Through serendipity— by chewing, brewing, and snorting—some Neolithic souls discovered opium, alcohol, snakeroot, juniper, frankincense, and other helpful substances. Ötzi the Iceman, the five-thousand-year-old hunter frozen in the Italian Alps, was found to have whipworms in his intestines and Bronze-age medicine, a worm-killing birch fungus, knotted to his leggings. Nowadays, Big Pharma conglomerates spend billions of dollars on state-of the art laboratories staffed by PhDs to discover blockbuster drugs. Yet, despite our best efforts to engineer cures, luck, trial-and-error, risk, and ingenuity are still fundamental to medical discovery.The Drug Hunters is a colorful, fact-filled narrative history of the search for new medicines from our Neolithic forebears to the professionals of today, and from quinine and aspirin to Viagra, Prozac, and Lipitor. The chapters offer a lively tour of how new drugs are actually found, the discovery strategies, the mistakes, and the rare successes. Dr. Donald R. Kirsch infuses the book with his own expertise and experiences from thirty-five years of drug hunting, whether searching for life-saving molecules in mudflats by Chesapeake Bay or as a chief science officer and research group leader at major pharmaceutical companies.

    This is the science that people actually want to learn, shared in a friendly, engaging style. And in the spirit of science, no subject is taboo. Amid the humor is great information and cocktail conversation fodder, all thoughtfully presented. Whether you're a total newbie or the next Albert Einstein, this guide is sure to educate and entertain...ASAP.

    But with the unexpected death of her husband, her life became an empty, lightless space. Suddenly she was the single mother of two young boys, a widow at forty, clinging to three crumpled pages of instructions her husband had written for things like grocery shopping--things he had done while she did pioneering work as a planetary scientist at MIT. She became painfully conscious of her Asperger's, which before losing her husband had felt more like background noise. She felt, for the first time, alone in the universe.In this probing, invigoratingly honest memoir, Seager tells the story of how, as she stumblingly navigated the world of grief, she also kept looking for other worlds. She continues to develop groundbreaking projects, such as the Starshade, a sunflower-shaped instrument that, when launched into space, unfurls itself so as to block planet-obscuring starlight, and she takes solace in the alien beauty of exoplanets. At the same time, she discovers what feels every bit as wondrous: other people, reaching out across the space of her grief. Among them are the Widows of Concord, a group of women offering consolation and advice; and her beloved sons, Max and Alex. Most unexpected of all, there is another kind of one-in-a-billion match with an amateur astronomer.Equally attuned to the wonders of deep space and human connection, The Smallest Lights in the Universe is its own light in the dark.

    Wolke, professor emeritus of chemistry at the University of Pittsburgh and acclaimed author of What Einstein Didn't Know, understands the need to...well, understand. Now he provides more amusing explanations of such everyday phenomena as gravity (If you're in a falling elevator, will jumping at the last instant save your life?) and acoustics (Why does a whip make such a loud cracking noise?), along with amazing facts, belly-up-to-the-bar bets, and mind-blowing reality bites all with his trademark wit and wisdom.If you shoot a bullet into the air, can it kill somebody when it comes down? You can find out about all this and more in an astonishing compendium of the proverbial mind-boggling mysteries of the physical world we inhabit.Arranged in a question-and-answer format and grouped by subject for browsing ease, WHAT EINSTEIN TOLD HIS BARBER is for anyone who ever pondered such things as why colors fade in sunlight, what happens to the rubber from worn-out tires, what makes red-hot objects glow red, and other scientific curiosities. Perfect for fans of Newton's Apple, Jeopardy!, and The Discovery Channel, WHAT EINSTEIN TOLD HIS BARBER also includes a glossary of important scientific buzz words and a comprehensive index. -->

    In Wicked Plants, Stewart takes on over two hundred of Mother Nature’s most appalling creations. It’s an A to Z of plants that kill, maim, intoxicate, and otherwise offend. You’ll learn which plants to avoid (like exploding shrubs), which plants make themselves exceedingly unwelcome (like the vine that ate the South), and which ones have been killing for centuries (like the weed that killed Abraham Lincoln's mother). Menacing botanical illustrations and splendidly ghastly drawings create a fascinating portrait of the evildoers that may be lurking in your own backyard. Drawing on history, medicine, science, and legend, this compendium of bloodcurdling botany will entertain, alarm, and enlighten even the most intrepid gardeners and nature lovers.

