Your head hurts. You're mildly annoyed as you get the kids ready for school and dress for work yourself. Meanwhile, an epic war is being fought, just below your skin. Millions are fighting and dying for you to be able to complain as you head out the door.So what, exactly, is your immune system?Second only to the human brain in its complexity, it is one of the oldest and most critical facets of life on Earth. Without it, you would die within days. In Immune, Philipp Dettmer, the brains behind the most popular science channel on YouTube, takes readers on a journey through the fortress of the human body and its defenses. There is a constant battle of staggering scale raging within us, full of stories of invasion, strategy, defeat, and noble self-sacrifice. In fact, in the time you've been reading this, your immune system has probably identified and eradicated a cancer cell that started to grow in your body.Each chapter delves into an element of the immune system, including defenses like antibodies and inflammation as well as threats like bacteria, allergies, and cancer, as Dettmer reveals why boosting your immune system is actually nonsense, how parasites sneak their way past your body's defenses, how viruses work, and what goes on in your wounds when you cut yourself.Enlivened by engaging graphics and immersive descriptions, Immune turns one of the most intricate, interconnected, and confusing subjects—immunology—into a gripping adventure through an astonishing alien landscape. Immune is a vital and remarkably fun crash course in what is arguably, and increasingly, the most important system in the body.

    Based on more than two hundred personal interviews with both current and former Scientologists--both famous and less well known--and years of archival research, Lawrence Wright uses his extraordinary investigative skills to uncover for us the inner workings of the Church of Scientology: its origins in the imagination of science-fiction writer L. Ron Hubbard; its struggles to find acceptance as a legitimate (and legally acknowledged) religion; its vast, secret campaign to infiltrate the U.S. government; and its dramatic efforts to grow and prevail after the death of Hubbard.At the book's center, two men whom Wright brings vividly to life, showing how they have made Scientology what it is today: The darkly brilliant L. Ron Hubbard--whose restless, expansive mind invented a new religion tailor-made to prosper in the spiritually troubled post-World War II era. And his successor, David Miscavige--tough and driven, with the unenviable task of preserving the church in the face of ongoing scandals and continual legal assaults.We learn about Scientology's esoteric cosmology; about the auditing process that determines an inductee's state of being; about the Bridge to Total Freedom, through which members gain eternal life. We see the ways in which the church pursues celebrities, such as Tom Cruise and John Travolta, and how young idealists who joined the Sea Org, the church's clergy, whose members often enter as children, signing up with a billion-year contract and working with little pay in poor conditions. We meet men and women "disconnected" from friends and family by the church's policy of shunning critical voices. And we discover, through many firsthand stories, the violence that has long permeated the inner sanctum of the church.In Going Clear, Wright examines what fundamentally makes a religion a religion, and whether Scientology is, in fact, deserving of the constitutional protections achieved in its victory over the IRS. Employing all his exceptional journalistic skills of observations, understanding, and synthesis, and his ability to shape a story into a compelling narrative, Lawrence Wright has given us an evenhanded yet keenly incisive book that goes far beyond an immediate exposé and uncovers the very essence of what makes Scientology the institution it is.

    Before humans ruled the earth, there were wolves. Once abundant in North America, these majestic creatures were hunted to near extinction in the lower 48 states by the 1920s. But in recent decades, conservationists have brought wolves back to the Rockies, igniting a battle over the very soul of the West.With novelistic detail, Nate Blakeslee tells the gripping story of one of these wolves, O-Six, a charismatic alpha female named for the year of her birth. Uncommonly powerful, with gray fur and faint black ovals around each eye, O-Six is a kind and merciful leader, a fiercely intelligent fighter, and a doting mother. She is beloved by wolf watchers, particularly renowned naturalist Rick McIntyre, and becomes something of a social media star, with followers around the world.But as she raises her pups and protects her pack, O-Six is challenged on all fronts: by hunters, who compete with wolves for the elk they both prize; by cattle ranchers who are losing livestock and have the ear of politicians; and by other Yellowstone wolves who are vying for control of the park’s stunningly beautiful Lamar Valley.These forces collide in American Wolf, a riveting multi-generational saga of hardship and triumph that tells a larger story about the ongoing cultural clash in the West—between those fighting for a vanishing way of life and those committed to restoring one of the country’s most iconic landscapes.

    There is no cure. In a few days 90 percent of its victims are dead. A secret military SWAT team of soldiers and scientists is mobilized to stop the outbreak of this exotic "hot" virus. The Hot Zone tells this dramatic story, giving a hair-raising account of the appearance of rare and lethal viruses and their "crashes" into the human race. Shocking, frightening, and impossible to ignore, The Hot Zone proves that truth really is scarier than fiction.

