The fastest growing of these is Parkinson's: the number of people with Parkinson's doubled to over 6 million over the last 25 years and is projected to double again by 2040. Harmful pesticides known to cause Parkinson's proliferate, many people remain undiagnosed and untreated, research funding stagnates, and the most effective treatment is now a half century old. In Ending Parkinson's Disease, four leading doctors and advocates offer a bold but actionable pact to prevent, advocate for, care for, and treat one of the great health challenges of our time. This is a critical guide for anyone who has or could be touched by this disease.

    While this has had the positive effect of equalizing access to knowledge, it also has lowered the bar on what depth of knowledge is required to consider oneself an "expert." A cult of anti-expertise sentiment has coincided with anti-intellectualism, resulting in massively viral yet poorly informed debates ranging from the anti-vaccination movement to attacks on GMOs. This surge in intellectual egalitarianism has altered the landscape of debates-all voices are equal, and "fact" is a subjective term. Browsing WebMD puts one on equal footing with doctors, and Wikipedia allows all to be foreign policy experts, scientists, and more. As Tom Nichols shows in The Death of Expertise, there are a number of reasons why this has occurred-ranging from easy access to Internet search engines to a customer satisfaction model within higher education. The product of these interrelated trends, Nichols argues, is a pervasive distrust of expertise among the public coinciding with an unfounded belief among non-experts that their opinions should have equal standing with those of the experts. The experts are not always right, of course, and Nichols discusses expert failure. The crucial point is that bad decisions by experts can and have been effectively challenged by other well-informed experts. The issue now is that the democratization of information dissemination has created an army of ill-informed citizens who denounce expertise.When challenged, non-experts resort to the false argument that the experts are often wrong. Though it may be true, but the solution is not to jettison expertise as an ideal; it is to improve our expertise. Nichols is certainly not opposed to information democratization, but rather the enlightenment people believe they achieve after superficial internet research. He shows in vivid detail the ways in which this impulse is coursing through our culture and body politic, but the larger goal is to explain the benefits that expertise and rigorous learning regimes bestow upon all societies.

    So what comes next? Growth will resume. But economic uncertainty will worsen, making what comes next not just a boom but a nerve-shattering SONIC BOOM. Gregg Easterbrook - who "writes nothing that is not brilliant" ("Chicago Tribune") - is a fount of unconventional wisdom, and over time, he is almost always proven right. Throughout 2008 and 2009, as the global economy was contracting and the experts were panicking, Easterbrook worked on a book saying prosperity is about to make its next big leap. Will he be right again? SONIC BOOM: Globalization at Mach Speed presents three basic insights. First, if you don't like globalization, brace yourself, because globalization has barely started. Easterbrook contends the world is about to become "far "more globally linked. Second, the next wave of global change will be primarily positive: economic prosperity, knowledge and freedom will increase more in the next 50 years than in all of human history to this point. But before you celebrate, Easterbrook further warns that the next phase of global change is going to drive us crazy. Most things will be good for most people - but nothing will seem certain for anyone. Each SONIC BOOM chapter is based on examples of cities around the world - in the United States, Europe, Russia, China, South America - that represent a significant Sonic Boom trend. With a terrific sense of humor, pitch-perfect reporting and clear, elegant prose, Easterbrook explains why economic recovery is on the horizon but why the next phase of global change will also give everyone one hell of a headache. "Forbes" calls Easterbrook "the best writer on complex topics in the United States" and SONIC BOOM will show you why.

    He exposes the people and organizations that manipulate our perceptions and profit from our anxieties: politicians who win elections by heightening concerns about crime and drug use even as both are declining; advocacy groups that raise money by exaggerating the prevalence of particular diseases; TV news-magazines that monger a new scare every week to garner ratings.

    She finds that you cannot immunize your child, or yourself, from the world.In this bold, fascinating book, Biss investigates the metaphors and myths surrounding our conception of immunity and its implications for the individual and the social body. As she hears more and more fears about vaccines, Biss researches what they mean for her own child, her immediate community, America, and the world, both historically and in the present moment. She extends a conversation with other mothers to meditations on Voltaire's Candide, Bram Stoker's Dracula, Rachel Carson's Silent Spring, Susan Sontag's AIDS and Its Metaphors, and beyond.On Immunity is a moving account of how we are all interconnected-our bodies and our fates.

