In Under the Knife, surgeon Arnold Van de Laar uses his own experience and expertise to tell the witty history of the past, present and future of surgery.From the story of the desperate man from seventeenth-century Amsterdam who grimly cut a stone out of his own bladder to Bob Marley's deadly toe, Under the Knife offers all kinds of fascinating and unforgettable insights into medicine and history via the operating theatre.What happens during an operation? How does the human body respond to being attacked by a knife, a bacterium, a cancer cell or a bullet? And, as medical advances continuously push the boundaries of what medicine can cure, what are the limits of surgery?From the dark centuries of bloodletting and of amputations without anaesthetic to today's sterile, high-tech operating theatres, Under the Knife is both a rich cultural history, and a modern anatomy class for us all.

    In the span of twelve hours, lives can be lost, life-altering medical treatment decisions made, and dreams fulfilled or irrevocably stolen. In Brown’s skilled hands--as both a dedicated nurse and an insightful chronicler of events--we are given an unprecedented view into the individual struggles as well as the larger truths about medicine in this country, and by shift’s end, we have witnessed something profound about hope and healing and humanity. Every day, Theresa Brown holds patients' lives in her hands. On this day there are four. There is Mr. Hampton, a patient with lymphoma to whom Brown is charged with administering a powerful drug that could cure him--or kill him; Sheila, who may have been dangerously misdiagnosed; Candace, a returning patient who arrives (perhaps advisedly) with her own disinfectant wipes, cleansing rituals, and demands; and Dorothy, who after six weeks in the hospital may finally go home. Prioritizing and ministering to their needs takes the kind of skill, sensitivity, and, yes, humor that enable a nurse to be a patient’s most ardent advocate in a medical system marked by heartbreaking dysfunction as well as miraculous success.

    The ice sheet that covers it is 700 miles wide and 1,500 miles long, and is composed of nearly three quadrillion tons of ice. For the last 150 years, explorers and scientists have sought to understand Greenland--at first hoping that it would serve as a gateway to the North Pole, and later coming to realize that it contained essential information about our climate. Locked within this vast and frozen white desert are some of the most profound secrets about our planet and its future. Greenland's ice doesn't just tell us where we've been. More urgently, it tells us where we're headed.In The Ice at the End of the World, Jon Gertner explains how Greenland has evolved from one of earth's last frontiers to its largest scientific laboratory. The history of Greenland's ice begins with the explorers who arrived here at the turn of the twentieth century--first on foot, then on skis, then on crude, motorized sleds--and embarked on grueling expeditions that took as long as a year and often ended in frostbitten tragedy. Their original goal was simple: to conquer Greenland's seemingly infinite interior. Yet their efforts eventually gave way to scientists who built lonely encampments out on the ice and began drilling--one mile, two miles down. Their aim was to pull up ice cores that could reveal the deepest mysteries of earth's past, going back hundreds of thousands of years.Today, scientists from all over the world are deploying every technological tool available to uncover the secrets of this frozen island before it's too late. As Greenland's ice melts and runs off into the sea, it not only threatens to affect hundreds of millions of people who live in coastal areas. It will also have drastic effects on ocean currents, weather systems, economies, and migration patterns.Gertner chronicles the unfathomable hardships, amazing discoveries, and scientific achievements of the Arctic's explorers and researchers with a transporting, deeply intelligent style--and a keen sense of what this work means for the rest of us. The melting ice sheet in Greenland is, in a way, an analog for time. It contains the past. It reflects the present. It can also tell us how much time we might have left.

    Czerski provides the tools to alter the way we see everything around us by linking ordinary objects and occurrences, like popcorn popping, coffee stains, and fridge magnets, to big ideas like climate change, the energy crisis, or innovative medical testing. She provides answers to vexing questions: How do ducks keep their feet warm when walking on ice? Why does it take so long for ketchup to come out of a bottle? Why does milk, when added to tea, look like billowing storm clouds? In an engaging voice at once warm and witty, Czerski shares her stunning breadth of knowledge to lift the veil of familiarity from the ordinary.

    Most scientists didn't recognize the import of Hawking's claims, but Leonard Susskind and Gerard t'Hooft realized the threat, and responded with a counterattack that changed the course of physics.The Black Hole War is the thrilling story of their united effort to reconcile Hawking's revolutionary theories of black holes with their own sense of reality -- effort that would eventually result in Hawking admitting he was wrong, paying up, and Susskind and t'Hooft realizing that our world is a hologram projected from the outer boundaries of space.A brilliant book about modern physics, quantum mechanics, the fate of stars and the deep mysteries of black holes, Leonard Susskind's account of the Black Hole War is mind-bending and exhilarating reading.

