It's also about pain. Most important, it's about how to find the delicate balance between the two, and why now more than ever finding balance is essential. We're living in a time of unprecedented access to high-reward, high-dopamine stimuli: drugs, food, news, gambling, shopping, gaming, texting, sexting, Facebooking, Instagramming, YouTubing, tweeting... The increased numbers, variety, and potency is staggering. The smartphone is the modern-day hypodermic needle, delivering digital dopamine 24/7 for a wired generation. As such we've all become vulnerable to compulsive overconsumption.In Dopamine Nation, Dr. Anna Lembke, psychiatrist and author, explores the exciting new scientific discoveries that explain why the relentless pursuit of pleasure leads to pain...and what to do about it. Condensing complex neuroscience into easy-to-understand metaphors, Lembke illustrates how finding contentment and connectedness means keeping dopamine in check. The lived experiences of her patients are the gripping fabric of her narrative. Their riveting stories of suffering and redemption give us all hope for managing our consumption and transforming our lives. In essence, Dopamine Nation shows that the secret to finding balance is combining the science of desire with the wisdom of recovery."Brilliant... riveting, scary, cogent, and cleverly argued."--Beth Macy, author of DopesickINSTANT NEW YORK TIMES and LOS ANGELES TIMES BESTSELLER“Brilliant… riveting, scary, cogent, and cleverly argued.”—Beth Macy, author of DopesickAs heard on Fresh Air

    He had started in the film industry as a lawyer and worked his way up to become a big-budget studio producer. He’d helped shepherd one of the most successful comedies in film history. He’d married the love of his life. And then one night, in a few seconds, everything changed.In Blindsight, author Chris Colin unspools the remarkable true story of a horrific accident and the life that followed it. A killer at large. Unlikely twists of fate. Miraculous medical oddities. Otherworldly perceptions. Lewis's is a tale of one man’s love and loss, and of the strange turns awaiting a life remade.

    Table of Contents General Information Vol I Diversity in the Living World Structural Organisation in Plants and Animals Cell Structure and Function Plant Physiology Human Physiology Vol II Reproduction Genetics and Evolution Biology and Human Welfare Biotechnology and Its Applications Ecology and Environment Some More Additional Topics Assertion and Research Questions top

    Whereas traditional vegetable plots are largely made up of short-lived, annual vegetable plants, perennials are edible plants that live longer than three years. Grown as permaculture plants, they take up less of your time and effort than annual vegetables do.Martin Crawford’s book outlines the benefits of growing perennial vegetables:Perennials provide crops throughout the year, so there’s always something that can be used in the kitchen. You avoid the hungry gap between the end of the winter harvest and the start of the summer harvest of annual vegetables.Perennial vegetables are less work. Once planted, they stay in the ground for many years. They are the classic plants for no-dig gardeners.Unlike annual vegetables, perennial vegetables cover and protect the soil all year round. This maintains the structure of the soil and helps everything growing in it.Humous levels build up and nutrients don’t wash out of soil. (Cultivating the soil for annuals exposes this humous to air on the surface, causing the carbon to be released as carbon dioxide.)Mycorrhizal fungi, critical for storing carbon within the soil, are preserved. (They are killed when soil is constantly dug for annual vegetables.)Perennial plants contain higher levels of mineral nutrients than annuals because perennial vegetables have larger, permanent root systems, capable of using space more efficiently, and they take up more nutrients.How to grow perennial vegetables gives comprehensive advice on all types of perennial vegetable, from ground-cover plants and coppiced trees to plants for bog gardens and edible woodland plants:In Part One Martin Crawford outlines why we should grow perennials. He then explains where and how to grow them in perennial polycultures, in forest garden or aquatic garden settings. He outlines how to propagate them, how to look after them for maximum health and how to harvest them.Part Two is a plant-by-plant reference of over 100 perennial edibles in detail, from familiar ones like rhubarb, Jerusalem artichokes (sunchokes), horseradish and asparagus to less common ones such as skirret, nodding onions, red chicory, Babbington’s leek, scorzonera, sea kale and wild rocket. With beautiful colour photographs and illustrations and plenty of cooking tips throughout, this book offers inspiration and information for all gardeners, whether experienced or beginner.

