In pursuit of these things, it is undeterred by emotion, fear, or morality. Dopamine is the source of our every urge, that little bit of biology that makes an ambitious business professional sacrifice everything in pursuit of success, or that drives a satisfied spouse to risk it all for the thrill of someone new. Simply put, it is why we seek and succeed; it is why we discover and prosper. Yet, at the same time, it’s why we gamble and squander. From dopamine’s point of view, it’s not the having that matters. It’s getting something—anything—that’s new. From this understanding—the difference between possessing something versus anticipating it—we can understand in a revolutionary new way why we behave as we do in love, business, addiction, politics, religion – and we can even predict those behaviors in ourselves and others. In The Molecule of More: How a Single Chemical in Your Brain Drives Love, Sex, and Creativity—and will Determine the Fate of the Human Race, George Washington University professor and psychiatrist Daniel Z. Lieberman, MD, and Georgetown University lecturer Michael E. Long present a potentially life-changing proposal: Much of human life has an unconsidered component that explains an array of behaviors previously thought to be unrelated, including why winners cheat, why geniuses often suffer with mental illness, why nearly all diets fail, and why the brains of liberals and conservatives really are different.

    For every one of the cells that make up the vessel that you call your body, there are nine impostor cells hitching a ride. You are not just flesh and blood, muscle and bone, brain and skin, but also bacteria and fungi. Over your lifetime, you will carry the equivalent weight of five African elephants in microbes. You are not an individual but a colony.Until recently, we had thought our microbes hardly mattered, but science is revealing a different story, one in which microbes run our bodies and becoming a healthy human is impossible without them.In this riveting, shocking, and beautifully written book, biologist Alanna Collen draws on the latest scientific research to show how our personal colony of microbes influences our weight, our immune system, our mental health, and even our choice of partner. She argues that so many of our modern diseases—obesity, autism, mental illness, digestive disorders, allergies, autoimmunity afflictions, and even cancer—have their root in our failure to cherish our most fundamental and enduring relationship: that with our personal colony of microbes.Many of the questions about modern diseases left unanswered by the Human Genome Project are illuminated by this new science. And the good news is that unlike our human cells, we can change our microbes for the better. Collen's book is a revelatory and indispensable guide. It is science writing at its most relevant: life—and your body—will never seem the same again.

    What at first seemed like a case of food poisoning quickly turned critical, and by the time Tom had been transferred via emergency medevac to the world-class medical center at UC San Diego, where both he and Steffanie worked, blood work revealed why modern medicine was failing: Tom was fighting one of the most dangerous, antibiotic-resistant bacteria in the world.Frantic, Steffanie combed through research old and new and came across phage therapy: the idea that the right virus, aka "the perfect predator," can kill even the most lethal bacteria. Phage treatment had fallen out of favor almost 100 years ago, after antibiotic use went mainstream. Now, with time running out, Steffanie appealed to phage researchers all over the world for help. She found allies at the FDA, researchers from Texas A&M, and a clandestine Navy biomedical center -- and together they resurrected a forgotten cure.

    This book tells that story, but it is not about the resurgence of pestilence. It is the story of its decline. For the first time in recorded history, virus, bacteria, and other infectious diseases are not the leading cause of death or disability in any region of the world. People are living longer, and fewer mothers are giving birth to many children in the hopes that some might survive. And yet, the news is not all good. Recent reductions in infectious disease have not been accompanied by the same improvements in income, job opportunities, and governance that occurred with these changes in wealthier countries decades ago. There have also been unintended consequences. In this book, Thomas Bollyky explores the paradox in our fight against infectious disease: the world is getting healthier in ways that should make us worry.Bollyky interweaves a grand historical narrative about the rise and fall of plagues in human societies with contemporary case studies of the consequences. Bollyky visits Dhaka--one of the most densely populated places on the planet--to show how low-cost health tools helped enable the phenomenon of poor world megacities. He visits China and Kenya to illustrate how dramatic declines in plagues have affected national economies. Bollyky traces the role of infectious disease in the migrations from Ireland before the potato famine and to Europe from Africa and elsewhere today.Historic health achievements are remaking a world that is both worrisome and full of opportunities. Whether the peril or promise of that progress prevails, Bollyky explains, depends on what we do next.A Council on Foreign Relations Book

    But internal problems of corruption, popular unrest, and dwindling finances had weakened China far more than was commonly understood, and the war would help set in motion the eventual fall of the Qing dynasty--which, in turn, would lead to the rise of nationalism and communism in the twentieth century. As one of the most potent turning points in the country's modern history, the Opium War has since come to stand for everything that today's China seeks to put behind it.In this dramatic, epic story, award-winning historian Stephen Platt sheds new light on the early attempts by Western traders and missionaries to "open" China--traveling mostly in secret beyond Canton, the single port where they were allowed--even as China's imperial rulers were struggling to manage their country's decline and Confucian scholars grappled with how to use foreign trade to China's advantage. The book paints an enduring portrait of an immensely profitable--and mostly peaceful--meeting of civilizations at Canton over the long term that was destined to be shattered by one of the most shockingly unjust wars in the annals of imperial history. Brimming with a fascinating cast of British, Chinese, and American individuals, this riveting narrative of relations between China and the West has important implications for today's uncertain and ever-changing political climate.