    Its mix of adventure narrative, survival science, and practical advice has inspired everyone from business leaders to military officers, educators, and psychiatric professionals on how to take control of stress, learn to assess risk, and make better decisions under pressure.

    In a world of modern, involved, caring parents, why are so many kids aggressive and cruel?  Where is intelligence hidden in the brain, and why does that matter?  Why do cross-racial friendships decrease in schools that are more integrated?  If 98% of kids think lying is morally wrong, then why do 98% of kids lie?  What's the single most important thing that helps infants learn language?NurtureShock is a groundbreaking collaboration between award-winning science journalists Po Bronson and Ashley Merryman.  They argue that when it comes to children, we've mistaken good intentions for good ideas.  With impeccable storytelling and razor-sharp analysis, they demonstrate that many of modern society's strategies for nurturing children are in fact backfiring--because key twists in the science have been overlooked.Nothing like a parenting manual, the authors' work is an insightful exploration of themes and issues that transcend children's (and adults') lives.

    It’s also my love letter to autistic people. For too long, we have been forced to navigate a world where all the road signs are written in another language.”With a reporter’s eye and an insider’s perspective, Eric Garcia shows what it’s like to be autistic across America.Garcia began writing about autism because he was frustrated by the media’s coverage of it; the myths that the disorder is caused by vaccines, the narrow portrayals of autistic people as white men working in Silicon Valley. His own life as an autistic person didn’t look anything like that. He is Latino, a graduate of the University of North Carolina, and works as a journalist covering politics in Washington D.C. Garcia realized he needed to put into writing what so many autistic people have been saying for years; autism is a part of their identity, they don’t need to be fixed. In We’re Not Broken, Garcia uses his own life as a springboard to discuss the social and policy gaps that exist in supporting those on the spectrum. From education to healthcare, he explores how autistic people wrestle with systems that were not built with them in mind. At the same time, he shares the experiences of all types of autistic people, from those with higher support needs, to autistic people of color, to those in the LGBTQ community. In doing so, Garcia gives his community a platform to articulate their own needs, rather than having others speak for them, which has been the standard for far too long.

    We spend 90 percent of our time inside, shuttling between homes and offices, schools and stores, restaurants and gyms. And yet, in many ways, the indoor world remains unexplored territory. For all the time we spend inside buildings, we rarely stop to consider: How do these spaces affect our mental and physical well-being? Our thoughts, feelings, and behaviors? Our productivity, performance, and relationships?In this wide-ranging, character-driven book, science journalist Emily Anthes takes us on an adventure into the buildings in which we spend our days, exploring the profound, and sometimes unexpected, ways that they shape our lives. Drawing on cutting-edge research, she probes the pain-killing power of a well-placed window and examines how the right office layout can expand our social networks. She investigates how room temperature regulates our cognitive performance, how the microbes hiding in our homes influence our immune systems, and how cafeteria design affects what—and how much—we eat.Along the way, Anthes takes readers into an operating room designed to minimize medical errors, a school designed to boost students’ physical fitness, and a prison designed to support inmates’ psychological needs. And she previews the homes of the future, from the high-tech houses that could monitor our health to the 3D-printed structures that might allow us to live on the Moon.The Great Indoors provides a fresh perspective on our most familiar surroundings and a new understanding of the power of architecture and design. It's an argument for thoughtful interventions into the built environment and a story about how to build a better world—one room at a time.

