She conjures up early operating theaters--no place for the squeamish--and surgeons, working before anesthesia, who were lauded for their speed and brute strength. These medical pioneers knew that the aftermath of surgery was often more dangerous than their patients' afflictions, and they were baffled by the persistent infections that kept mortality rates stubbornly high. At a time when surgery couldn't have been more hazardous, an unlikely figure stepped forward: a young, melancholy Quaker surgeon named Joseph Lister, who would solve the deadly riddle and change the course of history.Fitzharris dramatically recounts Lister's discoveries in gripping detail, culminating in his audacious claim that germs were the source of all infection--and could be countered by antiseptics. Focusing on the tumultuous period from 1850 to 1875, she introduces us to Lister and his contemporaries--some of them brilliant, some outright criminal--and takes us through the grimy medical schools and dreary hospitals where they learned their art, the deadhouses where they studied anatomy, and the graveyards they occasionally ransacked for cadavers.Eerie and illuminating, The Butchering Art celebrates the triumph of a visionary surgeon whose quest to unite science and medicine delivered us into the modern world.

      Along the way, he reveals the untold story of Hans Asperger, the father of Asperger’s syndrome, whose “little professors” were targeted by the darkest social-engineering experiment in human history; exposes the covert campaign by child psychiatrist Leo Kanner to suppress knowledge of the autism spectrum for fifty years; and casts light on the growing movement of "neurodiversity" activists seeking respect, support, technological innovation, accommodations in the workplace and in education, and the right to self-determination for those with cognitive differences.

    But if we are supposedly evolution’s greatest creation, why do we have such bad knees? Why do we catch head colds so often—two hundred times more often than a dog does? How come our wrists have so many useless bones? Why is the vast majority of our genetic code pointless? And are we really supposed to swallow and breathe through the same narrow tube? Surely there’s been some kind of mistake. As professor of biology Nathan H. Lents explains in Human Errors, our evolutionary history is nothing if not a litany of mistakes, each more entertaining and enlightening than the last. The human body is one big pile of compromises. But that is also a testament to our greatness: as Lents shows, humans have so many design flaws precisely because we are very, very good at getting around them.   A rollicking, deeply informative tour of humans’ four billion year long evolutionary saga, Human Errors both celebrates our imperfections and offers an unconventional accounting of the cost of our success.

    Wilczek’s groundbreaking work in quantum physics was inspired by his intuition to look for a deeper order of beauty in nature. In fact, every major advance in his career came from this intuition: to assume that the universe embodies beautiful forms, forms whose hallmarks are symmetry—harmony, balance, proportion—and economy. There are other meanings of “beauty,” but this is the deep logic of the universe—and it is no accident that it is also at the heart of what we find aesthetically pleasing and inspiring.Wilczek is hardly alone among great scientists in charting his course using beauty as his compass. As he reveals in A Beautiful Question, this has been the heart of scientific pursuit from Pythagoras, the ancient Greek who was the first to argue that “all things are number,” to Galileo, Newton, Maxwell, Einstein, and into the deep waters of twentiethcentury physics. Though the ancients weren’t right about everything, their ardent belief in the music of the spheres has proved true down to the quantum level. Indeed, Wilczek explores just how intertwined our ideas about beauty and art are with our scientific understanding of the cosmos.Wilczek brings us right to the edge of knowledge today, where the core insights of even the craziest quantum ideas apply principles we all understand. The equations for atoms and light are almost literally the same equations that govern musical instruments and sound; the subatomic particles that are responsible for most of our mass are determined by simple geometric symmetries. The universe itself, suggests Wilczek, seems to want to embody beautiful and elegant forms. Perhaps this force is the pure elegance of numbers, perhaps the work of a higher being, or somewhere between. Either way, we don’t depart from the infinite and infinitesimal after all; we’re profoundly connected to them, and we connect them. When we find that our sense of beauty is realized in the physical world, we are discovering something about the world, but also something about ourselves.Gorgeously illustrated, A Beautiful Question is a mind-shifting book that braids the age-old quest for beauty and the age-old quest for truth into a thrilling synthesis. It is a dazzling and important work from one of our best thinkers, whose humor and infectious sense of wonder animate every page. Yes: The world is a work of art, and its deepest truths are ones we already feel, as if they were somehow written in our souls.

