle McNamara, Billy became fed up. Following a dark night, he came up with a plan. A plan to investigate past the point when the cops had given up. A plan to solve the murders himself.You'll ride shotgun as Billy identifies the Halloween Mask Murderer, finds a missing girl in the California Redwoods, and investigates the only other murder in New York City on 9/11. You'll hear intimate details of the hunts for two of the most terrifying serial killers in history: his friend Michelle McNamara's pursuit of the Golden State Killer and his own quest to find the murderer of the Allenstown Four. And Billy gives you the tools―and the rules―to help solve murders yourself.Gripping, complex, unforgettable, Chase Darkness with Me is an examination of the evil forces that walk among us, illustrating a novel way to catch those killers, and a true-crime narrative unlike any you've read before.

    “This is Steve Jobs. I saw your picture in a magazine a few years ago and thought we’d work together someday.” After Steve Jobs was unceremoniously dismissed from Apple, he bought a little-known graphics company called Pixar. One day, out of the blue, Jobs called Lawrence Levy, a Harvard-trained lawyer and executive to whom he had never spoken before, to persuade Levy to help him get Pixar off the ground. What Levy found was a company on the verge of failure. To Pixar and Beyond is the story of what happened next: how, working closely with Jobs, Levy produced and implemented a highly improbable plan that transformed Pixar into one of Hollywood’s greatest success stories. Set in the worlds of Silicon Valley and Hollywood, the book takes readers inside Pixar, Disney, law firms, and investment banks. It provides an up-close, firsthand account of Pixar’s ascent, how it made creative choices, Levy’s enduring collaboration and friendship with Jobs, and how Levy came to see in Pixar deeper lessons that can apply to many aspects of our lives.

    This was, without doubt, the most celebrated cohabitation in art history: never, before or since have two such towering artistic talents been penned up in so small a space. They were the Odd Couple of art history. Predictably, the results were explosive. The dâenouement of their life together has entered into folklore. Two months after Gauguin arrived in Arles, Van Gogh suffered a psychological crisis. He spent most of the rest of his life in a mental institution. Gauguin fled from Arles, and they never saw each other again. But in the brief period during which they worked together a stream of masterpieces was created within the studio they shared. Here, for the first time, the full story of their life together is told.

    These fourteen essays are a nostalgia-soaked antidote to the millennial generation's obsession with irony, putting the aesthetics we hate to love--snakeskin pants, Sex and the City, Cheesecake Factory's gargantuan menu--into kinder and sharper perspective.Each essay revolves around a different maligned (and yet, Rax would argue, vital) cultural artifact, providing thoughtful, even romantic meditations on desire, love, and the power of nostalgia. An essay about the gym-tan-laundry exuberance of Jersey Shore morphs into an excavation of grief over the death of her father; in You Wanna Be On Top, Rax writes about friendship and early aughts girlhood; in another, Guy Fieri helps her heal from an abusive relationship.The result is a collection that captures the personal and generational experience of finding joy in caring just a little too much with clarity, heartfelt honesty, and Rax King's trademark humor.A VINTAGE ORIGINAL

    Wade have on violent crime? Freakonomics will literally redefine the way we view the modern world.These may not sound like typical questions for an economist to ask. But Steven D. Levitt is not a typical economist. He is a much heralded scholar who studies the stuff and riddles of everyday life -- from cheating and crime to sports and child rearing -- and whose conclusions regularly turn the conventional wisdom on its head. He usually begins with a mountain of data and a simple, unasked question. Some of these questions concern life-and-death issues; others have an admittedly freakish quality. Thus the new field of study contained in this book: freakonomics.Through forceful storytelling and wry insight, Levitt and co-author Stephen J. Dubner show that economics is, at root, the study of incentives -- how people get what they want, or need, especially when other people want or need the same thing. In Freakonomics, they set out to explore the hidden side of ... well, everything. The inner workings of a crack gang. The truth about real-estate agents. The myths of campaign finance. The telltale marks of a cheating schoolteacher. The secrets of the Ku Klux Klan.What unites all these stories is a belief that the modern world, despite a surfeit of obfuscation, complication, and downright deceit, is not impenetrable, is not unknowable, and -- if the right questions are asked -- is even more intriguing than we think. All it takes is a new way of looking. Steven Levitt, through devilishly clever and clear-eyed thinking, shows how to see through all the clutter.Freakonomics establishes this unconventional premise: If morality represents how we would like the world to work, then economics represents how it actually does work. It is true that readers of this book will be armed with enough riddles and stories to last a thousand cocktail parties. But Freakonomics can provide more than that. It will literally redefine the way we view the modern world.(front flap)

