Nestled in the Smoky Mountains of eastern Tennessee, the town of Johnson City had always seemed exempt from the anxieties of modern American life. But when the local hospital treated its first AIDS patient, a crisis that had once seemed an urban problem had arrived in the town to stay. Working in Johnson City was Abraham Verghese, a young Indian doctor specializing in infectious diseases. Dr. Verghese became by necessity the local AIDS expert, soon besieged by a shocking number of male and female patients whose stories came to occupy his mind, and even take over his life. Verghese brought a singular perspective to Johnson City: as a doctor unique in his abilities; as an outsider who could talk to people suspicious of local practitioners; above all, as a writer of grace and compassion who saw that what was happening in this conservative community was both a medical and a spiritual emergency."

    In The Poisoner's Handbook Blum draws from highly original research to track the fascinating, perilous days when a pair of forensic scientists began their trailblazing chemical detective work, fighting to end an era when untraceable poisons offered an easy path to the perfect crime. Drama unfolds case by case as the heroes of The Poisoner's Handbook—chief medical examiner Charles Norris and toxicologist Alexander Gettler—investigate a family mysteriously stricken bald, Barnum and Bailey's Famous Blue Man, factory workers with crumbling bones, a diner serving poisoned pies, and many others. Each case presents a deadly new puzzle and Norris and Gettler work with a creativity that rivals that of the most imaginative murderer, creating revolutionary experiments to tease out even the wiliest compounds from human tissue. Yet in the tricky game of toxins, even science can't always be trusted, as proven when one of Gettler's experiments erroneously sets free a suburban housewife later nicknamed "America's Lucretia Borgia" to continue her nefarious work. From the vantage of Norris and Gettler's laboratory in the infamous Bellevue Hospital it becomes clear that killers aren't the only toxic threat to New Yorkers. Modern life has created a kind of poison playground, and danger lurks around every corner. Automobiles choke the city streets with carbon monoxide; potent compounds, such as morphine, can be found on store shelves in products ranging from pesticides to cosmetics. Prohibition incites a chemist's war between bootleggers and government chemists while in Gotham's crowded speakeasies each round of cocktails becomes a game of Russian roulette. Norris and Gettler triumph over seemingly unbeatable odds to become the pioneers of forensic chemistry and the gatekeepers of justice during a remarkably deadly time. A beguiling concoction that is equal parts true crime, twentieth-century history, and science thriller, The Poisoner's Handbook is a page-turning account of a forgotten New York.

    Life On Air, his autobiography, tells the story of how he has managed to professionalise his schoolboy interests in such a remarkably successful way. Attenborough's Life On Air began in 1950, having taken a degree in Natural Sciences in the University of Cambridge, done National Service in the Navy, got married, done a year as an editor with an educational publisher, had a son and then answered a BBC recruiting ad in the Times. Turned down for BBC Radio, he was offered a traineeship in BBC TV which was pioneering the medium in Britain and he has never looked back. The rest is TV history and you can read Sir David's personal view of it all in his engaging and highly entertaining book. This is no boring story of the rise and rise of a media mogul in the smoke-filled rooms of Ally Pally and Lime Grove. Having served his apprenticeship producing programmes like Animal, Vegetable, Mineral? and Song Hunter with the famous American folk singer and song collector Alan Lomax, he managed to escape from the confines of overlit studios into the natural world. Zoo Quest began in 1954 with an animal collecting trip to Sierra Leone and David Attenborough had found his metier. Since then he has managed to bring the wonders of the natural world into millions of living rooms around the world and to reach general audiences without patronising them, without any spurious antics, silly voices or dumbing down. His animal and plant subjects are the stars, Attenborough is the master of ceremonies who introduces the acts for our wonder and amazement. But his scope extends way beyond the birds and the bees. In the 1960s, it was suggested that he took up an administrative post--"after all, you won't want to be gallivanting around the world when you are 50". Fortunately, he did not abandon gallivanting for admin but went freelance, studied anthropology and helped extend our view of native peoples and sympathies for their life styles. He went on to become responsible for coming up with famous BBC TV series such as Kenneth Clark's incredibly successful Civilisation series, followed by Bronowski's The Ascent of Man. Inevitably, he did become one of the BBC suits but one that wore a camouflage jacket. What is remarkable is that Attenborough has managed to do it for so long without really changing his own style too much. He has not had to because the technology has changed and so he has constantly been able to give new views and insights into the details of life on Earth. Writing pretty much as he speaks, it is easy to hear his voice, dry sense of humour and generosity coming through all the time. Do not expect to read personal details, navel-gazing or malicious gossip--that is not his style. The only personal note comes at the end with the death of his wife in 1997. Over 100 photos associated with the huge range of programmes he has been intimately involved with decorate Life On Air, a fascinating personal story of our times. He says that he knows of "no pleasure deeper than that which comes from contemplating the natural world and trying to understand it"; he certainly manages to convey that in Life On Air. --Douglas Palmer

