Diagnosis: Solving the Most Baffling Medical Mysteries


Lisa Sanders - 2019
    And yet she is often confounded by the cases she describes in her column: unexpected collections of symptoms that she and other physicians struggle to diagnose.A twenty-eight-year-old man, vacationing in the Bahamas for his birthday, tries some barracuda for dinner. Hours later, he collapses on the dance floor with crippling stomach pains. A middle-aged woman returns to her doctor, after visiting two days earlier with a mild rash on the back of her hands. Now the rash has turned purple and has spread across her entire body in whiplike streaks. A young elephant trainer in a traveling circus, once head-butted by a rogue zebra, is suddenly beset with splitting headaches, as if someone were "slamming a door inside his head."In each of these cases, the path to diagnosis--and treatment--is winding, sometimes frustratingly unclear. Dr. Sanders shows how making the right diagnosis requires expertise, painstaking procedure, and sometimes a little luck. Intricate, gripping, and full of twists and turns, Diagnosis puts readers in the doctor's place. It lets them see what doctors see, feel the uncertainty they feel--and experience the thrill when the puzzle is finally solved.

Remember: The Science of Memory and the Art of Forgetting


Lisa Genova - 2021
    You might even be worried that these lapses in memory could be an early sign of Alzheimer's or dementia. In reality, for the vast majority of us, these examples of forgetting are completely normal. Why? Because while memory is amazing, it is far from perfect. Our brains aren't designed to remember every name we hear, plan we make, or day we experience. Just because your memory sometimes fails doesn't mean it's broken or succumbing to disease. Forgetting is actually part of being human. In Remember, neuroscientist and acclaimed novelist Lisa Genova delves into how memories are made and how we retrieve them. You'll learn whether forgotten memories are temporarily inaccessible or erased forever and why some memories are built to exist for only a few seconds (like a passcode) while others can last a lifetime (your wedding day). You'll come to appreciate the clear distinction between normal forgetting (where you parked your car) and forgetting due to Alzheimer's (that you own a car). And you'll see how memory is profoundly impacted by meaning, emotion, sleep, stress, and context. Once you understand the language of memory and how it functions, its incredible strengths and maddening weaknesses, its natural vulnerabilities and potential superpowers, you can both vastly improve your ability to remember and feel less rattled when you inevitably forget. You can set educated expectations for your memory, and in doing so, create a better relationship with it. You don't have to fear it anymore. And that can be life-changing.

18 Tiny Deaths: The Untold Story of Frances Glessner Lee and the Invention of Modern Forensics


Bruce Goldfarb - 2020
    As the mother of forensic science, Frances Glessner Lee is the reason why homicide detectives are a thing. She is responsible for the popularity of forensic science in television shows and pop culture. Long overlooked in the history books, this extremely detailed and thoroughly researched biography will at long last tell the story of the life and contributions of this pioneering woman.

The Speckled Monster: A Historical Tale of Battling Smallpox


Jennifer Lee Carrell - 2003
    After barely surviving the agony of smallpox themselves, they flouted eighteenth-century medicine by borrowing folk knowledge from African slaves and Eastern women in frantic bids to protect their children. From their heroic struggles stems the modern science of immunology as well as the vaccinations that remain our only hope should the disease ever be unleashed again.Jennifer Lee Carrell transports readers back to the early eighteenth century to tell the tales of Lady Mary Wortley Montagu and Dr. Zabdiel Boylston, two iconoclastic figures who helped save London and Boston from the deadliest disease mankind has known.

Breaking & Mending: A Doctor’s Story of Burnout and Recovery


Joanna Cannon - 2019
    I was mentally and physically broken. So fractured, I hadn't eaten properly or slept well, or even changed my expression for months. I sat in a cubicle, behind paper-thin curtains, listening to the rest of the hospital happen around me, and I shook with the effort of not crying. I was an inch away from defeat, from the acceptance of a failure I assumed would be inevitable, but I knew I had to carry on. I had to somehow walk through it.Because I wasn't the patient. I was the doctor."A frank account of mental health from both sides of the doctor-patient divide, from the bestselling author of The Trouble with Goats and Sheep and Three Things About Elsie, based on her own experience as a doctor working on a psychiatric ward.

The Great Pretender: The Undercover Mission That Changed Our Understanding of Madness


Susannah Cahalan - 2019
    Forced to remain inside until they'd "proven" themselves sane, all eight emerged with alarming diagnoses and even more troubling stories of their treatment. Rosenhan's study broke open the field of psychiatry, closing down institutions and changing mental health diagnosis forever. But, as Cahalan's new research shows, very little in this saga is exactly as it seems. What really happened behind those closed asylum doors, and what does it mean for our understanding of mental illness today?

