If America could send a man to the moon, shouldn’t the best surgeons in the world be able to build an artificial heart? In Ticker, Texas Monthly executive editor and two time National Magazine Award winner Mimi Swartz shows just how complex and difficult it can be to replicate one of nature’s greatest creations. Part investigative journalism, part medical mystery, Ticker is a dazzling story of modern innovation, recounting fifty years of false starts, abysmal failures and miraculous triumphs, as experienced by one the world’s foremost heart surgeons, O.H. “Bud” Frazier, who has given his life to saving the un-savable. His journey takes him from a small town in west Texas to one of the country’s most prestigious medical institutions, The Texas Heart Institute, from the halls of Congress to the animal laboratories where calves are fitted with new heart designs. The roadblocks to success —medical setbacks, technological shortcomings, government regulations – are immense. Still, Bud and his associates persist, finding inspiration in the unlikeliest of places. A field beside the Nile irrigated by an Archimedes screw. A hardware store in Brisbane, Australia. A seedy bar on the wrong side of Houston. Until post WWII, heart surgery did not exist. Ticker provides a riveting history of the pioneers who gave their all to the courageous process of cutting into the only organ humans cannot live without. Heart surgeons Michael DeBakey and Denton Cooley, whose feud dominated the dramatic beginnings of heart surgery. Christian Barnaard, who changed the world overnight by performing the first heart transplant. Inventor Robert Jarvik, whose artificial heart made patient Barney Clark a worldwide symbol of both the brilliant promise of technology and the devastating evils of experimentation run amuck. Rich in supporting players, Ticker introduces us to Bud’s brilliant colleagues in his quixotic quest to develop an artificial heart: Billy Cohn, the heart surgeon and inventor who devotes his spare time to the pursuit of magic and music; Daniel Timms, the Brisbane biomedical engineer whose design of a lightweight, pulseless heart with but a single moving part offers a new way forward. And, as government money dries up, the unlikeliest of backers, Houston’s furniture king, Mattress Mack. In a sweeping narrative of one man’s obsession, Swartz raises some of the hardest questions of the human condition. What are the tradeoffs of medical progress? What is the cost, in suffering and resources, of offering patients a few more months, or years of life? Must science do harm to do good? Ticker takes us on an unforgettable journey into the power and mystery of the human heart.

    As gripping as CSI and as eye-opening as Mary Roach’s Stiff, Carney’s The Red Market sheds a blazing new light on the disturbing, billion-dollar business of trading in human body parts, bodies, and child trafficking, raising issues and exposing corruptions almost too bizarre and shocking to imagine.

    It happened a day after she’d been the victim of a pile-on, via Twitter, by fellow porn professionals - punishment for her tweeting something deemed homophobic. A month later, August’s husband, Kevin, connected with Jon Ronson to tell the story of how Twitter bullying killed his wife. What neither Kevin nor Ronson realized was that Ronson would soon hear rumors and secrets hinting at a very different story - something mysterious and unexpected and terrible. In The Last Days of August, Ronson unravels the never-before-told story of what caused this beloved 23-year-old actress’ untimely death.

    Anthony Fauci is a hero. He is anything but. As director of the National Institute of Allergy and Infectious Diseases (NIAID), Dr. Anthony Fauci dispenses $6.1 billion in annual taxpayer-provided funding for scientific research, allowing him to dictate the subject, content, and outcome of scientific health research across the globe. Fauci uses the financial clout at his disposal to wield extraordinary influence over hospitals, universities, journals, and thousands of influential doctors and scientists—whose careers and institutions he has the power to ruin, advance, or reward. During more than a year of painstaking and meticulous research, Robert F. Kennedy Jr. unearthed a shocking story that obliterates media spin on Dr. Fauci . . . and that will alarm every American—Democrat or Republican—who cares about democracy, our Constitution, and the future of our children’s health. The Real Anthony Fauci reveals how “America’s Doctor” launched his career during the early AIDS crisis by partnering with pharmaceutical companies to sabotage safe and effective off-patent therapeutic treatments for AIDS. Fauci orchestrated fraudulent studies, and then pressured US Food and Drug Administration (FDA) regulators into approving a deadly chemotherapy treatment he had good reason to know was worthless against AIDS. Fauci repeatedly violated federal laws to allow his Pharma partners to use impoverished and dark-skinned children as lab rats in deadly experiments with toxic AIDS and cancer chemotherapies. In early 2000, Fauci shook hands with Bill Gates in the library of Gates’ $147 million Seattle mansion, cementing a partnership that would aim to control an increasingly profitable $60 billion global vaccine enterprise with unlimited growth potential. Through funding leverage and carefully cultivated personal relationships with heads of state and leading media and social media institutions, the Pharma-Fauci-Gates alliance exercises dominion over global health policy. The Real Anthony Fauci details how Fauci, Gates, and their cohorts use their control of media outlets, scientific journals, key government and quasi-governmental agencies, global intelligence agencies, and influential scientists and physicians to flood the public with fearful propaganda about COVID-19 virulence and pathogenesis, and to muzzle debate and ruthlessly censor dissent.

