Result: The world's first vaccine. Experiment: A slave woman is forced to undergo more than thirty operations without anesthesia. Result: The beginnings of modern gynecology. Experiment: From 1946 to 1953, seventy-four boys are fed oatmeal laced with radioactive iron and calcium. Result: A better understanding of the effects of radioactivity on the human body. Experimental incidents such as these paved the way for crucial medical discoveries and lifesaving cures and procedures. But they also violated the rights of their subjects, many of whom did not give their consent to the experiments. The subjects suffered excruciating pain and humiliation. Some even died as a result of the procedures. Even in the twenty-first century—despite laws, regulations, and ethical conventions—the tension between medical experimentation and patient rights continues. How do doctors balance the need to test new medicines and procedures with their ethical and moral duty to protect the rights of human subjects? What price has been paid for medical knowledge? Can we learn from the broken oaths of the past? Take a harrowing journey through some of history's greatest medical advances—and its most horrifying medical atrocities. You'll read about orphans injected with lethal tuberculosis and concentration camp inmates tortured by Nazi doctors. You’ll also learn about radiation experimentation and present-day clinical trials that prove fatal. Through these stories, explore the human suffering that has gone hand in hand with medical advancement.

    Riz is the Executive Director of Play Labs @ MIT, a video game startup incubator at the MIT Game Lab.Drawing from research and concepts from computer science, artificial intelligence, video games, quantum physics, and referencing both speculative fiction and ancient eastern spiritual texts, Virk shows how all of these traditions come together to point to the idea that we may be inside a simulated reality like the Matrix.The Simulation Hypothesis is the idea that our physical reality, far from being a solid physical universe, is part of an increasingly sophisticated video game-like simulation, where we all have multiple lives, consisting of pixels with its own internal clock run by some giant Artificial Intelligence. Simulation theory explains some of the biggest mysteries of quantum and relativistic physics, such as quantum indeterminacy, parallel universes, and the integral nature of the speed of light.Recently, the idea that we may be living in a giant video game has received a lot of attention:"There's a one in a billion chance we are not living in a simulation" -Elon Musk"I find it hard to argue we are not in a simulation." -Neil deGrasse Tyson"We are living in computer generated reality." -Philip K. DickVideo game technology has developed from basic arcade and text adventures to MMORPGs. Video game designer Riz Virk shows how these games may continue to evolve in the future, including virtual reality, augmented reality, Artificial Intelligence, and quantum computing. This book shows how this evolution could lead us to the point of being able to develop all encompassing virtual worlds like the Oasis in Ready Player One, or the simulated reality in the Matrix.While the idea sounds like science fiction, many scientists, engineers, and professors have given the Simulation Hypothesis serious consideration. Futurist Ray Kurzweil has popularized the idea of downloading our consciousness into a silicon based device, which would mean we are just digital information after all. Some, like Oxford lecturer Nick Bostrom, goes further and thinks we may in fact be artificially intelligent consciousness inside such a simulation already!But the Simulation Hypothesis is not just a modern idea. Philosophers like Plato have been telling us that we live in a "cave" and can only see shadows of the real world. Mystics of all traditions have long contended that we are living in some kind of "illusion "and that there are other realities which we can access with our minds. While even Judeo-Christian traditions have this idea, Eastern traditions like Buddhism and Hinduism make this idea part of their core tradition -- that we are inside a dream world ("Maya" or illusion, or Vishnu's Dream), and we have "multiple lives" playing different characters when one dies, continuing to gain experience and "level up" after completing certain challenges. Sounds a lot like a video game!Whether you are a computer scientist, a fan of science fiction like the Matrix movies, a video game enthusiast, or a spiritual seeker, The Simulation Hypothesis touches on all these areas, and you will never look at the world the same way again!

     When 11 year-old Sally Horner steals a notebook from the local Woolworth's, she has no way of knowing that 52 year-old Frank LaSalle, fresh out of prison, is watching her, preparing to make his move. Accosting her outside the store, Frank convinces Sally that he’s an FBI agent who can have her arrested in a minute—unless she does as he says. This chilling novel traces the next two harrowing years as Frank mentally and physically assaults Sally while the two of them travel westward from Camden to San Jose, forever altering not only her life, but the lives of her family, friends, and those she meets along the way.

