Now comes a gripping account of the doctors and scientists fighting to protect us, an urgent wake-up call about the future of emerging viruses—from the #1 bestselling author of The Hot Zone, soon to be a National Geographic original miniseries.This time, Ebola started with a two-year-old child who likely had contact with a wild creature and whose entire family quickly fell ill and died. The ensuing global drama activated health professionals in North America, Europe, and Africa in a desperate race against time to contain the viral wildfire. By the end—as the virus mutated into its deadliest form, and spread farther and faster than ever before—30,000 people would be infected, and the dead would be spread across eight countries on three continents.In this taut and suspenseful medical drama, Richard Preston deeply chronicles the outbreak, in which we saw for the first time the specter of Ebola jumping continents, crossing the Atlantic, and infecting people in America. Rich in characters and conflict—physical, emotional, and ethical—Crisis in the Red Zone is an immersion in one of the great public health calamities of our time.Preston writes of doctors and nurses in the field putting their own lives on the line, of government bureaucrats and NGO administrators moving, often fitfully, to try to contain the outbreak, and of pharmaceutical companies racing to develop drugs to combat the virus. He also explores the charged ethical dilemma over who should and did receive the rare doses of an experimental treatment when they became available at the peak of the disaster. Crisis in the Red Zone makes clear that the outbreak of 2013–2014 is a harbinger of further, more severe outbreaks, and of emerging viruses heretofore unimagined—in any country, on any continent. In our ever more interconnected world, with roads and towns cut deep into the jungles of equatorial Africa, viruses both familiar and undiscovered are being unleashed into more densely populated areas than ever before.The more we discover about the virosphere, the more we realize its deadly potential. Crisis in the Red Zone is an exquisitely timely book, a stark warning of viral outbreaks to come.

    But AIDS is just one of the many emerging viruses for which we have, as yet, no cure. Even the old plagues – TB, cholera, bubonic plague – are making a comeback, resistant now to our drugs.Frank Ryan, a leading authority on disease, describes the groundbreaking research of the world’s leading experts in the field to show both where these viruses come from and why they prove to be so lethal, and advances a radical new biological theory for the origins and behaviour of plague viruses. Full of vivid despatches from the front line of research and medicine, 'Virus X' is terrifying and essential reading for anyone interested in the effects of plague viruses on human evolution.“Extremely well written…Frank Ryan has the page-turning and spine-chilling ability of a good novelist”MATT RIDLEY, 'Sunday Telegraph'“Compelling and frightening…the plot could not be bettered”MICHAEL SMITH, 'Scotsman'“Ryan is very good at making technical matters comprehensible to the lay reader but more impressive still is the way he conveys the intellectual excitement and elation of scientific discovery”ANTHONY DANIELS, 'Literary Review'“Ryan takes us through the drama of discovery and challenges the notion that certain questions are too appalling to contemplate”DAVID BRADLEY, 'New Scientist'“Dr Ryan writes well in a difficult technical field, weaving the technicalities of scientific history, medicine, molecular biology and evolution into the human narratives…very readable and disturbing”JOHN R.G. TURNER, 'New York Times'

    However, scant attention has been paid to the two women who were closest to him: Renee Pelagie de Sade, his adoring wife, and his powerful mother-in-law, Madame de Montreuil.Francine du Plessix Gray draws on thousands of pages of letters exchanged by the married couple, few of which have been published before in English, to explore in the fullest historical and psychological detail what it was like to be married to one of the most maverick spirits of modern history. Gray brings to life two remarkable women and their complex relationship to Sade as they dedicated themselves to protecting him from the law, curbing his excesses, and ultimately confining him. With immediacy, irony, and verve, At Home with the Marquis de Sade also conjures up the extravagant hedonism and terror of late eighteenth-century France.

