As a result, antibiotic resistance now ranks among the gravest medical problems of modern times. Good Germs, Bad Germs addresses not only this issue but also what has become known as the "hygiene hypothesis"-- an argument that links the over-sanitation of modern life to now-epidemic increases in immune and other disorders. In telling the story of what went terribly wrong in our war on germs, Jessica Snyder Sachs explores our emerging understanding of the symbiotic relationship between the human body and its resident microbes--which outnumber its human cells by a factor of nine to one! The book also offers a hopeful look into a future in which antibiotics will be designed and used more wisely, and beyond that, to a day when we may replace antibacterial drugs and cleansers with bacterial ones--each custom-designed for maximum health benefits.

    In this book you will see how commonly performed operations can be found to be useless or even harmful when properly evaluated. That these claims come from an experienced, practicing orthopedic surgeon who performs many of these operations himself, makes the unsettling argument particularly compelling. Of course no surgeon is recommending invasive surgery in bad faith, but Ian Harris argues that the evidence for the success for many common operations, including knee arthroscopies, back fusion or cardiac stenting, become current accepted practice without full examination of the evidence.

    In this gripping, true account of the war against worldwide epidemics, one of medicine's frontline generals, Dr. Joseph McCormick, developer of the CDC's legendary hot zone, chronicles his decades as a virus hunter, working to combat the virus as predator. 16-pages of photos.

    Lab 257 blows the lid off the stunning true nature and checkered history of Plum Island. It shows that the seemingly bucolic island in the shadow of New York City is a ticking biological time bomb that none of us can safely ignore.Based on declassified government documents, in-depth interviews, and access to Plum Island itself, this is an eye-opening, suspenseful account of a federal government germ laboratory gone terribly wrong. For the first time, Lab 257 takes you deep inside this secret world and presents startling revelations on virus outbreaks, biological meltdowns, infected workers, the periodic flushing of contaminated raw sewage into area waters, and the insidious connections between Plum Island, Lyme disease, and the deadly West Nile virus. The book also probes what's in store for Plum Island's new owner, the Department of Homeland Security, in this age of bioterrorism.Lab 257 is a call to action for those concerned with protecting present and future generations from preventable biological catastrophes.

    Jack Geiger, M.D., New York Times Book Review

    The book has the hallmark features for which Lippincott's Illustrated Reviews volumes are so popular: an outline format, over 600 full-color illustrations, end-of-chapter summaries, review questions, plus an entire section of clinical case studies with full-color illustrations. This edition's medical/clinical focus has been sharpened to provide a high-yield review. Five additional case studies have been included, bringing the total to nineteen. Review questions have been reformatted to comply with USMLE Step 1 style, with clinical vignettes.

    That all changed in less than a generation with the discovery and development of a new category of medicine known as antibiotics. By 1955, the age-old evolutionary relationship between humans and microbes had been transformed, trivializing once-deadly infections. William Rosen captures this revolution with all its false starts, lucky surprises, and eccentric characters. He explains why, given the complex nature of bacteria—and their ability to rapidly evolve into new forms—the only way to locate and test potential antibiotic strains is by large-scale, systematic, trial-and-error experimentation. Organizing that research needs large, well-funded organizations and businesses, and so our entire scientific-industrial complex, built around the pharmaceutical company, was born. Timely, engrossing, and eye-opening, Miracle Cure is a must-read science narrative—a drama of enormous range, combining science, technology, politics, and economics to illuminate the reasons behind one of the most dramatic changes in humanity’s relationship with nature since the invention of agriculture ten thousand years ago.

    O'Connell’s collection of stories and essays, written during thirty years of caring for homeless persons in Boston, gently illuminates the humanity and raw courage of those who struggle to survive and find meaning and hope while living on the streets.

    Blending months of classroom instruction with ER rotations and a grueling field internship with the Los Angeles Fire Department, UCLA’s paramedic program is like a mix of boot camp and med school. It would turn out to be the hardest thing Grange had ever done—but also the most transformational and inspiring.An in-depth look at the trials and tragedies that paramedic students experience daily, Lights and Sirens is ultimately about the best part of humanity—people working together to help save a human life.

    It is a place where life and death meet. A place where some families celebrate the most improbable of victories while others face the most devastating of losses. A place where what matters the most in this life is revealed. Trauma Room Two is just such a place. In this collection of short stories, Dr. Green takes the reader inside the hidden emotional landscape of emergency medicine. Based on fifteen years of experience as an ER physician, he reveals the profound moments that often occur in emergency rooms for patients, their families, and the staff that work there.

