Although one in five Americans now takes at least one psychotropic drug, the fact remains that nearly seventy years after doctors first began prescribing them, we still don't know exactly how or why these drugs work--or don't work--on what ails our brains. Blue Dreams offers the explosive story of the discovery, invention, people, and science behind our licensed narcotics, as told by a riveting writer and psychologist who shares her own intimate experience with the highs and lows of psychiatry's drugs. Lauren Slater's account ranges from the earliest, Thorazine and lithium, up through Prozac and other antidepressants, as well as Ecstasy, "magic mushrooms," the most cutting-edge memory drugs, and even neural implants. Along the way, she narrates the history of psychiatry itself, illuminating the imprint its colorful little capsules have left on millions of brains worldwide, and demonstrating how these wonder drugs may heal us or hurt us.

    But the so-called Dark Ages also gave us the first universities, eyeglasses, and mechanical clocks, proving that the Middle Ages were home to a vibrant scientific culture.In The Light Ages, Cambridge science historian Seb Falk takes us on an immersive tour of medieval science through the story of one fourteenth-century monk, John of Westwyk. From multiplying Roman numerals to navigating by the stars, curing disease, and telling time with an ancient astrolabe, we learn emerging science alongside Westwyk, while following the gripping story of the struggles and successes of an ordinary man in a precarious world. An enlightening history that argues that these times weren’t so dark after all, The Light Ages shows how medieval ideas continue to color how we see the world today.

    “I don’t know why I’m telling you this,” people say, spilling confessions. In fall 2002, Krouse accepts a new contract job investigating lawsuits as a private investigator. The role seems perfect for her, but she quickly realizes she has no idea what she’s doing. Then a lawyer named Grayson assigns her to investigate a sexual assault, a college student who was attacked by football players and recruits at a party a year earlier. Krouse knows she should turn the assignment down; her own history with sexual violence makes it all too personal. But she takes the job anyway, inspired by Grayson’s conviction that he could help change things forever--and maybe she could, too.Over the next five years, Krouse learns everything she can about P. I. technique, tracking down witnesses and investigating a culture of sexual assault and harassment ingrained in the university’s football program. But as the investigation grows into a national scandal and a historic civil rights case, she finds herself increasingly consumed. When the case and her life both implode at the same time, she must figure out how to help win the case without losing herself.

    Lab 257 blows the lid off the stunning true nature and checkered history of Plum Island. It shows that the seemingly bucolic island in the shadow of New York City is a ticking biological time bomb that none of us can safely ignore.Based on declassified government documents, in-depth interviews, and access to Plum Island itself, this is an eye-opening, suspenseful account of a federal government germ laboratory gone terribly wrong. For the first time, Lab 257 takes you deep inside this secret world and presents startling revelations on virus outbreaks, biological meltdowns, infected workers, the periodic flushing of contaminated raw sewage into area waters, and the insidious connections between Plum Island, Lyme disease, and the deadly West Nile virus. The book also probes what's in store for Plum Island's new owner, the Department of Homeland Security, in this age of bioterrorism.Lab 257 is a call to action for those concerned with protecting present and future generations from preventable biological catastrophes.

    The man strikes the piano player as forgettable.He looks bland and inconspicuous. Not at all what you think a serial killer looks like. But that’s what he is, and tonight, he has his sights set on a gray haired man. He will not be his first victim.Nor will he be his last.The Last Call Killer preyed upon gay men in New York in the ‘80s and ‘90s and had all the hallmarks of the most notorious serial killers. Yet because of the sexuality of his victims, the skyhigh murder rates, and the AIDS epidemic, his murders have been almost entirely forgotten.This gripping true-crime narrative tells the story of the Last Call Killer and the decades-long chase to find him. And at the same time, it paints a portrait of his victims and a vibrant community navigating threat and resilience.