    Now they explore the compulsion through a series of compelling case studies in the vein of Oliver Sacks. With vivid portraits that show us the traits by which you can identify a hoarder's piles on sofas and beds that make the furniture useless, houses that can be navigated only by following small paths called goat trails, vast piles of paper that the hoarders "churn" but never discard, even collections of animals and garbage; Frost and Steketee illuminate the pull that possessions exert on all of us. Whether we're savers, collectors, or compulsive cleaners, very few of us are in fact free of the impulses that drive hoarders to the extremes in which they live. For all of us with complicated relationships to our things, Stuff answers the question of what happens when our stuff starts to own us.

    Originally published in 1931, Only Yesterday has an exuberance and proximity to its subject—the Roaring Twenties in all its scandal and glory—that uniquely captures the feel of the era.

    Drawing on her own fieldwork in the Mediterranean, Africa, Asia, and beyond, archeologist Brenna Hassett explores the long history of urbanization through revolutionary changes written into the bones of the people who lived it.For every major new lifestyle, another way of dying appeared. From the "cradle of civilization" in the ancient Near East to the dawn of agriculture on the American plains, skeletal remains and fossil teeth show evidence of shorter lives, rotten teeth, and growth interrupted. The scarring on human skeletons reveals that getting too close to animals had some terrible consequences, but so did getting too close to too many other people.Each chapter of Built on Bones moves forward in time, discussing in depth humanity's great urban experiment. Hassett explains the diseases, plagues, epidemics, and physical dangers we have unwittingly unleashed upon ourselves throughout the urban past--and, as the world becomes increasingly urbanized, what the future holds for us. In a time when "Paleo" lifestyles are trendy and so many of us feel the pain of the city daily grind, this book asks the critical question: Was it worth it?

    For centuries, the power of zero savored of the demonic; once harnessed, it became the most important tool in mathematics. Zero follows this number from its birth as an Eastern philosophical concept to its struggle for acceptance in Europe and its apotheosis as the mystery of the black hole. Today, zero lies at the heart of one of the biggest scientific controversies of all time, the quest for the theory of everything. Elegant, witty, and enlightening, Zero is a compelling look at the strangest number in the universe and one of the greatest paradoxes of human thought.

    In 2011, a twenty-six-year-old libertarian programmer named Ross Ulbricht launched the ultimate free market: the Silk Road, a clandestine Web site hosted on the Dark Web where anyone could trade anything—drugs, hacking software, forged passports, counterfeit cash, poisons—free of the government’s watchful eye. It wasn’t long before the media got wind of the new Web site where anyone—not just teenagers and weed dealers but terrorists and black hat hackers—could buy and sell contraband detection-free. Spurred by a public outcry, the federal government launched an epic two-year manhunt for the site’s elusive proprietor, with no leads, no witnesses, and no clear jurisdiction. All the investigators knew was that whoever was running the site called himself the Dread Pirate Roberts. The Silk Road quickly ballooned into $1.2 billion enterprise, and Ross embraced his new role as kingpin. He enlisted a loyal crew of allies in high and low places, all as addicted to the danger and thrill of running an illegal marketplace as their customers were to the heroin they sold. Through his network he got wind of the target on his back and took drastic steps to protect himself—including ordering a hit on a former employee. As Ross made plans to disappear forever, the Feds raced against the clock to catch a man they weren’t sure even existed, searching for a needle in the haystack of the global Internet.Drawing on exclusive access to key players and two billion digital words and images Ross left behind, Vanity Fair correspondent and New York Times bestselling author Nick Bilton offers a tale filled with twists and turns, lucky breaks and unbelievable close calls. It’s a story of the boy next door’s ambition gone criminal, spurred on by the clash between the new world of libertarian-leaning, anonymous, decentralized Web advocates and the old world of government control, order, and the rule of law. Filled with unforgettable characters and capped by an astonishing climax, American Kingpin might be dismissed as too outrageous for fiction. But it’s all too real.

    In 1828, when New York City purchased this narrow, two-mile-long island in the East River, it was called Blackwell’s Island. There, over the next hundred years, the city would send its insane, indigent, sick, and criminal. Told through the gripping voices of Blackwell’s inhabitants, as well as the period’s city officials, reformers, and journalists (including the famous Nellie Bly), Stacy Horn has crafted a compelling and chilling narrative.  Damnation Island recreates what daily life was like on the island, what politics shaped it, and what constituted charity and therapy in the nineteenth century. Throughout the book, we return to the extraordinary Blackwell’s missionary Reverend French, champion of the forgotten, as he ministers to these inmates, battles the bureaucratic mazes of the Corrections Department and a corrupt City Hall, testifies at salacious trials, and in his diary wonders about man’s inhumanity to man.   For history fans, and for anyone interested in the ways we care for the least fortunate among us, Damnation Island is an eye-opening look at a closed and secretive world. With a tale that is exceedingly relevant today, Horn shows us how far we’ve come—and how much work still remains.