    Your brain can't function. You are asked to make decisions about treatment almost immediately, when you are not in your right mind. And yet you pull yourself together and start asking questions. Beside you is your doctor, whose job it is to solve the awful puzzle of bone marrow gone wrong. The two of you are in it together. In When Blood Breaks Down, Mikkael Sekeres, a leading cancer specialist, takes readers on the journey that patient and doctor travel together.Sekeres, who writes regularly for the Well section of the New York Times, tells the compelling stories of three people who receive diagnoses of adult leukemia within hours of each other: Joan, a 48-year-old surgical nurse, a caregiver who becomes a patient; David, a 68-year-old former factory worker who bows to his family's wishes and pursues the most aggressive treatment; and Sarah, a 36-year-old pregnant woman who must decide whether to undergo chemotherapy and put her fetus at risk. We join the intimacy of the conversations Sekeres has with his patients, and watch as he teaches trainees. Along the way, Sekeres also explores leukemia in its different forms and the development of drugs to treat it--describing, among many other fascinating details, the invention of the bone marrow transplant (first performed experimentally on beagles) and a treatment that targets the genetics of leukemia.The lessons to be learned from leukemia, Sekeres shows, are not merely medical; they teach us about courage and grace and defying the odds.

    For over seventy years, since the manufacture of penicillin in 1943, we have survived extraordinary operations and life threatening conditions. We are so familiar with these wonder drugs that we take them for granted. The truth is that we have been abusing them, as patients, as doctors, as travellers, in our food.No new class of antibacterial has been discovered for over twenty-six years and the bugs are fighting back. If we do not take responsibility now, in a few decades we may start dying from the most commonplace of operations and ailments that can today be treated easily. This penguin special, by Professor Dame Sally C. Davies, the Chief Medical Officer for England, is vital in raising awareness for the future health of out children and our grandchildren.

    David Hilfiker's award-winning first book, Healing the Wounds, broke the silence surrounding the everyday practice of medicine and established him as a unique figure within the medical profession, "strikingly honest, courageous, and clear-sighted" (Oliver Sacks). In 1983, Dr. Hilfiker took on the greatest challenge of his career: he left his practice in rural Minnesota, moved with his wife and three young children to an inner-city neighborhood in Washington, D.C., and entered the world of poverty medicine. Not All of Us Are Saints vividly depicts what it means for a physician to confront the health problems of ravaged ghetto communities, for a middle-class white man to face the stark contrasts between poverty and privilege, and for a human being to admit his own spiritual limitations. Through dramatic accounts of his own cases, Dr. Hilfiker shows us a medical universe in which doctors are almost as powerless as their patients, where even the most commonplace medical solutions - bed rest, daily dosages, diet - are of little use to people without homes or family or food. This unflinching, deeply moving story is about the painful limits of care and caregivers, but it is also about the limitless rewards of faith and compassion - a moving testament to what is possible here and now.

    In this inspiring book, internationally renowned cardiologist Andrzej Szczeklik draws deeply on our humanistic heritage to describe the artistry and the mystery of being a doctor. Moving between examples ancient and contemporary, mythological and scientific, Catharsis explores how medicine and art share common roots and pose common challenge.As Szczeklik explores such subjects as the mysteries of the heart rhythm, the secret history of pain relief, the enigmatic logic of epidemics, near-death or out-of-body experiences, and many more, he skillfully weaves together classical literature, the history of medicine, and moving anecdotes from his own clinical experiences. The result is a life-affirming book that will enrich the healing work of patients and doctors alike and make an invaluable contribution to our still-expanding vision of the art of medicine.“Drawing on mathematical ideas, physics, music, mythology, clinical science and clinical practice, Szczeklik never forces the issues or compels. . . . He approaches the questions of pain, suffering and death that confront the doctor daily and that the world regards as ‘terrible, futile, and destructive.’ Here he stresses the immense value of the experienced doctor in helping patients in the loneliness of pain.”—Niall O'Higgins, Times Higher Education Supplement

    From miraculous pregnancies to dirty protests, and from violent attacks on prisoners to heartbreaking acts of self-harm, she has witnessed it all. In this memoir, Amanda reveals the stories, the patients and the cases that have shaped a career helping those most of us would rather forget.