    Featuring an original score by composer Jeff Beal (House of Cards, Pollock), Einstein’s electrifying journey toward his greatest achievement is brought vividly to life.The theatrical version of Light Falls was first performed at the World Science Festival in New York City.Full list of narrators includes Graeme Malcolm.©2015 Brian Greene (P)2016 Audible, Inc.

    But if we are supposedly evolution’s greatest creation, why do we have such bad knees? Why do we catch head colds so often—two hundred times more often than a dog does? How come our wrists have so many useless bones? Why is the vast majority of our genetic code pointless? And are we really supposed to swallow and breathe through the same narrow tube? Surely there’s been some kind of mistake. As professor of biology Nathan H. Lents explains in Human Errors, our evolutionary history is nothing if not a litany of mistakes, each more entertaining and enlightening than the last. The human body is one big pile of compromises. But that is also a testament to our greatness: as Lents shows, humans have so many design flaws precisely because we are very, very good at getting around them.   A rollicking, deeply informative tour of humans’ four billion year long evolutionary saga, Human Errors both celebrates our imperfections and offers an unconventional accounting of the cost of our success.

    Hilarious, horrifying and heartbreaking, this diary is everything you wanted to know – and more than a few things you didn't – about life on and off the hospital ward. As seen on ITV's Zoe Ball Book Club This edition includes extra diary entries and a new afterword by the author.

    He writes about families coping with deafness, dwarfism, Down's syndrome, autism, schizophrenia, or multiple severe disabilities; with children who are prodigies, who are conceived in rape, who become criminals, who are transgender. While each of these characteristics is potentially isolating, the experience of difference within families is universal, and Solomon documents triumphs of love over prejudice in every chapter.All parenting turns on a crucial question: to what extent should parents accept their children for who they are, and to what extent they should help them become their best selves. Drawing on ten years of research and interviews with more than three hundred families, Solomon mines the eloquence of ordinary people facing extreme challenges.Elegantly reported by a spectacularly original and compassionate thinker, Far from the Tree explores how people who love each other must struggle to accept each other—a theme in every family’s life.

     A riveting, powerful telling of the story of the grassroots movement of activists, many of them in a life-or-death struggle, who seized upon scientific research to help develop the drugs that turned HIV from a mostly fatal infection to a manageable disease. Ignored by public officials, religious leaders, and the nation at large, and confronted with shame and hatred, this small group of men and women chose to fight for their right to live by educating themselves and demanding to become full partners in the race for effective treatments. Around the globe, 16 million people are alive today thanks to their efforts. Not since the publication of Randy Shilts's classic And the Band Played On has a book measured the AIDS plague in such brutally human, intimate, and soaring terms. In dramatic fashion, we witness the founding of ACT UP and TAG (Treatment Action Group), and the rise of an underground drug market in opposition to the prohibitively expensive (and sometimes toxic) AZT. We watch as these activists learn to become their own researchers, lobbyists, drug smugglers, and clinicians, establishing their own newspapers, research journals, and laboratories, and as they go on to force reform in the nation s disease-fighting agencies. With his unparalleled access to this community David France illuminates the lives of extraordinary characters, including the closeted Wall Street trader-turned-activist, the high school dropout who found purpose battling pharmaceutical giants in New York, the South African physician who helped establish the first officially recognized buyers club at the height of the epidemic, and the public relations executive fighting to save his own life for the sake of his young daughter. Expansive yet richly detailed, this is an insider's account of a pivotal moment in the history of American civil rights. Powerful, heart-wrenching, and finally exhilarating, How to Survive a Plague is destined to become an essential part of the literature of AIDS.

    Have it powdered or granulated, by the teaspoon or cube, dark brown or light brown, refined or raw. Taste it in a thick slice of birthday cake, a palmful of chocolate candies, or a snifter of dark rum. Whatever the form, whatever the treat - sugar drives us wild like nothing else. It’s lingered on our tongues for millennia and found its way into almost every household in the world. Alas, the history of sugar is far from sweet. Long before it was linked to America’s obesity epidemic, sugar was fueling the dark forces of exploitation, colonization, conquest, and slavery. More than just candy and cake, sugar has drastically altered the diets, cultures, and economies of the modern world. How can we love sugar while having a healthy relationship with its bittersweet history? From the earliest cultivation of sugarcane in Asia, to the brutal conditions on colonial sugar plantations, to the multibillion-dollar industry that dominates our grocery aisles today, The History of Sugar offers you a host of surprising insights into human nature. As historian Kelley Fanto Deetz reveals in her fascinating Audible Original, our relationship to this commodity showcases its incredible capacity to lure, to addict, to transform humans to bow to its sweetness at almost all costs - and still bring us together in moments of undeniably delicious joy and celebration.