    They can navigate more data than a doctor or lawyer and act with greater precision. For many years we’ve taken solace in the notion that they can’t create. But now that algorithms can learn and adapt, does the future of creativity belong to machines, too?It is hard to imagine a better guide to the bewildering world of artificial intelligence than Marcus du Sautoy, a celebrated Oxford mathematician whose work on symmetry in the ninth dimension has taken him to the vertiginous edge of mathematical understanding. In The Creativity Code he considers what machine learning means for the future of creativity. The Pollockizer can produce drip paintings in the style of Jackson Pollock, Botnik spins off fanciful (if improbable) scenes inspired by J. K. Rowling, and the music-composing algorithm Emmy managed to fool a panel of Bach experts. But do these programs just mimic, or do they have what it takes to create? Du Sautoy argues that to answer this question, we need to understand how the algorithms that drive them work―and this brings him back to his own subject of mathematics, with its puzzles, constraints, and enticing possibilities.While most recent books on AI focus on the future of work, The Creativity Code moves us to the forefront of creative new technologies and offers a more positive and unexpected vision of our future cohabitation with machines. It challenges us to reconsider what it means to be human―and to crack the creativity code.

    Guy Leschziner's patients, there is no rest for the weary in mind and body. Insomnia, narcolepsy, night terrors, sleep apnea, and sleepwalking are just a sampling of conditions afflicting sufferers who cannot sleep--and their experiences in trying are the stuff of nightmares. Demoniac hallucinations frighten people into paralysis. Restless legs rock both the sleepless and their sleeping partners with unpredictable and uncontrollable kicking. Out-of-sync circadian rhythms confuse the natural body clock's days and nights.Then there are the extreme cases. A woman in a state of deep sleep who gets dressed, unlocks her car, and drives for several miles before returning to bed. The man who has spent decades cleaning out kitchens while "sleep-eating." The teenager prone to the serious, yet unfortunately nicknamed "Sleeping Beauty Syndrome" stuck in a cycle of excessive unconsciousness, binge eating, and uncharacteristic displays of aggression and hyper-sexuality while awake.With compassionate stories of his patients and their conditions, Dr. Leschziner illustrates the neuroscience behind our sleeping minds, revealing the many biological and psychological factors necessary in getting the rest that will not only maintain our physical and mental health, but improve our cognitive abilities and overall happiness.

    Finding these forays both puzzling and exhilarating, Robb dug deeper into the science of dreams at an extremely opportune moment: just as researchers began to understand why dreams exist. They aren’t just random events; they have clear purposes. They help us learn and even overcome psychic trauma. Robb draws on fresh and forgotten research, as well as her experience and that of other dream experts, to show why dreams are vital to our emotional and physical health. She explains how we can remember our dreams better—and why we should. She traces the intricate links between dreaming and creativity, and even offers advice on how we can relish the intense adventure of lucid dreaming for ourselves.Why We Dream is a clear-eyed, cutting-edge examination of the meaning and purpose of our nightly visions and a guide to changing our dream lives—and making our waking lives richer, healthier, and happier.

    Is the apple sitting on your kitchen counter alive, or is only the apple tree it came from deserving of the word? If we can't answer that question here on earth, how will we know when and if we discover alien life on other worlds? The question hangs over some of society's most charged conflicts--whether a fertilized egg is a living person, for example, and when we ought to declare a person legally dead.Charting the obsession with Dr. Frankenstein's monster and how Coleridge came to believe the whole universe was alive, Zimmer leads us all the way into the labs and minds of researchers working on engineering life from the ground up.

    Young, MD, to offer a year's worth of medical knowledge and wellness wisdom. Each daily dose in this infectious volume offers insight into the mysterious terrain of the human body and the factors that impact its constitution.Drawn from seven diverse categories, including lifestyle and preventive medicine; the mind; medical milestones; drugs and alternative treatments; sexuality and reproduction; diseases and ailments; and children and adolescents, these 365 entries are as informative as they are functional. From aspirin to the x-ray, headaches to Hippocrates, Viagra to influenza, The Intellectual Devotional: Health will revive the mind and rejuvenate the body. Sure to please devoted intellectuals and newcomers alike, this timely volume sheds new light on an endlessly fascinating subject: ourselves.

    An experienced therapist offers groundbreaking and compassionate techniques for helping chronically inflexible children, who suffer from excessively immoderate tempers, showing how brain-based deficits contribute to these problems and offering positive and constructive ways to calm things down.