    Your brain can't function. You are asked to make decisions about treatment almost immediately, when you are not in your right mind. And yet you pull yourself together and start asking questions. Beside you is your doctor, whose job it is to solve the awful puzzle of bone marrow gone wrong. The two of you are in it together. In When Blood Breaks Down, Mikkael Sekeres, a leading cancer specialist, takes readers on the journey that patient and doctor travel together.Sekeres, who writes regularly for the Well section of the New York Times, tells the compelling stories of three people who receive diagnoses of adult leukemia within hours of each other: Joan, a 48-year-old surgical nurse, a caregiver who becomes a patient; David, a 68-year-old former factory worker who bows to his family's wishes and pursues the most aggressive treatment; and Sarah, a 36-year-old pregnant woman who must decide whether to undergo chemotherapy and put her fetus at risk. We join the intimacy of the conversations Sekeres has with his patients, and watch as he teaches trainees. Along the way, Sekeres also explores leukemia in its different forms and the development of drugs to treat it--describing, among many other fascinating details, the invention of the bone marrow transplant (first performed experimentally on beagles) and a treatment that targets the genetics of leukemia.The lessons to be learned from leukemia, Sekeres shows, are not merely medical; they teach us about courage and grace and defying the odds.

    Despite not having brains or central nervous systems, plants perceive their surroundings with an even greater sensitivity than animals. They efficiently explore and react promptly to potentially damaging external events thanks to their cooperative, shared systems; without any central command centers, they are able to remember prior catastrophic events and to actively adapt to new ones.Every page of Plant Revolution bubbles over with Stefano Mancuso’s infectious love for plants and for the eye-opening research that makes it more and more clear how remarkable our fellow inhabitants on this planet really are. In his hands, complicated science is wonderfully accessible, and he has loaded the book with gorgeous photographs that make for an unforgettable reading experience. Plant Revolution opens the doors to a new understanding of life on earth.

    Recent, massive blooms of billions of jellyfish have clogged power plants, decimated fisheries, and caused millions of dollars of damage. Driven by questions about how overfishing, coastal development, and climate change were contributing to a jellyfish population explosion, Juli embarked on a scientific odyssey. She traveled the globe to meet the biologists who devote their careers to jellies, hitched rides on Japanese fishing boats to see giant jellyfish in the wild, raised jellyfish in her dining room, and throughout it all marveled at the complexity of these alluring and ominous biological wonders.

    Paul A. Ruggieri has seen the good, the bad, and the ugly of his profession. In Confessions of a Surgeon, he pushes open the doors of the O.R. and reveals the inscrutable place where lives are improved, saved, and sometimes lost. He shares the successes, failures, remarkable advances, and camaraderie that make it exciting. He uncovers the truth about the abusive, exhaustive training and the arduous devotion of his old-school education. He explores the twenty-four-hour challenges that come from patients and their loved ones; the ethics of saving the lives of repugnant criminals; the hot-button issues of healthcare, lawsuits, and reimbursements; and the true cost of running a private practice. And he explains the influence of the white coat code of silence and why patients may never know what really transpires during surgery. Ultimately, Dr. Ruggieri lays bare an occupation that to most is as mysterious and unfamiliar as it is misunderstood. His account is passionate, illuminating, and often shocking-an eye-opening, never- before-seen look at real life, and death, in the O.R.

    Sybil became both a pop phenomenon and a revolutionary force in the psychotherapy industry. The book rocketed multiple personality disorder (MPD) into public consciousness and played a major role in having the diagnosis added to the psychiatric bible, Diagnostic and Statistical Manual of Mental Disorders. But what do we really know about how Sybil came to be? In her news-breaking book Sybil Exposed, journalist Debbie Nathan gives proof that the allegedly true story was largely fabricated. The actual identity of Sybil (Shirley Mason) has been available for some years, as has the idea that the book might have been exaggerated. But in Sybil Exposed, Nathan reveals what really powered the legend: a trio of women—the willing patient, her ambitious shrink, and the imaginative journalist who spun their story into bestseller gold. From horrendously irresponsible therapeutic practices—Sybil’s psychiatrist often brought an electroshock machine to Sybil’s apartment and climbed into bed with her while administering the treatment— to calculated business decisions (under an entity they named Sybil, Inc., the women signed a contract designating a three-way split of profits from the book and its spin-offs, including board games, tee shirts, and dolls), the story Nathan unfurls is full of over-the-top behavior. Sybil’s psychiatrist, driven by undisciplined idealism and galloping professional ambition, subjected the young woman to years of antipsychotics, psychedelics, uppers, and downers, including an untold number of injections with Pentothal, once known as “truth serum” but now widely recognized to provoke fantasies. It was during these “treatments” that Sybil produced rambling, garbled, and probably “false-memory”–based narratives of the hideous child abuse that her psychiatrist said caused her MPD. Sybil Exposed uses investigative journalism to tell a fascinating tale that reads like fiction but is fact. Nathan has followed an enormous trail of papers, records, photos, and tapes to unearth the lives and passions of these three women. The Sybil archive became available to the public only recently, and Nathan examined all of it and provides proof that the story was an elaborate fraud—albeit one that the perpetrators may have half-believed. Before Sybil was published, there had been fewer than 200 known cases of MPD; within just a few years after, more than 40,000 people would be diagnosed with it. Set across the twentieth century and rooted in a time when few professional roles were available to women, this is a story of corrosive sexism, unchecked ambition, and shaky theories of psychoanalysis exuberantly and drastically practiced. It is the story of how one modest young woman’s life turned psychiatry on its head and radically changed the course of therapy, and our culture, as well.

