From the mid-nineteenth century to the early twentieth, over 250 institutions for the insane were built throughout the United States; by 1948, they housed more than a half million patients. The blueprint for these hospitals was set by Pennsylvania hospital superintendent Thomas Story Kirkbride: a central administration building flanked symmetrically by pavilions and surrounded by lavish grounds with pastoral vistas. Kirkbride and others believed that well-designed buildings and grounds, a peaceful environment, a regimen of fresh air, and places for work, exercise, and cultural activities would heal mental illness. But in the second half of the twentieth century, after the introduction of psychotropic drugs and policy shifts toward community-based care, patient populations declined dramatically, leaving many of these beautiful, massive buildings--and the patients who lived in them--neglected and abandoned. Architect and photographer Christopher Payne spent six years documenting the decay of state mental hospitals like these, visiting seventy institutions in thirty states. Through his lens we see splendid, palatial exteriors (some designed by such prominent architects as H. H. Richardson and Samuel Sloan) and crumbling interiors--chairs stacked against walls with peeling paint in a grand hallway; brightly colored toothbrushes still hanging on a rack; stacks of suitcases, never packed for the trip home. Accompanying Payne's striking and powerful photographs is an essay by Oliver Sacks (who described his own experience working at a state mental hospital in his book Awakenings). Sacks pays tribute to Payne's photographs and to the lives once lived in these places, "where one could be both mad and safe."

    The media seized hold of the story and, in the process, helped to launch one of the most devastating health scares ever. In the years to come Wakefield would be revealed as a profiteer in league with class-action lawyers, and he would eventually lose his medical license. Meanwhile, one study after another failed to find any link between childhood vaccines and autism. Yet the myth that vaccines somehow cause developmental disorders lives on. Despite the lack of corroborating evidence, it has been popularized by media personalities such as Oprah Winfrey and Jenny McCarthy and legitimized by journalists who claim that they are just being fair to “both sides” of an issue about which there is little debate. Meanwhile, millions of dollars have been diverted from potential breakthroughs in autism research; families have spent their savings on ineffective “miracle cures"; and declining vaccination rates have led to outbreaks of deadly illnesses like Hib, measles, and whooping cough. Most tragic of all is the increasing number of children dying from vaccine-preventable diseases. In The Panic Virus Seth Mnookin draws on interviews with parents, public-health advocates, scientists, and anti-vaccine activists to tackle a fundamental question: How do we decide what the truth is? The fascinating answer helps explain everything from the persistence of conspiracy theories about 9/11 to the appeal of talk-show hosts who demand that President Obama “prove” he was born in America. The Panic Virus is the ultimate cautionary tale for our time.

    Within a few short decades the most hostile of the world’s environments had all been conquered. Likewise, in the twentieth century, medicine transformed human life. Doctors took what was routinely fatal and made it survivable. As modernity brought us ever more into different kinds of extremis, doctors pushed the bounds of medical advances and human endurance. Extreme exploration challenged the body in ways that only the vanguard of science could answer. Doctors, scientists, and explorers all share a defining trait: they push on in the face of grim odds. Because of their extreme exploration we not only understand our physiology better; we have also made enormous strides in the science of healing.Drawing on his own experience as an anesthesiologist, intensive care expert, and NASA adviser, Dr. Kevin Fong examines how cuttingedge medicine pushes the envelope of human survival by studying the human body’s response when tested by physical extremes. Extreme Medicine explores different limits of endurance and the lens each offers on one of the systems of the body. The challenges of Arctic exploration created opportunities for breakthroughs in open heart surgery; battlefield doctors pioneered techniques for skin grafts, heart surgery, and trauma care; underwater and outer space exploration have revolutionized our understanding of breathing, gravity, and much more. Avant-garde medicine is fundamentally changing our ideas about the nature of life and death.Through astonishing accounts of extraordinary events and pioneering medicine, Fong illustrates the sheer audacity of medical practice at extreme limits, where human life is balanced on a knife’s edge. Extreme Medicine is a gripping debut about the science of healing, but also about exploration in its broadest sense—and about how, by probing the very limits of our biology, we may ultimately return with a better appreciation of how our bodies work, of what life is, and what it means to be human.