    After 3.8 billion years humankind is about to start evolving by new rules...From leading geopolitical expert and technology futurist Jamie Metzl comes a groundbreaking exploration of the many ways genetic-engineering is shaking the core foundations of our lives -- sex, war, love, and death.At the dawn of the genetics revolution, our DNA is becoming as readable, writable, and hackable as our information technology. But as humanity starts retooling our own genetic code, the choices we make today will be the difference between realizing breathtaking advances in human well-being and descending into a dangerous and potentially deadly genetic arms race.Enter the laboratories where scientists are turning science fiction into reality. Look towards a future where our deepest beliefs, morals, religions, and politics are challenged like never before and the very essence of what it means to be human is at play. When we can engineer our future children, massively extend our lifespans, build life from scratch, and recreate the plant and animal world, should we?

    Ignatavicius and M. Linda Workman cover all the latest trends, evidence-based treatment guidelines, and additional updated information needed for safe clinical practice in medical-surgical nursing. This seventh edition features an expanded emphasis on patient safety and NCLEX? Examination preparation, new ties to the QSEN priorities for patient safety, and a greater alignment with the language and focus of clinical practice. A new chapter on evidence-based practice and a wealth of effective online learning tools help solidify your mastery of medical-surgical nursing.

    Survival of the fittest or survival of the nicest? Since the dawn of time man has contemplated the mystery of altruism, but it was Darwin who posed the question most starkly. From the selfless ant to the stinging bee to the man laying down his life for a stranger, evolution has yielded a goodness that in theory should never be. Set against the sweeping tale of 150 years of scientific attempts to explain kindness, The Price of Altruism tells for the first time the moving story of the eccentric American genius George Price (1922–1975), as he strives to answer evolution's greatest riddle. An original and penetrating picture of twentieth century thought, it is also a deeply personal journey. From the heights of the Manhattan Project to the inspired equation that explains altruism to the depths of homelessness and despair, Price's life embodies the paradoxes of Darwin’s enigma. His tragic suicide in a squatter’s flat, among the vagabonds to whom he gave all his possessions, provides the ultimate contemplation on the possibility of genuine benevolence. 24 Illustrations.

    The renowned biologist Daniel Chamovitz builds on the original edition to present an intriguing look at how plants themselves experience the world—from the colors they see to the schedules they keep, and now, what they do in fact hear and how they are able to taste. A rare inside look at what life is really like for the grass we walk on, the flowers we sniff, and the trees we climb, What a Plant Knows offers a greater understanding of their place in nature.

    But in Catching Fire, renowned primatologist Richard Wrangham presents a startling alternative: our evolutionary success is the result of cooking. In a groundbreaking theory of our origins, Wrangham shows that the shift from raw to cooked foods was the key factor in human evolution. when our ancestors adapted to using fire, humanity began.Once our hominid ancestors began cooking their food, the human digestive tract shrank and the brain grew. Time once spent chewing tough raw food could be used instead to hunt and to tend camp. Cooking became the basis for pair bonding and marriage, created the household, and even led to a sexual division of labor.Tracing the contemporary implications of our ancestors' diets, Catching Fire sheds new light on how we came to be the social, intelligent, and sexual species we are today. A pathbreaking new theory of human evolution, Catching Fire will provoke controversy and fascinate anyone interested in our ancient origins--or in our modern eating habits.--from the dustjacket

    Wherever you are right now, the chances are that there are worms, woodlice, centipedes, flies, silverfish, wasps, beetles, mice, shrews and much, much more, quietly living within just a few paces of you.Dave Goulson gives us an insight into the fascinating and sometimes weird lives of these creatures, taking us burrowing into the compost heap, digging under the lawn and diving into the garden pond. He explains how our lives and ultimately the fate of humankind are inextricably intertwined with that of earwigs, bees, lacewings and hoverflies, unappreciated heroes of the natural world.The Garden Jungle is at times an immensely serious book, exploring the environmental harm inadvertently done by gardeners who buy intensively reared plants in disposable plastic pots, sprayed with pesticides and grown in peat cut from the ground. Goulson argues that gardens could become places where we can reconnect with nature and rediscover where food comes from. With just a few small changes, our gardens could become a vast network of tiny nature reserves, where humans and wildlife can thrive together in harmony rather than conflict.For anyone who has a garden, and cares about our planet, this book is essential reading.