Ethel Rosenberg: An American Tragedy


Anne Sebba - 2021
    Both had been convicted of conspiracy to commit espionage for the Soviet Union, despite the fact that the US government was aware that the evidence against Ethel was shaky at best and based on the perjury of her own brother.This book is the first to focus on one half of that couple for more than thirty years, and much new evidence has surfaced since then. Ethel was a bright girl who might have fulfilled her personal dream of becoming an opera singer, but instead found herself struggling with the social mores of the 1950's. She longed to be a good wife and perfect mother, while battling the political paranoia of the McCarthy era, anti-Semitism, misogyny, and a mother who never valued her. Because of her profound love for and loyalty to her husband, she refused to incriminate him, despite government pressure on her to do so. Instead, she courageously faced the death penalty for a crime she hadn't committed, orphaning her children.Seventy years after her trial, this is the first time Ethel's story has been told with the full use of the dramatic and tragic prison letters she exchanged with her husband, her lawyer and her psychotherapist over a three-year period, two of them in solitary confinement. Hers is the resonant story of what happens when a government motivated by fear tramples on the rights of its citizens.

The Icepick Surgeon


Sam Kean - 2021
    But sometimes, when obsession gets the better of scientists, they twist a noble pursuit into something sinister. Under this spell, knowledge isn’t everything, it’s the only thing—no matter the cost. Bestselling author Sam Kean tells the true story of what happens when unfettered ambition pushes otherwise rational men and women to cross the line in the name of science, trampling ethical boundaries and often committing crimes in the process.The Icepick Surgeon masterfully guides the reader across two thousand years of history, beginning with Cleopatra’s dark deeds in ancient Egypt. The book reveals the origins of much of modern science in the transatlantic slave trade of the 1700s, as well as Thomas Edison’s mercenary support of the electric chair and the warped logic of the spies who infiltrated the Manhattan Project. But the sins of science aren’t all safely buried in the past. Many of them, Kean reminds us, still affect us today. We can draw direct lines from the medical abuses of Tuskegee and Nazi Germany to current vaccine hesitancy, and connect icepick lobotomies from the 1950s to the contemporary failings of mental-health care. Kean even takes us into the future, when advanced computers and genetic engineering could unleash whole new ways to do one another wrong.Unflinching, and exhilarating to the last page, The Icepick Surgeon fuses the drama of scientific discovery with the illicit thrill of a true-crime tale. With his trademark wit and precision, Kean shows that, while science has done more good than harm in the world, rogue scientists do exist, and when we sacrifice morals for progress, we often end up with neither.

Unnatural Causes: The Life and Many Deaths of Britain's Top Forensic Pathologist


Richard Shepherd - 2018
    When death is sudden or unexplained, it falls to Shepherd to establish the cause. Each post-mortem is a detective story in its own right - and Shepherd has performed over 23,000 of them. Through his skill, dedication and insight, Dr Shepherd solves the puzzle to answer our most pressing question: how did this person die?From serial killer to natural disaster, 'perfect murder' to freak accident, Shepherd takes nothing for granted in pursuit of truth. And while he's been involved in some of the most high-profile cases of recent times, it's often the less well known encounters that prove the most perplexing, intriguing and even bizarre. In or out of the public eye, his evidence has put killers behind bars, freed the innocent and turned open-and-shut cases on their heads.But a life in death, bearing witness to some of humanity's darkest corners, exacts a price and Shepherd doesn't flinch from counting the cost to him and his family.

The Genome Odyssey: Medical Mysteries and the Incredible Quest to Solve Them


Euan Angus Ashley - 2021
    Euan Ashley, Stanford professor of medicine and genetics, brings the breakthroughs of precision medicine to vivid life through the real diagnostic journeys of his patients and the tireless efforts of his fellow doctors and scientists as they hunt to prevent, predict, and beat disease.Since the Human Genome Project was completed in 2003, the price of genome sequencing has dropped at a staggering rate. It’s as if the price of a Ferrari went from $350,000 to a mere forty cents. Through breakthroughs made by Dr. Ashley’s team at Stanford and other dedicated groups around the world, analyzing the human genome has decreased from a heroic multibillion dollar effort to a single clinical test costing less than $1,000. For the first time we have within our grasp the ability to predict our genetic future, to diagnose and prevent disease before it begins, and to decode what it really means to be human.In The Genome Odyssey, Dr. Ashley details the medicine behind genome sequencing with clarity and accessibility. More than that, with passion for his subject and compassion for his patients, he introduces readers to the dynamic group of researchers and doctor detectives who hunt for answers, and to the pioneering patients who open up their lives to the medical community during their search for diagnoses and cures. He describes how he led the team that was the first to analyze and interpret a complete human genome, how they broke genome speed records to diagnose and treat a newborn baby girl whose heart stopped five times on the first day of her life, and how they found a boy with tumors growing inside his heart and traced the cause to a missing piece of his genome.These patients inspire Dr. Ashley and his team as they work to expand the boundaries of our medical capabilities and to envision a future where genome sequencing is available for all, where medicine can be tailored to treat specific diseases and to decode pathogens like viruses at the genomic level, and where our medical system as we know it has been completely revolutionized.