    After revealing the secrets of chocolate to us, Franckie Alarcon offers a gourmet panorama of this exceptional dish that has conquered the planet! But do you really know sushi? The author traveled to Japan to meet all the players involved in the making of this true work of culinary art. From the traditional starred chef to the young cook who is shaking up the rules, including all the artisans and producers involved, this book covers the most emblematic of Japanese products from A to Z. A fascinating journey of discovery that, along the way, tells a lot about Japan itself. You’ll never believe the precision and detailed obsession with quality ingredients involved.

    But her search for the truth reveals answers she wishes she could forget in this suspenseful and deeply moving novel from the author of The Last One.What if your past wasn’t what you thought?As a child, Linda Russell was left to raise herself in a 20-acre walled-off property in rural Washington. The woods were her home, and for twelve years she lived oblivious to a stark and terrible truth: Her mother had birthed her only to replace another daughter who died in a tragic accident years before.And then one day Linda witnesses something she wasn’t meant to see. Terrified and alone, she climbs the wall and abandons her home, but her escape becomes a different kind of trap when she is thrust into the modern world—a world for which she is not only entirely unprepared, but which is unprepared to accept her.And you couldn’t see a future for yourself?Years later, Linda is living in Seattle and immersed in technology intended to connect, but she has never felt more alone. Social media continually brings her past back to haunt her, and she is hounded by the society she is now forced to inhabit. But when Linda meets a fascinating new neighbor who introduces her to the potential and escapism of virtual reality, she begins to allow herself to hope for more.What would it take to reclaim your life?Then an unexplained fire at her infamous childhood home prompts Linda to return to the property for the first time since she was a girl, unleashing a chain of events that will not only endanger her life but challenge her understanding of family, memory, and the world itself.

    He’s hungry, wet, and tired. He’s run afoul of the assassin’s guild, lost a bag of stolen goods, and bet his last penny on the local darts champion when he should have bought bread for his kids. Maybe fate needs a little help . . . As a pastiche of Sword and Sorcery, “Darts” represents the core fantasy characters and archetypes that enthusiasts love (and hate), explores their deeper motivations, and reminds us that best friends are hard to come by.

    It's a coming-of-age novel complicated by a tragic and untimely death, and it's also a novel about two sisters you will never forget. I fell in love with the confidence of the writing and the colorful nostalgia of the mid-'80s details. Our Little World will transport and transfix you.--Elin HilderbrandJuly 1985. It's a normal, sweltering New Jersey summer for soon-to-be seventh grader Bee Kocsis. Her thoughts center only on sunny days spent at Deer Chase Lake, evenings chasing fireflies around her cul-de-sac with the neighborhood kids, and Max, the boy who just moved in across the street. That and the burgeoning worry that she'll never be as special as her younger sister, Audrina, who seems to effortlessly dazzle wherever she goes.But when Max's little sister, Sally, goes missing at the lake, Bee's long-held illusion of stability is shattered in an instant. As the families in her close-knit community turn inward, suspicious, and protective, things in Bee's own home become increasingly strained, most of all with Audrina, when a shameful secret surfaces. With everything changed, Bee and Audrina's already-fraught sisterhood is pushed to the limit as they grow up--and apart--in the wake of an innocence lost too soon.Perfect for readers of Celeste Ng's Everything I Never Told You, Our Little World is a powerful and lyrical coming-of-age story that examines the complicated bond of sisterhood, the corrosive power of envy, and how the traumas of our youths can shape our identities for a lifetime.