    In The Beauty of Living Twice, Stone chronicles her efforts to rebuild her life and writes about her slow road back to wholeness and health. In a business that doesn’t accept failure, in a world where too many voices are silenced, Stone found the power to return, the courage to speak up, and the will to make a difference in the lives of men, women, and children around the globe.Over the course of these intimate pages, as candid as a personal conversation, Stone talks about her pivotal roles, her life-changing friendships, her worst disappointments, and her greatest accomplishments. She reveals how she went from a childhood of trauma and violence to a career in an industry that in many ways echoed those same assaults, under cover of money and glamour. She describes the strength and meaning she found in her children, and in her humanitarian efforts. And ultimately, she shares how she fought her way back to find not only her truth, but her family’s reconciliation and love.Stone made headlines not just for her beauty and her talent, but for her candor and her refusal to “play nice,” and it’s those same qualities that make this memoir so powerful. The Beauty of Living Twice is a book for the wounded and a book for the survivors; it’s a celebration of women’s strength and resilience, a reckoning, and a call to activism. It is proof that it’s never too late to raise your voice and speak out.

    A group of young scientists, under the guidance of Dr. George Church, the most brilliant geneticist of our time, works to make fantasy reality by sequencing the DNA of a frozen woolly mammoth harvested from above the Arctic circle, and splicing elements of that sequence into the DNA of a modern elephant. Will they be able to turn the hybrid cells into a functional embryo and bring the extinct creatures to life in our modern world?Along with Church and his team of Harvard scientists, a world-famous conservationist and a genius Russian scientist plan to turn a tract of the Siberian tundra into Pleistocene Park, populating the permafrost with ancient herbivores as a hedge against an environmental ticking time bomb.

     It is a remarkable portrait, too, of the life of a psychiatric asylum--the sort of community in which, for better and for worse, hundreds of thousands of people lived out their lives.More than four hundred abandoned suitcases filled with patients’ belongings were found when Willard Psychiatric Center closed in 1995 after 125 years of operation. They are skillfully examined here and compared to the written record to create a moving—and devastating—group portrait of twentieth-century American psychiatric care.

    Today he is the director of the Center for Compassion and Altruism Research and Education (CCARE) at Stanford University, of which the Dalai Lama is a founding benefactor. But back then his life was at a dead end until at twelve he wandered into a magic shop looking for a plastic thumb. Instead he met Ruth, a woman who taught him a series of exercises to ease his own suffering and manifest his greatest desires. Her final mandate was that he keep his heart open and teach these techniques to others. She gave him his first glimpse of the unique relationship between the brain and the heart.Doty would go on to put Ruth’s practices to work with extraordinary results—power and wealth that he could only imagine as a twelve-year-old, riding his orange Sting-Ray bike. But he neglects Ruth’s most important lesson, to keep his heart open, with disastrous results—until he has the opportunity to make a spectacular charitable contribution that will virtually ruin him. Part memoir, part science, part inspiration, and part practical instruction, Into the Magic Shop shows us how we can fundamentally change our lives by first changing our brains and our hearts.