Vesper Flights


Helen Macdonald - 2020
    Helen Macdonald's bestselling debut H is for Hawk brought the astonishing story of her relationship with goshawk Mabel to global critical acclaim and announced Macdonald as one of this century's most important and insightful nature writers. H is for Hawk won the Samuel Johnson Prize for Nonfiction and the Costa Book Award, and was a finalist for the National Book Critics Circle Award and the Kirkus Prize for Nonfiction, launching poet and falconer Macdonald as our preeminent nature essayist, with a semi-regular column in the New York Times Magazine.In Vesper Flights Helen Macdonald brings together a collection of her best loved essays, along with new pieces on topics ranging from nostalgia for a vanishing countryside to the tribulations of farming ostriches to her own private vespers while trying to fall asleep. Meditating on notions of captivity and freedom, immigration and flight, Helen invites us into her most intimate experiences: observing songbirds from the Empire State Building as they migrate through the Tribute of Light, watching tens of thousands of cranes in Hungary, seeking the last golden orioles in Suffolk's poplar forests. She writes with heart-tugging clarity about wild boar, swifts, mushroom hunting, migraines, the strangeness of birds' nests, and the unexpected guidance and comfort we find when watching wildlife. By one of this century's most important and insightful nature writers, Vesper Flights is a captivating and foundational book about observation, fascination, time, memory, love and loss and how we make sense of the world around us.

He Wanted the Moon: The Madness and Medical Genius of Dr. Perry Baird, and His Daughter's Quest to Know Him


Mimi Baird - 2015
    Perry Baird was a rising medical star in the late 1920s and 1930s. Early in his career, ahead of his time, he grew fascinated with identifying the biochemical root of manic depression, just as he began to suffer from it himself. By the time the results of his groundbreaking experiments were published, Dr. Baird had been institutionalized multiple times, his medical license revoked, and his wife and daughters estranged. He later received a lobotomy and died from a consequent seizure, his research incomplete, his achievements unrecognized.Mimi Baird grew up never fully knowing this story, as her family went silent about the father who had been absent for most of her childhood. Decades later, a string of extraordinary coincidences led to the recovery of a manuscript which Dr. Baird had worked on throughout his brutal institutionalization, confinement, and escape. This remarkable document, reflecting periods of both manic exhilaration and clear-headed health, presents a startling portrait of a man who was a uniquely astute observer of his own condition, struggling with a disease for which there was no cure, racing against time to unlock the key to treatment before his illness became impossible to manage.Fifty years after being told her father would forever be “ill” and “away,” Mimi Baird set off on a quest to piece together the memoir and the man. In time her fingers became stained with the lead of the pencil he had used to write his manuscript, as she devoted herself to understanding who he was, why he disappeared, and what legacy she had inherited. The result of his extraordinary record and her journey to bring his name to light is He Wanted the Moon, an unforgettable testament to the reaches of the mind and the redeeming power of a determined heart.Soon to be a major motion picture, from Brad Pitt and Tony Kushner

The Undying


Anne Boyer - 2019
    For a single mother living paycheck to paycheck who had always been the caregiver rather than the one needing care, the catastrophic illness was both a crisis and an initiation into new ideas about mortality and the gendered politics of illness.A twenty-first-century Illness as Metaphor, as well as a harrowing memoir of survival, The Undying explores the experience of illness as mediated by digital screens, weaving in ancient Roman dream diarists, cancer hoaxers and fetishists, cancer vloggers, corporate lies, John Donne, pro-pain ”dolorists,” the ecological costs of chemotherapy, and the many little murders of capitalism. It excoriates the pharmaceutical industry and the bland hypocrisies of ”pink ribbon culture” while also diving into the long literary line of women writing about their own illnesses and ongoing deaths: Audre Lorde, Kathy Acker, Susan Sontag, and others.A genre-bending memoir in the tradition of The Argonauts, The Undying will break your heart, make you angry enough to spit, and show you contemporary America as a thing both desperately ill and occasionally, perversely glorious.

The Inkblots: Hermann Rorschach, His Iconic Test, and the Power of Seeing


Damion Searls - 2017
    For years he had grappled with the theories of Freud and Jung while also absorbing the aesthetic of a new generation of modern artists. He had come to believe that who we are is less a matter of what we say, as Freud thought, than what we see. Rorschach himself was a visual artist, and his test, a set of ten carefully designed inkblots, quickly made its way to America, where it took on a life of its own. Co-opted by the military after Pearl Harbor, it was a fixture at the Nuremberg trials and in the jungles of Vietnam. It became an advertising staple, a cliché in Hollywood and journalism, and an inspiration to everyone from Andy Warhol to Jay-Z. The test was also given to millions of defendants, job applicants, parents in custody battles, workers applying for jobs, and people suffering from mental illness—or simply trying to understand themselves better. And it is still used today. Damion Searls draws on unpublished letters and diaries, and a cache of previously unknown interviews with Rorschach’s family, friends, and colleagues, to tell the unlikely story of the test’s creation, its controversial reinvention, and its remarkable endurance—and what it all reveals about the power of perception. Elegant and original, The Inkblots shines a light on the twentieth century’s most visionary synthesis of art and science.

Healing Children: A Surgeon's Stories from the Frontiers of Pediatric Medicine


Kurt Newman - 2017
    As the current CEO of Children's National in Washington, D.C., the author presents an argument to place children's medical requirements and their need to thrive well into adulthood at the forefront of American medicine, and he admits that 'these kids have been my real teachers