    In 1950, only 22 percent of American adults were single. Today, more than 50 percent of American adults are single, and 31 million, roughly one out of every seven adults, live alone. People who live alone make up 28 percent of all U.S. households, which makes them more common than any other domestic unit, including the nuclear family. In Going Solo, renowned sociologist and author Eric Klinenberg proves that these numbers are more than just a passing trend. They are, in fact, evidence of the biggest demographic shift since the Baby Boom: we are learning to go solo, and crafting new ways of living in the process.Klinenberg explores the dramatic rise of solo living, and examines the seismic impact it’s having on our culture, business, and politics. Though conventional wisdom tells us that living by oneself leads to loneliness and isolation, Klinenberg shows that most solo dwellers are deeply engaged in social and civic life. In fact, compared with their married counterparts, they are more likely to eat out and exercise, go to art and music classes, attend public events and lectures, and volunteer. There’s even evidence that people who live alone enjoy better mental health than unmarried people who live with others and have more environmentally sustainable lifestyles than families, since they favor urban apartments over large suburban homes. Drawing on over three hundred in-depth interviews with men and women of all ages and every class, Klinenberg reaches a startling conclusion: in a world of ubiquitous media and hyperconnectivity, this way of life can help us discover ourselves and appreciate the pleasure of good company.With eye-opening statistics, original data, and vivid portraits of people who go solo, Klinenberg upends conventional wisdom to deliver the definitive take on how the rise of living alone is transforming the American experience. Going Solo is a powerful and necessary assessment of an unprecedented social change.

    Pinker is the high priest of rationalism' Sunday Times'If you've ever considered taking drugs to make yourself smarter, read Rationality instead. It's cheaper, more entertaining, and more effective' Jonathan Haidt, author of The Righteous MindIn the twenty-first century, humanity is reaching new heights of scientific understanding - and at the same time appears to be losing its mind. How can a species that discovered vaccines for Covid-19 in less than a year produce so much fake news, quack cures and conspiracy theorizing?In Rationality, Pinker rejects the cynical cliché that humans are simply an irrational species - cavemen out of time fatally cursed with biases, fallacies and illusions. After all, we discovered the laws of nature, lengthened and enriched our lives and set the benchmarks for rationality itself. Instead, he explains, we think in ways that suit the low-tech contexts in which we spend most of our lives, but fail to take advantage of the powerful tools of reasoning we have built up over millennia: logic, critical thinking, probability, causal inference, and decision-making under uncertainty. These tools are not a standard part of our educational curricula, and have never been presented clearly and entertainingly in a single book - until now.Rationality matters. It leads to better choices in our lives and in the public sphere, and is the ultimate driver of social justice and moral progress. Brimming with insight and humour, Rationality will enlighten, inspire and empower.'A terrific book, much-needed for our time' Peter Singer

    For two decades, historian Alice Dreger has led a life of extraordinary engagement, combining activist service to victims of unethical medical research with defense of scientists whose work has outraged identity politics activists. With spirit and wit, Dreger offers in Galileo’s Middle Finger an unforgettable vision of the importance of rigorous truth seeking in today’s America, where both the free press and free scholarly inquiry struggle under dire economic and political threats.This illuminating chronicle begins with Dreger’s own research into the treatment of people born intersex (once called hermaphrodites). Realization of the shocking surgical and ethical abuses conducted in the name of “normalizing” intersex children’s gender identities moved Dreger to become an internationally recognized patient rights’ activist. But even as the intersex rights movement succeeded, Dreger began to realize how some fellow progressive activists were employing lies and personal attacks to silence scientists whose data revealed uncomfortable truths about humans. In researching one such case, Dreger suddenly became the target of just these kinds of attacks.Troubled, she decided to try to understand more—to travel the country to ferret out the truth behind various controversies, to obtain a global view of the nature and costs of these battles. Galileo’s Middle Finger describes Dreger’s long and harrowing journeys between the two camps for which she felt equal empathy: social justice activists determined to win and researchers determined to put hard truths before comfort. Ultimately what emerges is a lesson about the intertwining of justice and of truth—and a lesson of the importance of responsible scholars and journalists to our fragile democracy.

    Real stories about the patients, nurses, consulting physicians, and daily life of a busy Emergency Department. Get a glimpse inside the inner workings of an Emergency Department and the staff that works there, caring for patients and their families. From a toddler who can cuss a blue streak, a dead mouse brought into the Emergency Department, to critical resuscitations, these are stories that you will never forget.

    Backed by investors such as Larry Ellison and Tim Draper, Theranos sold shares in a fundraising round that valued the company at $9 billion, putting Holmes's worth at an estimated $4.7 billion. There was just one problem: The technology didn't work.For years, Holmes had been misleading investors, FDA officials, and her own employees. When Carreyrou, working at The Wall Street Journal, got a tip from a former Theranos employee and started asking questions, both Carreyrou and the Journal were threatened with lawsuits. Undaunted, the newspaper ran the first of dozens of Theranos articles in late 2015. By early 2017, the company's value was zero and Holmes faced potential legal action from the government and her investors. Here is the riveting story of the biggest corporate fraud since Enron, a disturbing cautionary tale set amid the bold promises and gold-rush frenzy of Silicon Valley.