    Jack Geiger, M.D., New York Times Book Review

    His goal was ambitious: to transform what would become over a hundred hours of interviews into an unprecedented portrait of Malcolm X, one that would separate fact from fiction.The result is this historic biography that conjures a never-before-seen world of its protagonist, a work whose title is inspired by a phrase Malcolm X used when he saw his Hartford followers stir with purpose, as if the dead were truly arising, to overcome the obstacles of racism. Setting Malcolm’s life not only within the Nation of Islam but against the larger backdrop of American history, the book traces the life of one of the twentieth century’s most politically relevant figures “from street criminal to devoted moralist and revolutionary.”In tracing Malcolm X’s life from his Nebraska birth in 1925 to his Harlem assassination in 1965, Payne provides searing vignettes culled from Malcolm’s Depression-era youth, describing the influence of his Garveyite parents: his father, Earl, a circuit-riding preacher who was run over by a street car in Lansing, Michigan, in 1929, and his mother, Louise, who continued to instill black pride in her children after Earl’s death. Filling each chapter with resonant drama, Payne follows Malcolm’s exploits as a petty criminal in Boston and Harlem in the 1930s and early 1940s to his religious awakening and conversion to the Nation of Islam in a Massachusetts penitentiary.With a biographer’s unwavering determination, Payne corrects the historical record and delivers extraordinary revelations—from the unmasking of the mysterious NOI founder “Fard Muhammad,” who preceded Elijah Muhammad; to a hair-rising scene, conveyed in cinematic detail, of Malcolm and Minister Jeremiah X Shabazz’s 1961 clandestine meeting with the KKK; to a minute-by-minute account of Malcolm X’s murder at the Audubon Ballroom.Introduced by Payne’s daughter and primary researcher, Tamara Payne, who, following her father’s death, heroically completed the biography, The Dead Are Arising is a penetrating and riveting work that affirms the centrality of Malcolm X to the African American freedom struggle.

    Bush describes the critical decisions that shaped his presidency and personal life.George W. Bush served as president of the United States during eight of the most consequential years in American history. The decisions that reached his desk impacted people around the world and defined the times in which we live.Decision Points brings readers inside the Texas governor’s mansion on the night of the 2000 election, aboard Air Force One during the harrowing hours after the attacks of September 11, 2001, into the Situation Room moments before the start of the war in Iraq, and behind the scenes at the White House for many other historic presidential decisions.For the first time, we learn President Bush’s perspective and insights on:His decision to quit drinking and the journey that led him to his Christian faithThe selection of the vice president, secretary of defense, secretary of state, Supreme Court justices, and other key officialsHis relationships with his wife, daughters, and parents, including heartfelt letters between the president and his father on the eve of the Iraq WarHis administration’s counterterrorism programs, including the CIA’s enhanced interrogations and the Terrorist Surveillance ProgramWhy the worst moment of the presidency was hearing accusations that race played a role in the federal government’s response to Hurricane Katrina, and a critical assessment of what he would have done differently during the crisisHis deep concern that Iraq could turn into a defeat costlier than Vietnam, and how he decided to defy public opinion by ordering the troop surgeHis legislative achievements, including tax cuts and reforming education and Medicare, as well as his setbacks, including Social Security and immigration reformThe relationships he forged with other world leaders, including an honest assessment of those he did and didn’t trustWhy the failure to bring Osama bin Laden to justice ranks as his biggest disappointment and why his success in denying the terrorists their fondest wish—attacking America again—is among his proudest achievementsA groundbreaking new brand of presidential memoir, Decision Points will captivate supporters, surprise critics, and change perspectives on eight remarkable years in American history—and on the man at the center of events.

    She'd left her husband and their medical practice in Iowa, and with only a few hundred dollars in her pocket and a great deal of pride, she set out to find a new position as a physician. She was offered a job as doctor to the miners at Bannack, Montana, and thus began her epic adventures in the Rocky Mountain West.The true story of a medicine woman who found opportunity in the wide-open spaces of America's frontier west, Pioneer Doctor: The Story of a Woman's Work, is not just a beautifully written and thoroughly researched story of a fascinating woman's life. It is also the story of an era when daring women ventured forth and changed history for the rest of us.