    Physician, researcher, and award-winning science writer, Siddhartha Mukherjee examines cancer with a cellular biologist’s precision, a historian’s perspective, and a biographer’s passion. The result is an astonishingly lucid and eloquent chronicle of a disease humans have lived with - and perished from - for more than five thousand years. The story of cancer is a story of human ingenuity, resilience, and perseverance, but also of hubris, paternalism, and misperception. Mukherjee recounts centuries of discoveries, setbacks, victories, and deaths, told through the eyes of his predecessors and peers, training their wits against an infinitely resourceful adversary that, just three decades ago, was thought to be easily vanquished in an all-out “war against cancer.” The book reads like a literary thriller with cancer as the protagonist. From the Persian Queen Atossa, whose Greek slave cut off her malignant breast, to the nineteenth-century recipients of primitive radiation and chemotherapy to Mukherjee’s own leukemia patient, Carla, The Emperor of All Maladies is about the people who have soldiered through fiercely demanding regimens in order to survive—and to increase our understanding of this iconic disease. Riveting, urgent, and surprising, The Emperor of All Maladies provides a fascinating glimpse into the future of cancer treatments. It is an illuminating book that provides hope and clarity to those seeking to demystify cancer.

    It’s so bound up with our deepest feelings that emotional trauma causes it to change shape.Practising cardiologist Sandeep Jauhar beautifully weaves his own experiences with the defining discoveries of the past to tell the story of our most vital organ. He looks at some of the pioneers who risked their careers and their patients’ lives to better understand the heart. People like Daniel Hale Williams, who performed the world’s first documented heart surgery, and Wilson Greatbatch, who accidentally invented the pacemaker.Amid gripping scenes from the operating theatre, Jauhar interweaves stories about the patients he’s treated with the moving tale of his family’s own history of heart problems, from his grandfather’s sudden death in India – an event that sparked his life-long obsession – to the ominous signs of how he himself might die.He also confronts the limits of medical technology and argues that future progress will be determined more by how we choose to live rather than by any device we invent.

    In 2013, the New York Times published an obituary for Yvonne Brill. It began: “She made a mean beef stroganoff, followed her husband from job to job, and took eight years off from work to raise three children.” It wasn’t until the second paragraph that readers discovered why the Times had devoted several hundred words to her life: Brill was a brilliant rocket scientist who invented a propulsion system to keep communications satellites in orbit, and had recently been awarded the National Medal of Technology and Innovation. Among the questions the obituary—and consequent outcry—prompted were, Who are the role models for today’s female scientists, and where can we find the stories that cast them in their true light?      Headstrong delivers a powerful, global, and engaging response. Covering Nobel Prize winners and major innovators, as well as lesser-known but hugely significant scientists who influence our every day, Rachel Swaby’s vibrant profiles span centuries of courageous thinkers and illustrate how each one’s ideas developed, from their first moment of scientific engagement through the research and discovery for which they’re best known. This fascinating tour reveals these 52 women at their best—while encouraging and inspiring a new generation of girls to put on their lab coats.

    The emotional, incredible true story of Neil White, a man who discovers the secret to happiness, leading a fulfilling life, and the importance of fatherhood in the most unlikely of places—the last leper colony in the continental United States.

    But the president insisted there was nothing to worry about.Fortunately, we are still a nation of skeptics. Fortunately, there are those among us who study pandemics and are willing to look unflinchingly at worst-case scenarios. Michael Lewis’s taut and brilliant nonfiction thriller pits a band of medical visionaries against the wall of ignorance that was the official response of the Trump administration to the outbreak of COVID-19.The characters you will meet in these pages are as fascinating as they are unexpected. A thirteen-year-old girl’s science project on transmission of an airborne pathogen develops into a very grown-up model of disease control. A local public-health officer uses her worm’s-eye view to see what the CDC misses, and reveals great truths about American society. A secret team of dissenting doctors, nicknamed the Wolverines, has everything necessary to fight the pandemic: brilliant backgrounds, world-class labs, prior experience with the pandemic scares of bird flu and swine flu…everything, that is, except official permission to implement their work.Michael Lewis is not shy about calling these people heroes for their refusal to follow directives that they know to be based on misinformation and bad science. Even the internet, as crucial as it is to their exchange of ideas, poses a risk to them. They never know for sure who else might be listening in.