    "Judith Thompson hears the poetry of the inarticulate and the semi-literate, embodying the colloquialisms, the brand names, the fractured but expressive syntax, with the urgency of their speakers. These characters do terrible things, and they have terrible things done to them."—Urjo Kareda

    Smallpox. Incurable and horrifying Ebola-related fevers. For two decades, while a fearful world prepared for nuclear winter, an elite team of Russian bioweaponeers began to till a new killing field: a bleak tract sown with powerful seeds of mass destruction—by doctors who had committed themselves to creating a biological Armageddon. Biohazard is the never-before-told story of Russia’s darkest, deadliest, and most closely guarded Cold War secret.   No one knows more about Russia’s astounding experiments with biowarfare than Ken Alibek. Now the mastermind behind Russia’s germ warfare effort reveals two decades of shocking breakthroughs . . . how Moscow’s leading scientists actually reengineered hazardous microbes to make them even more virulent . . . the secrets behind the discovery of an invisible, untraceable new class of biological agents just right for use in political assassinations . . . the startling story behind Russia’s attempt to turn a sample of the AIDS virus into the ultimate bioweapon. And in a chilling work of real-world intrigue, Biohazard offers us all a rare glimpse into a shadowy scientific underworld where doctors manufacture mass destruction, where witnesses to errors are silenced forever, and where ground zero is closer than we ever dared believe.

    And as outbreaks of COVID-19, Ebola, MERS, and Zika have demonstrated, we are woefully underprepared to deal with the fallout. So what can -- and must -- we do in order to protect ourselves from mankind's deadliest enemy?Drawing on the latest medical science, case studies, policy research, and hard-earned epidemiological lessons, Deadliest Enemy explores the resources and programs we need to develop if we are to keep ourselves safe from infectious disease. The authors show how we could wake up to a reality in which many antibiotics no longer cure, bioterror is a certainty, and the threat of a disastrous influenza or coronavirus pandemic looms ever larger. Only by understanding the challenges we face can we prevent the unthinkable from becoming the inevitable.Deadliest Enemy is high scientific drama, a chronicle of medical mystery and discovery, a reality check, and a practical plan of action.

    If such a plague returned today, taking a comparable percentage of the U.S. population with it, 1.5 million Americans would die.The fascinating, true story of the world's deadliest disease.In 1918, the Great Flu Epidemic felled the young and healthy virtually overnight. An estimated forty million people died as the epidemic raged. Children were left orphaned and families were devastated. As many American soldiers were killed by the 1918 flu as were killed in battle during World War I. And no area of the globe was safe. Eskimos living in remote outposts in the frozen tundra were sickened and killed by the flu in such numbers that entire villages were wiped out.Scientists have recently rediscovered shards of the flu virus frozen in Alaska and preserved in scraps of tissue in a government warehouse. Gina Kolata, an acclaimed reporter for "The New York Times," unravels the mystery of this lethal virus with the high drama of a great adventure story. Delving into the history of the flu and previous epidemics, detailing the science and the latest understanding of this mortal disease, Kolata addresses the prospects for a great epidemic recurring, and, most important, what can be done to prevent it.

    It is well known that some Americans are obsessed with conspiracies. The Kennedy assassination, the Oklahoma City bombing, and the 2001 terrorist attacks have all generated elaborate stories of hidden plots. What is far less known is the extent to which conspiracist worldviews have recently become linked in strange and unpredictable ways with other "fringe" notions such as a belief in UFOs, Nostradamus, and the Illuminati. Unraveling the extraordinary genealogies and permutations of these increasingly widespread ideas, Barkun shows how this web of urban legends has spread among subcultures on the Internet and through mass media, how a new style of conspiracy thinking has recently arisen, and how this phenomenon relates to larger changes in American culture. This book, written by a leading expert on the subject, is the most comprehensive and authoritative examination of contemporary American conspiracism to date.Barkun discusses a range of material—involving inner-earth caves, government black helicopters, alien abductions, secret New World Order cabals, and much more—that few realize exists in our culture. Looking closely at the manifestions of these ideas in a wide range of literature and source material from religious and political literature, to New Age and UFO publications, to popular culture phenomena such as The X-Files, and to websites, radio programs, and more, Barkun finds that America is in the throes of an unrivaled period of millennarian activity. His book underscores the importance of understanding why this phenomenon is now spreading into more mainstream segments of American culture.