    His attempts to achieve this monumental goal are constantly thwarted. And when his former girlfriend returns from Europe with a handsome fiancé in tow, his life becomes even more complicated. A sliver of hope appears in the form of a local TV cooking competition. Winning would offer the solution to all his problems: money for his mission and the chance to impress the girl he loves. But to win this competition, Eshaan first must face a secret that has the potential to destroy his life and his dreams. Can a young life that has been defined by a crisis ever really thrive? Will Eshaan’s pain-filled spirit ever hear the songs of salvation that the Universe sings for him, or will his demons ultimately win? Celebrated food writer Monica Bhide dishes up a page-turning story of sacrifice, determination, and an honest exploration of the human spirit. Set in contemporary India and seasoned with gentle love, dramatic loss, enchanting poetic verse, and exotic food, Karma and the Art of Butter Chicken will take you to a place where past and present keep uneasy yet delicious company. The cover photograph is by the talented and award-winning photographer, Simi Jois.

    This book helps put you in the driver's seat to embrace the journey and love your career." —Rebecca Minkoff, Founder of Rebecca Minkoff & The Female Founder CollectiveYOU ARE DESERVING OF A CAREER YOU LOVE.Fran Hauser, best-selling author of The Myth of the Nice Girl , follows up with a workbook for women who want to get more out of their careers. Embrace the Work, Love Your Career combines accessible advice, time-tested strategies, creative prompts, and thoughtful exercises into one holistic resource. Stemming from years of experience in senior leadership at Time Inc.'s People, InStyle and Entertainment Weekly as well as AOL and Coca-Cola Enterprises, Hauser centers her career guidance around six main actions:Fall in love with your careerDesign your career action planCreate time and spaceKnow your valueBuild your dream teamReflect and resetEach chapter starts with practical advice and includes prompts and exercises to help readers create their own personal career action plans. Palate-cleansing meditations and coloring breaks conclude each chapter, offering chances for calming reflection. Through simple, inspiring, and actionable tools, Embrace the Work, Love Your Career teaches women to be empowered to focus on the things that truly matter, set boundaries and, ultimately, realize their full potential.PRAISE FOR FRAN HAUSER:Named one of the "6 Most Powerful Women in NYC's Tech Scene" by Refinery29 "Is it possible to be both kind and a total badass? Yes—and Fran Hauser tells us how." — goop "Fran Hauser turns the 'nice girl' notion on its head."— Forbes "Fran gets into the mess—and gets specific—explaining how she has learned to handle all kinds of uncomfortable moments with authenticity and grace" — Refinery29

    For the next 60 years, June will dare to live boldly. She will upend conventions, risk her heart and her life, rear a child, lose a child, love more than one man, and stand up for more than one woman.June’s story will intertwine with those of three unlikely strangers: a one-time mail order bride from the Philippines, a high school music teacher, and a young mother from Mexico working as a hotel maid. Knit together around June’s explosive secret, they forge a future that none of them foresee.This jubilant, compassionate novel explores the unexpected ways that life connects us, changes us, and even perfects us. A powerful story of lust and of hope, of redemption and of compassion, In the Midnight Room is a smart, sagacious novel about womanhood, family bonds, and how we live in America now.

    While her little sister Rose is sent to the UK to keep her safe from the invading German army, Estelle is left behind on Jersey to help her grandmother run the family farm. When the Germans occupy the island, everything changes and Estelle and the islanders must face the reality of life under Nazi rule.Interspersed with letters from Rose back in London, the novel is also inspired by the real life stories from the author’s own family who were on the island during the occupation and is a true testament to the courage and bravery of the islanders.

    Joe, Florida and confessed that he’d shot and killed his parents in their family home in Silver Spring, Maryland. He said he’d been possessed by the devil. He was eventually diagnosed with schizophrenia and ruled “not criminally responsible” for the murders on grounds of insanity.But after the trial, where do the "criminally insane" go? Brottman reveals Brian's inner life leading up to the murder, as well as his complicated afterlife in a maximum security psychiatric hospital, where he is neither imprisoned nor free. During his 27 years at the hospital, Brian has tried to escape and been shot by police, and has witnessed three patient-on-patient murders. He’s experienced the drugging of patients beyond recognition, a sadistic system of rewards and punishments, and the short-lived reign of a crazed psychiatrist-turned-stalker. In the tradition of One Flew Over The Cuckoo’s Nest, Couple Found Slain is an insider’s account of life in the underworld of forensic psych wards in America and the forgotten lives of those held there, often indefinitely.