    It's the late 1960s and homosexuality has only just been legalised, and Jeremy Thorpe, the leader of the Liberal party, has a secret he's desperate to hide. As long as Norman Scott, his beautiful, unstable lover is around, Thorpe's brilliant career is at risk. With the help of his fellow politicians, Thorpe schemes, deceives, embezzles - until he can see only one way to silence Scott for good.The trial of Jeremy Thorpe changed our society forever: it was the moment the British public discovered the truth about its political class. Illuminating the darkest secrets of the Establishment, the Thorpe affair revealed such breath-taking deceit and corruption in an entire section of British society that, at the time, hardly anyone dared believe it could be true.

    So universal and timeless are its tactics for pursuing a competitive advantage that some of the most notable people in government, sports, and the entertainment world have all quoted from its nearly 2500-year-old pages. These six expertly crafted lectures explore this classic's wisdom for staying nimble in an ever-changing environment and for maximizing reward while minimizing risk remains eternally fresh. As war and business become more mental and less physical, human intellect plays an ever greater role in competition-making Sun Tzu's strategies highly relevant to the information age.Through a precise explanation of the original text and case studies, Professor Wilson examines how the seminal work's model of leadership has been applied-and misapplied-throughout the realms of war, politics, business, and beyond. You'll study the text's historical framework and then delve into the critical calculations that must be made prior to war-what Sun Tzu refers to as knowing the enemy, knowing ourselves.By studying real-world examples, you'll come away understanding the qualities effective commanders must possess and the work's practical implications for outmaneuvering competitors in daily life. By taking this course, you will appreciate Sun Tzu's content on a far deeper level.Disclaimer: The views expressed in this course are those of the professor and do not necessarily reflect the position or policy of the U.S. Navy, the U.S. Department of Defense, or the U.S. government.

    As we reel from the latest horror . . . " So begins a new epilogue, illustrating how Columbine became the template for nearly two decades of "spectacle murders." It is a false script, seized upon by a generation of new killers. In the wake of Newtown, Aurora, and Virginia Tech, the imperative to understand the crime that sparked this plague grows more urgent every year.What really happened April 20, 1999? The horror left an indelible stamp on the American psyche, but most of what we "know" is wrong. It wasn't about jocks, Goths, or the Trench Coat Mafia. Dave Cullen was one of the first reporters on scene, and spent ten years on this book-widely recognized as the definitive account. With a keen investigative eye and psychological acumen, he draws on mountains of evidence, insight from the world's leading forensic psychologists, and the killers' own words and drawings-several reproduced in a new appendix. Cullen paints raw portraits of two polar opposite killers. They contrast starkly with the flashes of resilience and redemption among the survivors.

    Together they spent a combined thirty years in prison before finally being exonerated in 2008. Meanwhile, the real killer remained free.The Cadaver King and the Country Dentist chronicles how the courts and Mississippi's death investigation system--a relic of the Jim Crow era--failed to deliver justice for its citizens and recounts the horrifying story of the two men who built successful careers on the back of this system. For nearly two decades, medical examiner Dr. Steven Hayne performed the vast majority of Mississippi's autopsies, while his friend Dr. Michael West, a local dentist, pitched himself as a forensic jack-of-all-trades. Together they became the go-to experts for prosecutors and helped put countless Mississippians in prison. But then some of those convictions began to fall apart. Radley Balko and Tucker Carrington argue that bad forensics, structural racism, and institutional failures are at fault, and raise sobering questions about our criminal justice system's ability to address them.

    In The Boy Who Was Raised as a Dog, he tells their stories of trauma and transformation through the lens of science, revealing the brain's astonishing capacity for healing. Deftly combining unforgettable case histories with his own compassionate, insightful strategies for rehabilitation, Perry explains what exactly happens to the brain when a child is exposed to extreme stress-and reveals the unexpected measures that can be taken to ease a child's pain and help him grow into a healthy adult. Through the stories of children who recover-physically, mentally, and emotionally-from the most devastating circumstances, Perry shows how simple things like surroundings, affection, language, and touch can deeply impact the developing brain, for better or for worse. In this deeply informed and moving book, Bruce Perry dramatically demonstrates that only when we understand the science of the mind can we hope to heal the spirit of even the most wounded child.