    As the mosquito transformed the landscapes of civilization, humans were unwittingly required to respond to its piercing impact and universal projection of power.The mosquito has determined the fates of empires and nations, razed and crippled economies, and decided the outcome of pivotal wars, killing nearly half of humanity along the way. She (only females bite) has dispatched an estimated 52 billion people from a total of 108 billion throughout our relatively brief existence. As the greatest purveyor of extermination we have ever known, she has played a greater role in shaping our human story than any other living thing with which we share our global village.Imagine for a moment a world without deadly mosquitoes, or any mosquitoes, for that matter? Our history and the world we know, or think we know, would be completely unrecognizable.Driven by surprising insights and fast-paced storytelling, The Mosquito is the extraordinary untold story of the mosquito's reign through human history and her indelible impact on our modern world order.

    The book traces the intellectual underpinnings of the two groups in the writings of Herbert Marcuse and Norman O. Brown, Allan Ginsberg and Paul Goodman.

    The twentieth century—a time of unprecedented progress—has produced a tremendous strain on the very elements that comprise life itself: This raises the key question of the twenty-first century: How much longer can this go on? With wit and erudition, Ronald Wright lays out a-convincing case that history has always provided an answer, whether we care to notice or not. From Neanderthal man to the Sumerians to the Roman Empire, A Short History of Progress dissects the cyclical nature of humanity's development and demise, the 10,000-year old experiment that we've unleashed but have yet to control. It is Wright's contention that only by understanding and ultimately breaking from the patterns of progress and disaster that humanity has repeated around the world since the Stone Age can we avoid the onset of a new Dark Age. Wright illustrates how various cultures throughout history have literally manufactured their own end by producing an overabundance of innovation and stripping bare the very elements that allowed them to initially advance. Wright's book is brilliant; a fascinating rumination on the hubris at the heart of human development and the pitfalls we still may have time to avoid.

    In this wide-ranging, interdisciplinary study, Andrew C. Isenberg argues that the cultural and ecological encounter between Native Americans and Euroamericans in the Great Plains was the central cause of the near extinction of the bison. Drought and the incursion of domestic livestock and exotic species such as horses into the Great Plains all threatened the Western ecosystem, which was further destabilized as interactions between Native Americans and Euroamericans created new types of hunters in both cultures: mounted Indian nomads and white commercial hide hunters. In the early twentieth century, nostalgia about the very cultural strife that first threatened the bison became, ironically, an important impetus to its preservation.

    In the midst of all this death, a bizarre disease appeared in Europe. Eventually known as encephalitis lethargica, or sleeping sickness, it would spread across the world, leaving millions dead or locked in institutions. Then, in 1927, it would disappear as suddenly as it had arrived-or so the doctors at first thought. Asleep, set in 1920s and '30s New York, follows a group of neurologists through hospitals and insane asylums as they try to solve this worldwide epidemic. The symptoms could include not only unending sleep but dangerous insomnia, facial tics, catatonia, Parkinson's, and even violent insanity. Molly Caldwell Crosby, acclaimed author of The American Plague, explores the frightening history of this forgotten disease- and details the frantic effort to conquer it before it strikes again.

    The volcano's massive sulfate dust cloud enveloped the Earth, cooling temperatures and disrupting major weather systems for more than three years. Communities worldwide endured famine, disease, and civil unrest on a catastrophic scale.Here, Gillen D'Arcy Wood traces Tambora's global and historical reach: how the volcano's three-year climate change regime initiated the first worldwide cholera pandemic, expanded opium markets in China, and plunged the United States into its first economic depression. Bringing the history of this planetary emergency to life, Tambora sheds light on the fragile interdependence of climate and human societies to offer a cautionary tale about the potential tragic impacts of drastic climate change in our own century.

    Outbreak! catalogs fifty of those incidents in gruesome detail, including:The Sweating Sickness that killed 15,000, including Henry VIII's older brotherSyphilis, the "French Disease," which spread throughout Europe in the late fifteenth centuryThe romantic disease: tuberculosis, featured in La Boheme, La Traviata, and Les MiserablesThe worldwide outbreak of influenza in 1918, which killed 3 percent of the populationThe mysterious appearance of HIV in the 1980sThe devastating spread of Ebola in West Africa in 2014From ancient outbreaks of smallpox and plague to modern epidemics such as SARS and Ebola, the stories capture the mystery and devastation brought on by these diseases. It's a sickeningly fun read that confirms the true definition of going viral.