    Through the eyes of a curious scientist, she watched her mind deteriorate whereby she could not walk, talk, read, write, or recall any of her life. Because of her understanding of the brain, her respect for the cells in her body, and an amazing mother, Jill completely recovered. In My Stroke of Insight, she shares her recommendations for recovery and the insight she gained into the unique functions of the two halves of her brain. When she lost the skills of her left brain, her consciousness shifted away from normal reality where she felt "at one with the universe." Taylor helps others not only rebuild their brains from trauma, but helps those of us with normal brains better understand how we can consciously influence the neural circuitry underlying what we think, how we feel and how we react to life's circumstances.

    From its origins in 1738 as an almshouse and pesthouse, Bellevue today is a revered public hospital bringing first-class care to anyone in need. With its diverse, ailing, and unprotesting patient population, the hospital was a natural laboratory for the nation's first clinical research. It treated tens of thousands of Civil War soldiers, launched the first civilian ambulance corps and the first nursing school for women, pioneered medical photography and psychiatric treatment, and spurred New York City to establish the country's first official Board of Health. As medical technology advanced, "voluntary" hospitals began to seek out patients willing to pay for their care. For charity cases, it was left to Bellevue to fill the void. The latter decades of the twentieth century brought rampant crime, drug addiction, and homelessness to the nation's struggling cities problems that called a public hospital's very survival into question. It took the AIDS crisis to cement Bellevue's enduring place as New York's ultimate safety net, the iconic hospital of last resort.

    By the age of thirteen, he is banished to a Florida tennis camp that feels like a prison camp. Lonely, scared, a ninth-grade dropout, he rebels in ways that will soon make him a 1980s icon. He dyes his hair, pierces his ears, dresses like a punk rocker. By the time he turns pro at sixteen, his new look promises to change tennis forever, as does his lightning-fast return.And yet, despite his raw talent, he struggles early on. We feel his confusion as he loses to the world’s best, his greater confusion as he starts to win. After stumbling in three Grand Slam finals, Agassi shocks the world, and himself, by capturing the 1992 Wimbledon. Overnight he becomes a fan favorite and a media target.Agassi brings a near-photographic memory to every pivotal match and every relationship. Never before has the inner game of tennis and the outer game of fame been so precisely limned. Alongside vivid portraits of rivals from several generations—Jimmy Connors, Pete Sampras, Roger Federer—Agassi gives unstinting accounts of his brief time with Barbra Streisand and his doomed marriage to Brooke Shields. He reveals a shattering loss of confidence. And he recounts his spectacular resurrection, a comeback climaxing with his epic run at the 1999 French Open and his march to become the oldest man ever ranked number one.In clear, taut prose, Agassi evokes his loyal brother, his wise coach, his gentle trainer, all the people who help him regain his balance and find love at last with Stefanie Graf. Inspired by her quiet strength, he fights through crippling pain from a deteriorating spine to remain a dangerous opponent in the twenty-first and final year of his career. Entering his last tournament in 2006, he’s hailed for completing a stunning metamorphosis, from nonconformist to elder statesman, from dropout to education advocate. And still he’s not done. At a U.S. Open for the ages, he makes a courageous last stand, then delivers one of the most stirring farewells ever heard in a sporting arena.With its breakneck tempo and raw candor, Open will be read and cherished for years. A treat for ardent fans, it will also captivate readers who know nothing about tennis. Like Agassi’s game, it sets a new standard for grace, style, speed, and power.