    It is essentially a death sentence. The only accepted form of treatment - starvation - whittles her down to forty-five pounds skin and bones. Miles away, Canadian researchers Frederick Banting and Charles Best manage to identify and purify insulin from animal pancreases - a miracle soon marred by scientific jealousy, intense business competition and fistfights. In a race against time and a ravaging disease, Elizabeth becomes one of the first diabetics to receive insulin injections - all while its discoverers and a little known pharmaceutical company struggle to make it available to the rest of the world.Relive the heartwarming true story of the discovery of insulin as it's never been told before. Written with authentic detail and suspense, and featuring walk-ons by William Howard Taft, Woodrow Wilson, and Eli Lilly himself, among many others.

    With a chapter for each of ten cocktails--from the grog sailors drank on the high seas in the 1700s to the mojitos of modern club hoppers--Wayne Curtis reveals that the homely spirit once distilled from the industrial waste of the exploding sugar trade has managed to infiltrate every stratum of New World society. Curtis takes us from the taverns of the American colonies, where rum delivered both a cheap wallop and cash for the Revolution, to the plundering pirate ships off the coast of Central America, to the watering holes of pre-Castro Cuba, and to the kitsch-laden tiki bars of 1950s America. Here are sugar barons and their armies conquering the Caribbean, Paul Revere stopping for a nip during his famous ride, Prohibitionists marching against "demon rum," Hemingway fattening his liver with Havana daiquiris, and today's bartenders reviving old favorites like Planter's Punch. In an age of microbrewed beer and single-malt whiskeys, rum--once the swill of the common man--has found its way into the tasting rooms of the most discriminating drinkers. Awash with local color and wry humor, "And a Bottle of Rum" is an affectionate toast to this most American of liquors, a chameleon spirit that has been constantly reinvented over the centuries by tavern keepers, bootleggers, lounge lizards, and marketing gurus. Complete with cocktail recipes for would-be epicurean time-travelers, this is history at its most intoxicating.

    Facing such horrors, many patients ran with open arms to burgeoning practices that promised new ways to cure their ills. Hydropaths offered cures using “healing waters” and tight wet-sheet wraps. Phineas Parkhurst Quimby experimented with magnets and tried to replace “bad,” diseased thoughts with “good,” healthy thoughts, while Daniel David Palmer reportedly restored a man’s hearing by knocking on his vertebrae. Lorenzo and Lydia Fowler used their fingers to “read” their clients’ heads, claiming that the topography of one’s skull could reveal the intricacies of one’s character. Lydia Pinkham packaged her Vegetable Compound and made a famous family business from the homemade cure-all. And Samuel Thomson, rejecting traditional medicine, introduced a range of herbal remedies for a vast array of woes, supplemented by the curative powers of poetry.   Bizarre as these methods may seem, many are the precursors of today’s notions of healthy living. We have the nineteenth-century practice of “medical gymnastics” to thank for today’s emphasis on regular exercise, and hydropathy’s various water cures for the notion of regular bathing and the mantra to drink “eight glasses of water a day.” And much of the philosophy of health introduced by these alternative methods is reflected in today’s patient-centered care and holistic medicine, which takes account of the body and spirit. Moreover, these entrepreneurial alternative healers paved the way for women in medicine. Shunned by the traditionalists and eager for converts, many of the masters of these new fields embraced the training of women in their methods. Some women, like Pinkham, were able to break through the barriers to women working to become medical entrepreneurs themselves. In fact, next to teaching, medicine attracted more women than any other profession in the nineteenth century, the majority of them in “irregular” health systems.   These eccentric ideas didn’t make it into modern medicine without a fight, of course. As these new healing methods grew in popularity, traditional doctors often viciously attacked them with cries of “quackery” and pressed legal authorities to arrest, fine, and jail irregulars for endangering public safety. Nonetheless, these alternative movements attracted widespread support—from everyday Americans and the famous alike, including Mark Twain, Louisa May Alcott, and General Ulysses S. Grant—with their messages of hope, self-help, and personal empowerment.   Though many of these medical fads faded, and most of their claims of magical cures were discredited by advances in medical science, a surprising number of the theories and ideas behind the quackery are staples in today’s health industry. Janik tells the colorful stories of these “quacks,” whose oftentimes genuine wish to heal helped shape and influence modern medicine.