    More an encyclopedia than a field guide, National Geographic's Complete Birds is a browsable treasure trove of facts. This comprehensive volume profiles every bird observable in the continental United States and Canada, featuring species accounts with details that include calls and songs, breeding behaviors, molting patterns, and the vast extent of their polar and neotropical migrations. The precision maps, illuminating photographs, and more than 4,000 exquisite pieces of annotated art make this the biggest and best bird book ever.This third edition, thoroughly updated, includes:Information on more than 1,000 species and subspeciesOverviews of every familyOrganization reflecting current taxonomy850 range maps, more than half updated since the last editionSidebars on identification challenges such as distinguishing between Bay-breasted and Blackpoll Warblers in fall or separating the various species of white egretsThese 752 pages add up to a lifetime of learning for all devoted birders, from those just beginning birders to those who have been building their life lists for decades. Bird lovers will appreciate many other titles from National Geographic, including:Field Guide to the Birds of North AmericaBackyard Guide to the Birds of North AmericaHow to Know the Birds Birds of the Photo Ark

    Johnson had a decision to make. Just months after moving into the White House under the worst of circumstances--following the assassination of President John F. Kennedy--he had to decide whether to run to win the presidency in his own right. He turned to his most reliable, trusted political strategist: his wife, Lady Bird Johnson. The strategy memo she produced for him, emblematic of her own political acumen and largely overlooked by biographers, is just one revealing example of how their marriage was truly a decades-long political partnership.Perhaps the most underestimated First Lady of the twentieth century, Lady Bird Johnson was also one of the most accomplished and often her husband's secret weapon. Managing the White House in years of national upheaval, through the civil rights movement and the escalation of the Vietnam War, Lady Bird projected a sense of calm and, following the glamorous and modern Jackie Kennedy, an old-fashioned image of a First Lady. In truth, she was anything but. As the first First Lady to run the East Wing like a professional office, she took on her own policy initiatives, including the most ambitious national environmental effort since Teddy Roosevelt. Occupying the White House during the beginning of the women's liberation movement, she hosted professional women from all walks of life in the White House, including urban planning and environmental pioneers like Jane Jacobs and Barbara Ward, encouraging women everywhere to pursue their own careers, even if her own style of leadership and official role was to lead by supporting others.Where no presidential biographer has understood the full impact of Lady Bird Johnson's work in the White House, Julia Sweig is the first to draw substantially on Lady Bird's own voice in her White House diaries to place Claudia Alta "Lady Bird" Johnson center stage and to reveal a woman ahead of her time--and an accomplished politician in her own right.

    With his musician wife, he spends his postwar life seeking redemption—and they find it together.Graduating from Harvard at the height of World War II, brilliant mathematician Charlie Fish is assigned to the Manhattan Project. Working with some of the age’s greatest scientific minds, including J. Robert Oppenheimer, Enrico Fermi, and Leo Szilard, Charlie is assigned the task of designing and building the detonator of the atomic bomb.As he performs that work Charlie suffers a crisis of conscience, which his wife, Brenda—unaware of the true nature of Charlie’s top-secret task—mistakes as self-doubt. She urges him to set aside his qualms and continue. Once the bombs strike Hiroshima and Nagasaki, the feelings of culpability devastate him and Brenda.At the war’s end, Charlie receives a scholarship to pursue a PhD in physics at Stanford—an opportunity he and Brenda hope will allow them a fresh start. But the past proves inescapable. All any of his new colleagues can talk about is the bomb, and what greater atomic weapons might be on the horizon. Haunted by guilt, Charlie and Brenda leave Stanford and decide to dedicate the rest of their lives to making amends for the evil he helped to birth into the world.Based on the life of the actual mathematician Charles B. Fisk, Universe of Two combines riveting historical drama with a poignant love story. Stephen Kiernan has conjured a remarkable account of two people struggling to heal their consciences and find peace in a world forever changed.