    In high-security, steel-walled rooms in Virginia, Walder watched al-Qaeda members with drones as President Bush looked over her shoulder and CIA Director George Tenet brought her donuts. She tracked chemical terrorists and searched the world for weapons of mass destruction. She created a chemical terror chart that someone in the White House altered to convey information she did not have or believe, leading to the Iraq invasion. Driven to stop terrorism, Walder debriefed terrorists - men who swore they’d never speak to a woman - until they gave her leads. She followed trails through North Africa, Europe, and the Middle East, shutting down multiple chemical attacks. Then Walder moved to the FBI, where she worked in counterintelligence. In a single year, she helped take down one of the most notorious foreign spies ever caught on American soil. Catching the bad guys wasn’t a problem in the FBI, but rampant sexism was. Walder left the FBI to teach young women, encouraging them to find a place in the FBI, CIA, State Department or the Senate - and thus change the world. Length: 8 hrs and 10 mins

    An apartment house-turned-hotel, it has hosted generations of gossip and folklore: 1930s bombshell Jean Harlow took lovers during her third honeymoon there; director Nicholas Ray slept with his sixteen-year-old Rebel Without a Cause star Natalie Wood; Anthony Perkins and Tab Hunter met poolside and began a secret affair; Jim Morrison swung from the balconies, once falling nearly to his death; John Belushi suffered a fatal overdose in a private bungalow; Lindsay Lohan got the boot after racking up nearly $50,000 in charges in less than two months.Perched above the Sunset Strip like a fairytale castle, the Chateau seems to come from another world entirely. Its singular appearance houses an equally singular history. While a city, an industry, and a culture have changed around it, Chateau Marmont has welcomed the most iconic and iconoclastic personalities in film, music, and media. It appeals to the rich and famous not just for its European ambiance but for its seclusion: Much of what's happened inside the Chateau's walls has eluded the public eye.Until now. With wit and prowess, Shawn Levy recounts the wild revelries and scandalous liaisons; the creative breakthroughs and marital breakdowns; the births and deaths that the Chateau has been a party to. Vivid, salacious, and richly informed, his book is a glittering tribute to Hollywood as seen from inside the walls of its most hallowed hotel.

    Mehrsa Baradaran examines how a significant portion of the population, deserted by banks, is forced to wander through a Wild West of payday lenders and check-cashing services to cover emergency expenses and pay for necessities all thanks to deregulation that began in the 1970s and continues decades later.In an age of corporate megabanks with trillions of dollars in assets, it is easy to forget that America s banking system was originally created as a public service. Banks have always relied on credit from the federal government, provided on favorable terms so that they could issue low-interest loans. But as banks grew in size and political influence, they shed their social contract with the American people, demanding to be treated as a private industry free from any public-serving responsibility. They abandoned less profitable, low-income customers in favor of wealthier clients and high-yield investments. Fringe lenders stepped in to fill the void. This two-tier banking system has become even more unequal since the 2008 financial crisis.Baradaran proposes a solution: reenlisting the U.S. Post Office in its historic function of providing bank services. The post office played an important but largely forgotten role in the creation of American democracy, and it could be deployed again to level the field of financial opportunity."