    As she gets to know people who strongly oppose many of the ideas she famously champions, Russell Hochschild nevertheless finds common ground and quickly warms to the people she meets – among them a Tea Party activist whose town has been swallowed by a sinkhole caused by a drilling accident – people whose concerns are actually ones that all Americans share: the desire for community, the embrace of family, and hopes for their children. Strangers in Their Own Land goes beyond the commonplace liberal idea that these are people who have been duped into voting against their own interests. Instead, Russell Hochschild finds lives ripped apart by stagnant wages, a loss of home, an elusive American dream – and political choices and views that make sense in the context of their lives. Russell Hochschild draws on her expert knowledge of the sociology of emotion to help us understand what it feels like to live in "red" America. Along the way she finds answers to one of the crucial questions of contemporary American politics: why do the people who would seem to benefit most from "liberal" government intervention abhor the very idea?

    And as outbreaks of COVID-19, Ebola, MERS, and Zika have demonstrated, we are woefully underprepared to deal with the fallout. So what can -- and must -- we do in order to protect ourselves from mankind's deadliest enemy?Drawing on the latest medical science, case studies, policy research, and hard-earned epidemiological lessons, Deadliest Enemy explores the resources and programs we need to develop if we are to keep ourselves safe from infectious disease. The authors show how we could wake up to a reality in which many antibiotics no longer cure, bioterror is a certainty, and the threat of a disastrous influenza or coronavirus pandemic looms ever larger. Only by understanding the challenges we face can we prevent the unthinkable from becoming the inevitable.Deadliest Enemy is high scientific drama, a chronicle of medical mystery and discovery, a reality check, and a practical plan of action.

    Wearing a saddle.... But worse than this was when the proprietor exclaimed to a cheering crowd, “We are taking the dinosaurs back from the evolutionists!” He knew then and there it was time to try and salvage the Land of the Enlightened, buried somewhere in this new Home of the Uninformed.With his razor-sharp wit and erudite reasoning, Pierce delivers a gut-wrenching, side-splitting lament about the glorification of ignorance in the United States, and how a country founded on intellectual curiosity has somehow deteriorated into a nation of simpletons more apt to vote for an American Idol contestant than a presidential candidate.With Idiot America, Pierce's thunderous denunciation is also a secret call to action, as he hopes that somehow, being intelligent will stop being a stigma, and that pinheads will once again be pitied, not celebrated.

    this is one of those rare books that will change your beliefs - and in doing so will change your life. tHE ANt AND tHE FERRARI offers readers a clear, navigable path through the big questions that confront us all today. What is the meaning of life? Can we be ethical beings in today's world? Can we know if there is life after death? Is there such a thing as Absolute truth? What caused the Big Bang and why should you care?

    But which one? And how?Over the past fifty years, more than three hundred infectious diseases have either newly emerged or reemerged, appearing in territories where they’ve never been seen before. Ninety percent of epidemiologists expect that one of them will cause a deadly pandemic sometime in the next two generations. It could be Ebola, avian flu, a drug-resistant superbug, or something completely new. While we can’t know which pathogen will cause the next pandemic, by unraveling the story of how pathogens have caused pandemics in the past, we can make predictions about the future. In Pandemic: Tracking Contagions, from Cholera to Ebola and Beyond, the prizewinning journalist Sonia Shah—whose book on malaria, The Fever, was called a “tour-de-force history” (The New York Times) and “revelatory” (The New Republic)—interweaves history, original reportage, and personal narrative to explore the origins of contagions, drawing parallels between cholera, one of history’s most deadly and disruptive pandemic-causing pathogens, and the new diseases that stalk humankind today.To reveal how a new pandemic might develop, Sonia Shah tracks each stage of cholera’s dramatic journey, from its emergence in the South Asian hinterlands as a harmless microbe to its rapid dispersal across the nineteenth-century world, all the way to its latest beachhead in Haiti. Along the way she reports on the pathogens now following in cholera’s footsteps, from the MRSA bacterium that besieges her own family to the never-before-seen killers coming out of China’s wet markets, the surgical wards of New Delhi, and the suburban backyards of the East Coast.By delving into the convoluted science, strange politics, and checkered history of one of the world’s deadliest diseases, Pandemic reveals what the next global contagion might look like— and what we can do to prevent it.