    Updated to reflect the latest research in the field, and enhanced with more than 1,000 illustrations, most in full-color, the 12th Edition is the most comprehensive and modern approach to understanding medical histology available anywhere.Features: NEW full-color micrographs that comprise a complete atlas of tissue sections highlight the important features of every tissue and organ in the human body. New full-color, easy-to-understand drawings provide just the right level of detail necessary to clarify the text and make learning easier A valuable introductory chapter on laboratory methods used for the study of tissues, including the most important types of microscopy A logical organization that features chapters focusing on the cytoplasmic and nuclear compartment of the cell, the four basic tissues that form the organs, and each organ system Expanded legends that accompany each figure emphasize important points and eliminate the need to jump from image to text Medical applications explain the clinical relevance of each topic Complete coverage of every tissue of the body CD-ROM with all the images from the textVisit www.LangeTextbooks.com to access valuable resources and study aids

    A comprehensive introduction that provides important background on the origins and spread of the plague is followed by nearly 50 documents organized into topical sections that focus on the origin and spread of the illness; the responses of medical practitioners; the societal and economic impact; religious responses; the flagellant movement and attacks on Jews provoked by the plague; and the artistic response. Each chapter has an introduction that summarizes the issues explored in the documents; headnotes to the documents provide additional background material. The book contains documents from many countries — including Muslim and Byzantine sources — to give students a variety of perspectives on this devastating illness and its consequences. The volume also includes illustrations, a chronology of the Black Death, questions to consider, a selected bibliography, and an index.

    It could be an oddball researcher’s genius insight, a catalyzing moment in geopolitical history, a new breakthrough technology, or an unexpected but welcome side effect discovered during clinical trials. Piece together these stories, as Thomas Hager does in this remarkable, century-spanning history, and you can trace the evolution of our culture and the practice of medicine.  ​Beginning with opium, the “joy plant,” which has been used for 10,000 years, Hager tells a captivating story of medicine. His subjects include the largely forgotten female pioneer who introduced smallpox inoculation to Britain, the infamous knockout drops, the first antibiotic, which saved countless lives, the first antipsychotic, which helped empty public mental hospitals, Viagra, statins, and the new frontier of monoclonal antibodies. This is a deep, wide-ranging, and wildly entertaining book.

    Lieberman illuminates how these ongoing changes have brought many benefits, but also have created novel conditions to which our bodies are not entirely adapted, resulting in a growing incidence of obesity and new but avoidable diseases, including type-2 diabetes. He proposes that many of these chronic illnesses persist and in some cases are intensifying because of "dysevolution," a pernicious dynamic whereby only the symptoms rather than the causes of these maladies are treated. And finally—provocatively—he advocates the use of evolutionary information to help nudge, push, and sometimes oblige us to create a more salubrious environment.(With charts and line drawings throughout.)From the Hardcover edition.

    After a dozen years at the court of Lodovico Sforza, the Duke of Milan, Leonardo was at a low point personally and professionally: at forty-three, in an era when he had almost reached the average life expectancy, he had failed, despite a number of prestigious commissions, to complete anything that truly fulfilled his astonishing promise. His latest failure was a giant bronze horse to honor Sforza's father: His 75 tons of bronze had been expropriated to be turned into cannons to help repel a French invasion of Italy. The commission to paint The Last Supper in the refectory of a Dominican convent was a small compensation, and his odds of completing it were not promising: Not only had he never worked on a painting of such a large size-15' high x 30' wide-but he had no experience in the extremely difficult medium of fresco.  In his compelling new book, Ross King explores how-amid war and the political and religious turmoil around him, and beset by his own insecurities and frustrations-Leonardo created the masterpiece that would forever define him. King unveils dozens of stories that are embedded in the painting. Examining who served as the models for the Apostles, he makes a unique claim: that Leonardo modeled two of them on himself. Reviewing Leonardo's religious beliefs, King paints a much more complex picture than the received wisdom that he was a heretic. The food that Leonardo, a vegetarian, placed on the table reveals as much as do the numerous hand gestures of those at Christ's banquet. As King explains, many of the myths that have grown up around The Last Supper are wrong, but its true story is ever more interesting. Bringing to life a fascinating period in European history, Ross King presents an original portrait of one of the world's greatest geniuses through the lens of his most famous work.