    Randall never gave sleep much thought. That is, until he began sleepwalking. One midnight crash into a hallway wall sent him on an investigation into the strange science of sleep.In Dreamland, Randall explores the research that is investigating those dark hours that make up nearly a third of our lives. Taking readers from military battlefields to children’s bedrooms, Dreamland shows that sleep isn't as simple as it seems. Why did the results of one sleep study change the bookmakers’ odds for certain Monday Night Football games? Do women sleep differently than men? And if you happen to kill someone while you are sleepwalking, does that count as murder?This book is a tour of the often odd, sometimes disturbing, and always fascinating things that go on in the peculiar world of sleep. You’ll never look at your pillow the same way again.

    From one of the top cave divers working today—and one of the very few women in her field—Into the Planet blends science, adventure, and memoir to bring readers face-to-face with the terror and beauty of earth’s remaining unknowns and the extremes of human capability.Jill Heinerth—the first person in history to dive deep into an Antarctic iceberg and leader of a team that discovered the ancient watery remains of Mayan civilizations—has descended farther into the inner depths of our planet than any other woman. She takes us into the harrowing split-second decisions that determine whether a diver makes it back to safety, the prejudices that prevent women from pursuing careers underwater, and her endeavor to recover a fallen friend’s body from the confines of a cave. But there’s beauty beyond the danger of diving, and while Heinerth swims beneath our feet in the lifeblood of our planet, she works with biologists discovering new species, physicists tracking climate change, and hydrogeologists examining our finite freshwater reserves. Written with hair-raising intensity, Into the Planet is the first book to deliver an intimate account of cave diving, transporting readers deep into inner space, where fear must be reconciled and a mission’s success balances between knowing one’s limits and pushing the envelope of human endurance.

    That one bite changed her life forever, pulling her into the abyss of a devastating illness that took ten doctors to diagnose and years to recover: Newby had become one of the 300,000 Americans who are afflicted with Lyme disease each year.As a science writer, she was driven to understand why this disease is so misunderstood, and its patients so mistreated. This quest led her to Willy Burgdorfer, the Lyme microbe's discoverer, who revealed that he had developed bug-borne bioweapons during the Cold War, and believed that the Lyme epidemic was started by a military experiment gone wrong.In a superb, meticulous work of narrative journalism, Bitten takes readers on a journey to investigate these claims, from biological weapons facilities to interviews with biosecurity experts and microbiologists doing cutting-edge research, all the while uncovering darker truths about Willy. It also leads her to uncomfortable questions about why Lyme can be so difficult to both diagnose and treat, and why the government is so reluctant to classify chronic Lyme as a disease.A gripping, infectious page-turner, Bitten will shed a terrifying new light on an epidemic that is exacting an incalculable toll on us, upending much of what we believe we know about it.

    They’re detectives who solve mysteries about the human body.Diagnosing patients is about looking for clues, whether a persistent tickle in the back of the throat or confusion and memory loss. Just like detectives, good doctors sift through information until they arrive at the medical solution that fits best.Think you have what it takes to keep up with medical detective work? Find out with this second installment of Dr. Roy Benaroch’s thrilling look at medical mysteries from across history. Continuing the excitement of his earlier Audible Original, Medical Mysteries Across History, Pt.2 features cases involving ancient kings and military leaders, beloved philosophers and popular entertainers. You may know who some of these patients are - but you’ve almost certainly never heard their stories told from a doctor’s point of view.In each instance, you’ll learn about the medicine that was practiced during the patient’s life, and you’ll discover how modern medicine can shed light on the past. You’ll see how every life (and every disease) is a story and that these stories reveal the clues doctors need to make an accurate diagnosis. And you’ll discover that while a lot in medicine has certainly changed, the way doctors approach patients hasn’t changed very much at all.Think you can guess who these 10 mystery patients are? Pay attention. The medical and historical hints are there and waiting for you.©2020 Audible Originals, LLC (P)2020 Audible Originals, LLC.

    From blurry vision, to crooked teeth, ACLs that tear at alarming rates and spines that seem to spend a lifetime falling apart, it's a curious thing that human beings have beaten the odds as a species. After all, we're the only survivors on our branch of the tree of life. Why is it that human mothers have such a life-endangering experience giving birth? And why are there entire medical specialties for teeth and feet? In this funny, wide-ranging and often surprising book, biologist Alex Bezzerides tells us just where we inherited our adaptable, achy, brilliant bodies in the process of evolution.The book traces the delightfully unexpected answers to these questions and many more:Why do we blink?Why don't our teeth regularly fit in our mouths?Why do women menstruate when so many other mammals don't?Why did humans stand up on two legs in the first place?