    Judy Melinek began her training as a New York City forensic pathologist. With her husband T.J. and their toddler Daniel holding down the home front, Judy threw herself into the fascinating world of death investigation, performing autopsies, investigating death scenes, counseling grieving relatives. Working Stiff chronicles Judy's two years of training, taking readers behind the police tape of some of the most harrowing deaths in the Big Apple, including a firsthand account of the events of September 11, the subsequent anthrax bio-terrorism attack, and the disastrous crash of American Airlines flight 587.Lively, action-packed, and loaded with mordant wit, Working Stiff offers a firsthand account of daily life in one of America's most arduous professions, and the unexpected challenges of shuttling between the domains of the living and the dead. The body never lies, and through the murders, accidents, and suicides that land on her table, Dr. Melinek lays bare the truth behind the glamorized depictions of autopsy work on shows like CSI and Law and Order to reveal the secret story of the real morgue.

    Two years later, Clea Koff, a twenty-three-year-old forensic anthropologist, left the safe confines of a lab in Berkeley, California, to serve as one of sixteen scientists chosen by the United Nations to unearth the physical evidence of the Rwandan genocide. Over the next four years, Koff’s grueling investigations took her across geography synonymous with some of the worst crimes of the twentieth century. The Bone Woman is Koff’s unflinching, riveting account of her seven UN missions to Bosnia, Croatia, Kosovo, and Rwanda, as she shares what she saw, how it affected her, who was prosecuted based on evidence she found, and what she learned about the world. Yet even as she recounts the hellish nature of her work and the heartbreak of the survivors, she imbues her story with purpose, humanity, and a sense of justice. A tale of science in service of human rights, The Bone Woman is, even more profoundly, a story of hope and enduring moral principles.

    Arthur Allen reveals a history of vaccination that is both illuminated with hope and shrouded by controversy - covering Jenner's discovery to Pasteur's vaccines for rabies and cholera, to those that safeguarded the children of the 20th century.

    It's the most miraculous substance on earth, responsible for our food, our weather, our water, and our ability to hear. In this exuberant book, gifted science writer Gabrielle Walker peels back the layers of our atmosphere with the stories of the people who uncovered its secrets: - A flamboyant Renaissance Italian discovers how heavy our air really is: The air filling Carnegie Hall, for example, weighs seventy thousand pounds. - A one-eyed barnstorming pilot finds a set of winds that constantly blow five miles above our heads. - An impoverished American farmer figures out why hurricanes move in a circle by carving equations with his pitchfork on a barn door. - A well-meaning inventor nearly destroys the ozone layer. - A reclusive mathematical genius predicts, thirty years before he's proved right, that the sky contains a layer of floating metal fed by the glowing tails of shooting stars.

    Medical science has made brilliant discoveries over the last century but as any cancer patient can attest, it has yet to conquer, or even fully comprehend, pain. Beginning with his own battle against severe migraines, and citing numerous case studies of his patients, in Why We Hurt Dr. Frank Vertosick explains how pain evolved, and by highlighting the critical functions it serves, he helps us to understand its value. Well written, expertly researched, and movingly told, each chapter offers an amalgam of medicine, history, anthropology, drama, inspiration, and practical advice on a myriad of pain syndromes, from back pain to angina, arthritis to carpal tunnel syndrome. A skilled writer and compassionate physician, Vertosick believes knowledge is often the first, and best, analgesic, and in Why We Hurt, "he offers fascinating insight into the greatest mystery of all: what it means to be human" (The Seattle Times).

    Smith and Lourie ingested and inhaled a host of things that surround all of us all the time. This book exposes the extent to which we are poisoned every day of our lives. For this book, over the period of a week - the kind of week that would be familiar to most people - the authors use their own bodies as the reference point and tell the story of pollution in our modern world, the miscreant corporate giants who manufacture the toxins, the weak-kneed government officials who let it happen, and the effects on people and families across the globe. Parents and concerned citizens will have to read this book.Key concerns raised in Slow Death by Rubber Duck:• Flame-retardant chemicals from electronics and household dust polluting our blood. • Toxins in our urine caused by leaching from plastics and run-of-the-mill shampoos, toothpastes and deodorant.• Mercury in our blood from eating tuna.• The chemicals that build up in our body when carpets and upholstery off-gas.Ultimately hopeful, the book empowers readers with some simple ideas for protecting themselves and their families, and changing things for the better.From the Hardcover edition.

    But it’s also messy, fallible, and about 50,000 years out of date. We cling to superstitions, remember faces but not names, miss things sitting right in front of us, and lie awake at night while our brains endlessly replay our greatest fears. Idiot Brain is for anyone who has ever wondered why their brain appears to be sabotaging their life—and what on earth it is really up to.A Library Journal Science Bestseller and a Finalist for the Goodreads Choice Award in Science Technology.