    But in the inevitable condition of aging and death, the goals of medicine seem too frequently to run counter to the interest of the human spirit. Nursing homes, preoccupied with safety, pin patients into railed beds and wheelchairs. Hospitals isolate the dying, checking for vital signs long after the goals of cure have become moot. Doctors, committed to extending life, continue to carry out devastating procedures that in the end extend suffering.Gawande, a practicing surgeon, addresses his profession's ultimate limitation, arguing that quality of life is the desired goal for patients and families. Gawande offers examples of freer, more socially fulfilling models for assisting the infirm and dependent elderly, and he explores the varieties of hospice care to demonstrate that a person's last weeks or months may be rich and dignified.

    Today, it is the most common form of officially classified mental illness. Scott Stossel gracefully guides us across the terrain of an affliction that is pervasive yet too often misunderstood. Drawing on his own long-standing battle with anxiety, Stossel presents an astonishing history, at once intimate and authoritative, of the efforts to understand the condition from medical, cultural, philosophical, and experiential perspectives. He ranges from the earliest medical reports of Galen and Hippocrates, through later observations by Robert Burton and Søren Kierkegaard, to the investigations by great nineteenth-century scientists, such as Charles Darwin, William James, and Sigmund Freud, as they began to explore its sources and causes, to the latest research by neuroscientists and geneticists. Stossel reports on famous individuals who struggled with anxiety, as well as on the afflicted generations of his own family. His portrait of anxiety reveals not only the emotion’s myriad manifestations and the anguish anxiety produces but also the countless psychotherapies, medications, and other (often outlandish) treatments that have been developed to counteract it. Stossel vividly depicts anxiety’s human toll—its crippling impact, its devastating power to paralyze—while at the same time exploring how those who suffer from it find ways to manage and control it. My Age of Anxiety is learned and empathetic, humorous and inspirational, offering the reader great insight into the biological, cultural, and environmental factors that contribute to the affliction.

    There have been other books on Dr Morell's cocktail of treatments for Hitler and Goering's reliance on drugs, but Ohler's book is the first to show how the entire Nazi regime was permeated with drugs - cocaine, heroin, morphine and methamphetamines, the last of these crucial to troops' resilience and partly explaining German victory in 1940. Ohler is explicit that drugs cannot explain Third Reich ideology, but their promiscuous use impaired and confused decision-making, with drastic effects on Hitler and his entourage, who, as the war turned against Germany, took refuge in ever more poorly understood cocktails of stimulants. This chemical euphoria changes how we should think about the Nazi high command and its ability to understand the situation it found itself in by 1944-45. As such Blitzed will force a wider reinterpretation of several key events during the Second World War.

    Recounts stories from her vast case files that are alternately terrifying, tragically comic, and profoundly moving, all while she deals with her best friend and fellow doctor's fight with cancer.

    In A Generation of Sociopaths, Gibney examines the disastrous policies of the most powerful generation in modern history, showing how the Boomers ruthlessly enriched themselves at the expense of future generations.Acting without empathy, prudence, or respect for facts--acting, in other words, as sociopaths--the Boomers turned American dynamism into stagnation, inequality, and bipartisan fiasco. The Boomers have set a time bomb for the 2030s, when damage to Social Security, public finances, and the environment will become catastrophic and possibly irreversible--and when, not coincidentally, Boomers will be dying off. Gibney argues that younger generations have a fleeting window to hold the Boomers accountable and begin restoring America.

    She was ambitious and worked hard; she had just bought an apartment; she was falling in love. But then she started to develop worrying symptoms: her face felt like it was burning whenever she was in front of the computer. Soon this progressed to an intolerance of fluorescent light, then of sunlight itself. The reaction soon spread to her entire body. Now, when her symptoms are at their worst, she must spend months on end in a blacked-out room, losing herself in audio books and elaborate word games in an attempt to ward off despair. It was during this period she began to write this book.