    His method emphasizes speed, confidence, and relaxation, while incorporating many time-saving tricks of the trade.

    . . in which Sydney Padua transforms one of the most compelling scientific collaborations into a hilarious series of adventures. Meet Victorian London’s most dynamic duo: Charles Babbage, the unrealized inventor of the computer, and his accomplice, Ada, Countess of Lovelace, the peculiar protoprogrammer and daughter of Lord Byron. When Lovelace translated a description of Babbage’s plans for an enormous mechanical calculating machine in 1842, she added annotations three times longer than the original work. Her footnotes contained the first appearance of the general computing theory, a hundred years before an actual computer was built. Sadly, Lovelace died of cancer a decade after publishing the paper, and Babbage never built any of his machines. But do not despair! The Thrilling Adventures of Lovelace and Babbage presents a rollicking alternate reality in which Lovelace and Babbage do build the Difference Engine and then use it to build runaway economic models, battle the scourge of spelling errors, explore the wilder realms of mathematics, and, of course, fight crime—for the sake of both London and science. Complete with extensive footnotes that rival those penned by Lovelace herself, historical curiosities, and never-before-seen diagrams of Babbage’s mechanical, steam-powered computer, The Thrilling Adventures of Lovelace and Babbage is wonderfully whimsical, utterly unusual, and, above all, entirely irresistible.(With black-and-white illustrations throughout.)

    However, according to Hofstadter, the formal system that underlies all mental activity transcends the system that supports it. If life can grow out of the formal chemical substrate of the cell, if consciousness can emerge out of a formal system of firing neurons, then so too will computers attain human intelligence. Gödel, Escher, Bach is a wonderful exploration of fascinating ideas at the heart of cognitive science: meaning, reduction, recursion, and much more.

    Many books on the plague rely on statistics to tell the story: how many people died; how farm output and trade declined. But statistics can’t convey what it was like to sit in Siena or Avignon and hear that a thousand people a day are dying two towns away. Or to have to chose between your own life and your duty to a mortally ill child or spouse. Or to live in a society where the bonds of blood and sentiment and law have lost all meaning, where anyone can murder or rape or plunder anyone else without fear of consequence.In The Great Mortality, author John Kelly lends an air of immediacy and intimacy to his telling of the journey of the plague as it traveled from the steppes of Russia, across Europe, and into England, killing 75 million people—one third of the known population—before it vanished.

    Swanson, New York Times bestselling author of Manhunt An Oxford-trained archaeologist and award-winning journalist based in Rome, Vernon Silver brings us The Lost Chalice, the electrifying true story of the race to secure a priceless, 2,500-year-old cup depicting the fall of Troy—a lost treasure crafted by Euphronios, an artist widely considered “the Leonardo Da Vinci of ancient Greece.” A gripping, real life mystery, The Lost Chalice gives readers a behind-the-scenes look at the inner workings of great museums and antiquities collections—exposing a world of greed, backstabbing, and double-dealing.

    The author of The Lives of a Cell and The Medusa and the Snail now raises challenging questions about some of the major issues of our time—AIDS, drug abuse, and aging.With extraordinary perception, author Lewis Thomas discusses topics such as evolutionary biology, the development of language, the therapeutic aspects of medicine, and his love for his profession.