    And there is no more accomplished and accessible guide than renowned neuroscientist David Eagleman to help us understand the nature and changing texture of that fabric. With his hallmark clarity and enthusiasm he reveals the myriad ways that the brain absorbs experience: developing, redeploying, organizing, and arranging the data it receives from the body's own absorption of external stimuli, which enables us to gain the skills, the facilities, and the practices that make us who we are. Eagleman covers decades of the most important research into the functioning of the brain and presents new discoveries from his own research as well: about the nature of synesthesia, about dreaming, and about wearable devices that are revolutionizing how we think about the five human senses. Finally, Livewired is as deeply informative as it is accessible and brilliantly engaging.

    You'll make an appointment months in advance. You'll probably wait for several hours until you hear "the doctor will see you now"—but only for fifteen minutes! Then you'll wait even longer for lab tests, the results of which you'll likely never see, unless they indicate further (and more invasive) tests, most of which will probably prove unnecessary (much like physicals themselves). And your bill will be astronomical.In The Patient Will See You Now, Eric Topol, one of the nation’s top physicians, shows why medicine does not have to be that way. Instead, you could use your smartphone to get rapid test results from one drop of blood, monitor your vital signs both day and night, and use an artificially intelligent algorithm to receive a diagnosis without having to see a doctor, all at a small fraction of the cost imposed by our modern healthcare system.The change is powered by what Topol calls medicine's "Gutenberg moment." Much as the printing press took learning out of the hands of a priestly class, the mobile internet is doing the same for medicine, giving us unprecedented control over our healthcare. With smartphones in hand, we are no longer beholden to an impersonal and paternalistic system in which "doctor knows best." Medicine has been digitized, Topol argues; now it will be democratized. Computers will replace physicians for many diagnostic tasks, citizen science will give rise to citizen medicine, and enormous data sets will give us new means to attack conditions that have long been incurable. Massive, open, online medicine, where diagnostics are done by Facebook-like comparisons of medical profiles, will enable real-time, real-world research on massive populations. There's no doubt the path forward will be complicated: the medical establishment will resist these changes, and digitized medicine inevitably raises serious issues surrounding privacy. Nevertheless, the result—better, cheaper, and more human health care—will be worth it.Provocative and engrossing, The Patient Will See You Now is essential reading for anyone who thinks they deserve better health care. That is, for all of us.

    Sandor Katz presents the concepts and processes behind fermentation in ways that are simple enough to guide a reader through their first experience making sauerkraut or yogurt, and in-depth enough to provide greater understanding and insight for experienced practitioners.While Katz expertly contextualizes fermentation in terms of biological and cultural evolution, health and nutrition, and even economics, this is primarily a compendium of practical information--how the processes work; parameters for safety; techniques for effective preservation; troubleshooting; and more.With two-color illustrations and extended resources, this book provides essential wisdom for cooks, homesteaders, farmers, gleaners, foragers, and food lovers of any kind who want to develop a deeper understanding and appreciation for arguably the oldest form of food preservation, and part of the roots of culture itself.Readers will find detailed information on fermenting vegetables; sugars into alcohol (meads, wines, and ciders); sour tonic beverages; milk; grains and starchy tubers; beers (and other grain-based alcoholic beverages); beans; seeds; nuts; fish; meat; and eggs, as well as growing mold cultures, using fermentation in agriculture, art, and energy production, and considerations for commercial enterprises. Sandor Katz has introduced what will undoubtedly remain a classic in food literature, and is the first--and only--of its kind.

    Our Inheritance 2. Mendel and Genes 3. Genes and Chromosomes 4. The Search for the GeneDNA 5. DNA Structure and Replication 6. DNA Expression in Proteins 7. Genes, Enzymes, and Metabolism 8. From DNA to Protein 9. Genomes 10. Manipulating GenesRecombinant DNA 11. Isolating Genes and DNA 12. BiotechnologyGenetic Engineering 13. Biotechnology and the Environment 14. Manipulating DNA by PCR and Other Methods 15. DNA in IdentificationForensics 16. DNA and Evolution 17. DNA and Human Evolution 18. Molecular MedicineGenetic Screening 19. Molecular MedicineThe Immune System 20. Molecular MedicineCancer 21. Molecular MedicineGene Therapy 22. Molecular MedicineCloning and Stem Cells 23. Genetics and Agriculture 24. Biotechnology and Agriculture

    You'll learn how to install, configure, operate, manage, and secure the latest release.Covers all the new features and capabilities of the much-anticipated new release of VMware vSphere Discusses the planning, installation, operation, and management for the latest release Reviews migration to the latest vSphere software Offers hands-on instruction and clear explanations with real-world examples Mastering VMware vSphere is the strategic guide you need to maximize the opportunities of virtualization.