    Reisman weaves together stories about our insides with a unique perspective on life, culture, and the natural world.Jonathan Reisman, M.D.―a physician, adventure traveler and naturalist―brings readers on an odyssey navigating our insides like an explorer discovering a new world with  The Unseen Body . With unique insight, Reisman shows us how understanding mountain watersheds helps to diagnose heart attacks, how the body is made mostly of mucus, not water, and how urine carries within it a tale of humanity’s origins.Through his offbeat adventures in healthcare and travel, Reisman discovers new perspectives on the body: a trip to the Alaskan Arctic reveals that fat is not the enemy, but the hero; a stint in the Himalayas uncovers the boundary where the brain ends and the mind begins; and eating a sheep’s head in Iceland offers a lesson in empathy. By relating rich experiences in far-flung lands and among unique cultures back to the body’s inner workings, he shows how our organs live inextricably intertwined lives―an internal ecosystem reflecting the natural world around us.Reisman offers a new and deeply moving perspective, and helps us make sense of our bodies and how they work in a way readers have never before imagined.

    is the first deep-dive investigation of a hazardous and illicit industry that has created a worldwide epidemic, ravaging communities and overwhelming and confounding government agencies that are challenged to combat it. "A whole new crop of chemicals is radically changing the recreational drug landscape," writes Ben Westhoff. "These are known as Novel Psychoactive Substances (NPS) and they include replacements for known drugs like heroin, cocaine, ecstasy, and marijuana. They are synthetic, made in a laboratory, and are much more potent than traditional drugs"--and all-too-often tragically lethal. Drugs like fentanyl, K2, and Spice--and those with arcane acronyms like 25i-NBOMe-- were all originally conceived in legitimate laboratories for proper scientific and medicinal purposes. Their formulas were then hijacked and manufactured by rogue chemists, largely in China, who change their molecular structures to stay ahead of the law, making the drugs' effects impossible to predict. Westhoff has infiltrated this shadowy world, becoming the first journalist to report from inside an illicit Chinese fentanyls lab and providing startling and original reporting on how China's vast chemical industry operates, and how the Chinese government subsidizes it. He tracks down the little-known scientists who invented these drugs and inadvertently killed thousands, as well as a mysterious drug baron who turned the law upside down in his home country of New Zealand. Poignantly, Westhoff chronicles the lives of addicted users and dealers, families of victims, law enforcement officers, and underground drug awareness organizers in the U.S. and Europe. Together they represent the shocking and riveting full anatomy of a calamity we are just beginning to understand. From its depths, as Westhoff relates, are emerging new strategies that may provide essential long-term solutions to the drug crisis that has affected so many.

    So too is a fat woman, a horny woman, a woman shrieking with laughter. Women who are one or more of these things have heard, or perhaps simply intuited, that we are repugnantly excessive, that we have taken illicit liberties to feel or fuck or eat with abandon. After bellowing like a barn animal in orgasm, hoovering a plate of mashed potatoes, or spraying out spit in the heat of expostulation, we've flinched-ugh, that was so gross. I am so gross. On rare occasions, we might revel in our excess--belting out anthems with our friends over karaoke, perhaps--but in the company of less sympathetic souls, our uncertainty always returns. A woman who is Too Much is a woman who reacts to the world with ardent intensity is a woman familiar to lashes of shame and disapproval, from within as well as without. Written in the tradition of Shrill, Dead Girls, Sex Object and other frank books about the female gaze, TOO MUCH encourages women to reconsider the beauty of their excesses-emotional, physical, and spiritual. Rachel Vorona Cote braids cultural criticism, theory, and storytelling together in her exploration of how culture grinds away our bodies, souls, and sexualities, forcing us into smaller lives than we desire. An erstwhile Victorian scholar, she sees many parallels between that era's fixation on women's "hysterical" behavior and our modern policing of the same; in the space of her writing, you're as likely to encounter Jane Eyre and Lizzie Bennet as you are Britney Spears and Lana Del Rey. This book will tell the story of how women, from then and now, have learned to draw power from their reservoirs of feeling, all that makes us "Too Much."

    By examining fossils and DNA, Shubin shows us that our hands actually resemble fish fins, our head is organized like that of a long-extinct jawless fish, and major parts of our genome look and function like those of worms and bacteria.Shubin makes us see ourselves and our world in a completely new light. Your Inner Fish is science writing at its finest-enlightening, accessible, and told with irresistible enthusiasm.