    Decluttering. A parent's death. Sooner or later, all of us are faced with things we no longer need or want. But when we drop our old clothes and other items off at a local donation center, where do they go? Sometimes across the country-or even halfway across the world-to people and places who find value in what we leave behind.In Secondhand, journalist Adam Minter takes us on an unexpected adventure into the often-hidden, multibillion-dollar industry of reuse: thrift stores in the American Southwest to vintage shops in Tokyo, flea markets in Southeast Asia to used-goods enterprises in Ghana, and more. Along the way, Minter meets the fascinating people who handle-and profit from-our rising tide of discarded stuff, and asks a pressing question: In a world that craves shiny and new, is there room for it all?Secondhand offers hopeful answers and hard truths. A history of the stuff we've used and a contemplation of why we keep buying more, it also reveals the marketing practices, design failures, and racial prejudices that push used items into landfills instead of new homes. Secondhand shows us that it doesn't have to be this way, and what really needs to change to build a sustainable future free of excess stuff.

    A strong gravitational wave will briefly change that distance by less than the thickness of a human hair. We have perhaps less than a few tenths of a second to perform this measurement. And we don’t know if this infinitesimal event will come next month, next year or perhaps in thirty years.In 1916 Einstein predicted the existence of gravitational waves: miniscule ripples in the very fabric of spacetime generated by unfathomably powerful events. If such vibrations could somehow be recorded, we could observe our universe for the first time through sound: the hissing of the Big Bang, the whale-like tunes of collapsing stars, the low tones of merging galaxies, the drumbeat of two black holes collapsing into one. For decades, astrophysicists have searched for a way of doing so…In 2016 a team of hundreds of scientists at work on a billion-dollar experiment made history when they announced the first ever detection of a gravitational wave, confirming Einstein’s prediction. This is their story, and the story of the most sensitive scientific instrument ever made: LIGO.Based on complete access to LIGO and the scientists who created it, Black Hole Blues provides a firsthand account of this astonishing achievement: a compelling, intimate portrait of cutting-edge science at its most awe-inspiring and ambitious.

    As acclaimed popular historian and author of How to Be a Victorian Ruth Goodman shows in her madcap chronicle, Elizabethan England was particularly rank with troublemakers, from snooty needlers who took aim with a cutting “thee,” to lowbrow drunkards with revolting table manners. Goodman draws on advice manuals, court cases, and sermons to offer this colorfully crude portrait of offenses most foul. Mischievous readers will delight in learning how to time your impressions for the biggest laugh, why quoting Shakespeare was poor form, and why curses hurled at women were almost always about sex (and why we shouldn’t be surprised). Bringing her signature “exhilarating and contagious” enthusiasm (Boston Globe), this is a celebration of one of history’s naughtiest periods, when derision was an art form.

    But in One Nation Under God, historian Kevin M. Kruse reveals that the belief that America is fundamentally and formally Christian originated in the 1930s.To fight the “slavery” of FDR’s New Deal, businessmen enlisted religious activists in a campaign for “freedom under God” that culminated in the election of their ally Dwight Eisenhower in 1952. The new president revolutionized the role of religion in American politics. He inaugurated new traditions like the National Prayer Breakfast, as Congress added the phrase “under God” to the Pledge of Allegiance and made “In God We Trust” the country’s first official motto. Church membership soon soared to an all-time high of 69 percent. Americans across the religious and political spectrum agreed that their country was “one nation under God.”Provocative and authoritative, One Nation Under God reveals how an unholy alliance of money, religion, and politics created a false origin story that continues to define and divide American politics to this day.

    Bishop explains how our destructive cycles come down to the way that we’re wired. He then identifies different types of people and the ways we fu*k ourselves over: We can’t save money. We land in the same type of toxic relationship. We’re stuck in a rut at work. Analyzing why we act the way we do, including what our common grenades are that blow up our lives, Bishop then shows how we can interrupt the cycle and stop self-sabotaging our lives.Written in the same in your face style as Unfu*k Yourself, Stop Doing that Sh*t will help us get in touch with our psychological machinery so we learn to interrupt negative thoughts and behavior before they start, allowing us to give our attention to something else, and start to find success in the areas we thought we never could.We can take back our lives. We may have fu*ked up in the past, but Stop Doing That Sh*t will show us how to break the patterns in order to live the lives we yearn to have.