    But it would take the world some time to believe what had happened: the age of flight had begun, with the first heavier-than-air, powered machine carrying a pilot.Who were these men and how was it that they achieved what they did?David McCullough, two-time winner of the Pulitzer Prize, tells the surprising, profoundly American story of Wilbur and Orville Wright.Far more than a couple of unschooled Dayton bicycle mechanics who happened to hit on success, they were men of exceptional courage and determination, and of far-ranging intellectual interests and ceaseless curiosity, much of which they attributed to their upbringing. The house they lived in had no electricity or indoor plumbing, but there were books aplenty, supplied mainly by their preacher father, and they never stopped reading.When they worked together, no problem seemed to be insurmountable. Wilbur was unquestionably a genius. Orville had such mechanical ingenuity as few had ever seen. That they had no more than a public high school education, little money and no contacts in high places, never stopped them in their mission to take to the air. Nothing did, not even the self-evident reality that every time they took off in one of their contrivances, they risked being killed.In this thrilling book, master historian David McCullough draws on the immense riches of the Wright Papers, including private diaries, notebooks, scrapbooks, and more than a thousand letters from private family correspondence to tell the human side of the Wright Brothers' story, including the little-known contributions of their sister, Katharine, without whom things might well have gone differently for them.

    In a "witty, erudite, and entertaining" (Esquire) style, Simon Garfield explains how the experimental mishap that produced an odd shade of purple revolutionized fashion, as well as industrial applications of chemistry research. Occasionally honored in certain colleges and chemistry clubs, Perkin until now has been a forgotten man.

    A meld of history and science, this book is a group portrait of some of the greatest minds who ever lived as they wrestled with nature’s most sweeping mysteries. The answers they uncovered still hold the key to how we understand the world.At the end of the seventeenth century—an age of religious wars, plague, and the Great Fire of London—when most people saw the world as falling apart, these earliest scientists saw a world of perfect order. They declared that, chaotic as it looked, the universe was in fact as intricate and perfectly regulated as a clock. This was the tail end of Shakespeare’s century, when the natural land the supernatural still twined around each other. Disease was a punishment ordained by God, astronomy had not yet broken free from astrology, and the sky was filled with omens. It was a time when little was known and everything was new. These brilliant, ambitious, curious men believed in angels, alchemy, and the devil, and they also believed that the universe followed precise, mathematical laws—-a contradiction that tormented them and changed the course of history.The Clockwork Universe is the fascinating and compelling story of the bewildered geniuses of the Royal Society, the men who made the modern world.

    Yet despite the devastation, this catastrophic event seems but a forgotten moment in the United States.American Pandemic offers a much-needed corrective to the silence surrounding the influenza outbreak. It sheds light on the social and cultural history of Americans during the pandemic, uncovering both the causes of the nation's public amnesia and the depth of the quiet remembering that endured. Focused on the primary players in this drama--patients and their families, friends, and community, public health experts, and health care professionals--historian Nancy K. Bristow draws on multiple perspectives to highlight the complex interplay between social identity, cultural norms, memory, and the epidemic. Bristow has combed a wealth of primary sources, including letters, diaries, oral histories, memoirs, novels, newspapers, magazines, photographs, government documents, and health care literature. She shows that though the pandemic caused massive disruption in the most basic patterns of American life, influenza did not create long-term social or cultural change, serving instead to reinforce the status quo and the differences and disparities that defined American life.As the crisis waned the pandemic slipped from the nation's public memory. The helplessness and despair Americans had suffered during the pandemic, Bristow notes, was a story poorly suited to a nation focused on optimism and progress. For countless survivors, though, the trauma never ended, shadowing the remainder of their lives with memories of loss. This book lets us hear these long-silent voices, reclaiming an important chapter in the American past.

    The family patriarch, "the Commodore," built up a fortune that made him the world's richest man by 1877. Yet, less than fifty years after the Commodore's death, one of his direct descendants died penniless, and no Vanderbilt was counted among the world's richest people. "Fortune's Children" tells the dramatic story of all the amazingly colorful spenders who dissipated such a vast inheritance.

    In her position as America's chief diplomat, Rice traveled almost continuously around the globe, seeking common ground among sometimes bitter enemies, forging agreement on divisive issues, and compiling a remarkable record of achievement.A native of Birmingham, Alabama who overcame the racism of the Civil Rights era to become a brilliant academic and expert on foreign affairs, Rice distinguished herself as an advisor to George W. Bush during the 2000 presidential campaign. Once Bush was elected, she served as his chief adviser on national-security issues—a job whose duties included harmonizing the relationship between the Secretaries of State and Defense. It was a role that deepened her bond with the President and ultimately made her one of his closest confidantes.With the September 11, 2001, terrorist attacks, Rice found herself at the center of the Administration's intense efforts to keep America safe. Here, Rice describes the events of that harrowing day—and the tumultuous days after . No day was ever the same. Additionally, Rice also reveals new details of the debates that led to the war in Afghanistan and then Iraq.The eyes of the nation were once again focused on Rice in 2004 when she appeared before the 9-11 Commission to answer tough questions regarding the country's preparedness for—and immediate response to—the 9-11 attacks. Her responses, it was generally conceded, would shape the nation's perception of the Administration's competence during the crisis. Rice conveys just how pressure-filled that appearance was and her surprised gratitude when, in succeeding days, she was broadly saluted for her performance.From that point forward, Rice was aggressively sought after by the media and regarded by some as the Administration's most effective champion.In 2005 Rice was entrusted with even more responsibility when she was charged with helping to shape and carry forward the President's foreign policy as Secretary of State. As such, she proved herself a deft crafter of tactics and negotiation aimed to contain or reduce the threat posed by America's enemies. Here, she reveals the behind-the-scenes maneuvers that kept the world's relationships with Iran, North Korea and Libya from collapsing into chaos. She also talks about her role as a crisis manager, showing that at any hour—and at a moment's notice—she was willing to bring all parties to the bargaining table anywhere in the world.No Higher Honor takes the reader into secret negotiating rooms where the fates of Israel, the Palestinian Authority, and Lebanon often hung in the balance, and it draws back the curtain on how frighteningly close all-out war loomed in clashes involving Pakistan-India and Russia-Georgia, and in East Africa. Surprisingly candid in her appraisals of various Administration colleagues and the hundreds of foreign leaders with whom she dealt, Rice also offers here keen insight into how history actually proceeds. In No Higher Honor, she delivers a master class in statecraft—but always in a way that reveals her essential warmth and humility, and her deep reverence for the ideals on which America was founded.

    A member of the first astronaut class to include women, she broke through a quarter-century of white male fighter jocks when NASA chose her for the seventh shuttle mission, cracking the celestial ceiling and inspiring several generations of women.After a second flight, Ride served on the panels investigating the Challenger explosion and the Columbia disintegration that killed all aboard. In both instances she faulted NASA's rush to meet mission deadlines and its organizational failures. She cofounded a company promoting science and education for children, especially girls.Sherr also writes about Ride's scrupulously guarded personal life-she kept her sexual orientation private-with exclusive access to Ride's partner, her former husband, her family, and countless friends and colleagues. Sherr draws from Ride's diaries, files, and letters. This is a rich biography of a fascinating woman whose life intersected with revolutionary social and scientific changes in America. Sherr's revealing portrait is warm and admiring but unsparing. It makes this extraordinarily talented and bold woman, an inspiration to millions, come alive.

    But as a new century approached, appetites broadened, and David Fairchild, a young botanist with an insatiable lust to explore and experience the world, set out in search of foods that would enrich the American farmer and enchant the American eater.Kale from Croatia, mangoes from India, and hops from Bavaria. Peaches from China, avocados from Chile, and pomegranates from Malta. Fairchild's finds weren't just limited to food: From Egypt he sent back a variety of cotton that revolutionized an industry, and via Japan he introduced the cherry blossom tree, forever brightening America's capital. Along the way, he was arrested, caught diseases, and bargained with island tribes. But his culinary ambition came during a formative era, and through him, America transformed into the most diverse food system ever created.